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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Klf15

Z-value: 0.84

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Transcription factors associated with Klf15

Gene Symbol Gene ID Gene Info
Klf15
ENSRNOG00000017808 Kruppel-like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf15rn6_v1_chr4_+_122365093_1223650930.069.3e-01Click!

Activity profile of Klf15 motif

Sorted Z-values of Klf15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_226435979 0.67 ENSRNOT00000048704
ENSRNOT00000036232
ENSRNOT00000035576
ENSRNOT00000036180
ENSRNOT00000036168
ENSRNOT00000047964
ENSRNOT00000036283
ENSRNOT00000007429
Syt7
synaptotagmin 7
chr10_-_85517683 0.48 ENSRNOT00000016070
Srcin1
SRC kinase signaling inhibitor 1
chr12_-_16002788 0.45 ENSRNOT00000090318
Amz1
archaelysin family metallopeptidase 1
chr20_-_5064469 0.37 ENSRNOT00000001120
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr7_+_130474279 0.35 ENSRNOT00000092388
Shank3
SH3 and multiple ankyrin repeat domains 3
chr3_+_41019898 0.32 ENSRNOT00000007335
Kcnj3
potassium voltage-gated channel subfamily J member 3
chr5_-_172623899 0.28 ENSRNOT00000080591
Ski
SKI proto-oncogene
chr15_+_34520142 0.28 ENSRNOT00000074659
Nynrin
NYN domain and retroviral integrase containing
chr12_-_36398206 0.27 ENSRNOT00000090944
ENSRNOT00000058492
Tmem132b
transmembrane protein 132B
chr18_-_86878142 0.26 ENSRNOT00000058139
Dok6
docking protein 6
chr15_+_120372 0.23 ENSRNOT00000007828
Dlg5
discs large MAGUK scaffold protein 5
chr3_-_7422738 0.23 ENSRNOT00000088339
Gtf3c4
general transcription factor IIIC subunit 4
chr19_-_41798383 0.22 ENSRNOT00000021744
Phlpp2
PH domain and leucine rich repeat protein phosphatase 2
chr3_-_1924827 0.22 ENSRNOT00000006162
Cacna1b
calcium voltage-gated channel subunit alpha1 B
chrX_+_71155601 0.22 ENSRNOT00000076453
ENSRNOT00000048521
Foxo4
forkhead box O4
chr3_+_58632476 0.21 ENSRNOT00000010630
Rapgef4
Rap guanine nucleotide exchange factor 4
chr3_-_164095878 0.21 ENSRNOT00000079414
B4galt5
beta-1,4-galactosyltransferase 5
chrX_-_22440187 0.21 ENSRNOT00000090731
Gpr173

chr20_+_4363508 0.19 ENSRNOT00000077205
Ager
advanced glycosylation end product-specific receptor
chr4_-_115157263 0.19 ENSRNOT00000015296
Tet3
tet methylcytosine dioxygenase 3
chr5_+_43603043 0.18 ENSRNOT00000009899
Epha7
Eph receptor A7
chr7_+_130474508 0.18 ENSRNOT00000085191
Shank3
SH3 and multiple ankyrin repeat domains 3
chr16_+_20740826 0.18 ENSRNOT00000038057
Crtc1
CREB regulated transcription coactivator 1
chr20_+_5646097 0.17 ENSRNOT00000090925
Itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr5_-_147412705 0.17 ENSRNOT00000010688
RGD1561149
similar to mKIAA1522 protein
chr7_-_139318455 0.17 ENSRNOT00000092029
Hdac7
histone deacetylase 7
chr5_+_139783951 0.17 ENSRNOT00000081333
Rims3
regulating synaptic membrane exocytosis 3
chr10_+_66690133 0.16 ENSRNOT00000046262
Nf1
neurofibromin 1
chr10_+_59360765 0.16 ENSRNOT00000036278
Zzef1
zinc finger ZZ-type and EF-hand domain containing 1
chr2_+_230901126 0.16 ENSRNOT00000016026
ENSRNOT00000015564
ENSRNOT00000068198
Camk2d
calcium/calmodulin-dependent protein kinase II delta
chr5_-_138545404 0.16 ENSRNOT00000011586
Rimkla
ribosomal modification protein rimK-like family member A
chr5_-_100647727 0.16 ENSRNOT00000067435
Nfib
nuclear factor I/B
chr5_+_74649765 0.15 ENSRNOT00000075952
Palm2
paralemmin 2
chr13_-_52256196 0.15 ENSRNOT00000011105
Ipo9
importin 9
chr7_-_143863186 0.15 ENSRNOT00000017096
Rarg
retinoic acid receptor, gamma
chr4_+_133286114 0.15 ENSRNOT00000084158
Ppp4r2
protein phosphatase 4, regulatory subunit 2
chrX_+_70596901 0.15 ENSRNOT00000088114
Dlg3
discs large MAGUK scaffold protein 3
chr1_+_80000165 0.15 ENSRNOT00000084912
Six5
SIX homeobox 5
chr7_+_97559841 0.15 ENSRNOT00000007326
Zhx2
zinc fingers and homeoboxes 2
chr2_+_198823366 0.14 ENSRNOT00000083769
ENSRNOT00000028814
Pias3
protein inhibitor of activated STAT, 3
chr13_+_34365147 0.14 ENSRNOT00000093066
Clasp1
cytoplasmic linker associated protein 1
chr14_+_83510278 0.14 ENSRNOT00000081161
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr1_-_164590562 0.13 ENSRNOT00000024157
Tpbgl
trophoblast glycoprotein-like
chr16_+_60925093 0.13 ENSRNOT00000015813
Tnks
tankyrase
chr11_-_38457373 0.13 ENSRNOT00000041177
Zfp295
zinc finger protein 295
chr19_+_25181564 0.13 ENSRNOT00000008104
Rfx1
regulatory factor X1
chr11_-_83926524 0.12 ENSRNOT00000041777
ENSRNOT00000040029
Eif4g1
eukaryotic translation initiation factor 4 gamma, 1
chr3_-_80003032 0.12 ENSRNOT00000017360
Madd
MAP-kinase activating death domain
chr3_-_57119001 0.12 ENSRNOT00000083171
Tlk1
tousled-like kinase 1
chr9_+_88357556 0.11 ENSRNOT00000020669
Col4a3
collagen type IV alpha 3 chain
chr9_-_16979044 0.11 ENSRNOT00000073191
ENSRNOT00000025335
Zfp318
zinc finger protein 318
chr8_+_79159370 0.11 ENSRNOT00000086841
Rfx7
regulatory factor X, 7
chr14_+_60857989 0.11 ENSRNOT00000034411
Ccdc149
coiled-coil domain containing 149
chr11_+_24263281 0.10 ENSRNOT00000086946
Gabpa
GA binding protein transcription factor, alpha subunit
chr5_+_63056089 0.10 ENSRNOT00000081090
Tgfbr1
transforming growth factor, beta receptor 1
chr14_-_82287706 0.10 ENSRNOT00000080695
Fgfr3
fibroblast growth factor receptor 3
chr20_+_4363152 0.10 ENSRNOT00000000508
ENSRNOT00000084841
ENSRNOT00000072848
ENSRNOT00000077561
Ager
advanced glycosylation end product-specific receptor
chr6_-_50943488 0.10 ENSRNOT00000068419
Dus4l
dihydrouridine synthase 4-like
chr7_+_122818975 0.10 ENSRNOT00000000206
Ep300
E1A binding protein p300
chr6_-_111329882 0.09 ENSRNOT00000074480
Ism2
isthmin 2
chr8_+_117737387 0.09 ENSRNOT00000090164
ENSRNOT00000091573
Pfkfb4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr7_+_123381077 0.09 ENSRNOT00000082603
ENSRNOT00000056041
Srebf2
sterol regulatory element binding transcription factor 2
chr10_+_90550147 0.09 ENSRNOT00000032944
Fzd2
frizzled class receptor 2
chr8_+_56179637 0.08 ENSRNOT00000035989
Arhgap20
Rho GTPase activating protein 20
chr1_+_78735678 0.08 ENSRNOT00000089715
Strn4
striatin 4
chr17_-_85141210 0.08 ENSRNOT00000000162
Dnajc1
DnaJ heat shock protein family (Hsp40) member C1
chr17_-_10640548 0.08 ENSRNOT00000064274
Simc1
SUMO-interacting motifs containing 1
chr7_-_90318221 0.08 ENSRNOT00000050774
Trps1
transcriptional repressor GATA binding 1
chr1_-_219532609 0.08 ENSRNOT00000025641
Ankrd13d
ankyrin repeat domain 13D
chr8_-_55408464 0.08 ENSRNOT00000066893
Sik2
salt-inducible kinase 2
chr7_-_77162148 0.07 ENSRNOT00000008350
Klf10
Kruppel-like factor 10
chr1_-_57327379 0.07 ENSRNOT00000080429
Dll1
delta like canonical Notch ligand 1
chr8_+_117780891 0.07 ENSRNOT00000077236
Shisa5
shisa family member 5
chr15_+_34493138 0.07 ENSRNOT00000089584
ENSRNOT00000027789
Nfatc4
nuclear factor of activated T-cells 4
chr8_-_116965396 0.07 ENSRNOT00000042528
Bsn
bassoon (presynaptic cytomatrix protein)
chr8_-_64268555 0.07 ENSRNOT00000013581
ENSRNOT00000084758
Arih1
ariadne RBR E3 ubiquitin protein ligase 1
chr3_-_91839009 0.07 ENSRNOT00000083703
Ldlrad3
low density lipoprotein receptor class A domain containing 3
chr7_-_70969905 0.06 ENSRNOT00000057745
Nab2
Ngfi-A binding protein 2
chr14_-_84106997 0.06 ENSRNOT00000065501
Osbp2
oxysterol binding protein 2
chr3_+_7422820 0.06 ENSRNOT00000064323
Ddx31
DEAD-box helicase 31
chr10_-_82197848 0.06 ENSRNOT00000081307
Cacna1g
calcium voltage-gated channel subunit alpha1 G
chr10_-_64862268 0.06 ENSRNOT00000056234
Phf12
PHD finger protein 12
chr18_-_47513030 0.06 ENSRNOT00000083881
ENSRNOT00000074226
Lox
lysyl oxidase
chr4_-_66002444 0.06 ENSRNOT00000018645
Zc3hav1l
zinc finger CCCH-type containing, antiviral 1 like
chr10_+_59585072 0.06 ENSRNOT00000025009
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1
chr19_+_38039564 0.06 ENSRNOT00000087491
Nfatc3
nuclear factor of activated T-cells 3
chr4_+_153217782 0.06 ENSRNOT00000015499
Cecr2
CECR2, histone acetyl-lysine reader
chr13_-_74077783 0.06 ENSRNOT00000005677
Soat1
sterol O-acyltransferase 1
chr13_+_89524329 0.06 ENSRNOT00000004279
Mpz
myelin protein zero
chr1_+_199225100 0.05 ENSRNOT00000088606
Setd1a
SET domain containing 1A
chr6_+_28235695 0.05 ENSRNOT00000047210
Dnmt3a
DNA methyltransferase 3 alpha
chr5_-_100647298 0.05 ENSRNOT00000067538
ENSRNOT00000013092
Nfib
nuclear factor I/B
chr17_-_80320681 0.05 ENSRNOT00000023637
C1ql3
complement C1q like 3
chr2_+_207108552 0.05 ENSRNOT00000027234
Slc16a1
solute carrier family 16 member 1
chr8_+_117068582 0.05 ENSRNOT00000073559
Amt
aminomethyltransferase
chr2_+_189615948 0.04 ENSRNOT00000092144
Crtc2
CREB regulated transcription coactivator 2
chr12_-_22417980 0.04 ENSRNOT00000072208
Ephb4
EPH receptor B4
chr1_+_282265370 0.04 ENSRNOT00000015687
Grk5
G protein-coupled receptor kinase 5
chr5_-_82168347 0.04 ENSRNOT00000084959
ENSRNOT00000084147
Astn2
astrotactin 2
chr1_+_78800754 0.04 ENSRNOT00000084601
Dact3
dishevelled-binding antagonist of beta-catenin 3
chr6_-_115352681 0.04 ENSRNOT00000005873
Gtf2a1
general transcription factor 2A subunit 1
chr6_-_46631983 0.04 ENSRNOT00000045963
Sox11
SRY box 11
chr2_-_29121104 0.04 ENSRNOT00000020543
Tnpo1
transportin 1
chr6_+_33786197 0.03 ENSRNOT00000082598
Pum2
pumilio RNA-binding family member 2
chr10_-_108691367 0.03 ENSRNOT00000005067
Nptx1
neuronal pentraxin 1
chr9_+_93326283 0.03 ENSRNOT00000024578
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr4_-_83137527 0.03 ENSRNOT00000039580
Jazf1
JAZF zinc finger 1
chr1_+_23977688 0.03 ENSRNOT00000014805
Tbpl1
TATA-box binding protein like 1
chr8_+_117737117 0.03 ENSRNOT00000028039
Pfkfb4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr10_-_88667345 0.03 ENSRNOT00000025518
Kcnh4
potassium voltage-gated channel subfamily H member 4
chr11_-_61499557 0.03 ENSRNOT00000046208
Usf3
upstream transcription factor family member 3
chr5_-_169167831 0.03 ENSRNOT00000012407
Phf13
PHD finger protein 13
chr4_-_152380023 0.03 ENSRNOT00000012397
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr1_+_174702373 0.02 ENSRNOT00000013733
Zfp143
zinc finger protein 143
chrX_-_123254557 0.02 ENSRNOT00000039809
Akap17b
A kinase (PRKA) anchor protein 17B
chr16_-_6404578 0.02 ENSRNOT00000051371
Cacna1d
calcium voltage-gated channel subunit alpha1 D
chr20_-_32052855 0.02 ENSRNOT00000074989
LOC100364027
hexokinase 1-like
chr8_+_97277456 0.02 ENSRNOT00000082757
Rasgrf1
RAS protein-specific guanine nucleotide-releasing factor 1
chr19_+_38039729 0.02 ENSRNOT00000089783
Nfatc3
nuclear factor of activated T-cells 3
chr2_+_62150493 0.02 ENSRNOT00000080241
Zfr
zinc finger RNA binding protein
chr8_+_130581062 0.02 ENSRNOT00000014323
Fam198a
family with sequence similarity 198, member A
chr1_-_199395363 0.02 ENSRNOT00000090368
ENSRNOT00000026587
Prss36
protease, serine, 36
chr1_+_101610773 0.02 ENSRNOT00000032535
Rasip1
Ras interacting protein 1
chr10_-_59360661 0.02 ENSRNOT00000036942
Cyb5d2
cytochrome b5 domain containing 2
chr7_-_143966863 0.02 ENSRNOT00000018828
Sp7
Sp7 transcription factor
chr17_-_9519595 0.02 ENSRNOT00000029885
Ddx46
DEAD-box helicase 46
chr10_-_85124644 0.02 ENSRNOT00000012376
Kpnb1
karyopherin subunit beta 1
chrX_-_118615798 0.01 ENSRNOT00000045463
Lrch2
leucine rich repeats and calponin homology domain containing 2
chr5_+_166533181 0.01 ENSRNOT00000045063
Clstn1
calsyntenin 1
chr8_+_45797315 0.01 ENSRNOT00000059997
AABR07070046.1

chr4_-_152380184 0.01 ENSRNOT00000091473
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr1_+_221099998 0.01 ENSRNOT00000028262
Ltbp3
latent transforming growth factor beta binding protein 3
chrX_+_112769645 0.01 ENSRNOT00000064478
Col4a5
collagen type IV alpha 5 chain
chr18_-_325374 0.01 ENSRNOT00000078032
ENSRNOT00000003638
Mtmr1
myotubularin related protein 1
chr4_+_133285552 0.01 ENSRNOT00000029115
Ppp4r2
protein phosphatase 4, regulatory subunit 2
chrX_+_27015884 0.01 ENSRNOT00000065814
Msl3
male-specific lethal 3 homolog (Drosophila)
chr6_-_111295917 0.01 ENSRNOT00000073428
ENSRNOT00000079373
Vipas39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr1_+_140762758 0.01 ENSRNOT00000047848
Acan
aggrecan
chr18_+_28781349 0.01 ENSRNOT00000026112
Psd2
pleckstrin and Sec7 domain containing 2
chr1_-_220786615 0.00 ENSRNOT00000038198
Tsga10ip
testis specific 10 interacting protein
chr1_+_226091774 0.00 ENSRNOT00000027693
Fads3
fatty acid desaturase 3
chr9_-_92435363 0.00 ENSRNOT00000093735
ENSRNOT00000022822
ENSRNOT00000093245
Trip12
thyroid hormone receptor interactor 12
chr4_-_71713063 0.00 ENSRNOT00000059447
Fam131b
family with sequence similarity 131, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.5 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.1 0.3 GO:1905204 response to selenite ion(GO:0072714) negative regulation of connective tissue replacement(GO:1905204)
0.1 0.2 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.1 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.0 0.1 GO:0036395 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:1905075 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.3 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0018076 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.2 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0045608 inhibition of neuroepithelial cell differentiation(GO:0002085) cerebellar cortex structural organization(GO:0021698) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.0 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0060170 ciliary membrane(GO:0060170)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.1 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.2 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription