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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for RutR

Z-value: 1.49

Transcription factors associated with RutR

Gene Symbol Gene ID Gene Info
rutR
rutR RutR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rutR-0.285.1e-01Click!

Activity profile of RutR motif

Sorted Z-values of RutR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
gadX 7.26
gadX
GadX DNA-binding transcriptional dual regulator
carAB 6.61
carB
carA
carbamoyl phosphate synthetase, β chain
carbamoyl phosphate synthetase, α chain
gadXW 6.04
gadW
gadX
GadW DNA-binding transcriptional dual regulator
GadX DNA-binding transcriptional dual regulator
fepB 3.77
fepB
ferric enterobactin ABC transporter - periplasmic binding protein
pdeR 1.83
pdeR
cyclic di-GMP phosphodiesterase
rutR 1.56
rutR
RutR DNA-binding transcriptional dual regulator
nemRA 1.33
nemA
nemR
N-ethylmaleimide reductase, FMN-linked
NemR DNA-binding transcriptional repressor
rutABCDEFG 1.29
rutC
rutB
rutA
rutG
rutF
rutE
rutD
predicted aminoacrylate peracid reductase
peroxyureidoacrylate / ureidoacrylate amido hydrolase
pyrimidine oxygenase
uracil:H+ symporter RutG
flavin reductase
predicted malonic semialdehyde reductase
predicted aminoacrylate hydrolase

Network of associatons between targets according to the STRING database.

First level regulatory network of RutR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.6 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.9 3.8 GO:0015685 ferric-enterobactin transport(GO:0015685)
0.4 1.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) pyrimidine nucleobase transport(GO:0015855)
0.2 14.9 GO:0051254 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)
0.1 1.8 GO:0043086 negative regulation of catalytic activity(GO:0043086)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.6 GO:1902494 catalytic complex(GO:1902494)
0.1 3.8 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.5 13.3 GO:0001140 transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140)
0.4 1.3 GO:0005350 monooxygenase activity(GO:0004497) pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.4 1.8 GO:0071111 cyclic-guanylate-specific phosphodiesterase activity(GO:0071111)
0.0 1.0 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)