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GSE67402: E.coli regulatory changes under long-term starvation

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Results for BasR

Z-value: 0.71

Transcription factors associated with BasR

Gene Symbol Gene ID Gene Info
basR
basR BasR transcriptional regulator

Activity profile of BasR motif

Sorted Z-values of BasR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
tomB-hha 11.29
tomB
hha
protein that modulates Hha toxicity
haemolysin expression modulating protein
cspI 5.30
cspI
Qin prophage; cold shock protein
dgkA 3.05
dgkA
diacylglycerol kinase
qseBC 2.81
qseC
qseB
QseC sensory histidine kinase
QseB transcriptional activator
putA 2.23
putA
fused PutA transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase
csgDEFG 1.26
csgG
csgF
csgE
csgD
curli secretion channel
curli assembly component
curli transport specificity factor
CsgD DNA-binding transcriptional dual regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of BasR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.6 GO:0044010 single-species biofilm formation(GO:0044010)
0.4 2.2 GO:0009065 glutamine family amino acid catabolic process(GO:0009065)
0.4 3.1 GO:0046474 glycerophospholipid metabolic process(GO:0006650) glycerolipid biosynthetic process(GO:0045017) glycerophospholipid biosynthetic process(GO:0046474) glycerolipid metabolic process(GO:0046486)
0.4 5.3 GO:0009409 response to cold(GO:0009409)
0.1 2.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0031246 intrinsic component of periplasmic side of cell outer membrane(GO:0031246)
0.1 2.2 GO:0098562 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.0 16.6 GO:0005829 cytosol(GO:0005829)
0.0 5.9 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0001141 transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001141) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 2.8 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.1 1.3 GO:0000987 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 11.3 GO:0003677 DNA binding(GO:0003677)
0.1 3.1 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 REACTOME HEMOSTASIS Genes involved in Hemostasis