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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for GntR

Z-value: 0.99

Transcription factors associated with GntR

Gene Symbol Gene ID Gene Info
gntR
gntR GntR DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gntR-0.866.2e-03Click!

Activity profile of GntR motif

Sorted Z-values of GntR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
gntT 6.73
gntT
gluconate transporter GntT
idnK 3.56
idnK
D-gluconate kinase, thermosensitive
gntKU 2.01
gntK
gntU
D-gluconate kinase, thermostable
gluconate transporter GntU
gntK 1.71
gntK
D-gluconate kinase, thermostable
idnDOTR 1.52
idnD
idnO
idnR
idnT
L-idonate 5-dehydrogenase
5-keto-D-gluconate 5-reductase
IdnR transcriptional regulator
L-idonate / 5-ketogluconate / gluconate transporter IdnT
edd-eda 0.84
eda
edd
multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase
phosphogluconate dehydratase

Network of associatons between targets according to the STRING database.

First level regulatory network of GntR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.1 GO:0019521 D-gluconate metabolic process(GO:0019521) D-gluconate catabolic process(GO:0046177)
0.8 1.5 GO:0042873 aldonate transport(GO:0042873)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 10.3 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0046316 gluconokinase activity(GO:0046316)
2.1 8.3 GO:0015128 gluconate transmembrane transporter activity(GO:0015128) aldonate transmembrane transporter activity(GO:0042879)
0.1 0.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins