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GSE49485: Hypoxia transcriptome sequencing of rat brain.

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Results for Nr1i3

Z-value: 0.58

Motif logo

Transcription factors associated with Nr1i3

Gene Symbol Gene ID Gene Info
ENSRNOG00000003260 nuclear receptor subfamily 1, group I, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1i3rn6_v1_chr13_+_89586283_895863360.227.2e-01Click!

Activity profile of Nr1i3 motif

Sorted Z-values of Nr1i3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_40227297 0.19 ENSRNOT00000030600
family with sequence similarity 109, member A
chr8_-_132345708 0.18 ENSRNOT00000006300
transmembrane protein 158
chr3_+_152571121 0.18 ENSRNOT00000087289
ENSRNOT00000080543
ENSRNOT00000083476
erythrocyte membrane protein band 4.1-like 1
chr17_-_61332391 0.18 ENSRNOT00000034599
SNRPN upstream reading frame protein-like
chr2_-_259150479 0.17 ENSRNOT00000085892

chr16_+_73755539 0.17 ENSRNOT00000088219
tissue-type plasminogen activator-like
chrX_-_106607352 0.17 ENSRNOT00000082858

chr7_+_121311024 0.16 ENSRNOT00000092260
ENSRNOT00000023066
ENSRNOT00000081377
synaptogyrin 1
chr13_-_70667658 0.16 ENSRNOT00000092521
laminin subunit gamma 1
chr6_-_135939534 0.15 ENSRNOT00000052237
DIRAS family GTPase 3
chr1_-_201906286 0.15 ENSRNOT00000064511
ENSRNOT00000036625
similar to RIKEN cDNA 1700063I17
chr2_-_198412350 0.14 ENSRNOT00000040210
histone H4-like
chr12_-_22245100 0.14 ENSRNOT00000001912
GRB10 interacting GYF protein 1
chr4_+_78263866 0.14 ENSRNOT00000033807
expressed sequence AI854703
chr3_+_147609095 0.14 ENSRNOT00000041456
sulfiredoxin 1
chr1_-_80744831 0.14 ENSRNOT00000025913
B-cell CLL/lymphoma 3
chr5_+_74874306 0.14 ENSRNOT00000076918
A-kinase anchoring protein 2
chr5_-_152473868 0.14 ENSRNOT00000022130
family with sequence similarity 110, member D
chr4_-_108717309 0.14 ENSRNOT00000085062

chr8_+_116776494 0.14 ENSRNOT00000050702
cadherin-related family member 4
chr20_+_6351458 0.13 ENSRNOT00000091731
cyclin-dependent kinase inhibitor 1A
chr10_-_85435016 0.13 ENSRNOT00000079921
RIKEN cDNA 4933428G20 gene
chr2_-_225107283 0.13 ENSRNOT00000055711
solute carrier family 44, member 3
chr8_+_118662335 0.13 ENSRNOT00000029755
neutrophilic granule protein
chr4_-_100783750 0.13 ENSRNOT00000078956
potassium channel modulatory factor 1
chrX_+_15113878 0.12 ENSRNOT00000007464
WD repeat domain 13
chr6_+_26390689 0.12 ENSRNOT00000079762
ENSRNOT00000091528
intraflagellar transport 172
chr1_+_78876205 0.12 ENSRNOT00000022610
paraneoplastic Ma antigen family-like 2
chr2_+_235596907 0.12 ENSRNOT00000071463
ENSRNOT00000075728
collagen type XXV alpha 1 chain
chr4_+_119815139 0.12 ENSRNOT00000083402
ENSRNOT00000016137
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
chr1_+_90948976 0.12 ENSRNOT00000056877
succinate dehydrogenase assembly factor 1, mitochondrial
chr14_-_114649173 0.12 ENSRNOT00000083528
spectrin, beta, non-erythrocytic 1
chr3_-_153876938 0.12 ENSRNOT00000087907
band 4.1-like protein 1-like
chr13_+_110920830 0.12 ENSRNOT00000077014
ENSRNOT00000076362
potassium voltage-gated channel subfamily H member 1
chr12_-_30304036 0.12 ENSRNOT00000001218
nuclear protein 2, transcriptional regulator
chr19_+_740028 0.12 ENSRNOT00000076604
dynein, cytoplasmic 1 light intermediate chain 2
chr4_+_100209951 0.12 ENSRNOT00000015807
hypothetical protein LOC691113
chr11_+_89008008 0.12 ENSRNOT00000074586
CCAAT/enhancer binding protein delta
chr12_+_37878653 0.11 ENSRNOT00000091084
phosphatidylinositol transfer protein, membrane-associated 2
chr13_-_88642011 0.11 ENSRNOT00000067037
hypothetical LOC100361087
chr1_-_215284548 0.11 ENSRNOT00000090375
cortactin
chr1_-_204275803 0.11 ENSRNOT00000066711
carbohydrate sulfotransferase 15
chr10_-_103848035 0.11 ENSRNOT00000029001
fatty acid desaturase 6
chr12_-_2610917 0.11 ENSRNOT00000034124
ecotropic viral integration site 5-like
chr7_+_127081978 0.11 ENSRNOT00000022945
TBC1 domain family, member 22a
chr6_-_41870046 0.11 ENSRNOT00000005863
lipin 1
chr3_-_13525983 0.11 ENSRNOT00000082036
PBX homeobox 3
chr7_-_44121130 0.11 ENSRNOT00000005706
neurotensin
chr12_-_2555164 0.11 ENSRNOT00000084460
ENSRNOT00000061821
mitogen activated protein kinase kinase 7
chr7_-_12275609 0.11 ENSRNOT00000086061
APC2, WNT signaling pathway regulator
chr1_+_213583606 0.11 ENSRNOT00000088899

chr4_+_64088900 0.11 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr11_+_61531416 0.11 ENSRNOT00000093263
ATPase H+ transporting V1 subunit A
chr6_+_132219088 0.11 ENSRNOT00000034883
HHIP-like 1
chr1_-_142724511 0.10 ENSRNOT00000014639
neuromedin B
chr6_-_104631355 0.10 ENSRNOT00000007825
solute carrier family 10 member 1
chr16_+_20578131 0.10 ENSRNOT00000026713
single stranded DNA binding protein 4
chr12_-_47987255 0.10 ENSRNOT00000074000
ubiquitin protein ligase E3B
chr20_+_3149114 0.10 ENSRNOT00000084770
RT1 class Ib, locus N2
chr1_+_199449973 0.10 ENSRNOT00000029994
tripartite motif containing 72
chr5_-_17061837 0.10 ENSRNOT00000011892
proenkephalin
chr4_+_199916 0.10 ENSRNOT00000009317
5-hydroxytryptamine receptor 5A
chr6_+_76677213 0.10 ENSRNOT00000076760
breast cancer metastasis-suppressor 1-like
chr3_-_120306551 0.10 ENSRNOT00000021082
mal, T-cell differentiation protein-like
chr17_-_14058642 0.10 ENSRNOT00000019489
nucleoredoxin-like 2
chr20_+_4993560 0.10 ENSRNOT00000081628
ENSRNOT00000087861
ENSRNOT00000001160
valyl-tRNA synthetase
chr12_-_35979193 0.10 ENSRNOT00000071104
transmembrane protein 132B
chr9_+_10471742 0.10 ENSRNOT00000072276
scaffold attachment factor B2
chr14_+_86652365 0.10 ENSRNOT00000077428
zinc finger, MIZ-type containing 2
chr17_+_76079720 0.10 ENSRNOT00000073933
proline and serine rich 2
chr1_+_80279706 0.10 ENSRNOT00000047105
protein phosphatase 1, regulatory subunit 13 like
chr7_+_20462081 0.10 ENSRNOT00000088383

chr18_-_56325095 0.10 ENSRNOT00000025209
solute carrier family 6 member 7
chr10_-_105368242 0.10 ENSRNOT00000075293
ENSRNOT00000072230
ring finger protein 157
chr12_+_32103198 0.09 ENSRNOT00000085464
transmembrane protein 132D
chr4_+_170149029 0.09 ENSRNOT00000073287
histone H2A.J
chr1_-_200548317 0.09 ENSRNOT00000088610

chr19_-_36239712 0.09 ENSRNOT00000071962

chr10_+_103737162 0.09 ENSRNOT00000055037
transmembrane protein 104
chr11_-_25350974 0.09 ENSRNOT00000002187
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_-_10659357 0.09 ENSRNOT00000091450
lysine demethylase 4B
chr8_-_71728654 0.09 ENSRNOT00000031207
ENSRNOT00000091751
sorting nexin 22
chr16_-_70705128 0.09 ENSRNOT00000071258
ring finger protein 170
chr17_+_76002275 0.09 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr8_+_49441106 0.09 ENSRNOT00000030152
sodium voltage-gated channel beta subunit 4
chr3_+_145764932 0.09 ENSRNOT00000075257

chr19_+_24800072 0.09 ENSRNOT00000005470
prostaglandin E receptor 1
chr6_+_10348308 0.09 ENSRNOT00000034991
endothelial PAS domain protein 1
chr3_+_103773459 0.09 ENSRNOT00000079727
solute carrier family 12, member 6
chr7_-_98735192 0.09 ENSRNOT00000051430

chr14_+_1355004 0.09 ENSRNOT00000043131

chr11_+_83855753 0.09 ENSRNOT00000030686
similar to 60S ribosomal protein L12
chr1_+_242572533 0.09 ENSRNOT00000035123
transmembrane protein 252
chr9_-_15628881 0.09 ENSRNOT00000077318
ENSRNOT00000020950
guanylate cyclase activator 1B
chr4_+_40161285 0.09 ENSRNOT00000050722
hypothetical protein LOC500035
chr10_+_47019326 0.09 ENSRNOT00000006984
Smith-Magenis syndrome chromosome region, candidate 8
chrX_+_111735820 0.09 ENSRNOT00000086948
FERM and PDZ domain containing 3
chr2_+_260997497 0.09 ENSRNOT00000012638
glutamate-rich 3
chr10_+_63829807 0.08 ENSRNOT00000006407
CRK proto-oncogene, adaptor protein
chr1_+_166125474 0.08 ENSRNOT00000091822
FCH and double SH3 domains 2
chr7_+_70283710 0.08 ENSRNOT00000075371
CTD small phosphatase 2
chr14_-_114583122 0.08 ENSRNOT00000084595
spectrin, beta, non-erythrocytic 1
chr1_+_214927172 0.08 ENSRNOT00000027134
BR serine/threonine kinase 2
chr15_-_70399924 0.08 ENSRNOT00000087940
diaphanous-related formin 3
chr8_+_49418965 0.08 ENSRNOT00000021819
sodium voltage-gated channel beta subunit 2
chr7_+_130474508 0.08 ENSRNOT00000085191
SH3 and multiple ankyrin repeat domains 3
chr10_+_57218087 0.08 ENSRNOT00000089853
misshapen-like kinase 1
chr9_-_28732919 0.08 ENSRNOT00000083915
regulating synaptic membrane exocytosis 1
chr12_+_25119355 0.08 ENSRNOT00000034629
linker for activation of T cells family, member 2
chr7_+_130498199 0.08 ENSRNOT00000092684
ENSRNOT00000092431
SH3 and multiple ankyrin repeat domains 3
chr10_-_90994437 0.08 ENSRNOT00000093167
glial fibrillary acidic protein
chr5_-_105579959 0.08 ENSRNOT00000010827
solute carrier family 24 member 2
chr1_+_203971152 0.08 ENSRNOT00000075540
G protein-coupled receptor 26
chr8_+_118378059 0.08 ENSRNOT00000043247

chr1_+_27924825 0.08 ENSRNOT00000087830

chr10_-_63952726 0.08 ENSRNOT00000090461
double C2 domain beta
chr5_+_16463597 0.08 ENSRNOT00000091550

chr14_+_79205466 0.08 ENSRNOT00000085534
TBC1 domain family, member 14
chr2_-_62634785 0.08 ENSRNOT00000017937
PDZ domain containing 2
chr19_+_755460 0.08 ENSRNOT00000076560
dynein, cytoplasmic 1 light intermediate chain 2
chr16_+_19051965 0.08 ENSRNOT00000016399
solute carrier family 35, member E1
chr20_-_14620019 0.08 ENSRNOT00000001779
G protein subunit alpha z
chr1_+_24900858 0.08 ENSRNOT00000075616
similar to spermatogenesis associated glutamate (E)-rich protein 4d
chr6_+_145770662 0.08 ENSRNOT00000088969
cell division cycle associated 7 like
chr9_-_10471009 0.07 ENSRNOT00000072868
scaffold attachment factor B
chr20_+_4824226 0.07 ENSRNOT00000001113
NFKB inhibitor like 1
chr16_+_70081035 0.07 ENSRNOT00000016098
ubiquitin carboxyl-terminal hydrolase 12-like
chr2_+_206064179 0.07 ENSRNOT00000025953
synaptotagmin 6
chr14_+_42015347 0.07 ENSRNOT00000044017
ATPase phospholipid transporting 8A1
chr8_+_116332796 0.07 ENSRNOT00000021408
hyaluronoglucosaminidase 1
chr2_-_200003443 0.07 ENSRNOT00000024900
ENSRNOT00000088041
phosphodiesterase 4D interacting protein
chr1_+_199495298 0.07 ENSRNOT00000086003
ENSRNOT00000026748
integrin subunit alpha D
chr17_-_43815183 0.07 ENSRNOT00000073188
histone cluster 1, H2ai-like1
chr4_-_155563249 0.07 ENSRNOT00000011298
solute carrier family 2 member 3
chr8_-_73122740 0.07 ENSRNOT00000012026
talin 2
chr12_-_30770791 0.07 ENSRNOT00000093734
splicing factor SWAP homolog
chr6_+_137164535 0.07 ENSRNOT00000018225
inverted formin, FH2 and WH2 domain containing
chr19_-_54648227 0.07 ENSRNOT00000025424
kelch domain containing 4
chr5_-_137372524 0.07 ENSRNOT00000009061
transmembrane protein 125
chr7_+_12471824 0.07 ENSRNOT00000068197
strawberry notch homolog 2
chrX_+_158351156 0.07 ENSRNOT00000080538
protein FAM122B-like
chr2_-_115891097 0.07 ENSRNOT00000013191
SKI-like proto-oncogene
chr4_+_117743710 0.07 ENSRNOT00000021491
adducin 2
chr4_-_179477070 0.07 ENSRNOT00000030680
cancer susceptibility candidate 1
chr11_+_32440237 0.07 ENSRNOT00000040844
potassium voltage-gated channel subfamily E regulatory subunit 2
chr1_+_84411726 0.07 ENSRNOT00000025303
AKT serine/threonine kinase 2
chr11_-_30051103 0.07 ENSRNOT00000046486
T-cell lymphoma invasion and metastasis 1
chr8_-_118378460 0.07 ENSRNOT00000047247
similar to ribosomal protein S23
chr10_+_56381813 0.07 ENSRNOT00000019687
zinc finger and BTB domain containing 4
chr10_-_5196892 0.07 ENSRNOT00000083982
C-type lectin domain family 16, member A
chr2_+_187990242 0.07 ENSRNOT00000092819
Rho/Rac guanine nucleotide exchange factor 2
chr8_+_22047697 0.07 ENSRNOT00000067741
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr2_+_45668969 0.07 ENSRNOT00000014761
ENSRNOT00000071353
ADP-ribosylation factor like GTPase 15
chr10_+_47018974 0.07 ENSRNOT00000079375
Smith-Magenis syndrome chromosome region, candidate 8
chr1_+_72882806 0.07 ENSRNOT00000024640
troponin I3, cardiac type
chr6_+_146784915 0.07 ENSRNOT00000008362
Sp8 transcription factor
chr13_+_51795867 0.07 ENSRNOT00000006747
ubiquitin-conjugating enzyme E2T
chr20_+_3823596 0.07 ENSRNOT00000087670
retinoid X receptor beta
chr3_+_162346490 0.07 ENSRNOT00000087530
EYA transcriptional coactivator and phosphatase 2
chrX_+_15114892 0.07 ENSRNOT00000078168
WD repeat domain 13
chr10_-_14299167 0.07 ENSRNOT00000042066
mitogen-activated protein kinase 8 interacting protein 3
chr2_-_77632628 0.07 ENSRNOT00000073915
brain abundant, membrane attached signal protein 1
chr3_+_71114100 0.07 ENSRNOT00000088549
ENSRNOT00000006961
integrin subunit alpha V
chr4_-_176679815 0.07 ENSRNOT00000090122
glycogen synthase 2
chr9_-_10462491 0.07 ENSRNOT00000081770
scaffold attachment factor B
chr3_+_151126591 0.06 ENSRNOT00000025859
myosin heavy chain 7B
chr4_+_145427367 0.06 ENSRNOT00000037788
interleukin 17 receptor C
chr14_-_5006594 0.06 ENSRNOT00000076571
zinc finger protein 326
chr9_+_98190829 0.06 ENSRNOT00000050191
LRR binding FLII interacting protein 1
chr2_-_257474733 0.06 ENSRNOT00000016967
ENSRNOT00000066780
nexilin (F actin binding protein)
chr7_-_26690323 0.06 ENSRNOT00000087536
carbohydrate sulfotransferase 11
chr10_+_46092754 0.06 ENSRNOT00000080666
myosin phosphatase Rho interacting protein
chr19_+_43882249 0.06 ENSRNOT00000025761
zinc finger protein 1
chr12_-_37910439 0.06 ENSRNOT00000001433
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr17_+_44758460 0.06 ENSRNOT00000089436
histone cluster 1, H2an
chr19_+_52664322 0.06 ENSRNOT00000082754
cysteine-rich secretory protein LCCL domain containing 2
chr1_-_72366455 0.06 ENSRNOT00000031786
zinc finger protein 865-like
chr11_+_69484293 0.06 ENSRNOT00000049292
kalirin, RhoGEF kinase
chr6_+_106039991 0.06 ENSRNOT00000088917
signal-induced proliferation-associated 1 like 1
chr14_+_83724933 0.06 ENSRNOT00000029848
phospholipase A2, group III
chr9_+_10773901 0.06 ENSRNOT00000070978
perilipin 3
chr7_-_125497691 0.06 ENSRNOT00000049445

chr10_+_40553180 0.06 ENSRNOT00000087763
solute carrier family 36 member 1
chr5_+_124476168 0.06 ENSRNOT00000077754
similar to novel protein
chr3_+_8701855 0.06 ENSRNOT00000021431
TBC1 domain family, member 13
chr11_+_64472072 0.06 ENSRNOT00000042756
similar to ribosomal protein L27
chr3_-_155192806 0.06 ENSRNOT00000051343
similar to 60S ribosomal protein L13
chr1_-_16203838 0.06 ENSRNOT00000018556
ENSRNOT00000078586
phosphodiesterase 7B
chr3_+_171832500 0.06 ENSRNOT00000007554
VAMP associated protein B and C
chr10_+_90731865 0.06 ENSRNOT00000064429
ADAM metallopeptidase domain 11
chr4_-_77706994 0.06 ENSRNOT00000038517
zinc finger protein 777
chr12_-_48857724 0.06 ENSRNOT00000080783
WSC domain containing 2
chr5_+_172273459 0.06 ENSRNOT00000017957
membrane metallo-endopeptidase-like 1
chr3_-_6626284 0.06 ENSRNOT00000012494
ficolin B
chr7_-_15073052 0.06 ENSRNOT00000037708
zinc finger protein 799
chr8_-_55276070 0.06 ENSRNOT00000041555
60S ribosomal protein L27a-like
chr10_+_109893700 0.06 ENSRNOT00000082551
leucine rich repeat containing 45
chr19_-_11302938 0.06 ENSRNOT00000038212

chr10_-_40375605 0.06 ENSRNOT00000014464
annexin A6
chr10_-_50402616 0.06 ENSRNOT00000004546
heparan sulfate-glucosamine 3-sulfotransferase 3B1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1i3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:1904054 regulation of cholangiocyte proliferation(GO:1904054) positive regulation of cholangiocyte proliferation(GO:1904056)
0.0 0.1 GO:0031439 positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
0.0 0.1 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644) retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:1990859 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:0097332 response to antipsychotic drug(GO:0097332)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0036146 cellular response to mycotoxin(GO:0036146)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
0.0 0.0 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.0 GO:1900095 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.0 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.0 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.0 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.0 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:1900451 positive regulation of glutamate receptor signaling pathway(GO:1900451)
0.0 0.0 GO:1901423 response to benzene(GO:1901423)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.0 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.0 GO:1904373 response to kainic acid(GO:1904373)
0.0 0.0 GO:1903373 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.0 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.0 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:2001137 actin filament uncapping(GO:0051695) positive regulation of endocytic recycling(GO:2001137)
0.0 0.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0036394 amylase secretion(GO:0036394)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0061525 hindgut development(GO:0061525)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.0 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.0 0.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.0 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0099571 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.1 GO:1990005 granular vesicle(GO:1990005)
0.0 0.1 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.0 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.0 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.0 GO:0031309 intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0031249 denatured protein binding(GO:0031249)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0033222 xylose binding(GO:0033222)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.1 GO:0001565 phorbol ester receptor activity(GO:0001565)
0.0 0.1 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0038132 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.0 0.0 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.0 GO:0000250 lanosterol synthase activity(GO:0000250) oxidosqualene cyclase activity(GO:0031559)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.0 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts