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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for GalS

Z-value: 0.33

Transcription factors associated with GalS

Gene Symbol Gene ID Gene Info
galS
galS GalS DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
galS0.334.2e-01Click!

Activity profile of GalS motif

Sorted Z-values of GalS motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
mglBAC 0.90
mglA
mglB
mglC
D-galactose / D-galactoside ABC transporter - ATP binding subunit
D-galactose / D-galactoside ABC transporter - periplasmic binding protein
D-galactose / D-galactoside ABC transporter - membrane subunit
galE 0.76
galE
UDP-glucose 4-epimerase
galET 0.75
galT
galE
galactose-1-phosphate uridylyltransferase
UDP-glucose 4-epimerase
galETK 0.64
galT
galE
galK
galactose-1-phosphate uridylyltransferase
UDP-glucose 4-epimerase
galactokinase
galR 0.41
galR
GalR DNA-binding transcriptional dual regulator
galETKM 0.36
galT
galE
galM
galK
galactose-1-phosphate uridylyltransferase
UDP-glucose 4-epimerase
galactose-1-epimerase
galactokinase

Network of associatons between targets according to the STRING database.

First level regulatory network of GalS

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.3 0.9 GO:0015765 methylgalactoside transport(GO:0015765)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 GO:1904949 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.3 0.9 GO:0015592 methylgalactoside transmembrane transporter activity(GO:0015592)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates