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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for MarR

Z-value: 0.49

Transcription factors associated with MarR

Gene Symbol Gene ID Gene Info
marR
marR MarR DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
marA-0.482.3e-01Click!
marR-0.482.3e-01Click!

Activity profile of MarR motif

Sorted Z-values of MarR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
marRAB 3.78
marB
marA
marR
multiple antibiotic resistance protein
MarA DNA-binding transcriptional dual regulator
MarR DNA-binding transcriptional repressor

Network of associatons between targets according to the STRING database.

First level regulatory network of MarR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 GO:0001067 regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)