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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for NanR

Z-value: 1.34

Transcription factors associated with NanR

Gene Symbol Gene ID Gene Info
nanR
nanR NanR DNA-binding transcriptional dual regulator

Activity profile of NanR motif

Sorted Z-values of NanR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
nanCMS 7.18
nanC
nanM
nanS
N-acetylneuraminic acid outer membrane channel
N-acetylneuraminate mutarotase
probable 9-O-acetyl-N-acetylneuraminate esterase
nanCM 7.05
nanC
nanM
N-acetylneuraminic acid outer membrane channel
N-acetylneuraminate mutarotase
yjhBC 5.56
yjhC
yjhB
KpLE2 phage-like element; predicted oxidoreductase
putative transport protein, major facilitator superfamily
nanATEK-yhcH 3.89
nanA
nanK
nanE
nanT
yhcH
N-acetylneuraminate lyase
N-acetylmannosamine kinase
predicted N-acetylmannosamine-6-phosphate epimerase
N-acetylneuraminate:H+ symporter
conserved protein
nanA 1.32
nanA
N-acetylneuraminate lyase

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054) N-acetylneuraminate catabolic process(GO:0019262)
1.3 14.2 GO:0015772 oligosaccharide transport(GO:0015772)
0.9 5.6 GO:0015992 hydrogen transport(GO:0006818) proton transport(GO:0015992)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 14.2 GO:0045203 integral component of cell outer membrane(GO:0045203)
0.0 9.4 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 18.1 GO:0015136 sialic acid transmembrane transporter activity(GO:0015136)
0.2 1.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 5.6 GO:0046943 organic acid transmembrane transporter activity(GO:0005342) carboxylic acid transmembrane transporter activity(GO:0046943)