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GSE67402: E.coli regulatory changes under long-term starvation

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Results for AraC

Z-value: 1.99

Transcription factors associated with AraC

Gene Symbol Gene ID Gene Info
araC
araC AraC DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
araC0.115.7e-01Click!

Activity profile of AraC motif

Sorted Z-values of AraC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
araBAD 32.43
araB
araA
araD
L-ribulokinase
L-arabinose isomerase
L-ribulose 5-phosphate 4-epimerase
araC 25.74
araC
AraC DNA-binding transcriptional dual regulator
ydeNM 24.49
ydeM
ydeN
predicted anaerobic sulfatase maturation enzyme
putative sulfatase
araE 20.09
araE
arabinose:H+ symporter
araFGH 13.40
araF
araG
araH
arabinose ABC transporter - periplasmic binding protein
arabinose ABC transporter - ATP binding subunit
arabinose ABC transporter - membrane subunit
araJ 13.27
araJ
putative transport protein, major facilitator superfamily
xylAB 13.03
xylA
xylB
xylose isomerase
xylulokinase
araE-ygeA 11.57
ygeA
araE
predicted racemase
arabinose:H+ symporter

Network of associatons between targets according to the STRING database.

First level regulatory network of AraC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
15.0 45.1 GO:0042882 L-arabinose transport(GO:0042882)
14.5 58.2 GO:0019568 arabinose metabolic process(GO:0019566) arabinose catabolic process(GO:0019568)
1.3 13.0 GO:0019323 pentose catabolic process(GO:0019323)
1.1 24.5 GO:0051604 protein maturation(GO:0051604)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 13.4 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)
0.3 24.5 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)
0.2 31.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 13.3 GO:0005886 plasma membrane(GO:0005886)
0.1 58.2 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
15.0 45.1 GO:0015147 L-arabinose transmembrane transporter activity(GO:0015147)
10.8 32.4 GO:0008742 L-ribulose-phosphate 4-epimerase activity(GO:0008742)
1.0 13.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 25.7 GO:0005515 protein binding(GO:0005515)