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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for BaeR

Z-value: 0.64

Transcription factors associated with BaeR

Gene Symbol Gene ID Gene Info
baeR
baeR BaeR transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
baeR0.482.3e-01Click!

Activity profile of BaeR motif

Sorted Z-values of BaeR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
spy 2.26
spy
ATP-independent periplasmic chaperone
acrD 1.61
acrD
AcrAD-TolC multidrug efflux pump - permease subunit
mdtABCD-baeSR 1.59
baeR
baeS
mdtC
mdtB
mdtA
mdtD
BaeR transcriptional activator
BaeS sensory histidine kinase
MdtABC-TolC multidrug efflux pump - membrane subunit
MdtABC-TolC multidrug efflux pump - membrane subunit
MdtABC-TolC multidrug efflux pump - putative membrane fusion protein
putative transport protein, major facilitator superfamily (MFS)

Network of associatons between targets according to the STRING database.

First level regulatory network of BaeR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0048583 regulation of response to stimulus(GO:0048583)
0.2 1.6 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 2.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 2.3 GO:0051082 unfolded protein binding(GO:0051082)