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GSE67402: E.coli regulatory changes under long-term starvation

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Results for TyrR

Z-value: 0.77

Transcription factors associated with TyrR

Gene Symbol Gene ID Gene Info
tyrR
tyrR TyrR DNA-binding transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tyrR0.722.3e-05Click!

Activity profile of TyrR motif

Sorted Z-values of TyrR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
aroF-tyrA 14.03
tyrA
aroF
chorismate mutase / prephenate dehydrogenase
2-dehydro-3-deoxyphosphoheptonate aldolase
aroG 13.86
aroG
2-dehydro-3-deoxyphosphoheptonate aldolase
tyrB 6.50
tyrB
tyrosine aminotransferase
aroL-yaiA-aroM 2.26
yaiA
aroL
aroM
predicted protein
shikimate kinase II
conserved protein
aroP 0.82
aroP
aromatic amino acid:H+ symporter AroP

Network of associatons between targets according to the STRING database.

First level regulatory network of TyrR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.5 GO:0006571 tyrosine metabolic process(GO:0006570) tyrosine biosynthetic process(GO:0006571)
1.5 16.1 GO:0009073 aromatic amino acid family biosynthetic process(GO:0009073)
0.2 0.8 GO:0015823 phenylalanine transport(GO:0015823)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 28.5 GO:0005737 cytoplasm(GO:0005737)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 27.9 GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity(GO:0003849)
0.4 6.5 GO:0008483 transaminase activity(GO:0008483)
0.3 0.8 GO:0009977 proton motive force dependent protein transmembrane transporter activity(GO:0009977) L-phenylalanine transmembrane transporter activity(GO:0015192)
0.0 2.3 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)