Project

GSE55662: Plasticity of transcriptional regulation under antibiotic stress

Navigation
Downloads

Results for GadX

Z-value: 1.22

Transcription factors associated with GadX

Gene Symbol Gene ID Gene Info
gadX
gadX GadX DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gadX-0.591.2e-01Click!
gadW-0.324.5e-01Click!

Activity profile of GadX motif

Sorted Z-values of GadX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
uspE 6.72
uspE
universal stress protein with a role cellular motility
rpoS 5.22
rpoS
RNA polymerase, sigma S (sigma 38) factor
gadE-mdtEF 5.10
mdtF
mdtE
gadE
MdtEF-TolC multidrug efflux pump - permease subunit
MdtEF-TolC multidrug efflux pump - membrane fusion protein
GadE DNA-binding transcriptional activator
hdeAB-yhiD 3.59
yhiD
hdeB
hdeA
inner membrane protein YhiD
HdeB monomer
HdeA monomer, chaperone active form
gadY 3.31
gadY
GadY
btuB-murI 2.90
murI
btuB
glutamate racemase
vitamin B12 / E colicin / bacteriophage BF23 outer membrane porin BtuB
hdeD 2.74
hdeD
acid-resistance membrane protein
lon 2.13
lon
DNA-binding, ATP-dependent protease La
hns 2.07
hns
H-NS DNA-binding transcriptional dual regulator
cadBA 1.99
cadA
cadB
lysine decarboxylase 1
lysine:cadaverine antiporter
gadE 1.68
gadE
GadE DNA-binding transcriptional activator
asnB 0.54
asnB
asparagine synthetase B
slp-dctR 0.47
slp
dctR
starvation lipoprotein
predicted DNA-binding transcriptional regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of GadX

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
1.1 5.6 GO:0071468 cellular response to acidic pH(GO:0071468)
1.0 5.2 GO:0001121 transcription from bacterial-type RNA polymerase promoter(GO:0001121)
0.7 2.9 GO:0015889 cobalamin transport(GO:0015889)
0.6 5.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.4 2.1 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.2 0.5 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 0.5 GO:0043471 regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.6 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)
0.0 7.3 GO:0005737 cytoplasm(GO:0005737)
0.0 2.8 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.5 GO:0019867 outer membrane(GO:0019867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0001000 bacterial-type RNA polymerase core enzyme binding(GO:0001000)
1.2 3.6 GO:0051087 chaperone binding(GO:0051087)
1.0 2.9 GO:0047661 racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.5 2.0 GO:0015491 L-lysine transmembrane transporter activity(GO:0015189) cation:cation antiporter activity(GO:0015491)
0.5 5.1 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.4 2.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 2.1 GO:0003681 bent DNA binding(GO:0003681)
0.1 0.5 GO:0016884 ammonia ligase activity(GO:0016211) carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)