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GSE67402: E.coli regulatory changes under long-term starvation

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Results for EvgA

Z-value: 1.12

Transcription factors associated with EvgA

Gene Symbol Gene ID Gene Info
evgA
evgA EvgA transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
evgA-0.704.5e-05Click!

Activity profile of EvgA motif

Sorted Z-values of EvgA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
emrKY 17.46
emrY
emrK
EmrKY multidrug efflux pump - membrane subunit
EmrKY-TolC multidrug efflux pump - membrane fusion protein
yfdX-frc-oxc-yfdVE 16.86
frc
yfdE
yfdV
yfdX
oxc
formyl-CoA transferase
acetyl-CoA:oxalate CoA-transferase
putative transport protein, auxin efflux carrier family
predicted protein
oxalyl-CoA decarboxylase
frc 15.68
frc
formyl-CoA transferase
safA-ydeO 10.50
ydeO
safA
YdeO DNA-binding transcriptional dual regulator
two-component system connector protein
yegRZ 5.47
yegR
yegZ
predicted protein
predicted protein fragment
acrD 2.03
acrD
AcrAD-TolC multidrug efflux pump - permease subunit
gadE-mdtEF 1.63
mdtF
mdtE
gadE
MdtEF-TolC multidrug efflux pump - permease subunit
MdtEF-TolC multidrug efflux pump - membrane fusion protein
GadE DNA-binding transcriptional activator
ydeP 0.31
ydeP
acid resistance protein

Network of associatons between targets according to the STRING database.

First level regulatory network of EvgA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.5 GO:0071468 cellular response to acidic pH(GO:0071468)
0.6 19.1 GO:0046677 response to antibiotic(GO:0046677)
0.4 2.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.2 10.5 GO:1902680 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 48.5 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.8 32.5 GO:0008410 CoA-transferase activity(GO:0008410)
0.7 2.0 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 1.6 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.1 10.5 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 17.5 GO:0005215 transporter activity(GO:0005215)