Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Arid5b

Z-value: 0.63

Motif logo

logo of

Transcription factors associated with Arid5b

Gene Symbol Gene ID Gene Info
Arid5b
ENSRNOG00000000635 Arid5b

Activity profile of Arid5b motif

Sorted Z-values of Arid5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_47721977 32.89 ENSRNOT00000080800
LOC100910792
amphiphysin-like
chr1_-_150395415 19.94 ENSRNOT00000018592
Folh1
folate hydrolase 1
chr6_-_88917070 17.45 ENSRNOT00000000767
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr4_-_11497531 15.70 ENSRNOT00000078799
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_30574627 14.22 ENSRNOT00000060484
Pcdhb19
protocadherin beta 19
chr3_+_117421604 13.54 ENSRNOT00000008860
ENSRNOT00000008857
Slc12a1
solute carrier family 12 member 1
chr10_-_59883839 13.39 ENSRNOT00000093579
Aspa
aspartoacylase
chr2_+_121165137 13.01 ENSRNOT00000016236
Sox2
SRY box 2
chr2_+_236625357 12.85 ENSRNOT00000081248
Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr7_-_12874215 12.09 ENSRNOT00000011837
Hcn2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr3_-_46726946 11.77 ENSRNOT00000011030
ENSRNOT00000086576
Itgb6
integrin subunit beta 6
chr6_-_43862131 11.70 ENSRNOT00000089859
Cys1
cystin 1
chr4_+_140377565 11.60 ENSRNOT00000082723
Itpr1
inositol 1,4,5-trisphosphate receptor, type 1
chr14_-_66978499 11.37 ENSRNOT00000081601
Slit2
slit guidance ligand 2
chr2_+_83393282 10.59 ENSRNOT00000044871
Ctnnd2
catenin delta 2
chr2_-_9023104 9.98 ENSRNOT00000039652
Adgrv1
adhesion G protein-coupled receptor V1
chr9_-_79898912 9.97 ENSRNOT00000022076
March4
membrane associated ring-CH-type finger 4
chr6_-_42630983 9.58 ENSRNOT00000071977
Atp6v1c2
ATPase H+ transporting V1 subunit C2
chr1_-_100969560 9.29 ENSRNOT00000035908
Cpt1c
carnitine palmitoyltransferase 1c
chr2_-_197991198 9.28 ENSRNOT00000056322
Ciart
circadian associated repressor of transcription
chr2_-_26699333 8.56 ENSRNOT00000024459
Sv2c
synaptic vesicle glycoprotein 2c
chr10_-_66848388 8.55 ENSRNOT00000018891
Omg
oligodendrocyte-myelin glycoprotein
chr18_-_58423196 8.51 ENSRNOT00000025556
Piezo2
piezo-type mechanosensitive ion channel component 2
chr20_+_3558827 8.26 ENSRNOT00000088130
Ddr1
discoidin domain receptor tyrosine kinase 1
chr4_+_61912210 8.18 ENSRNOT00000013569
Bpgm
bisphosphoglycerate mutase
chr1_+_153861948 8.10 ENSRNOT00000087067
Me3
malic enzyme 3
chr18_+_29352749 7.91 ENSRNOT00000025137
Slc4a9
solute carrier family 4 member 9
chr4_-_55398941 7.81 ENSRNOT00000075324
Grm8
glutamate metabotropic receptor 8
chr3_-_13525983 7.63 ENSRNOT00000082036
Pbx3
PBX homeobox 3
chr1_-_157461588 7.18 ENSRNOT00000068402
Ankrd42
ankyrin repeat domain 42
chr1_+_170205591 6.98 ENSRNOT00000071063
LOC686660
similar to olfactory receptor 692
chr5_-_16140896 6.86 ENSRNOT00000029503
Xkr4
XK related 4
chr5_-_173233188 6.52 ENSRNOT00000055343
Tmem88b
transmembrane protein 88B
chr1_-_43638161 6.32 ENSRNOT00000024460
Ipcef1
interaction protein for cytohesin exchange factors 1
chr10_-_62664466 6.24 ENSRNOT00000078730
Git1
GIT ArfGAP 1
chr13_+_92264231 5.54 ENSRNOT00000066509
ENSRNOT00000004716
Spta1
spectrin, alpha, erythrocytic 1
chr2_+_22950018 5.49 ENSRNOT00000071804
Homer1
homer scaffolding protein 1
chrX_+_111798233 5.45 ENSRNOT00000078582
Prps1
phosphoribosyl pyrophosphate synthetase 1
chr6_-_2961510 5.31 ENSRNOT00000090688
Dhx57
DExH-box helicase 57
chr2_+_186980992 5.22 ENSRNOT00000020717
Arhgef11
Rho guanine nucleotide exchange factor 11
chrX_+_106253355 4.71 ENSRNOT00000004252
LOC102552920
armadillo repeat-containing X-linked protein 5-like
chr15_-_95514259 4.69 ENSRNOT00000038433
Slitrk6
SLIT and NTRK-like family, member 6
chr8_-_119889661 4.69 ENSRNOT00000011780
Stac
SH3 and cysteine rich domain
chr14_+_69800156 4.63 ENSRNOT00000072746
Lcorl
ligand dependent nuclear receptor corepressor-like
chr12_-_17311112 4.30 ENSRNOT00000001732
Gper1
G protein-coupled estrogen receptor 1
chr19_-_54648227 4.13 ENSRNOT00000025424
Klhdc4
kelch domain containing 4
chr10_-_1744647 4.12 ENSRNOT00000081886
AABR07028997.1

chr10_-_52290657 4.09 ENSRNOT00000005293
Map2k4
mitogen activated protein kinase kinase 4
chr5_-_70463546 3.47 ENSRNOT00000043184
AC118841.1

chr18_+_14756684 3.34 ENSRNOT00000076085
ENSRNOT00000076129
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr4_-_165456677 3.03 ENSRNOT00000082207
Klra2
killer cell lectin-like receptor, subfamily A, member 2
chr4_-_28310178 2.98 ENSRNOT00000084021
RGD1563091
similar to OEF2
chr8_-_50277797 2.84 ENSRNOT00000082508
Pafah1b2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
chr2_+_186980793 2.83 ENSRNOT00000091336
Arhgef11
Rho guanine nucleotide exchange factor 11
chr10_-_64550145 2.81 ENSRNOT00000050232
Nxn
nucleoredoxin
chr10_-_34990943 2.74 ENSRNOT00000075555
Rmnd5b
required for meiotic nuclear division 5 homolog B
chr20_+_4363508 2.73 ENSRNOT00000077205
Ager
advanced glycosylation end product-specific receptor
chr3_-_72081079 2.72 ENSRNOT00000007914
Tmx2
thioredoxin-related transmembrane protein 2
chr5_+_58995249 2.70 ENSRNOT00000023411
Ccdc107
coiled-coil domain containing 107
chr18_-_81428971 2.63 ENSRNOT00000065201
Zfp407
zinc finger protein 407
chr17_+_34704616 2.46 ENSRNOT00000090706
ENSRNOT00000083674
ENSRNOT00000077110
Exoc2
exocyst complex component 2
chr8_+_18795525 2.34 ENSRNOT00000050430
Olr1124
olfactory receptor 1124
chr4_-_67301102 2.21 ENSRNOT00000034549
Dennd2a
DENN domain containing 2A
chr3_+_75265525 2.12 ENSRNOT00000013319
Olr554
olfactory receptor 554
chr11_+_74014983 2.11 ENSRNOT00000040884
NEWGENE_2724
glycoprotein V platelet
chr17_-_2705123 2.01 ENSRNOT00000024940
Olr1652
olfactory receptor 1652
chr12_-_23624212 1.88 ENSRNOT00000064405
ENSRNOT00000001943
Rasa4
RAS p21 protein activator 4
chr4_+_34237762 1.82 ENSRNOT00000084163
Mios
meiosis regulator for oocyte development
chr15_-_9086282 1.82 ENSRNOT00000008989
Thrb
thyroid hormone receptor beta
chr9_-_80295446 1.80 ENSRNOT00000023769
Tnp1
transition protein 1
chr11_-_43992598 1.79 ENSRNOT00000002260
Cldnd1
claudin domain containing 1
chr8_-_21481735 1.70 ENSRNOT00000038069
Zfp426
zinc finger protein 426
chr4_+_123760743 1.69 ENSRNOT00000013498
Ccdc174
coiled-coil domain containing 174
chr5_-_117612123 1.66 ENSRNOT00000065112
Dock7
dedicator of cytokinesis 7
chr1_-_172552099 1.64 ENSRNOT00000090373
Olr257
olfactory receptor 257
chr18_+_17550350 1.42 ENSRNOT00000078870
RGD1562608
similar to KIAA1328 protein
chr20_+_1647441 1.40 ENSRNOT00000000986
Olr1730
olfactory receptor 1730
chr5_-_155709215 1.37 ENSRNOT00000018118
Cdc42
cell division cycle 42
chrX_+_156210002 1.35 ENSRNOT00000077744
Olr1768
olfactory receptor 1768
chr1_+_60117804 1.19 ENSRNOT00000080437
Vom1r8
vomeronasal 1 receptor 8
chr1_+_167051209 1.18 ENSRNOT00000055249
Numa1
nuclear mitotic apparatus protein 1
chr4_+_129574264 1.15 ENSRNOT00000010185
Arl6ip5
ADP-ribosylation factor like GTPase 6 interacting protein 5
chr1_-_225948626 1.14 ENSRNOT00000077823
Incenp
inner centromere protein
chr5_+_135029955 1.11 ENSRNOT00000074860
LOC100911669
uncharacterized LOC100911669
chr10_+_35872619 1.03 ENSRNOT00000059190
Hnrnph1
heterogeneous nuclear ribonucleoprotein H1
chr3_+_148448732 1.03 ENSRNOT00000083812
Ttll9
tubulin tyrosine ligase like 9
chr8_+_117576788 0.98 ENSRNOT00000027584
Ip6k2
inositol hexakisphosphate kinase 2
chr8_-_70436028 0.98 ENSRNOT00000077152
Slc24a1
solute carrier family 24 member 1
chr18_+_60392376 0.80 ENSRNOT00000023890
Nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr4_+_44321883 0.79 ENSRNOT00000091095
Tes
testin LIM domain protein
chr7_+_132378273 0.79 ENSRNOT00000010990
LOC690142
hypothetical protein LOC690142
chr17_+_45199178 0.78 ENSRNOT00000080047
Zscan26
zinc finger and SCAN domain containing 26
chr10_+_71322145 0.54 ENSRNOT00000079418
Synrg
synergin, gamma
chr3_-_73124644 0.53 ENSRNOT00000012711
Olr455
olfactory receptor 455
chr1_-_60407295 0.49 ENSRNOT00000078350
Vom1r12
vomeronasal 1 receptor 12
chr4_+_88048267 0.39 ENSRNOT00000044913
Vom1r81
vomeronasal 1 receptor 81
chr2_+_226825635 0.36 ENSRNOT00000042173
AABR07013200.1

chr3_+_102841615 0.28 ENSRNOT00000075178
Olr770
olfactory receptor 770
chr3_-_76626605 0.18 ENSRNOT00000051292
Olr625
olfactory receptor 625
chr11_+_81757983 0.13 ENSRNOT00000088503
Tbccd1
TBCC domain containing 1
chr2_-_258932200 0.08 ENSRNOT00000045905
Adgrl2
adhesion G protein-coupled receptor L2
chr15_-_39742103 0.00 ENSRNOT00000074587
ENSRNOT00000036781
ENSRNOT00000071919
Setdb2
SET domain, bifurcated 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid5b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
3.8 11.4 GO:0071623 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
3.3 19.9 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
3.3 13.0 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.4 12.1 GO:1904045 cellular response to aldosterone(GO:1904045)
2.4 11.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
2.0 15.7 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.8 12.8 GO:0000103 sulfate assimilation(GO:0000103)
1.8 5.4 GO:0034418 urate biosynthetic process(GO:0034418)
1.7 11.6 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.4 4.3 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
1.4 10.0 GO:0048496 maintenance of organ identity(GO:0048496)
1.2 8.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.0 4.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.9 4.7 GO:0060005 vestibular reflex(GO:0060005)
0.9 2.7 GO:0072714 response to selenite ion(GO:0072714) negative regulation of connective tissue replacement(GO:1905204)
0.8 8.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.8 13.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.7 8.1 GO:0006108 malate metabolic process(GO:0006108)
0.6 13.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.6 9.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.6 7.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.5 1.4 GO:0071338 submandibular salivary gland formation(GO:0060661) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 7.6 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.4 3.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.4 1.7 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.4 17.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.4 9.3 GO:0045475 locomotor rhythm(GO:0045475)
0.4 2.5 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.3 6.2 GO:0001771 immunological synapse formation(GO:0001771)
0.3 1.8 GO:0008050 female courtship behavior(GO:0008050)
0.3 9.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.3 8.6 GO:0048679 regulation of collateral sprouting(GO:0048670) regulation of axon regeneration(GO:0048679)
0.3 1.8 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.2 7.9 GO:0015701 bicarbonate transport(GO:0015701)
0.2 1.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.2 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 5.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 8.5 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.2 10.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 4.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 14.3 GO:0007416 synapse assembly(GO:0007416)
0.1 5.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 11.7 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 1.2 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 1.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 8.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 2.8 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 1.0 GO:0006817 phosphate ion transport(GO:0006817)
0.0 1.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:0098855 HCN channel complex(GO:0098855)
2.9 11.6 GO:0031088 platelet dense granule membrane(GO:0031088)
1.9 9.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
1.7 10.0 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
1.6 15.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.1 5.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.7 2.7 GO:0034657 GID complex(GO:0034657)
0.6 5.5 GO:0008091 spectrin(GO:0008091) spectrin-associated cytoskeleton(GO:0014731) cuticular plate(GO:0032437)
0.4 1.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.4 4.3 GO:0044327 dendritic spine head(GO:0044327)
0.3 11.8 GO:0008305 integrin complex(GO:0008305)
0.3 9.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 1.8 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.4 GO:0000322 storage vacuole(GO:0000322)
0.2 17.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.5 GO:0043034 costamere(GO:0043034)
0.1 4.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 3.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.5 GO:0000145 exocyst(GO:0000145)
0.1 8.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.1 GO:0000801 central element(GO:0000801)
0.1 7.8 GO:0042734 presynaptic membrane(GO:0042734)
0.1 13.0 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 10.0 GO:0005795 Golgi stack(GO:0005795)
0.1 1.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 8.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 18.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.7 GO:0030315 T-tubule(GO:0030315)
0.1 10.6 GO:0043204 perikaryon(GO:0043204)
0.1 15.1 GO:0016324 apical plasma membrane(GO:0016324)
0.1 1.0 GO:0019013 viral nucleocapsid(GO:0019013)
0.1 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 7.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 8.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 20.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 7.0 GO:0005925 focal adhesion(GO:0005925)
0.0 2.7 GO:0005769 early endosome(GO:0005769)
0.0 28.7 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
4.5 13.4 GO:0019807 aspartoacylase activity(GO:0019807)
4.3 12.8 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
3.9 15.7 GO:0070699 type II activin receptor binding(GO:0070699)
2.9 11.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
2.8 11.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
2.3 9.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
2.0 8.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.0 7.8 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.4 19.9 GO:0016805 dipeptidase activity(GO:0016805)
1.4 8.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.2 12.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.2 8.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.1 5.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.1 9.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.9 8.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.8 13.0 GO:0035198 miRNA binding(GO:0035198)
0.7 2.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.7 5.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.5 2.7 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.5 1.4 GO:0032427 GBD domain binding(GO:0032427)
0.4 4.3 GO:1990239 estrogen receptor activity(GO:0030284) steroid hormone binding(GO:1990239)
0.3 4.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 1.0 GO:0052723 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 7.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 2.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 9.3 GO:0070888 E-box binding(GO:0070888)
0.2 7.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 5.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 2.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 10.0 GO:0017022 myosin binding(GO:0017022)
0.1 11.7 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 10.6 GO:0008013 beta-catenin binding(GO:0008013)
0.1 11.8 GO:0005178 integrin binding(GO:0005178)
0.1 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 8.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 5.3 GO:0004386 helicase activity(GO:0004386)
0.0 8.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 12.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 7.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.3 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 11.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.4 6.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 13.5 ST GA13 PATHWAY G alpha 13 Pathway
0.3 11.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 6.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 9.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.5 PID INSULIN PATHWAY Insulin Pathway
0.0 1.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 12.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.6 11.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.6 15.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 9.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.4 7.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 9.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 5.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 11.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 12.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 1.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 8.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 10.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 5.4 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase