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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for AraC

Z-value: 0.72

Transcription factors associated with AraC

Gene Symbol Gene ID Gene Info
araC
araC AraC DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
araC-0.772.7e-02Click!

Activity profile of AraC motif

Sorted Z-values of AraC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
araJ 2.94
araJ
putative transport protein, major facilitator superfamily
araBAD 2.72
araB
araA
araD
L-ribulokinase
L-arabinose isomerase
L-ribulose 5-phosphate 4-epimerase
araE 2.58
araE
arabinose:H+ symporter
araE-ygeA 1.57
ygeA
araE
predicted racemase
arabinose:H+ symporter
araFGH 0.75
araF
araG
araH
arabinose ABC transporter - periplasmic binding protein
arabinose ABC transporter - ATP binding subunit
arabinose ABC transporter - membrane subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of AraC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0042882 L-arabinose transport(GO:0042882)
0.9 2.7 GO:0019324 L-lyxose metabolic process(GO:0019324)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)
0.0 4.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.9 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0015147 L-arabinose transmembrane transporter activity(GO:0015147)
0.9 2.7 GO:0008742 L-ribulose-phosphate 4-epimerase activity(GO:0008742)