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GSE67402: E.coli regulatory changes under long-term starvation

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Results for DcuR

Z-value: 1.16

Transcription factors associated with DcuR

Gene Symbol Gene ID Gene Info
dcuR
dcuR DcuR transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dcuR-0.806.1e-07Click!

Activity profile of DcuR motif

Sorted Z-values of DcuR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
dctA 25.32
dctA
C4 dicarboxylate / orotate:H+ symporter
dcuB-fumB 16.55
fumB
dcuB
fumarase B
dicarboxylate transporter DcuB
frdABCD 11.93
frdA
frdB
frdC
frdD
fumarate reductase flavoprotein
fumarate reductase iron-sulfur protein
fumarate reductase membrane protein
fumarate reductase membrane protein
dpiBA 4.39
dpiB
dpiA
DpiB sensory histidine kinase
DpiA transcriptional dual regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of DcuR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 41.9 GO:0015740 dicarboxylic acid transport(GO:0006835) C4-dicarboxylate transport(GO:0015740)
2.0 11.9 GO:0006113 fermentation(GO:0006113)
1.5 4.4 GO:0071310 cellular response to organic substance(GO:0071310)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 11.9 GO:0045274 respiratory chain complex II(GO:0045273) plasma membrane respiratory chain complex II(GO:0045274)
0.2 46.3 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 41.9 GO:0015141 dicarboxylic acid transmembrane transporter activity(GO:0005310) fumarate transmembrane transporter activity(GO:0015138) succinate transmembrane transporter activity(GO:0015141) C4-dicarboxylate transmembrane transporter activity(GO:0015556)
4.0 11.9 GO:0016635 succinate dehydrogenase activity(GO:0000104) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.7 4.4 GO:0000156 phosphorelay response regulator activity(GO:0000156)