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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for FadR

Z-value: 1.27

Transcription factors associated with FadR

Gene Symbol Gene ID Gene Info
fadR
fadR FadR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fadR0.772.4e-02Click!

Activity profile of FadR motif

Sorted Z-values of FadR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
uspA 8.90
uspA
universal stress global stress response regulator
fabHDG 8.58
fabD
fabG
fabH
malonyl-CoA-ACP transacylase
3-oxoacyl-[acyl-carrier-protein] reductase subunit
β-ketoacyl-ACP synthase III
fabI 8.00
fabI
enoyl-[acyl-carrier-protein] reductase subunit
fabB 6.97
fabB
β-ketoacyl-ACP synthase I
accA 5.61
accA
acetyl-CoA carboxyltransferase, α subunit
accD 5.36
accD
acetyl-CoA carboxyltransferase, β subunit
fabA 2.19
fabA
β-hydroxyacyl-ACP dehydratase/isomerase
fadL 1.65
fadL
long-chain fatty acid outer membrane porin; bacteriophage T2 receptor
accBC 0.42
accC
accB
biotin carboxylase
biotin carboxyl carrier protein

Network of associatons between targets according to the STRING database.

First level regulatory network of FadR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.6 GO:0030497 fatty acid elongation(GO:0030497)
1.4 19.9 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 1.6 GO:0006869 lipid transport(GO:0006869)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.0 GO:1990234 transferase complex(GO:1990234)
0.0 1.6 GO:0009279 cell outer membrane(GO:0009279)
0.0 12.9 GO:0005829 cytosol(GO:0005829)
0.0 4.9 GO:0016020 membrane(GO:0016020)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.5 GO:0004312 fatty acid synthase activity(GO:0004312)
0.7 2.2 GO:0047451 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity(GO:0008693) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity(GO:0019171) 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity(GO:0047451)
0.5 1.6 GO:0099600 ion channel activity(GO:0005216) gated channel activity(GO:0022836) transmembrane receptor activity(GO:0099600)
0.3 5.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 14.5 GO:0042802 identical protein binding(GO:0042802)
0.0 0.4 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)