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GSE67402: E.coli regulatory changes under long-term starvation

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Results for NarP

Z-value: 1.34

Transcription factors associated with NarP

Gene Symbol Gene ID Gene Info
narP
narP NarP transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
narP-0.634.4e-04Click!

Activity profile of NarP motif

Sorted Z-values of NarP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
ytfE 21.61
ytfE
iron-sulfur cluster repair protein YtfE
fdnGHI 15.37
fdnH
fdnI
fdnG
formate dehydrogenase N, β subunit
formate dehydrogenase N, γ subunit
formate dehydrogenase N, α subunit
yeaR-yoaG 14.05
yoaG
yeaR
predicted protein
conserved protein
napFDAGHBC-ccmABCDEFGH 13.28
napG
napF
napD
napC
ccmH
napA
ccmE
ccmD
ccmG
ccmF
ccmA
ccmC
ccmB
napH
napB
ferredoxin-type protein
ferredoxin-type protein
signal peptide-binding chaperone for NapA
periplasmic nitrate reductase, cytochrome c protein
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmH
large subunit of periplasmic nitrate reductase, molybdoprotein
membrane anchored periplasmic heme chaperone CcmE
ABC complex for formation and release of holoCcmE - membrane subunit CcmD
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmG
holocytochrome c synthetase - CcmF subunit
ABC complex for formation and release of holoCcmE - ATP binding subunit
ABC complex for formation and release of holoCcmE - membrane subunit CcmC
ABC complex for formation and release of holoCcmE - membrane subunit CcmB
ferredoxin-type protein
subunit of periplasmic nitrate reductase, cytochrome c550 protein
hcp-hcr 12.80
hcr
hcp
NADH oxidoreductase
hybrid-cluster protein
ydhYVWXUT 5.97
ydhY
ydhX
ydhW
ydhV
ydhU
ydhT
predicted 4Fe-4S ferredoxin-type protein
predicted 4Fe-4S ferredoxin-type protein
predicted protein
predicted oxidoreductase
predicted cytochrome
conserved protein
norVW 2.86
norW
norV
NADH:flavorubredoxin reductase
flavorubredoxin
hyaABCDEF 2.78
hyaB
hyaC
hyaA
hyaF
hyaD
hyaE
hydrogenase 1, large subunit
hydrogenase 1, b-type cytochrome subunit
hydrogenase 1, small subunit
protein involved in nickel incorporation into hydrogenase 1 proteins
protein involved in processing of HyaA and HyaB proteins
protein involved in quality control of HyaA
ydeP 2.31
ydeP
acid resistance protein

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 21.6 GO:0030091 protein repair(GO:0030091)
5.2 15.7 GO:0046209 nitric oxide metabolic process(GO:0046209) nitric oxide catabolic process(GO:0046210)
4.4 13.3 GO:0051223 heme transport(GO:0015886) regulation of protein localization(GO:0032880) regulation of protein transport(GO:0051223) regulation of establishment of protein localization(GO:0070201)
3.3 13.2 GO:0015942 formate metabolic process(GO:0015942)
0.6 2.8 GO:0016485 fermentation(GO:0006113) protein processing(GO:0016485)
0.3 2.3 GO:0010447 response to acidic pH(GO:0010447)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.4 15.4 GO:0071575 integral component of external side of plasma membrane(GO:0071575)
0.9 2.8 GO:0031237 intrinsic component of external side of plasma membrane(GO:0031233) intrinsic component of periplasmic side of plasma membrane(GO:0031237)
0.1 5.8 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288)
0.0 19.5 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.1 GO:0005048 signal sequence binding(GO:0005048)
3.3 13.2 GO:0030151 molybdenum ion binding(GO:0030151)
1.3 12.8 GO:0016684 peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.6 24.5 GO:0005506 iron ion binding(GO:0005506)