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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for OxyR

Z-value: 0.99

Transcription factors associated with OxyR

Gene Symbol Gene ID Gene Info
oxyR
oxyR OxyR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
oxyR0.884.0e-03Click!

Activity profile of OxyR motif

Sorted Z-values of OxyR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
ahpCF 8.95
ahpF
ahpC
alkyl hydroperoxide reductase, AhpF component
alkyl hydroperoxide reductase, AhpC component
dps 3.85
dps
stationary phase nucleoid protein that sequesters iron and protects DNA from damage
hcp-hcr 3.70
hcr
hcp
NADH oxidoreductase
hybrid-cluster protein
uxuAB 2.31
uxuA
uxuB
D-mannonate dehydratase
D-mannonate oxidoreductase
ychF 1.93
ychF
ribosome-binding ATPase, inhibitor of catalase activity
katG 1.86
katG
hydroperoxidase I
oxyR 1.65
oxyR
OxyR DNA-binding transcriptional dual regulator
gntP 1.44
gntP
gluconate / fructuronate transporter GntP
ybjC-nfsA-rimK-ybjN 0.81
nfsA
ybjN
ybjC
rimK
NADPH nitroreductase NfsA
predicted oxidoreductase
predicted inner membrane protein
ribosomal protein S6 modification protein
uof-fur 0.24
fur
uof
Fur transcriptional dual regulator
RyhB-regulated fur leader peptide
oxyS 0.10
oxyS
OxyS

Network of associatons between targets according to the STRING database.

First level regulatory network of OxyR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0009970 cellular response to sulfate starvation(GO:0009970)
1.2 3.7 GO:0046209 nitric oxide metabolic process(GO:0046209) nitric oxide catabolic process(GO:0046210)
0.8 2.3 GO:0006063 uronic acid metabolic process(GO:0006063)
0.5 1.4 GO:0042873 aldonate transport(GO:0042873)
0.4 1.9 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.3 0.8 GO:1902116 negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209)
0.1 3.9 GO:0042594 response to starvation(GO:0042594)
0.1 1.6 GO:2000142 regulation of DNA-templated transcription, initiation(GO:2000142)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0005576 extracellular region(GO:0005576)
0.4 8.9 GO:1990204 oxidoreductase complex(GO:1990204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0070402 NADPH binding(GO:0070402)
0.6 1.9 GO:0004096 catalase activity(GO:0004096)
0.3 3.7 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 1.4 GO:0042879 gluconate transmembrane transporter activity(GO:0015128) aldonate transmembrane transporter activity(GO:0042879)
0.3 0.8 GO:0034567 chromate reductase activity(GO:0034567)
0.2 1.9 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.1 5.3 GO:0005506 iron ion binding(GO:0005506)
0.1 1.6 GO:0001131 transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001131)