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GSE67402: E.coli regulatory changes under long-term starvation

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Results for Rob

Z-value: 0.59

Transcription factors associated with Rob

Gene Symbol Gene ID Gene Info
rob
rob Rob DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rob0.403.8e-02Click!

Activity profile of Rob motif

Sorted Z-values of Rob motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
tolC-ygiABC 5.12
ygiC
ygiB
ygiA
tolC
predicted enzyme with ATPase activity
conserved outer membrane protein
predicted protein
TolC outer membrane channel
sodA 4.86
sodA
superoxide dismutase (Mn)
ybjC-nfsA-rimK-ybjN 2.83
nfsA
ybjN
ybjC
rimK
NADPH nitroreductase NfsA
predicted oxidoreductase
predicted inner membrane protein
ribosomal protein S6 modification protein
acrAB 2.66
acrB
acrA
AcrAB-TolC multidrug efflux pump - permease subunit
AcrAB-TolC multidrug efflux pump - membrane fusion protein
zwf 2.27
zwf
glucose-6-phosphate dehydrogenase (NADP+)
nfo 1.65
nfo
endonuclease IV
nfsB 1.31
nfsB
NAD(P)H nitroreductase NfsB
ldtB 1.08
ldtB
L,D-transpeptidase YbiS
inaA 0.95
inaA
pH-inducible protein involved in stress response
aslB 0.67
aslB
predicted anaerobic sulfatase maturation enzyme
acnA 0.66
acnA
aconitate hydratase 1
acrZ 0.22
acrZ
small membrane protein that interacts with the AcrAB-TolC multidrug efflux pump

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0000303 response to superoxide(GO:0000303) superoxide metabolic process(GO:0006801)
0.9 2.8 GO:0043687 negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209)
0.9 5.1 GO:0015891 siderophore transport(GO:0015891)
0.8 2.3 GO:0009372 quorum sensing(GO:0009372)
0.4 1.3 GO:0046256 trinitrotoluene metabolic process(GO:0018973) 2,4,6-trinitrotoluene metabolic process(GO:0018974) nitrotoluene metabolic process(GO:0019326) 2,4,6-trinitrotoluene catabolic process(GO:0046256) trinitrotoluene catabolic process(GO:0046260) nitrotoluene catabolic process(GO:0046263) toluene-containing compound metabolic process(GO:0072490) toluene-containing compound catabolic process(GO:0072491)
0.4 1.7 GO:0006284 base-excision repair(GO:0006284)
0.4 1.1 GO:0043164 Gram-negative-bacterium-type cell wall biogenesis(GO:0043164)
0.3 2.7 GO:0006855 drug transmembrane transport(GO:0006855)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.2 GO:0036460 cellular response to cell envelope stress(GO:0036460)
0.0 0.7 GO:0051604 protein maturation(GO:0051604)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.8 GO:1990351 transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351)
0.0 10.1 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.9 2.8 GO:0034567 chromate reductase activity(GO:0034567)
0.9 2.7 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.9 5.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 1.1 GO:0070004 cysteine-type peptidase activity(GO:0008234) cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) peptidoglycan L,D-transpeptidase activity(GO:0071972)
0.2 1.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.2 1.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.3 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0015238 drug transmembrane transporter activity(GO:0015238)