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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Mnt

Z-value: 0.76

Motif logo

Transcription factors associated with Mnt

Gene Symbol Gene ID Gene Info
ENSRNOG00000002894 MAX network transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mntrn6_v1_chr10_+_61685241_61685241-0.434.8e-01Click!

Activity profile of Mnt motif

Sorted Z-values of Mnt motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_123119460 1.05 ENSRNOT00000028833
arginine vasopressin
chr2_-_197991198 0.73 ENSRNOT00000056322
circadian associated repressor of transcription
chr2_-_197991574 0.70 ENSRNOT00000085632
circadian associated repressor of transcription
chr17_-_9695292 0.63 ENSRNOT00000036162
proline rich 7 (synaptic)
chr2_-_187160373 0.53 ENSRNOT00000018961
neurotrophic receptor tyrosine kinase 1
chr7_-_13751271 0.45 ENSRNOT00000009931
solute carrier family 1 member 6
chr14_+_4362717 0.44 ENSRNOT00000002887
BarH-like homeobox 2
chr1_+_33910912 0.35 ENSRNOT00000044690
iroquois homeobox 1
chr11_-_36479868 0.35 ENSRNOT00000075762
non-histone chromosomal protein HMG-14-like
chr16_+_49462889 0.32 ENSRNOT00000039909
ankyrin repeat domain 37
chr3_-_66417741 0.31 ENSRNOT00000007662
neuronal differentiation 1
chr10_-_44746549 0.30 ENSRNOT00000003841
family with sequence similarity 183, member B
chr1_+_163445527 0.28 ENSRNOT00000020520
leucine rich repeat containing 32
chr13_-_90814119 0.28 ENSRNOT00000011208
transgelin 2
chr15_+_37790141 0.26 ENSRNOT00000076392
ENSRNOT00000091953
interleukin 17D
chr3_-_8852192 0.25 ENSRNOT00000022786
dolichol kinase
chr12_-_16934706 0.25 ENSRNOT00000001720
MAF bZIP transcription factor K
chr2_+_127538659 0.25 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr19_+_14508616 0.24 ENSRNOT00000019192
heme oxygenase 1
chr4_-_123118186 0.24 ENSRNOT00000038096
coiled-coil-helix-coiled-coil-helix domain containing 4
chr9_-_16848503 0.24 ENSRNOT00000024815
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr5_-_147953093 0.24 ENSRNOT00000075270
KH RNA binding domain containing, signal transduction associated 1
chr20_-_5533448 0.23 ENSRNOT00000000568
cutA divalent cation tolerance homolog
chr1_+_73719005 0.23 ENSRNOT00000025110
CDC42 effector protein 5
chr3_+_113415774 0.23 ENSRNOT00000056151
small EDRK-rich factor 2
chr4_+_33638709 0.22 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr20_-_5533600 0.22 ENSRNOT00000072319
cutA divalent cation tolerance homolog
chr20_+_13732198 0.22 ENSRNOT00000008608
macrophage migration inhibitory factor
chr6_+_33885495 0.21 ENSRNOT00000086633
syndecan 1
chr17_+_16333415 0.21 ENSRNOT00000060550
protein tyrosine phosphatase domain containing 1
chr4_-_82173207 0.21 ENSRNOT00000074167
homeo box A5
chr9_-_97065817 0.20 ENSRNOT00000026419
gastrulation brain homeobox 2
chr3_-_120306551 0.20 ENSRNOT00000021082
mal, T-cell differentiation protein-like
chr19_+_55669626 0.20 ENSRNOT00000033352
cadherin 15
chr8_-_66863476 0.20 ENSRNOT00000018820
ribosomal protein lateral stalk subunit P1
chr5_+_150725654 0.20 ENSRNOT00000089852
ENSRNOT00000017740
DnaJ heat shock protein family (Hsp40) member C8
chr2_+_189400696 0.20 ENSRNOT00000046919
ENSRNOT00000089801
similar to NICE-3
chr20_-_13706205 0.19 ENSRNOT00000038623
derlin 3
chr3_+_147643250 0.19 ENSRNOT00000000013
transcription factor 15
chr10_+_84152152 0.19 ENSRNOT00000010724
homeo box B5
chr1_+_261229347 0.19 ENSRNOT00000018485
ubiquitin domain containing 1
chr1_-_91042230 0.19 ENSRNOT00000073107
DNA-directed RNA polymerase II subunit RPB9
chr8_+_117117430 0.19 ENSRNOT00000073247
glutathione peroxidase 1
chr10_+_91710495 0.18 ENSRNOT00000033276
reprimo-like
chr6_+_42852683 0.18 ENSRNOT00000079185
ornithine decarboxylase 1
chr1_-_24191908 0.18 ENSRNOT00000061157
serum/glucocorticoid regulated kinase 1
chr7_-_18683440 0.18 ENSRNOT00000068323
ribosomal protein S28
chr1_-_255376833 0.18 ENSRNOT00000024941
protein phosphatase 1, regulatory subunit 3C
chr10_-_13536899 0.18 ENSRNOT00000008537
amidohydrolase domain containing 2
chrX_-_32355296 0.17 ENSRNOT00000081652
ENSRNOT00000065075
adaptor-related protein complex 1, sigma 2 subunit
chr8_-_104221342 0.17 ENSRNOT00000015476
ATPase Na+/K+ transporting subunit beta 3
chr9_+_98490608 0.17 ENSRNOT00000027232
kelch-like family member 30
chr4_-_165629996 0.17 ENSRNOT00000068185
ENSRNOT00000007427
Y box binding protein 3
chr5_+_150080072 0.16 ENSRNOT00000047917
transmembrane protein 200B
chr5_-_152464850 0.16 ENSRNOT00000021937
zinc finger protein 593
chr1_+_88686731 0.16 ENSRNOT00000028222
RNA polymerase II subunit I
chr10_+_55940533 0.15 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr16_+_80826681 0.15 ENSRNOT00000000123
coordinator of PRMT5 and differentiation stimulator
chr10_+_16542882 0.15 ENSRNOT00000028146
stanniocalcin 2
chr10_+_84135116 0.15 ENSRNOT00000031035
homeo box B7
chr7_+_3332788 0.15 ENSRNOT00000010180
Cd63 molecule
chr9_+_10446699 0.15 ENSRNOT00000075344
hypothetical LOC301124
chr3_+_61685619 0.14 ENSRNOT00000002140
homeo box D1
chr3_-_81282157 0.14 ENSRNOT00000051258
LARGE xylosyl- and glucuronyltransferase 2
chr11_-_60613718 0.14 ENSRNOT00000002906
autophagy related 3
chr2_+_189106039 0.14 ENSRNOT00000028210
ubiquitin conjugating enzyme E2 Q1
chr8_-_61917125 0.14 ENSRNOT00000085049
similar to human chromosome 15 open reading frame 39
chr7_-_140770647 0.14 ENSRNOT00000081784
complement C1q like 4
chr10_-_81587858 0.14 ENSRNOT00000003582
UTP18 small subunit processome component
chr1_-_78333321 0.14 ENSRNOT00000020402
SUMO1 activating enzyme subunit 1
chr16_-_81706664 0.14 ENSRNOT00000026580
lysosomal-associated membrane protein 1
chr7_+_18683553 0.14 ENSRNOT00000009425
NADH:ubiquinone oxidoreductase subunit A7
chr19_+_52225582 0.13 ENSRNOT00000020917
dynein, axonemal, assembly factor 1
chr10_+_16970626 0.13 ENSRNOT00000005383
dual specificity phosphatase 1
chr5_-_136721379 0.13 ENSRNOT00000026704
ATPase H+ transporting V0 subunit B
chr1_-_226255886 0.13 ENSRNOT00000027842
flap structure-specific endonuclease 1
chr7_+_128500011 0.13 ENSRNOT00000074625
family with sequence similarity 19 member A5, C-C motif chemokine like
chr1_+_240776969 0.13 ENSRNOT00000049732
similar to ribosomal protein S12
chr11_+_39482408 0.13 ENSRNOT00000075126
high mobility group nucleosome binding domain 1
chr10_-_57618527 0.13 ENSRNOT00000037517
complement C1q binding protein
chr1_+_12823363 0.13 ENSRNOT00000086790
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr11_+_47090245 0.13 ENSRNOT00000060645

chr17_+_54280851 0.13 ENSRNOT00000024022
Rho GTPase activating protein 12
chr1_-_214455039 0.13 ENSRNOT00000071028
RNA polymerase II subunit L
chr1_-_88686615 0.12 ENSRNOT00000070921
tubulin folding cofactor B
chr3_+_147358858 0.12 ENSRNOT00000012951
R-spondin 4
chr5_-_166726794 0.12 ENSRNOT00000022799
solute carrier family 25 member 33
chr10_+_83476107 0.12 ENSRNOT00000075733
prohibitin
chr9_-_113331319 0.12 ENSRNOT00000020681
VAMP associated protein A
chr1_+_40816107 0.11 ENSRNOT00000060767
A-kinase anchoring protein 12
chr1_-_101457126 0.11 ENSRNOT00000087061
ENSRNOT00000028328
BCL2 associated X, apoptosis regulator
chr1_-_101123402 0.11 ENSRNOT00000027976

chr16_+_69048730 0.11 ENSRNOT00000086082
ENSRNOT00000078128
RAB11 family interacting protein 1
chr8_+_39305128 0.11 ENSRNOT00000008285
fasciculation and elongation protein zeta 1
chr11_-_34598102 0.11 ENSRNOT00000068743
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_+_58565576 0.11 ENSRNOT00000026965
nucleoside-triphosphatase, cancer-related
chr1_+_82452469 0.11 ENSRNOT00000028026
exosome component 5
chr14_-_11198194 0.11 ENSRNOT00000003083
enolase-phosphatase 1
chr17_+_9837402 0.11 ENSRNOT00000076436
RAB24, member RAS oncogene family
chr1_-_84008293 0.11 ENSRNOT00000002053
small nuclear ribonucleoprotein polypeptide A
chr12_+_19573909 0.11 ENSRNOT00000029279
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr7_+_121480723 0.11 ENSRNOT00000065304
activating transcription factor 4
chr9_+_82345719 0.11 ENSRNOT00000057330
ENSRNOT00000078260
family with sequence similarity 134, member A
chr3_-_173953684 0.11 ENSRNOT00000090468
protein phosphatase 1, regulatory subunit 3D
chr1_-_64021321 0.10 ENSRNOT00000090819
ribosomal protein S9
chr16_-_75855745 0.10 ENSRNOT00000031291
1-acylglycerol-3-phosphate O-acyltransferase 5
chr10_-_13187461 0.10 ENSRNOT00000007039
protease, serine, 41
chr11_-_83985385 0.10 ENSRNOT00000002334
endothelin-converting enzyme 2-like
chr7_+_143882000 0.10 ENSRNOT00000017110
ENSRNOT00000091053
major facilitator superfamily domain containing 5
chr5_+_171242897 0.10 ENSRNOT00000032859
similar to RIKEN cDNA A430005L14
chr6_+_136150785 0.10 ENSRNOT00000078211
ENSRNOT00000015308
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
chr7_+_11521998 0.10 ENSRNOT00000026960
small glutamine rich tetratricopeptide repeat containing alpha
chr5_-_157820889 0.10 ENSRNOT00000024326
MRT4 homolog, ribosome maturation factor
chr7_+_77966722 0.10 ENSRNOT00000006142
collagen triple helix repeat containing 1
chr2_+_188489362 0.10 ENSRNOT00000027815
CDC-like kinase 2
chr10_-_89959176 0.10 ENSRNOT00000028264
membrane palmitoylated protein 3
chr5_-_138470096 0.10 ENSRNOT00000011392
phosphopantothenoylcysteine synthetase
chr20_-_5723902 0.10 ENSRNOT00000036871
ubiquinol-cytochrome c reductase complex assembly factor 2
chr7_+_121889157 0.10 ENSRNOT00000024835
family with sequence similarity 83, member F
chr3_-_161812243 0.10 ENSRNOT00000025238
ENSRNOT00000087646
solute carrier family 35 member C2
chr1_-_224986291 0.10 ENSRNOT00000026284
TATA-box binding protein associated factor 6 like
chr1_-_198706852 0.09 ENSRNOT00000024074
dCTP pyrophosphatase 1
chr17_-_9837293 0.09 ENSRNOT00000091320
ENSRNOT00000022134
PRELI domain containing 1
chr14_-_84189266 0.09 ENSRNOT00000005934
transcobalamin 2
chr10_+_103438303 0.09 ENSRNOT00000085262
Cd300a molecule
chr10_-_86509454 0.09 ENSRNOT00000009454
IKAROS family zinc finger 3
chr5_-_14356692 0.09 ENSRNOT00000085654
ATPase H+ transporting V1 subunit H
chr7_-_117788550 0.09 ENSRNOT00000021775
similar to RIKEN cDNA C030006K11
chr7_-_3346238 0.09 ENSRNOT00000010380
biogenesis of lysosomal organelles complex-1, subunit 1
chr12_+_12738812 0.09 ENSRNOT00000092233
ENSRNOT00000001379
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr4_+_78981987 0.09 ENSRNOT00000012490
coiled-coil domain containing 126
chr4_-_157679962 0.09 ENSRNOT00000050443
glyceraldehyde-3-phosphate dehydrogenase
chr18_-_81539065 0.08 ENSRNOT00000021400
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr3_+_72226613 0.08 ENSRNOT00000010619
translocase of inner mitochondrial membrane 10
chr9_-_9702306 0.08 ENSRNOT00000082341
thyroid hormone receptor interactor 10
chrX_+_62363953 0.08 ENSRNOT00000083362
aristaless related homeobox
chr10_-_40375605 0.08 ENSRNOT00000014464
annexin A6
chr11_-_34598275 0.08 ENSRNOT00000077233
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_-_73216251 0.08 ENSRNOT00000057587
ribosomal protein L30-like
chr1_-_199159125 0.08 ENSRNOT00000025618
BCL tumor suppressor 7C
chr9_+_69953440 0.08 ENSRNOT00000034740
eukaryotic translation elongation factor 1 beta 2
chr1_+_100393303 0.08 ENSRNOT00000026251
synaptotagmin 3
chr5_-_168004724 0.08 ENSRNOT00000024711
Parkinsonism associated deglycase
chr10_-_81653717 0.08 ENSRNOT00000003611
NME/NM23 nucleoside diphosphate kinase 2
chr1_-_82452281 0.08 ENSRNOT00000027995
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr10_-_89958805 0.08 ENSRNOT00000084266
membrane palmitoylated protein 3
chr20_-_6961162 0.08 ENSRNOT00000000635
mitochondrial carrier 1
chr7_-_73270308 0.08 ENSRNOT00000007430
reactive intermediate imine deaminase A homolog
chrX_+_43497763 0.08 ENSRNOT00000005014
peroxiredoxin 4
chr4_+_6827429 0.08 ENSRNOT00000071737
Ras homolog enriched in brain
chr11_+_80255790 0.08 ENSRNOT00000002522
B-cell CLL/lymphoma 6
chr8_+_50559126 0.08 ENSRNOT00000024918
apolipoprotein A5
chr1_+_221773254 0.08 ENSRNOT00000028646
RAS guanyl releasing protein 2
chr9_-_16612136 0.08 ENSRNOT00000023495
male-enhanced antigen 1
chr7_-_18554227 0.08 ENSRNOT00000036172
ENSRNOT00000011047
heterogeneous nuclear ribonucleoprotein M
chr12_+_22229079 0.08 ENSRNOT00000001911
G protein subunit beta 2
chr10_-_83898527 0.08 ENSRNOT00000009815
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr4_-_100099517 0.08 ENSRNOT00000014277
atonal bHLH transcription factor 8
chr3_+_11424099 0.08 ENSRNOT00000019184
prostaglandin E synthase 2
chr5_+_169506138 0.08 ENSRNOT00000014904
ribosomal protein L22
chr4_-_82258765 0.08 ENSRNOT00000008523
homeo box A5
chr10_+_82375572 0.08 ENSRNOT00000004947
mitochondrial ribosomal protein L27
chr1_+_222229835 0.08 ENSRNOT00000051749
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_+_170578889 0.08 ENSRNOT00000025906
integrin-linked kinase
chr19_-_49532811 0.08 ENSRNOT00000015967
glycine cleavage system protein H
chr10_+_103266296 0.07 ENSRNOT00000038852
dynein, axonemal, intermediate chain 2
chr18_+_70996044 0.07 ENSRNOT00000024950
ENSRNOT00000066336
dymeclin
chrX_-_156399760 0.07 ENSRNOT00000086921
family with sequence similarity 50, member A
chr1_+_173532803 0.07 ENSRNOT00000021017
eukaryotic translation initiation factor 3, subunit F
chr17_+_85356042 0.07 ENSRNOT00000022201
COMM domain containing 3
chr14_-_33580566 0.07 ENSRNOT00000063942
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr13_+_90514336 0.07 ENSRNOT00000088996
ENSRNOT00000085377
peroxisomal biogenesis factor 19
chr5_-_171312026 0.07 ENSRNOT00000063779
small integral membrane protein 1
chr5_-_135628750 0.07 ENSRNOT00000079236

chr1_-_265899958 0.07 ENSRNOT00000026013
paired-like homeodomain 3
chr10_-_56531483 0.07 ENSRNOT00000022343
eukaryotic translation initiation factor 5A
chr2_+_190007216 0.07 ENSRNOT00000015612
S100 calcium binding protein A6
chr9_-_66877972 0.07 ENSRNOT00000023463
WD repeat domain 12
chr1_-_164143818 0.07 ENSRNOT00000022557
diacylglycerol O-acyltransferase 2
chr4_+_342302 0.07 ENSRNOT00000009233
insulin induced gene 1
chr1_-_93949187 0.07 ENSRNOT00000018956
zinc finger protein 536
chr1_+_216293087 0.07 ENSRNOT00000027875
ENSRNOT00000087153
potassium voltage-gated channel subfamily Q member 1
chr4_+_7257752 0.07 ENSRNOT00000088357
transmembrane and ubiquitin-like domain containing 1
chr16_-_60427474 0.07 ENSRNOT00000051720
protein phosphatase 1, regulatory subunit 3B
chr3_-_12944494 0.07 ENSRNOT00000023172
multivesicular body subunit 12B
chr1_-_100980340 0.07 ENSRNOT00000064272
protein arginine methyltransferase 1
chr15_-_45376476 0.07 ENSRNOT00000065838
deleted in lymphocytic leukemia, 7
chr12_-_9864791 0.07 ENSRNOT00000073026
general transcription factor III A
chr2_+_115337439 0.07 ENSRNOT00000015779
eukaryotic translation initiation factor 5A2
chr4_+_99937558 0.06 ENSRNOT00000050249
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_+_77994203 0.06 ENSRNOT00000002044
NSF attachment protein alpha
chr5_+_152681101 0.06 ENSRNOT00000076052
ENSRNOT00000022574
stathmin 1
chr2_+_243105674 0.06 ENSRNOT00000013919
H2A histone family, member Z
chr12_+_22451596 0.06 ENSRNOT00000072838
thyroid hormone receptor interactor 6
chr7_+_71294140 0.06 ENSRNOT00000087143
phosphatidylserine synthase 1
chr20_+_31265483 0.06 ENSRNOT00000079584
ENSRNOT00000000674
pyrophosphatase (inorganic) 1
chr9_+_17817721 0.06 ENSRNOT00000086986
ENSRNOT00000026920
heat shock protein 90 alpha family class B member 1
chr12_+_23544287 0.06 ENSRNOT00000001938
ORAI calcium release-activated calcium modulator 2
chr1_-_163328591 0.06 ENSRNOT00000034843
tsukushi, small leucine rich proteoglycan
chr4_-_82160240 0.06 ENSRNOT00000038775
ENSRNOT00000058985
homeo box A4

Network of associatons between targets according to the STRING database.

First level regulatory network of Mnt

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.3 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
0.1 0.3 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:0072268 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.1 0.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:0009609 response to symbiotic bacterium(GO:0009609)
0.1 1.4 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.2 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
0.0 0.1 GO:0019740 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:1990737 negative regulation of translational initiation in response to stress(GO:0032057) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0060101 negative regulation of phagocytosis, engulfment(GO:0060101) negative regulation of eosinophil migration(GO:2000417)
0.0 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:1903195 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) TRAIL receptor biosynthetic process(GO:0045557) regulation of TRAIL receptor biosynthetic process(GO:0045560) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.0 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0045901 regulation of translational termination(GO:0006449) positive regulation of translational elongation(GO:0045901)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0034475 U4 snRNA 3'-end processing(GO:0034475) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.0 GO:0080033 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:1904585 response to sodium phosphate(GO:1904383) response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:0018201 N-terminal protein amino acid methylation(GO:0006480) peptidyl-glycine modification(GO:0018201)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.0 GO:0051695 actin filament uncapping(GO:0051695) positive regulation of endocytic recycling(GO:2001137)
0.0 0.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.0 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:1904587 response to glycoprotein(GO:1904587)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.0 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.0 0.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.0 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0061474 phagolysosome membrane(GO:0061474)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0036398 TCR signalosome(GO:0036398) microspike(GO:0044393)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0002134 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.0 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)