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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Irf4

Z-value: 0.33

Motif logo

Transcription factors associated with Irf4

Gene Symbol Gene ID Gene Info
ENSRNOG00000061070 interferon regulatory factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irf4rn6_v1_chr17_-_34905117_34905117-0.553.3e-01Click!

Activity profile of Irf4 motif

Sorted Z-values of Irf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_198008893 0.17 ENSRNOT00000025950
interleukin 27
chr17_+_72429618 0.10 ENSRNOT00000026187
GATA binding protein 3
chr15_-_108898703 0.08 ENSRNOT00000067577
Zic family member 5
chr8_+_55050284 0.07 ENSRNOT00000013242
PIH1 domain containing 2
chr10_-_105412627 0.07 ENSRNOT00000034817
glutamine rich 2
chr15_+_24141651 0.07 ENSRNOT00000082304
galectin 3
chr1_+_220948331 0.07 ENSRNOT00000036185
adaptor-related protein complex 5, beta 1 subunit
chr17_+_47662532 0.05 ENSRNOT00000081314
STARD3 N-terminal like
chr1_-_214252456 0.05 ENSRNOT00000023504
interferon regulatory factor 7
chr9_-_64096265 0.05 ENSRNOT00000013502
tRNA-yW synthesizing protein 5
chr8_-_92942076 0.05 ENSRNOT00000056937
family with sequence similarity 46, member A
chr9_+_18001105 0.05 ENSRNOT00000071814

chr7_+_122700854 0.04 ENSRNOT00000086603
ring-box 1
chr2_-_96032722 0.04 ENSRNOT00000015746
proteasome subunit beta type 6-like
chr2_-_185852759 0.04 ENSRNOT00000049461
mab-21 like 2
chr9_+_84410972 0.04 ENSRNOT00000019724
monoacylglycerol O-acyltransferase 1
chr20_-_50564987 0.04 ENSRNOT00000034485
ENSRNOT00000064466
lin-28 homolog B
chr6_-_135049728 0.04 ENSRNOT00000009556
heat shock protein 90 alpha family class A member 1
chr8_-_55050194 0.04 ENSRNOT00000013197
hypothetical LOC100151767
chr1_+_80056755 0.04 ENSRNOT00000021221
small nuclear ribonucleoprotein D2 polypeptide
chr2_+_58724855 0.04 ENSRNOT00000089609
calcyphosine-like
chr1_+_266333440 0.04 ENSRNOT00000071243
sideroflexin 2
chr1_+_196095214 0.03 ENSRNOT00000080741
similar to ribosomal protein S15a
chrX_+_31984612 0.03 ENSRNOT00000005181
BMX non-receptor tyrosine kinase
chr2_+_95077577 0.03 ENSRNOT00000046368
mitochondrial ribosomal protein S28
chr13_-_102643223 0.03 ENSRNOT00000003155
H2.0-like homeobox
chr8_-_53223804 0.03 ENSRNOT00000008965
5-hydroxytryptamine receptor 3A
chr15_+_105640097 0.03 ENSRNOT00000014300
muscleblind-like splicing regulator 2
chrX_-_105308554 0.03 ENSRNOT00000045556
TATA-box binding protein associated factor 7-like
chr15_+_34256071 0.03 ENSRNOT00000025887
proteasome activator subunit 1
chrM_+_8599 0.03 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr15_+_43905099 0.03 ENSRNOT00000016568
early B-cell factor 2
chr8_+_117307339 0.03 ENSRNOT00000064571
glutamine-rich 1
chr7_-_143353925 0.03 ENSRNOT00000068533
keratin 71
chr2_-_196046311 0.03 ENSRNOT00000028484
proteasome subunit beta 4
chr17_-_32015071 0.03 ENSRNOT00000070876
leukocyte elastase inhibitor A-like
chr10_+_74724549 0.03 ENSRNOT00000009077
testis expressed 14, intercellular bridge forming factor
chr5_-_151898022 0.03 ENSRNOT00000000133
phosphatidylinositol glycan anchor biosynthesis, class V
chr1_-_16687817 0.02 ENSRNOT00000091376
ENSRNOT00000081620
MYB proto-oncogene, transcription factor
chr16_+_2706428 0.02 ENSRNOT00000077117
interleukin 17 receptor D
chr2_-_210991509 0.02 ENSRNOT00000087329
cytochrome b561 family, member D1
chr20_+_25990656 0.02 ENSRNOT00000081254
leucine rich repeat transmembrane neuronal 3
chr2_-_30577218 0.02 ENSRNOT00000024674
occludin
chr13_-_79899479 0.02 ENSRNOT00000035815
similar to hypothetical protein
chr6_+_147315328 0.02 ENSRNOT00000056654
MACC1, MET transcriptional regulator
chr14_+_113530470 0.02 ENSRNOT00000004919
polyribonucleotide nucleotidyltransferase 1
chr9_+_73493027 0.02 ENSRNOT00000074427
ENSRNOT00000089478
unc-80 homolog, NALCN activator
chr5_-_107857320 0.02 ENSRNOT00000008898
cyclin-dependent kinase inhibitor 2B
chr19_-_49448072 0.02 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr1_-_142183884 0.02 ENSRNOT00000016032
FES proto-oncogene, tyrosine kinase
chr13_+_48790951 0.02 ENSRNOT00000090233
ELK4, ETS transcription factor
chr20_-_4698718 0.02 ENSRNOT00000047527
RT1 class I, locus CE7
chr20_-_27682861 0.02 ENSRNOT00000057317
family with sequence similarity 26, member F
chr15_+_18710492 0.02 ENSRNOT00000012532
deoxyribonuclease 1-like 3
chr10_+_34277993 0.02 ENSRNOT00000055872
ENSRNOT00000003343
interferon gamma inducible protein 47
chr18_+_83471342 0.02 ENSRNOT00000019384
neuropilin and tolloid like 1
chr2_-_30576591 0.02 ENSRNOT00000084667
occludin
chr18_-_56728185 0.02 ENSRNOT00000066048
PPARG coactivator 1 beta
chr9_+_64095978 0.02 ENSRNOT00000021533
matrix AAA peptidase interacting protein 1
chr5_-_126782726 0.02 ENSRNOT00000048784
transcription elongation factor A N-terminal and central domain containing 2
chr3_-_52510507 0.02 ENSRNOT00000091259
sodium voltage-gated channel alpha subunit 1
chr7_+_91832988 0.02 ENSRNOT00000006410
solute carrier family 30 member 8
chr20_-_35450513 0.02 ENSRNOT00000087342
mannosidase, alpha, class 1A, member 1
chr6_+_123974798 0.01 ENSRNOT00000075794
potassium two pore domain channel subfamily K member 13
chr1_-_47213749 0.01 ENSRNOT00000024656
dynein light chain Tctex-type 1
chr1_-_40921508 0.01 ENSRNOT00000026433
zinc finger and BTB domain containing 2
chr5_-_33892462 0.01 ENSRNOT00000009334
ATPase H+ transporting V0 subunit D2
chr4_+_112773938 0.01 ENSRNOT00000009321
eva-1 homolog A, regulator of programmed cell death
chr2_+_165076607 0.01 ENSRNOT00000012831
interleukin 12A
chr5_-_59913348 0.01 ENSRNOT00000018164
heterogeneous nuclear ribonucleoprotein K-like
chr5_-_107858104 0.01 ENSRNOT00000092196
cyclin-dependent kinase inhibitor 2B
chr5_+_154077944 0.01 ENSRNOT00000031512
interleukin 22 receptor subunit alpha 1
chr1_+_260289589 0.01 ENSRNOT00000051058
DNA nucleotidylexotransferase
chr11_+_67757928 0.01 ENSRNOT00000039215
deltex E3 ubiquitin ligase 3L
chr15_-_9086282 0.01 ENSRNOT00000008989
thyroid hormone receptor beta
chr3_+_120726906 0.01 ENSRNOT00000051069
BCL2 like 11
chr1_-_201110928 0.01 ENSRNOT00000027721
NSE4 homolog A, SMC5-SMC6 complex component
chr20_-_4542073 0.01 ENSRNOT00000000477
complement factor B
chr17_+_36334147 0.01 ENSRNOT00000050261
E2F transcription factor 3
chr4_+_161685258 0.01 ENSRNOT00000008012
ENSRNOT00000008003
forkhead box M1
chr7_-_15364203 0.01 ENSRNOT00000036473
similar to KIAA1111-like protein
chr3_-_37445907 0.01 ENSRNOT00000006172
RNA binding motif protein 43
chr8_-_40122450 0.01 ENSRNOT00000039729
transforming growth factor beta regulator 1
chr9_-_82514399 0.01 ENSRNOT00000026799
aspartyl aminopeptidase
chr12_-_47482961 0.01 ENSRNOT00000001600
2'-5' oligoadenylate synthetase-like 2
chr1_-_266333105 0.01 ENSRNOT00000027093
ADP ribosylation factor like GTPase 3
chr1_+_13261876 0.00 ENSRNOT00000090703
RALBP1 associated Eps domain containing 1
chr7_-_24885775 0.00 ENSRNOT00000010024
t-complex 11 like 2
chr15_+_3996328 0.00 ENSRNOT00000088252
N-deacetylase and N-sulfotransferase 2
chr2_-_57196568 0.00 ENSRNOT00000060146
WD repeat domain 70
chr2_-_30633857 0.00 ENSRNOT00000085488
MARVEL domain containing 2
chr5_-_62153762 0.00 ENSRNOT00000066001
ENSRNOT00000086962
tripartite motif-containing 14
chrX_+_85338928 0.00 ENSRNOT00000074811
ENSRNOT00000006907
dachshund family transcription factor 2
chr12_-_9998779 0.00 ENSRNOT00000001265
ribosomal protein L21
chr15_+_3996048 0.00 ENSRNOT00000078653
N-deacetylase and N-sulfotransferase 2
chr17_-_69827112 0.00 ENSRNOT00000023835
aldo-keto reductase family 1, member C14
chr10_-_89454681 0.00 ENSRNOT00000028109
BRCA1, DNA repair associated
chr5_-_153924896 0.00 ENSRNOT00000065247
grainyhead-like transcription factor 3
chr1_-_79930263 0.00 ENSRNOT00000019219
forkhead box A3
chr20_+_25990304 0.00 ENSRNOT00000033980
leucine rich repeat transmembrane neuronal 3
chr10_+_76343847 0.00 ENSRNOT00000055674
tripartite motif-containing 25
chr13_+_82438697 0.00 ENSRNOT00000003759
selectin P
chr18_-_53181503 0.00 ENSRNOT00000066548
fibrillin 2
chr6_+_135866739 0.00 ENSRNOT00000013460
exocyst complex component 3-like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
0.0 0.2 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) advanced glycation end-product receptor activity(GO:0050785)
0.0 0.0 GO:0002134 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events