ISMARA results: HU

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for HU

Z-value: 1.42

Transcription factors associated with HU

Gene Symbol	Gene ID	Gene Info
hupA RegulonDB EcoCyc	hupA	DNA-binding protein HU-alpha
hupB RegulonDB EcoCyc	hupB	DNA-binding protein HU-beta

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
hupA		0.91	1.7e-03	Click!
hupB		0.91	1.7e-03	Click!

Activity profile of HU motif

Sorted Z-values of HU motif

Top targets:

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Promoter	Log-likelihood	Gene	Gene Info
seqA-pgm Show fit	8.85	seqA RegulonDB EcoCyc Show fit pgm RegulonDB EcoCyc Show fit	SeqA, negative modulator of initiation of replication phosphoglucomutase
galETK Show fit	8.55	galT RegulonDB EcoCyc Show fit galE RegulonDB EcoCyc Show fit galK RegulonDB EcoCyc Show fit	galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase galactokinase
galE Show fit	7.38	galE RegulonDB EcoCyc Show fit	UDP-glucose 4-epimerase
micF Show fit	6.72	micF RegulonDB EcoCyc Show fit	MicF
galETKM Show fit	6.39	galT RegulonDB EcoCyc Show fit galE RegulonDB EcoCyc Show fit galM RegulonDB EcoCyc Show fit galK RegulonDB EcoCyc Show fit	galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase galactose-1-epimerase galactokinase
galET Show fit	5.46	galT RegulonDB EcoCyc Show fit galE RegulonDB EcoCyc Show fit	galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase
mtr Show fit	0.26	mtr RegulonDB EcoCyc Show fit	tryptohan / indole:H+ symporter Mtr

Showing 1 to 7 of 7 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of HU

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
7.3	36.6	GO:0006012	galactose metabolic process(GO:0006012) galactose catabolic process(GO:0019388)
0.1	0.3	GO:0015827	tryptophan transport(GO:0015827)

Showing 1 to 2 of 2 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	27.8	GO:0005829	cytosol(GO:0005829)
1.1	8.8	GO:0032993	protein-DNA complex(GO:0032993)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
6.9	27.8	GO:0003978	UDP-glucose 4-epimerase activity(GO:0003978)
1.8	8.8	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1	0.3	GO:0015196	L-tryptophan transmembrane transporter activity(GO:0015196)

Showing 1 to 3 of 3 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.8	27.8	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates

Showing 1 to 1 of 1 entries

Results for HU

Z-value: 1.42

Transcription factors associated with HU

Activity-expression correlation:

Activity profile of HU motif

Sorted Z-values of HU motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of HU

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: