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Results for znf740a+znf740b

Z-value: 1.73

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Transcription factors associated with znf740a+znf740b

Gene Symbol Gene ID Gene Info
znf740b
ENSDARG00000061174 zinc finger protein 740b
znf740a
ENSDARG00000070939 zinc finger protein 740a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf740adr10_dc_chr11_-_2274344_2274483-0.611.3e-02Click!
znf740bdr10_dc_chr23_-_36319185_363193290.048.7e-01Click!

Activity profile of znf740a+znf740b motif

Sorted Z-values of znf740a+znf740b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of znf740a+znf740b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_38834751 5.23 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr23_-_511984 5.19 ENSDART00000055139
col9a3
collagen, type IX, alpha 3
chr14_-_9216303 4.76 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr2_+_23038657 4.74 ENSDART00000089012
kif1ab
kinesin family member 1Ab
chr23_+_36002332 4.44 ENSDART00000103139
hoxc8a
homeobox C8a
chr14_+_21531709 4.07 ENSDART00000144367
ctbp1
C-terminal binding protein 1
chr11_-_23954234 3.93 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr13_-_25067585 3.76 ENSDART00000159585
adka
adenosine kinase a
chr21_-_26459113 3.64 ENSDART00000157255
cd248b
CD248 molecule, endosialin b
KN149987v1_-_29629 3.59 ENSDART00000159555
ENSDART00000168161
ENSDARG00000103311
ENSDARG00000103311
chr18_+_43041488 3.58

chr3_-_60929921 3.52 ENSDART00000055064
pvalb8
parvalbumin 8
chr2_+_43619752 3.41 ENSDART00000142078
ENSDART00000098265
ENSDART00000098267
nrp1b
neuropilin 1b
KN150411v1_-_12184 3.28

chr22_-_95158 3.25

chr25_+_34997593 3.18 ENSDART00000058443
fibina
fin bud initiation factor a
chr22_+_24131239 3.11 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr23_+_32573474 3.09 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr3_+_49277125 3.08 ENSDART00000161724
gas7a
growth arrest-specific 7a
chr23_+_6298911 3.07 ENSDART00000139795
syt2a
synaptotagmin IIa
chr2_-_16896965 3.03 ENSDART00000022549
atp1b3a
ATPase, Na+/K+ transporting, beta 3a polypeptide
chr11_-_4216204 3.02 ENSDART00000121716
ENSDARG00000086300
ENSDARG00000086300
chr5_-_39910235 3.02 ENSDART00000146237
ENSDART00000163302
fsta
follistatin a
chr17_+_27383737 3.00 ENSDART00000156756
FP017274.1
ENSDARG00000097369
chr14_+_33117964 2.99 ENSDART00000075278
atp1b4
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr5_-_70915664 2.97

chr7_-_48392300 2.94

chr2_-_23348612 2.88 ENSDART00000110373
znf414
zinc finger protein 414
chr2_-_39710140 2.84 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr1_-_51862897 2.83 ENSDART00000136469
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr20_+_26639029 2.82 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr14_-_46651359 2.80 ENSDART00000163316
CR383676.1
ENSDARG00000099970
chr18_+_44656323 2.76 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr12_+_29994735 2.74 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr10_-_43711606 2.66 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr10_+_10252074 2.61 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr9_-_34146631 2.60 ENSDART00000177897
AL590134.2
ENSDARG00000107869
chr21_+_5528438 2.56 ENSDART00000168158
shroom3
shroom family member 3
chr9_+_12988528 2.52 ENSDART00000125961
bmpr2b
bone morphogenetic protein receptor, type II b (serine/threonine kinase)
chr23_+_6043862 2.51

chr13_-_508202 2.48 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr1_-_37990863 2.48 ENSDART00000132402
gpm6ab
glycoprotein M6Ab
chr17_+_52736192 2.42 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr4_-_12863235 2.41 ENSDART00000080536
hmga2
high mobility group AT-hook 2
chr20_-_35343242 2.35 ENSDART00000113294
fzd3a
frizzled class receptor 3a
chr16_-_9108885 2.35 ENSDART00000153785
triob
trio Rho guanine nucleotide exchange factor b
chr21_+_5483017 2.33 ENSDART00000160885
stbd1
starch binding domain 1
chr7_-_69399273 2.32 ENSDART00000159823
ENSDART00000075178
ENSDART00000168942
ENSDART00000126739
tspan5a
tetraspanin 5a
chr3_-_60930025 2.28 ENSDART00000055064
pvalb8
parvalbumin 8
chr13_-_31304614 2.28

chr17_-_20830287 2.28 ENSDART00000149630
ank3a
ankyrin 3a
chr20_+_47524781 2.27

chr2_-_26872047 2.25 ENSDART00000138693
si:ch211-106k21.5
si:ch211-106k21.5
chr2_-_44330405 2.22 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr1_-_11286438 2.21 ENSDART00000159981
ENSDART00000066638
grk4
G protein-coupled receptor kinase 4
chr1_-_50831155 2.21 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr13_-_45386047 2.20 ENSDART00000137566
rhd
Rh blood group, D antigen
chr5_+_42312784 2.19 ENSDART00000039973
rufy3
RUN and FYVE domain containing 3
chr8_-_52952226 2.19 ENSDART00000168185
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr10_-_31619761 2.18 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr5_-_13844114 2.18

chr2_-_44893769 2.15 ENSDART00000041806
acsm3
acyl-CoA synthetase medium-chain family member 3
chr21_-_30144979 2.14 ENSDART00000065447
hnrnph1l
heterogeneous nuclear ribonucleoprotein H1, like
chr22_+_24131297 2.13 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr15_-_5827067 2.13 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr11_+_38013238 2.10 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr20_+_20772543 2.10 ENSDART00000152481
rtn1b
reticulon 1b
chr22_+_28496424 2.08 ENSDART00000089546
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr7_+_71096788 2.08 ENSDART00000161871
sod3a
superoxide dismutase 3, extracellular a
chr11_-_25803101 2.08 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr10_+_22759607 2.07

chr10_+_24476213 2.07 ENSDART00000146370
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_+_32183937 2.06 ENSDART00000147474
stmn2b
stathmin 2b
chr9_-_31467299 2.06 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr5_-_47519273 2.05

chr9_-_32942783 2.05 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr5_+_68410884 2.04 ENSDART00000153691
CU928129.1
ENSDARG00000097815
chr10_+_1812271 2.01

KN150342v1_-_59821 1.97 ENSDART00000163274
ENSDARG00000100757
ENSDARG00000100757
chr6_-_43679553 1.96 ENSDART00000150128
foxp1b
forkhead box P1b
chr10_+_9134634 1.96 ENSDART00000110443
fstb
follistatin b
chr23_+_22763861 1.95

chr9_+_7609372 1.93

chr7_+_28862183 1.92 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr11_+_1996358 1.90

chr17_-_20830398 1.89 ENSDART00000149630
ank3a
ankyrin 3a
chr25_+_36796176 1.88 ENSDART00000170289
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr25_+_36796226 1.85 ENSDART00000170289
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr16_+_22672315 1.82 ENSDART00000142241
she
Src homology 2 domain containing E
chr6_+_54231519 1.80 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr12_-_7820226 1.78 ENSDART00000149594
ENSDART00000148866
ank3b
ankyrin 3b
chr12_+_13206107 1.78 ENSDART00000105896
atp2a1l
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like
chr13_+_1484997 1.76

chr16_+_25845432 1.75

chr10_-_43466392 1.75 ENSDART00000062631
hapln1b
hyaluronan and proteoglycan link protein 1b
chr7_+_16583234 1.75 ENSDART00000173580
nav2a
neuron navigator 2a
chr17_-_52735615 1.74

chr18_+_35994461 1.73

chr9_+_56182756 1.73 ENSDART00000144757
mxra5b
matrix-remodelling associated 5b
chr23_-_41756325 1.68 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr24_-_16994956 1.67 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr2_+_24135188 1.67 ENSDART00000041877
csrnp1a
cysteine-serine-rich nuclear protein 1a
chr14_+_23986703 1.66 ENSDART00000079164
klhl3
kelch-like family member 3
chr13_-_37339615 1.66 ENSDART00000100324
ppp2r5eb
protein phosphatase 2, regulatory subunit B', epsilon isoform b
chr20_-_53271601 1.65

chr4_+_11312432 1.65 ENSDART00000051792
sema3aa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr10_-_43466478 1.62 ENSDART00000062631
hapln1b
hyaluronan and proteoglycan link protein 1b
chr17_-_37040941 1.61 ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr13_-_14978365 1.61

chr16_-_31476944 1.61 ENSDART00000167350
zgc:194210
zgc:194210
chr9_+_5884066 1.60 ENSDART00000129117
pdzk1
PDZ domain containing 1
chr5_-_13826859 1.58 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr24_-_16995194 1.56 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr10_-_43711513 1.56 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr20_-_35343057 1.56 ENSDART00000113294
fzd3a
frizzled class receptor 3a
chr11_+_40945681 1.55

chr2_-_4277516 1.53

chr16_+_10974655 1.53

chr11_+_18823629 1.52

chr7_+_34394526 1.51

chr9_+_7609527 1.51

chr11_-_37921642 1.48

chr7_+_890752 1.48 ENSDART00000111531
epdl1
ependymin-like 1
chr18_+_17564926 1.47

chr24_+_30343717 1.47 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr3_+_22412059 1.46

chr14_+_31226164 1.45 ENSDART00000002684
ddx26b
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr12_+_5495284 1.45 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr20_+_25441689 1.44 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr3_+_40667131 1.40 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr1_-_45941709 1.39 ENSDART00000053232
cdadc1
cytidine and dCMP deaminase domain containing 1
chr3_+_23573114 1.38 ENSDART00000024256
hoxb6a
homeobox B6a
chr22_-_15182840 1.35

chr21_+_18295124 1.34 ENSDART00000167511
ENSDARG00000104101
ENSDARG00000104101
chr25_+_33364224 1.33 ENSDART00000121449
roraa
RAR-related orphan receptor A, paralog a
chr3_+_14238188 1.33 ENSDART00000165452
ENSDART00000171726
tmem56b
transmembrane protein 56b
chr3_+_52901602 1.32 ENSDART00000114343
brd4
bromodomain containing 4
chr25_-_7346766 1.32 ENSDART00000170050
cdkn1cb
cyclin-dependent kinase inhibitor 1Cb
chr18_-_26876598 1.32

chr11_-_18542803 1.31 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr18_+_21133694 1.31 ENSDART00000060015
chka
choline kinase alpha
chr22_-_15930756 1.29 ENSDART00000080047
eps15l1a
epidermal growth factor receptor pathway substrate 15-like 1a
chr5_-_63031745 1.29

chr23_-_17543731 1.28 ENSDART00000002398
trim101
tripartite motif containing 101
chr1_-_57980632 1.28 ENSDART00000100152
sid4
secreted immunoglobulin domain 4
chr21_-_14950265 1.27 ENSDART00000178507
mmp17a
matrix metallopeptidase 17a
chr4_+_25231425 1.27 ENSDART00000066934
itih5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr21_+_13236509 1.27

chr23_+_35984675 1.26 ENSDART00000053295
hoxc10a
homeobox C10a
chr15_+_3296905 1.26 ENSDART00000171723
foxo1a
forkhead box O1 a
chr19_+_43414160 1.26 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr20_-_28739099 1.25 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr5_+_36014029 1.25 ENSDART00000150574
nova1
neuro-oncological ventral antigen 1
chr12_+_35912088 1.23 ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr6_-_43679476 1.22 ENSDART00000150128
foxp1b
forkhead box P1b
chr25_+_30535271 1.20

chr7_-_68417190 1.20

chr11_+_38013564 1.17 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr1_-_57980586 1.16 ENSDART00000100152
sid4
secreted immunoglobulin domain 4
chr18_-_48996702 1.16 ENSDART00000125432
esrrd
estrogen-related receptor delta
chr16_-_8367090 1.15 ENSDART00000129068
entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr3_+_21059221 1.13 ENSDART00000078807
zgc:123295
zgc:123295
chr2_-_54965656 1.10

chr5_+_29327479 1.10

chr23_+_36002475 1.10 ENSDART00000103139
hoxc8a
homeobox C8a
chr2_-_6139895 1.09 ENSDART00000147509
si:ch211-284b7.3
si:ch211-284b7.3
chr2_+_47885551 1.09

chr24_+_9911748 1.08

chr8_+_8252892 1.08 ENSDART00000170566
srpk3
SRSF protein kinase 3
chr17_+_8874210 1.08

chr5_+_30099073 1.08 ENSDART00000012888
atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr13_-_508050 1.07 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr7_-_28339836 1.04 ENSDART00000054366
scube2
signal peptide, CUB domain, EGF-like 2
chr1_-_37990935 1.01 ENSDART00000132402
gpm6ab
glycoprotein M6Ab
chr3_-_25239180 1.01 ENSDART00000055491
smurf2
SMAD specific E3 ubiquitin protein ligase 2
chr15_-_10532992 1.01 ENSDART00000175825
tenm4
teneurin transmembrane protein 4
chr24_+_30343687 0.99 ENSDART00000162377
FP085414.1
ENSDARG00000100270
KN150342v1_-_60050 0.98 ENSDART00000163274
ENSDARG00000100757
ENSDARG00000100757
chr15_+_43882577 0.97 ENSDART00000010881
naalad2
N-acetylated alpha-linked acidic dipeptidase 2
chr25_-_10992022 0.97 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr22_-_38184317 0.97 ENSDART00000147694
tm4sf4
transmembrane 4 L six family member 4
chr16_+_47493635 0.97 ENSDART00000032309
slc25a32b
solute carrier family 25 (mitochondrial folate carrier), member 32b
chr5_+_29327363 0.97

chr5_+_13870125 0.96

chr3_-_1421391 0.95 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr5_-_18548376 0.94 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr23_+_22763789 0.94

chr10_+_10252239 0.94 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr18_-_34573597 0.93 ENSDART00000021880
ssr3
signal sequence receptor, gamma
chr5_+_60457842 0.92

chr5_-_1498277 0.92

chr18_-_35485470 0.90 ENSDART00000141023
itpkcb
inositol-trisphosphate 3-kinase Cb
chr22_-_20361311 0.90

chr2_+_28906539 0.90 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr7_+_20046613 0.90 ENSDART00000131019
acadvl
acyl-CoA dehydrogenase, very long chain
chr21_+_26696853 0.89 ENSDART00000168379
pcxa
pyruvate carboxylase a
chr17_-_27247075 0.88

chr9_-_53380782 0.88 ENSDART00000166906
trpm2
transient receptor potential cation channel, subfamily M, member 2
chr8_-_387982 0.87

chr21_+_37985816 0.86 ENSDART00000085728
klf8
Kruppel-like factor 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
1.2 4.8 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.9 3.8 GO:0044209 AMP salvage(GO:0044209)
0.8 4.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.8 2.4 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.7 2.2 GO:0051701 interaction with host(GO:0051701)
0.7 2.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.7 5.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.7 2.1 GO:0021742 abducens nucleus development(GO:0021742)
0.6 3.4 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.6 2.2 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.5 2.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.5 3.9 GO:0021754 facial nucleus development(GO:0021754)
0.4 1.3 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.4 2.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 5.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.4 3.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.3 1.0 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.3 1.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.3 2.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 2.1 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.3 1.7 GO:0070293 renal absorption(GO:0070293)
0.3 1.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 1.8 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.2 3.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 0.7 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.2 1.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.0 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.2 4.5 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.2 3.0 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 1.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 5.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.2 2.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 2.8 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.7 GO:0010991 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.0 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 1.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 1.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.7 GO:0051601 exocyst localization(GO:0051601)
0.1 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.6 GO:0001843 neural tube closure(GO:0001843)
0.1 1.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 4.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.4 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 0.3 GO:0030307 positive regulation of cell growth(GO:0030307)
0.1 1.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.9 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 3.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.1 2.8 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.3 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 1.3 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.1 2.2 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 2.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 3.0 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.9 GO:0051289 protein homotetramerization(GO:0051289)
0.0 4.7 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 5.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.4 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 4.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 3.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.7 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 2.4 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.7 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.8 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 1.8 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.1 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 1.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.5 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 1.0 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 6.9 GO:0048812 neuron projection morphogenesis(GO:0048812)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.5 GO:0015718 monocarboxylic acid transport(GO:0015718)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.0 GO:1904949 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.6 4.0 GO:0044295 axonal growth cone(GO:0044295)
0.5 2.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 4.2 GO:0030315 T-tubule(GO:0030315)
0.3 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 2.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.9 GO:1990246 uniplex complex(GO:1990246)
0.1 2.1 GO:0030426 growth cone(GO:0030426)
0.1 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 6.1 GO:0016324 apical plasma membrane(GO:0016324)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.1 12.6 GO:0030424 axon(GO:0030424)
0.1 1.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.7 GO:0000145 exocyst(GO:0000145)
0.1 9.9 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 4.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 1.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 8.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.1 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0004001 adenosine kinase activity(GO:0004001)
1.2 3.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 2.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 2.3 GO:2001070 starch binding(GO:2001070)
0.4 2.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 1.6 GO:0004046 aminoacylase activity(GO:0004046)
0.4 3.7 GO:0048495 Roundabout binding(GO:0048495)
0.4 1.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 3.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.4 5.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 4.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 1.0 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.3 1.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 1.9 GO:0043495 protein anchor(GO:0043495)
0.2 2.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 1.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 3.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.9 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 3.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.2 2.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.2 3.0 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.9 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.8 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 2.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 2.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 5.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.1 5.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 4.1 GO:0051287 NAD binding(GO:0051287)
0.1 7.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 1.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 4.5 GO:0015293 symporter activity(GO:0015293)
0.0 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 5.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 9.7 GO:0051015 actin filament binding(GO:0051015)
0.0 6.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 10.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)
0.0 1.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 2.2 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0048185 activin binding(GO:0048185)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 5.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 0.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks