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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for Ada

Z-value: 0.63

Transcription factors associated with Ada

Gene Symbol Gene ID Gene Info
ada
ada Ada DNA-binding transcriptional dual regulator / DNA repair protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ada-0.686.2e-02Click!

Activity profile of Ada motif

Sorted Z-values of Ada motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
aidB 3.83
aidB
isovaleryl-CoA dehydrogenase and DNA-binding transcriptional repressor
alkA 1.95
alkA
3-methyl-adenine DNA glycosylase II, inducible

Network of associatons between targets according to the STRING database.

First level regulatory network of Ada

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0006284 base-excision repair(GO:0006284)
0.0 3.3 GO:1903507 negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.2 3.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)