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GSE67402: E.coli regulatory changes under long-term starvation

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Results for ModE

Z-value: 0.72

Transcription factors associated with ModE

Gene Symbol Gene ID Gene Info
modE
modE ModE transcriptional dual regulator

Activity profile of ModE motif

Sorted Z-values of ModE motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
oppABCDF 12.04
oppA
oppC
oppB
oppD
oppF
peptide ABC transporter - periplasmic binding protein
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative membrane subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative ATP binding subunit
murein tripeptide ABC transporter / peptide ABC transporter - putative ATP binding subunit
modABC 4.71
modA
modB
modC
molybdate ABC transporter - periplasmic binding protein
molybdate ABC transporter - membrane subunit
molybdate ABC transporter - ATP binding subunit
hycABCDEFGHI 4.23
hycD
hycE
hycF
hycG
hycA
hycB
hycC
hycH
hycI
hydrogenase 3, membrane subunit
hydrogenase 3, large subunit
formate hydrogenlyase complex iron-sulfur protein
hydrogenase 3 and formate hydrogenlyase complex, HycG subunit
regulator of the transcriptional regulator FhlA
hydrogenase 3, Fe-S subunit
hydrogenase 3, membrane subunit
protein required for maturation of hydrogenase 3
hydrogenase 3 maturation protease
deoCABD 3.37
deoA
deoB
deoC
deoD
thymidine phosphorylase / uracil phosphorylase
phosphopentomutase
deoxyribose-phosphate aldolase
purine nucleoside phosphorylase
napFDAGHBC-ccmABCDEFGH 3.25
napG
napF
napD
napC
ccmH
napA
ccmE
ccmD
ccmG
ccmF
ccmA
ccmC
ccmB
napH
napB
ferredoxin-type protein
ferredoxin-type protein
signal peptide-binding chaperone for NapA
periplasmic nitrate reductase, cytochrome c protein
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmH
large subunit of periplasmic nitrate reductase, molybdoprotein
membrane anchored periplasmic heme chaperone CcmE
ABC complex for formation and release of holoCcmE - membrane subunit CcmD
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmG
holocytochrome c synthetase - CcmF subunit
ABC complex for formation and release of holoCcmE - ATP binding subunit
ABC complex for formation and release of holoCcmE - membrane subunit CcmC
ABC complex for formation and release of holoCcmE - membrane subunit CcmB
ferredoxin-type protein
subunit of periplasmic nitrate reductase, cytochrome c550 protein

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.0 GO:0006857 oligopeptide transport(GO:0006857) oligopeptide transmembrane transport(GO:0035672)
1.6 3.2 GO:0015886 heme transport(GO:0015886)
1.1 3.4 GO:0009264 deoxyribonucleotide catabolic process(GO:0009264)
0.8 4.2 GO:0016485 protein processing(GO:0016485)
0.3 4.7 GO:0015698 inorganic anion transport(GO:0015698)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 16.8 GO:0098533 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 2.6 GO:1990204 oxidoreductase complex(GO:1990204)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.0 GO:0015647 oligopeptide transporter activity(GO:0015198) peptidoglycan transporter activity(GO:0015647) oligopeptide transmembrane transporter activity(GO:0035673)
1.3 8.0 GO:0030151 molybdenum ion binding(GO:0030151)
1.1 3.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.4 4.2 GO:0016151 nickel cation binding(GO:0016151)