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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for DnaA
Z-value: 1.13
Transcription factors associated with DnaA
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
diaA
|
diaA | DnaA initiator-associating factor for replication initiation |
Activity profile of DnaA motif
Sorted Z-values of DnaA motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| nrdAB-yfaE | 4.96 |
nrdA
nrdB
yfaE
|
ribonucleoside diphosphate reductase 1, α subunit ribonucleoside diphosphate reductase 1, β subunit, ferritin-like 2Fe-2S cluster-containing protein involved in diferric-tyrosyl radical cofactor maintenance |
|
| dnaAN-recF | 4.44 |
dnaA
recF
dnaN
|
chromosomal replication initiator protein DnaA; DNA-binding transcriptional dual regulator ssDNA and dsDNA binding, ATP binding DNA polymerase III, β subunit |
|
| rpoH | 3.60 |
rpoH
|
RNA polymerase, sigma 32 (sigma H) factor |
|
| polA | 2.27 |
polA
|
DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease |
|
| guaBA | 0.82 |
guaB
guaA
|
IMP dehydrogenase GMP synthetase |
Network of associatons between targets according to the STRING database.
First level regulatory network of DnaA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 4.4 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) DNA biosynthetic process(GO:0071897) |
| 0.8 | 5.0 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.7 | 3.6 | GO:0001121 | transcription from bacterial-type RNA polymerase promoter(GO:0001121) |
| 0.6 | 2.3 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.3 | 0.8 | GO:1901070 | GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037) GTP metabolic process(GO:0046039) guanosine-containing compound biosynthetic process(GO:1901070) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.0 | GO:1990204 | oxidoreductase complex(GO:1990204) |
| 0.0 | 8.0 | GO:0005886 | plasma membrane(GO:0005886) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.0 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.8 | 2.3 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.7 | 3.6 | GO:0000996 | transcription factor activity, core RNA polymerase binding(GO:0000990) core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) sigma factor activity(GO:0016987) |
| 0.2 | 0.8 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.1 | 4.4 | GO:1990837 | sequence-specific double-stranded DNA binding(GO:1990837) |