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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for Rob
Z-value: 0.60
Transcription factors associated with Rob
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| rob | 0.78 | 2.1e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| sodA Show fit | 3.18 |
superoxide dismutase (Mn) |
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| tolC-ygiABC Show fit | 1.91 |
predicted enzyme with ATPase activity conserved outer membrane protein predicted protein TolC outer membrane channel |
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| rob Show fit | 1.46 |
Rob DNA-binding transcriptional dual regulator |
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| zwf Show fit | 1.45 |
glucose-6-phosphate dehydrogenase (NADP+) |
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| ldtB Show fit | 1.38 |
L,D-transpeptidase YbiS |
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| micF Show fit | 1.23 |
MicF |
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| fumC Show fit | 0.80 |
fumarase C |
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| acrAB Show fit | 0.73 |
AcrAB-TolC multidrug efflux pump - permease subunit AcrAB-TolC multidrug efflux pump - membrane fusion protein |
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| ybjC-nfsA-rimK-ybjN Show fit | 0.57 |
NADPH nitroreductase NfsA predicted oxidoreductase predicted inner membrane protein ribosomal protein S6 modification protein |
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| nfo Show fit | 0.55 |
endonuclease IV |
Network of associatons between targets according to the STRING database.
First level regulatory network of Rob
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.2 | GO:0006801 | response to superoxide(GO:0000303) superoxide metabolic process(GO:0006801) |
| 0.3 | 1.9 | GO:0015891 | siderophore transport(GO:0015891) |
| 0.5 | 1.5 | GO:0009372 | quorum sensing(GO:0009372) |
| 0.5 | 1.4 | GO:0043164 | Gram-negative-bacterium-type cell wall biogenesis(GO:0043164) |
| 0.3 | 0.8 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 0.7 | GO:0006855 | drug transmembrane transport(GO:0006855) |
| 0.2 | 0.6 | GO:1900232 | negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209) |
| 0.1 | 0.6 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 0.3 | GO:0046263 | trinitrotoluene metabolic process(GO:0018973) 2,4,6-trinitrotoluene metabolic process(GO:0018974) nitrotoluene metabolic process(GO:0019326) 2,4,6-trinitrotoluene catabolic process(GO:0046256) trinitrotoluene catabolic process(GO:0046260) nitrotoluene catabolic process(GO:0046263) toluene-containing compound metabolic process(GO:0072490) toluene-containing compound catabolic process(GO:0072491) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.3 | GO:0005829 | cytosol(GO:0005829) |
| 0.1 | 2.6 | GO:1990351 | transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.2 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.3 | 1.9 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.0 | 1.5 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
| 0.0 | 1.5 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.5 | 1.4 | GO:0016807 | cysteine-type peptidase activity(GO:0008234) cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) peptidoglycan L,D-transpeptidase activity(GO:0071972) |
| 0.2 | 0.8 | GO:0004333 | fumarate hydratase activity(GO:0004333) |
| 0.2 | 0.7 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.2 | 0.6 | GO:0034567 | chromate reductase activity(GO:0034567) |
| 0.1 | 0.6 | GO:0008081 | endodeoxyribonuclease activity(GO:0004520) phosphoric diester hydrolase activity(GO:0008081) |
| 0.0 | 0.3 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |