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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for YefM

Z-value: 0.31

Transcription factors associated with YefM

Gene Symbol Gene ID Gene Info
yefM
yefM YefM antitoxin of the YoeB-YefM toxin-antitoxin pair and DNA binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
yefM0.992.9e-06Click!

Activity profile of YefM motif

Sorted Z-values of YefM motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
yefM-yoeB 1.35
yefM
yoeB
YefM antitoxin of the YoeB-YefM toxin-antitoxin pair and DNA binding transcriptional repressor
toxin of the YoeB-YefM toxin-antitoxin pair

Network of associatons between targets according to the STRING database.

First level regulatory network of YefM

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0045947 regulation of translational initiation(GO:0006446) negative regulation of translational initiation(GO:0045947) RNA phosphodiester bond hydrolysis(GO:0090501)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0016892 toxic substance binding(GO:0015643) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)