Project

GSE55662: Plasticity of transcriptional regulation under antibiotic stress

Navigation
Downloads

Results for CpxR

Z-value: 0.41

Transcription factors associated with CpxR

Gene Symbol Gene ID Gene Info
cpxR
cpxR CpxR transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cpxR0.892.9e-03Click!

Activity profile of CpxR motif

Sorted Z-values of CpxR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
cyaR 2.03
cyaR
CyaR
bamE 1.63
bamE
Outer Membrane Protein Assembly Complex - BamE subunit
yccA 1.53
yccA
putative carrier/transport protein; substrate or modulator of FtsH-mediated proteolysis
ompF 1.14
ompF
outer membrane porin F
degP 0.92
degP
serine protease Do
ompC 0.84
ompC
outer membrane protein C
spy 0.82
spy
ATP-independent periplasmic chaperone
rpoE-rseABC 0.72
rpoE
rseB
rseC
rseA
RNA polymerase, sigma 24 (sigma E) factor
rseB
protein RseC
anti-sigma factor
skp-lpxD-fabZ-lpxA 0.66
lpxA
lpxD
skp
fabZ
UDP-N-acetylglucosamine acyltransferase
UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase
periplasmic chaperone
3-hydroxy-acyl-[acyl-carrier-protein] dehydratase
cpxRA 0.65
cpxA
cpxR
CpxA sensory histidine kinase
CpxR transcriptional dual regulator
dsbC 0.57
dsbC
protein disulfide isomerase/protein disulfide oxidoreductase - DsbCreduced
ppiD 0.44
ppiD
periplasmic folding chaperone
cpxPQ 0.43
cpxQ
cpxP
CpxQ small regulatory RNA
CpxP
yqaE-kbp 0.25
kbp
yqaE
K+ binding protein
predicted membrane protein
yqaE 0.19
yqaE
predicted membrane protein
yebE 0.17
yebE
conserved inner membrane protein
aroG 0.12
aroG
2-dehydro-3-deoxyphosphoheptonate aldolase
yidQ 0.05
yidQ
conserved outer membrane protein
rpoH 0.02
rpoH
RNA polymerase, sigma 32 (sigma H) factor

Network of associatons between targets according to the STRING database.

First level regulatory network of CpxR

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0051205 protein insertion into membrane(GO:0051205)
0.3 2.0 GO:0030162 regulation of proteolysis(GO:0030162)
0.2 0.8 GO:0015748 organophosphate ester transport(GO:0015748)
0.2 0.9 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 1.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.1 GO:0034220 ion transmembrane transport(GO:0034220)
0.0 0.7 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.2 GO:0010038 response to metal ion(GO:0010038)
0.0 0.7 GO:0009314 response to radiation(GO:0009314)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:0045203 integral component of cell outer membrane(GO:0045203)
0.3 1.1 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0071575 integral component of external side of plasma membrane(GO:0071575)
0.0 1.3 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0022885 bacteriocin transmembrane transporter activity(GO:0022885) colicin transmembrane transporter activity(GO:0042912)
0.2 0.7 GO:0045152 antisigma factor binding(GO:0045152)
0.2 0.7 GO:0019171 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity(GO:0008693) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity(GO:0019171) 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity(GO:0047451)
0.1 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity(GO:0003849)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID CMYB PATHWAY C-MYB transcription factor network