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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for MraZ

Z-value: 0.15

Transcription factors associated with MraZ

Gene Symbol Gene ID Gene Info
mraZ
mraZ MraZ DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mraZ0.147.3e-01Click!

Activity profile of MraZ motif

Sorted Z-values of MraZ motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
mioC 0.30
mioC
flavoprotein involved in biotin synthesis
mraZ-rsmH-ftsLI-murEF-mraY-murD-ftsW-murGC-ddlB-ftsQAZ-lpxC 0.00
murC
mraZ
ftsA
mraY
rsmH
ftsL
murD
murE
ftsI
murG
ftsW
murF
ftsQ
lpxC
ddlB
ftsZ
UDP-N-acetylmuramate-alanine ligase
MraZ DNA-binding transcriptional repressor
essential cell division protein FtsA
phospho-N-acetylmuramoyl-pentapeptide transferase
16S rRNA m4C1402 methyltransferase
essential cell division protein FtsL
UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase
essential cell division protein FtsI; penicillin-binding protein 3
N-acetylglucosaminyl transferase
essential cell division protein FtsW; lipid II flippase
D-alanyl-D-alanine-adding enzyme
essential cell division protein FtsQ
UDP-3-O-acyl-N-acetylglucosamine deacetylase
D-alanine-D-alanine ligase B
essential cell division protein FtsZ

Network of associatons between targets according to the STRING database.

First level regulatory network of MraZ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0006768 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0010181 FMN binding(GO:0010181)