ISMARA results: Arntl_Tfe3_Mlx_Mitf_Mlxipl

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

Z-value: 1.09

Motif logo

Transcription factors associated with Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

Gene Symbol	Gene ID	Gene Info
Arntl NCBI RGD Ensembl	ENSRNOG00000014448	aryl hydrocarbon receptor nuclear translocator-like
Tfe3 NCBI RGD Ensembl	ENSRNOG00000009605	transcription factor binding to IGHM enhancer 3
Mlx NCBI RGD Ensembl	ENSRNOG00000019983	MLX, MAX dimerization protein
Mitf NCBI RGD Ensembl	ENSRNOG00000008658	melanogenesis associated transcription factor
Mlxipl NCBI RGD Ensembl	ENSRNOG00000046171	Mlxipl
Tfec NCBI RGD Ensembl	ENSRNOG00000061595	transcription factor EC

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Arntl	rn6_v1_chr1_+_178039063_178039063	-0.31	8.9e-09	Click!
Mitf	rn6_v1_chr4_+_130172727_130172727	-0.30	7.0e-08	Click!
Tfe3	rn6_v1_chrX_-_15587419_15587419	-0.29	1.4e-07	Click!
Mlx	rn6_v1_chr10_+_88997399_88997399	-0.07	2.0e-01	Click!
Tfec	rn6_v1_chr4_-_44136815_44136815	0.03	5.7e-01	Click!

Activity profile of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec motif

Sorted Z-values of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_243550627 Show fit	56.81	ENSRNOT00000085067 ENSRNOT00000083682	Adh1 NCBI RGD Ensembl Show fit	alcohol dehydrogenase 1 (class I)
chr12_+_24367199 Show fit	50.95	ENSRNOT00000001971	Fkbp6 NCBI RGD Ensembl Show fit	FK506 binding protein 6
chr13_+_105408179 Show fit	50.17	ENSRNOT00000003378	Ddx3y NCBI RGD Ensembl Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr2_+_189106039 Show fit	47.87	ENSRNOT00000028210	Ube2q1 NCBI RGD Ensembl Show fit	ubiquitin conjugating enzyme E2 Q1
chr1_+_102849889 Show fit	47.32	ENSRNOT00000066791	Gtf2h1 NCBI RGD Ensembl Show fit	general transcription factor IIH subunit 1
chr13_+_89597138 Show fit	44.60	ENSRNOT00000004662	Apoa2 NCBI RGD Ensembl Show fit	apolipoprotein A2
chr5_+_138470069 Show fit	41.67	ENSRNOT00000076343 ENSRNOT00000064073	Zmynd12 NCBI RGD Ensembl Show fit	zinc finger, MYND-type containing 12
chr3_-_94686989 Show fit	41.12	ENSRNOT00000016677	Depdc7 NCBI RGD Ensembl Show fit	DEP domain containing 7
chr19_+_52225582 Show fit	40.15	ENSRNOT00000020917	Dnaaf1 NCBI RGD Ensembl Show fit	dynein, axonemal, assembly factor 1
chr14_-_3462629 Show fit	38.16	ENSRNOT00000061538	Brdt NCBI RGD Ensembl Show fit	bromodomain testis associated
chr3_+_114176309 Show fit	38.03	ENSRNOT00000023350	Sord NCBI RGD Ensembl Show fit	sorbitol dehydrogenase
chr1_-_88111293 Show fit	35.35	ENSRNOT00000077195	Spred3 NCBI RGD Ensembl Show fit	sprouty-related, EVH1 domain containing 3
chr16_-_81706664 Show fit	35.20	ENSRNOT00000026580	Lamp1 NCBI RGD Ensembl Show fit	lysosomal-associated membrane protein 1
chr5_+_124300477 Show fit	33.14	ENSRNOT00000010100	C8b NCBI RGD Ensembl Show fit	complement C8 beta chain
chr9_+_12633990 Show fit	32.99	ENSRNOT00000066517 ENSRNOT00000077532	Dazl NCBI RGD Ensembl Show fit	deleted in azoospermia-like
chr7_+_144628120 Show fit	31.11	ENSRNOT00000022247	Hoxc5 NCBI RGD Ensembl Show fit	homeo box C5
chr1_-_101773508 Show fit	30.72	ENSRNOT00000067430	Sult2b1 NCBI RGD Ensembl Show fit	sulfotransferase family 2B member 1
chr1_+_261229347 Show fit	30.72	ENSRNOT00000018485	Ubtd1 NCBI RGD Ensembl Show fit	ubiquitin domain containing 1
chr2_+_189400696 Show fit	30.54	ENSRNOT00000046919 ENSRNOT00000089801	LOC361985 NCBI RGD Ensembl Show fit	similar to NICE-3
chr9_+_71398710 Show fit	29.82	ENSRNOT00000049411	Ccnyl1 NCBI RGD Ensembl Show fit	cyclin Y-like 1
chr8_-_113689681 Show fit	29.20	ENSRNOT00000056435	LOC688828 NCBI RGD Ensembl Show fit	similar to Nucleoside diphosphate-linked moiety X motif 16 (Nudix motif 16)
chr17_+_85356042 Show fit	28.95	ENSRNOT00000022201	Commd3 NCBI RGD Ensembl Show fit	COMM domain containing 3
chr10_+_14216155 Show fit	28.82	ENSRNOT00000020192	Hagh NCBI RGD Ensembl Show fit	hydroxyacyl glutathione hydrolase
chr16_+_68586235 Show fit	27.45	ENSRNOT00000039592	LOC103693984 NCBI RGD Ensembl Show fit	uncharacterized LOC103693984
chr10_+_84135116 Show fit	27.13	ENSRNOT00000031035	Hoxb7 NCBI RGD Ensembl Show fit	homeo box B7
chr10_+_56546710 Show fit	26.70	ENSRNOT00000023003	Ybx2 NCBI RGD Ensembl Show fit	Y box binding protein 2
chr10_+_109852036 Show fit	26.28	ENSRNOT00000054944	Aspscr1 NCBI RGD Ensembl Show fit	ASPSCR1, UBX domain containing tether for SLC2A4
chr1_+_263554453 Show fit	25.61	ENSRNOT00000070861	Abcc2 NCBI RGD Ensembl Show fit	ATP binding cassette subfamily C member 2
chr5_+_147535525 Show fit	25.58	ENSRNOT00000074628	Zbtb8os NCBI RGD Ensembl Show fit	zinc finger and BTB domain containing 8 opposite strand
chr10_+_90984227 Show fit	25.34	ENSRNOT00000003890 ENSRNOT00000093707	Ccdc103 NCBI RGD Ensembl Show fit	coiled-coil domain containing 103
chr20_-_32115310 Show fit	24.95	ENSRNOT00000067883 ENSRNOT00000081916	Vps26a NCBI RGD Ensembl Show fit	VPS26 retromer complex component A
chr15_-_39606003 Show fit	24.81	ENSRNOT00000059490	RGD1563302 NCBI RGD Ensembl Show fit	RGD1563302
chr20_+_46250363 Show fit	24.06	ENSRNOT00000076522 ENSRNOT00000000334	Cd164 NCBI RGD Ensembl Show fit	CD164 molecule
chr9_+_10172832 Show fit	23.90	ENSRNOT00000074555	Acsbg2 NCBI RGD Ensembl Show fit	acyl-CoA synthetase bubblegum family member 2
chr1_+_154377447 Show fit	23.77	ENSRNOT00000084268 ENSRNOT00000092086 ENSRNOT00000091470 ENSRNOT00000025415	Picalm NCBI RGD Ensembl Show fit	phosphatidylinositol binding clathrin assembly protein
chr2_+_93803449 Show fit	23.72	ENSRNOT00000014949	Fabp9 NCBI RGD Ensembl Show fit	fatty acid binding protein 9
chr4_-_50200328 Show fit	23.71	ENSRNOT00000060530	Aass NCBI RGD Ensembl Show fit	aminoadipate-semialdehyde synthase
chr12_-_48365784 Show fit	23.28	ENSRNOT00000077317	Dao NCBI RGD Ensembl Show fit	D-amino-acid oxidase
chr11_+_61531416 Show fit	22.68	ENSRNOT00000093263	Atp6v1a NCBI RGD Ensembl Show fit	ATPase H+ transporting V1 subunit A
chr1_+_154377247 Show fit	22.63	ENSRNOT00000092945	Picalm NCBI RGD Ensembl Show fit	phosphatidylinositol binding clathrin assembly protein
chr8_-_132790778 Show fit	22.32	ENSRNOT00000008255 ENSRNOT00000091431	Lztfl1 NCBI RGD Ensembl Show fit	leucine zipper transcription factor-like 1
chr10_+_109851854 Show fit	22.24	ENSRNOT00000087005	Aspscr1 NCBI RGD Ensembl Show fit	ASPSCR1, UBX domain containing tether for SLC2A4
chr10_-_87578854 Show fit	21.84	ENSRNOT00000065619	LOC680160 NCBI RGD Ensembl Show fit	similar to keratin associated protein 4-7
chr4_-_100099517 Show fit	21.44	ENSRNOT00000014277	Atoh8 NCBI RGD Ensembl Show fit	atonal bHLH transcription factor 8
chr2_-_195935878 Show fit	21.34	ENSRNOT00000028440	Cgn NCBI RGD Ensembl Show fit	cingulin
chr2_-_189400323 Show fit	21.06	ENSRNOT00000024364	Ubap2l NCBI RGD Ensembl Show fit	ubiquitin associated protein 2-like
chr14_+_85871597 Show fit	20.92	ENSRNOT00000079671	Ankrd36 NCBI RGD Ensembl Show fit	ankyrin repeat domain 36
chr14_-_19072677 Show fit	20.86	ENSRNOT00000060548	LOC360919 NCBI RGD Ensembl Show fit	similar to alpha-fetoprotein
chr1_+_65576535 Show fit	20.71	ENSRNOT00000026575	Slc27a5 NCBI RGD Ensembl Show fit	solute carrier family 27 member 5
chr3_+_161298962 Show fit	20.46	ENSRNOT00000066028	Ctsa NCBI RGD Ensembl Show fit	cathepsin A
chr10_+_4951557 Show fit	20.24	ENSRNOT00000003451	Prm3 NCBI RGD Ensembl Show fit	protamine 3
chr8_-_123371257 Show fit	20.19	ENSRNOT00000017243	Stt3b NCBI RGD Ensembl Show fit	STT3B, catalytic subunit of the oligosaccharyltransferase complex
chr8_-_36760742 Show fit	20.13	ENSRNOT00000017307	Ddx25 NCBI RGD Ensembl Show fit	DEAD-box helicase 25
chr1_+_21525421 Show fit	20.09	ENSRNOT00000017911	Arg1 NCBI RGD Ensembl Show fit	arginase 1
chr6_-_129010271 Show fit	19.92	ENSRNOT00000075378	Serpina10 NCBI RGD Ensembl Show fit	serpin family A member 10
chr1_+_222907159 Show fit	19.74	ENSRNOT00000032123	Hrasls5 NCBI RGD Ensembl Show fit	HRAS-like suppressor family, member 5
chr16_+_74865516 Show fit	19.59	ENSRNOT00000058072	Atp7b NCBI RGD Ensembl Show fit	ATPase copper transporting beta
chr9_+_82345719 Show fit	19.09	ENSRNOT00000057330 ENSRNOT00000078260	Fam134a NCBI RGD Ensembl Show fit	family with sequence similarity 134, member A
chr5_-_147784311 Show fit	18.97	ENSRNOT00000074172	Fam167b NCBI RGD Ensembl Show fit	family with sequence similarity 167, member B
chr9_+_100281339 Show fit	18.90	ENSRNOT00000029127	Agxt NCBI RGD Ensembl Show fit	alanine-glyoxylate aminotransferase
chr1_-_22625204 Show fit	18.72	ENSRNOT00000021694	Vnn1 NCBI RGD Ensembl Show fit	vanin 1
chr9_+_80118029 Show fit	18.66	ENSRNOT00000023068	Igfbp2 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 2
chr12_+_19599834 Show fit	18.46	ENSRNOT00000092039 ENSRNOT00000042006	Stag3 NCBI RGD Ensembl Show fit	stromal antigen 3
chr5_+_73496027 Show fit	18.19	ENSRNOT00000022395	Actl7a NCBI RGD Ensembl Show fit	actin-like 7a
chr3_+_61613774 Show fit	17.99	ENSRNOT00000002148	Hoxd10 NCBI RGD Ensembl Show fit	homeo box D10
chr17_+_76306585 Show fit	17.90	ENSRNOT00000065978	Dhtkd1 NCBI RGD Ensembl Show fit	dehydrogenase E1 and transketolase domain containing 1
chr2_-_182038178 Show fit	17.74	ENSRNOT00000040708	Fgb NCBI RGD Ensembl Show fit	fibrinogen beta chain
chr13_+_84474319 Show fit	17.70	ENSRNOT00000031367 ENSRNOT00000072244 ENSRNOT00000072897 ENSRNOT00000064168 ENSRNOT00000074954 ENSRNOT00000073696	Ildr2 NCBI RGD Ensembl Show fit	immunoglobulin-like domain containing receptor 2
chr19_+_26106838 Show fit	17.64	ENSRNOT00000035987	Hook2 NCBI RGD Ensembl Show fit	hook microtubule-tethering protein 2
chr7_+_143096874 Show fit	17.62	ENSRNOT00000010881	RGD1305207 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 1700011A15
chr9_-_43251400 Show fit	17.60	ENSRNOT00000037570	Fam178b NCBI RGD Ensembl Show fit	family with sequence similarity 178, member B
chr7_+_11414446 Show fit	17.47	ENSRNOT00000027441	Pias4 NCBI RGD Ensembl Show fit	protein inhibitor of activated STAT, 4
chr13_-_101163393 Show fit	17.41	ENSRNOT00000037997	Ccdc185 NCBI RGD Ensembl Show fit	coiled-coil domain containing 185
chr12_+_24158766 Show fit	17.18	ENSRNOT00000001963	Ccl26 NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 26
chr18_+_69841053 Show fit	17.18	ENSRNOT00000071545 ENSRNOT00000030613 ENSRNOT00000075543	Mro NCBI RGD Ensembl Show fit	maestro
chr12_+_41600005 Show fit	17.15	ENSRNOT00000001872	Plbd2 NCBI RGD Ensembl Show fit	phospholipase B domain containing 2
chr1_-_252100759 Show fit	17.10	ENSRNOT00000028098	Rnls NCBI RGD Ensembl Show fit	renalase, FAD-dependent amine oxidase
chr6_-_26820959 Show fit	16.99	ENSRNOT00000043572	Khk NCBI RGD Ensembl Show fit	ketohexokinase
chr19_-_25961666 Show fit	16.86	ENSRNOT00000004091	Calr NCBI RGD Ensembl Show fit	calreticulin
chr4_-_82141385 Show fit	16.77	ENSRNOT00000008447	Hoxa3 NCBI RGD Ensembl Show fit	homeobox A3
chr19_+_58505811 Show fit	16.55	ENSRNOT00000031717	Map10 NCBI RGD Ensembl Show fit	microtubule-associated protein 10
chr3_-_8852192 Show fit	16.53	ENSRNOT00000022786	Dolk NCBI RGD Ensembl Show fit	dolichol kinase
chr12_+_16912249 Show fit	16.38	ENSRNOT00000085936	Tmem184a NCBI RGD Ensembl Show fit	transmembrane protein 184A
chr7_-_130451283 Show fit	16.35	ENSRNOT00000017783	Arsa NCBI RGD Ensembl Show fit	arylsulfatase A
chr8_-_115981910 Show fit	16.14	ENSRNOT00000019867	Dock3 NCBI RGD Ensembl Show fit	dedicator of cyto-kinesis 3
chr11_-_34598102 Show fit	16.08	ENSRNOT00000068743	Pigp NCBI RGD Ensembl Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_102849430 Show fit	15.98	ENSRNOT00000086856	Saa4 NCBI RGD Ensembl Show fit	serum amyloid A4
chr3_-_148428494 Show fit	15.81	ENSRNOT00000011350	Dusp15 NCBI RGD Ensembl Show fit	dual specificity phosphatase 15
chr4_-_82271893 Show fit	15.76	ENSRNOT00000075005	Hoxa7 NCBI RGD Ensembl Show fit	homeobox A7
chr9_-_27447877 Show fit	15.65	ENSRNOT00000085195	Gsta1 NCBI RGD Ensembl Show fit	glutathione S-transferase alpha 1
chr4_+_57926531 Show fit	15.64	ENSRNOT00000013948	Cpa5 NCBI RGD Ensembl Show fit	carboxypeptidase A5
chr10_+_59765258 Show fit	15.61	ENSRNOT00000026351	Shpk NCBI RGD Ensembl Show fit	sedoheptulokinase
chrX_+_74497262 Show fit	15.54	ENSRNOT00000003899	Zcchc13 NCBI RGD Ensembl Show fit	zinc finger CCHC-type containing 13
chr11_+_61531571 Show fit	15.45	ENSRNOT00000093467 ENSRNOT00000002727	Atp6v1a NCBI RGD Ensembl Show fit	ATPase H+ transporting V1 subunit A
chr15_-_39573776 Show fit	15.37	ENSRNOT00000082517	LOC691850 NCBI RGD Ensembl Show fit	hypothetical protein LOC691850
chr13_-_91427575 Show fit	15.25	ENSRNOT00000012092	Apcs NCBI RGD Ensembl Show fit	amyloid P component, serum
chr1_-_197997664 Show fit	15.16	ENSRNOT00000025898	Cln3 NCBI RGD Ensembl Show fit	ceroid-lipofuscinosis, neuronal 3
chr8_-_23014499 Show fit	15.15	ENSRNOT00000017820	Ccdc151 NCBI RGD Ensembl Show fit	coiled-coil domain containing 151
chr5_+_171242897 Show fit	15.02	ENSRNOT00000032859	RGD1304567 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA A430005L14
chr13_-_74005486 Show fit	14.79	ENSRNOT00000090173	AABR07021465.1 NCBI RGD Ensembl Show fit
chr16_-_47163898 Show fit	14.60	ENSRNOT00000074490	Ccdc110 NCBI RGD Ensembl Show fit	coiled-coil domain containing 110
chr5_-_58163584 Show fit	14.60	ENSRNOT00000060594	Ccl27 NCBI RGD Ensembl Show fit	C-C motif chemokine ligand 27
chr9_-_50820290 Show fit	14.53	ENSRNOT00000050748	LOC102548013 NCBI RGD Ensembl Show fit	uncharacterized LOC102548013
chr18_+_55797198 Show fit	14.27	ENSRNOT00000026334 ENSRNOT00000026394	Dctn4 NCBI RGD Ensembl Show fit	dynactin subunit 4
chr8_-_111107599 Show fit	14.25	ENSRNOT00000031313	Cep63 NCBI RGD Ensembl Show fit	centrosomal protein 63
chr2_+_127538659 Show fit	14.16	ENSRNOT00000093483 ENSRNOT00000058476	Slc25a31 NCBI RGD Ensembl Show fit	solute carrier family 25 member 31
chr2_+_114423533 Show fit	14.14	ENSRNOT00000091221	Slc2a2 NCBI RGD Ensembl Show fit	solute carrier family 2 member 2
chr14_-_89238094 Show fit	14.14	ENSRNOT00000006818	Sun3 NCBI RGD Ensembl Show fit	Sad1 and UNC84 domain containing 3
chr8_+_64325435 Show fit	14.07	ENSRNOT00000013747	Hexa NCBI RGD Ensembl Show fit	hexosaminidase subunit alpha
chr13_+_109646455 Show fit	14.01	ENSRNOT00000073985	LOC498316 NCBI RGD Ensembl Show fit	hypothetical LOC498316
chr3_+_61604672 Show fit	13.92	ENSRNOT00000080456	Hoxd11 NCBI RGD Ensembl Show fit	homeobox D11
chr16_+_8497569 Show fit	13.86	ENSRNOT00000027054	Ogdhl NCBI RGD Ensembl Show fit	oxoglutarate dehydrogenase-like
chr9_-_10170428 Show fit	13.81	ENSRNOT00000073048	LOC316124 NCBI RGD Ensembl Show fit	similar to gonadotropin-regulated long chain acyl-CoA synthetase
chr5_-_32956159 Show fit	13.80	ENSRNOT00000078264	Cnbd1 NCBI RGD Ensembl Show fit	cyclic nucleotide binding domain containing 1
chr5_-_104920906 Show fit	13.77	ENSRNOT00000071318	Fam154a NCBI RGD Ensembl Show fit	family with sequence similarity 154, member A
chr7_-_120559157 Show fit	13.75	ENSRNOT00000090565 ENSRNOT00000016827 ENSRNOT00000017108	Pla2g6 NCBI RGD Ensembl Show fit	phospholipase A2 group VI
chr9_-_100624638 Show fit	13.71	ENSRNOT00000051155	Hdlbp NCBI RGD Ensembl Show fit	high density lipoprotein binding protein
chrX_+_13992064 Show fit	13.70	ENSRNOT00000036543	LOC100363125 NCBI RGD Ensembl Show fit	rCG42854-like
chr11_+_74057361 Show fit	13.69	ENSRNOT00000048746	Cpn2 NCBI RGD Ensembl Show fit	carboxypeptidase N subunit 2
chr3_-_33075685 Show fit	13.62	ENSRNOT00000006937	Orc4 NCBI RGD Ensembl Show fit	origin recognition complex, subunit 4
chr10_-_35058870 Show fit	13.60	ENSRNOT00000079481	AABR07029573.3 NCBI RGD Ensembl Show fit
chr17_-_43584152 Show fit	13.51	ENSRNOT00000023241	Slc17a2 NCBI RGD Ensembl Show fit	solute carrier family 17, member 2
chr18_-_37245809 Show fit	13.49	ENSRNOT00000079585	Ppp2r2b NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B, beta
chr3_+_163570532 Show fit	13.48	ENSRNOT00000010054	Arfgef2 NCBI RGD Ensembl Show fit	ADP ribosylation factor guanine nucleotide exchange factor 2
chr12_-_21832813 Show fit	13.42	ENSRNOT00000075280	Cldn3 NCBI RGD Ensembl Show fit	claudin 3
chr8_-_85645718 Show fit	13.39	ENSRNOT00000032185	Gsta2 NCBI RGD Ensembl Show fit	glutathione S-transferase alpha 2
chr10_+_65780494 Show fit	13.39	ENSRNOT00000013100	Poldip2 NCBI RGD Ensembl Show fit	DNA polymerase delta interacting protein 2
chr17_-_417480 Show fit	13.36	ENSRNOT00000023685	Fbp1 NCBI RGD Ensembl Show fit	fructose-bisphosphatase 1
chr1_-_80599572 Show fit	13.31	ENSRNOT00000024832	Apoc4 NCBI RGD Ensembl Show fit	apolipoprotein C4
chr19_+_52077501 Show fit	13.27	ENSRNOT00000079240	Osgin1 NCBI RGD Ensembl Show fit	oxidative stress induced growth inhibitor 1
chr10_+_10725819 Show fit	13.24	ENSRNOT00000004159	Glyr1 NCBI RGD Ensembl Show fit	glyoxylate reductase 1 homolog
chr3_+_171597241 Show fit	13.19	ENSRNOT00000029558	LOC689618 NCBI RGD Ensembl Show fit	similar to Protein C20orf85 homolog
chr1_-_250951697 Show fit	13.11	ENSRNOT00000054761	Sgms1 NCBI RGD Ensembl Show fit	sphingomyelin synthase 1
chr2_-_187622373 Show fit	12.99	ENSRNOT00000026396	Rhbg NCBI RGD Ensembl Show fit	Rh family B glycoprotein
chr10_-_44746549 Show fit	12.87	ENSRNOT00000003841	Fam183b NCBI RGD Ensembl Show fit	family with sequence similarity 183, member B
chr4_+_148286858 Show fit	12.75	ENSRNOT00000017294 ENSRNOT00000092294 ENSRNOT00000092477	March8 NCBI RGD Ensembl Show fit	membrane associated ring-CH-type finger 8
chr2_-_211017778 Show fit	12.68	ENSRNOT00000026883	Sypl2 NCBI RGD Ensembl Show fit	synaptophysin-like 2
chr14_+_22724070 Show fit	12.65	ENSRNOT00000089471	Ugt2b10 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide B10
chr11_-_34598275 Show fit	12.58	ENSRNOT00000077233	Pigp NCBI RGD Ensembl Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr1_+_196737627 Show fit	12.56	ENSRNOT00000066652	LOC100271845 NCBI RGD Ensembl Show fit	hypothetical protein LOC100271845
chr2_+_208541361 Show fit	12.44	ENSRNOT00000021288	Tmigd3 NCBI RGD Ensembl Show fit	transmembrane and immunoglobulin domain containing 3
chr12_+_37593874 Show fit	12.42	ENSRNOT00000057902	Sbno1 NCBI RGD Ensembl Show fit	strawberry notch homolog 1
chr17_+_54280851 Show fit	12.41	ENSRNOT00000024022	Arhgap12 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 12
chr2_+_147006830 Show fit	12.36	ENSRNOT00000080780	AABR07010672.1 NCBI RGD Ensembl Show fit
chrX_-_106558366 Show fit	12.25	ENSRNOT00000042126	Bex2 NCBI RGD Ensembl Show fit	brain expressed X-linked 2
chr7_+_94130852 Show fit	12.22	ENSRNOT00000011485	Mal2 NCBI RGD Ensembl Show fit	mal, T-cell differentiation protein 2
chrX_+_74200972 Show fit	12.18	ENSRNOT00000076956	Chic1 NCBI RGD Ensembl Show fit	cysteine-rich hydrophobic domain 1
chr7_+_38945836 Show fit	12.18	ENSRNOT00000006455	Ccer1 NCBI RGD Ensembl Show fit	coiled-coil glutamate-rich protein 1
chr17_-_9837293 Show fit	12.14	ENSRNOT00000091320 ENSRNOT00000022134	Prelid1 NCBI RGD Ensembl Show fit	PRELI domain containing 1
chr3_+_61658245 Show fit	12.14	ENSRNOT00000033511	Hoxd3 NCBI RGD Ensembl Show fit	homeo box D3
chr10_+_40543288 Show fit	12.13	ENSRNOT00000016755	Slc36a1 NCBI RGD Ensembl Show fit	solute carrier family 36 member 1
chr19_-_42180362 Show fit	12.11	ENSRNOT00000089515	Pmfbp1 NCBI RGD Ensembl Show fit	polyamine modulated factor 1 binding protein 1
chr15_+_28319136 Show fit	12.10	ENSRNOT00000048723	Tppp2 NCBI RGD Ensembl Show fit	tubulin polymerization-promoting protein family member 2
chr7_+_70980422 Show fit	12.05	ENSRNOT00000077912	Rdh16 NCBI RGD Ensembl Show fit	retinol dehydrogenase 16 (all-trans)
chr10_-_94988461 Show fit	12.01	ENSRNOT00000048490	Ddx5 NCBI RGD Ensembl Show fit	DEAD-box helicase 5
chr7_-_120558805 Show fit	11.99	ENSRNOT00000087344	Pla2g6 NCBI RGD Ensembl Show fit	phospholipase A2 group VI
chr1_+_188288738 Show fit	11.92	ENSRNOT00000055103	Tmc5 NCBI RGD Ensembl Show fit	transmembrane channel-like 5
chr13_+_70852023 Show fit	11.90	ENSRNOT00000003661	Shcbp1l NCBI RGD Ensembl Show fit	SHC binding and spindle associated 1 like
chr1_-_48559162 Show fit	11.86	ENSRNOT00000080352	Plg NCBI RGD Ensembl Show fit	plasminogen
chr2_+_243820661 Show fit	11.80	ENSRNOT00000090526	Eif4e NCBI RGD Ensembl Show fit	eukaryotic translation initiation factor 4E
chr14_-_10446909 Show fit	11.78	ENSRNOT00000002962	Mrps18c NCBI RGD Ensembl Show fit	mitochondrial ribosomal protein S18C
chr19_-_37370429 Show fit	11.70	ENSRNOT00000022497	Kctd19 NCBI RGD Ensembl Show fit	potassium channel tetramerization domain containing 19
chr2_-_60683451 Show fit	11.70	ENSRNOT00000046215	Rai14 NCBI RGD Ensembl Show fit	retinoic acid induced 14
chr1_-_259287684 Show fit	11.67	ENSRNOT00000054724	Cyp2c22 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 22
chr19_-_10826895 Show fit	11.59	ENSRNOT00000090217	Rspry1 NCBI RGD Ensembl Show fit	ring finger and SPRY domain containing 1
chr1_-_91462603 Show fit	11.58	ENSRNOT00000015384	Lrp3 NCBI RGD Ensembl Show fit	LDL receptor related protein 3
chr13_+_99335020 Show fit	11.49	ENSRNOT00000029787	AABR07021930.1 NCBI RGD Ensembl Show fit
chrX_-_54303729 Show fit	11.49	ENSRNOT00000087919 ENSRNOT00000064340 ENSRNOT00000051249 ENSRNOT00000087547	Gk NCBI RGD Ensembl Show fit	glycerol kinase
chr17_+_45175121 Show fit	11.37	ENSRNOT00000080417	Nkapl NCBI RGD Ensembl Show fit	NFKB activating protein-like
chr6_+_52702544 Show fit	11.36	ENSRNOT00000014252	Efcab10 NCBI RGD Ensembl Show fit	EF-hand calcium binding domain 10
chr14_-_44767120 Show fit	11.25	ENSRNOT00000003991	Wdr19 NCBI RGD Ensembl Show fit	WD repeat domain 19
chr17_+_78793336 Show fit	11.18	ENSRNOT00000057898	Mt1 NCBI RGD Ensembl Show fit	metallothionein 1
chr7_-_120874308 Show fit	11.09	ENSRNOT00000078320	Fam227a NCBI RGD Ensembl Show fit	family with sequence similarity 227, member A
chr3_+_79678201 Show fit	11.09	ENSRNOT00000087604 ENSRNOT00000079709	Mtch2 NCBI RGD Ensembl Show fit	mitochondrial carrier 2
chr10_-_6870011 Show fit	11.05	ENSRNOT00000003439	RGD1309748 NCBI RGD Ensembl Show fit	similar to CG4768-PA
chr10_+_93305969 Show fit	11.05	ENSRNOT00000008019	Efcab3 NCBI RGD Ensembl Show fit	EF-hand calcium binding domain 3
chr12_+_37594185 Show fit	10.98	ENSRNOT00000088787	Sbno1 NCBI RGD Ensembl Show fit	strawberry notch homolog 1
chr10_+_71202456 Show fit	10.96	ENSRNOT00000076893	Hnf1b NCBI RGD Ensembl Show fit	HNF1 homeobox B
chr1_-_54748763 Show fit	10.94	ENSRNOT00000074549	LOC100911027 NCBI RGD Ensembl Show fit	protein MAL2-like
chr11_-_81444375 Show fit	10.91	ENSRNOT00000058479 ENSRNOT00000078131 ENSRNOT00000080949 ENSRNOT00000080562 ENSRNOT00000084867	Kng1 NCBI RGD Ensembl Show fit	kininogen 1
chr17_+_16333415 Show fit	10.91	ENSRNOT00000060550	Ptpdc1 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase domain containing 1
chr5_-_9429859 Show fit	10.82	ENSRNOT00000009462	Adhfe1 NCBI RGD Ensembl Show fit	alcohol dehydrogenase, iron containing, 1
chr19_+_52077109 Show fit	10.82	ENSRNOT00000020225	Osgin1 NCBI RGD Ensembl Show fit	oxidative stress induced growth inhibitor 1
chrX_-_105308554 Show fit	10.78	ENSRNOT00000045556	Taf7l NCBI RGD Ensembl Show fit	TATA-box binding protein associated factor 7-like
chr2_+_60337667 Show fit	10.76	ENSRNOT00000024035	Agxt2 NCBI RGD Ensembl Show fit	alanine-glyoxylate aminotransferase 2
chr5_+_133896141 Show fit	10.75	ENSRNOT00000011434	Pdzk1ip1 NCBI RGD Ensembl Show fit	PDZK1 interacting protein 1
chr2_-_173563273 Show fit	10.74	ENSRNOT00000081423	Zbbx NCBI RGD Ensembl Show fit	zinc finger, B-box domain containing
chr10_+_97647111 Show fit	10.73	ENSRNOT00000055062	Gna13 NCBI RGD Ensembl Show fit	G protein subunit alpha 13
chrX_-_105793306 Show fit	10.73	ENSRNOT00000015806	Nxf2 NCBI RGD Ensembl Show fit	nuclear RNA export factor 2
chr9_-_80295446 Show fit	10.65	ENSRNOT00000023769	Tnp1 NCBI RGD Ensembl Show fit	transition protein 1
chr11_+_52828116 Show fit	10.60	ENSRNOT00000035340	Ccdc54 NCBI RGD Ensembl Show fit	coiled-coil domain containing 54
chr1_+_100086520 Show fit	10.60	ENSRNOT00000025723	Klk1 NCBI RGD Ensembl Show fit	kallikrein 1
chr14_+_22375955 Show fit	10.60	ENSRNOT00000063915 ENSRNOT00000034784	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr7_-_12673659 Show fit	10.59	ENSRNOT00000091650 ENSRNOT00000041277 ENSRNOT00000044865	Ptbp1 NCBI RGD Ensembl Show fit	polypyrimidine tract binding protein 1
chr3_-_23066658 Show fit	10.58	ENSRNOT00000018751	Nr6a1 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 6, group A, member 1
chr5_+_124442293 Show fit	10.51	ENSRNOT00000041922	RGD1564074 NCBI RGD Ensembl Show fit	similar to novel protein
chr1_+_224800252 Show fit	10.49	ENSRNOT00000024488	Slc22a8 NCBI RGD Ensembl Show fit	solute carrier family 22 member 8
chr6_-_50846965 Show fit	10.46	ENSRNOT00000087300	Slc26a4 NCBI RGD Ensembl Show fit	solute carrier family 26 member 4
chr10_+_62981297 Show fit	10.41	ENSRNOT00000031618	Efcab5 NCBI RGD Ensembl Show fit	EF-hand calcium binding domain 5
chr2_-_198852161 Show fit	10.39	ENSRNOT00000028815	Polr3c NCBI RGD Ensembl Show fit	RNA polymerase III subunit C

Network of associatons between targets according to the STRING database.

First level regulatory network of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
20.6	61.8	GO:0006117	acetaldehyde metabolic process(GO:0006117)
15.5	46.4	GO:1902962	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
14.9	44.6	GO:0046340	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) diacylglycerol catabolic process(GO:0046340)
14.7	44.1	GO:0051037	regulation of transcription involved in meiotic cell cycle(GO:0051037)
12.2	36.7	GO:0006059	hexitol metabolic process(GO:0006059)
11.7	35.2	GO:0043323	positive regulation of natural killer cell degranulation(GO:0043323)
10.9	54.4	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
7.9	23.7	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
7.2	28.9	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
6.8	68.3	GO:0071907	determination of digestive tract left/right asymmetry(GO:0071907)
6.5	19.6	GO:0015680	intracellular copper ion transport(GO:0015680)
6.4	25.7	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
6.4	25.6	GO:0050787	detoxification of mercury ion(GO:0050787)
6.2	18.7	GO:0071422	succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
6.0	23.8	GO:1903564	regulation of protein localization to cilium(GO:1903564)
5.8	28.8	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
5.6	16.9	GO:0002397	MHC class I protein complex assembly(GO:0002397)
5.6	11.2	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
5.5	22.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
5.5	16.4	GO:0000053	argininosuccinate metabolic process(GO:0000053)
5.2	41.9	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
5.1	15.3	GO:0009216	purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) adenosine biosynthetic process(GO:0046086)
5.0	15.1	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
4.9	19.6	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
4.9	44.0	GO:0070459	prolactin secretion(GO:0070459)
4.6	13.9	GO:0060764	cell-cell signaling involved in mammary gland development(GO:0060764)
4.6	32.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
4.5	17.8	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
4.4	17.5	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
4.3	13.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
4.1	12.3	GO:0001545	primary ovarian follicle growth(GO:0001545)
4.1	16.4	GO:0018992	germ-line sex determination(GO:0018992)
4.1	16.3	GO:0046351	disaccharide biosynthetic process(GO:0046351)
4.1	20.3	GO:0015755	fructose transport(GO:0015755)
4.0	12.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
4.0	20.1	GO:0010958	regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
4.0	20.1	GO:1904640	response to methionine(GO:1904640)
4.0	11.9	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
3.9	11.7	GO:0018916	nitrobenzene metabolic process(GO:0018916)
3.9	38.8	GO:0042178	xenobiotic catabolic process(GO:0042178)
3.9	11.6	GO:0034757	negative regulation of iron ion transport(GO:0034757)
3.8	11.5	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
3.8	11.4	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
3.7	11.0	GO:0061215	mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
3.5	17.7	GO:0043152	induction of bacterial agglutination(GO:0043152)
3.5	59.5	GO:0034587	piRNA metabolic process(GO:0034587)
3.5	10.5	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
3.4	20.5	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
3.4	13.5	GO:0006565	L-serine catabolic process(GO:0006565)
3.4	13.5	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
3.3	13.2	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
3.3	13.2	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
3.3	9.9	GO:0051977	lysophospholipid transport(GO:0051977)
3.2	22.1	GO:0043686	co-translational protein modification(GO:0043686)
3.1	15.6	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
3.1	37.3	GO:0007135	meiosis II(GO:0007135)
3.0	8.9	GO:0042412	taurine biosynthetic process(GO:0042412)
3.0	17.7	GO:0042414	epinephrine metabolic process(GO:0042414)
2.9	2.9	GO:0009758	carbohydrate utilization(GO:0009758)
2.9	8.6	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
2.9	5.7	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.8	8.5	GO:0035928	rRNA import into mitochondrion(GO:0035928)
2.8	11.4	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
2.8	11.2	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
2.8	8.4	GO:0071400	cellular response to oleic acid(GO:0071400)
2.8	11.2	GO:0006069	ethanol oxidation(GO:0006069)
2.8	22.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
2.8	13.9	GO:0080154	regulation of fertilization(GO:0080154)
2.8	13.8	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
2.8	8.3	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
2.6	7.8	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
2.6	18.1	GO:0098535	de novo centriole assembly(GO:0098535)
2.6	10.3	GO:0015879	carnitine transport(GO:0015879)
2.5	15.2	GO:0006681	galactosylceramide metabolic process(GO:0006681)
2.5	7.6	GO:0090487	toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
2.5	12.6	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
2.5	34.8	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
2.5	12.4	GO:1904970	brush border assembly(GO:1904970)
2.5	7.4	GO:0072053	renal inner medulla development(GO:0072053)
2.5	7.4	GO:0071282	cellular response to iron(II) ion(GO:0071282)
2.5	12.3	GO:1901857	positive regulation of cellular respiration(GO:1901857)
2.5	12.3	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
2.4	4.9	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
2.4	9.7	GO:2000813	negative regulation of barbed-end actin filament capping(GO:2000813)
2.4	33.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
2.4	4.8	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
2.4	7.2	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
2.4	7.1	GO:0021570	rhombomere 4 development(GO:0021570)
2.4	16.5	GO:0051231	mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
2.4	21.2	GO:0052697	xenobiotic glucuronidation(GO:0052697)
2.3	18.7	GO:0015705	iodide transport(GO:0015705)
2.3	7.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
2.3	76.2	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
2.3	25.1	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
2.3	4.6	GO:0071288	cellular response to mercury ion(GO:0071288)
2.3	15.9	GO:0015808	L-alanine transport(GO:0015808)
2.3	9.0	GO:1904158	axonemal central apparatus assembly(GO:1904158)
2.2	6.7	GO:0032218	riboflavin transport(GO:0032218)
2.2	24.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
2.2	6.7	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
2.2	6.6	GO:0006214	thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
2.2	17.5	GO:0051182	coenzyme transport(GO:0051182)
2.1	44.0	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
2.1	6.3	GO:1904444	regulation of establishment of Sertoli cell barrier(GO:1904444)
2.1	6.2	GO:0034445	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
2.1	8.3	GO:0016098	monoterpenoid metabolic process(GO:0016098)
2.1	10.3	GO:1902224	ketone body metabolic process(GO:1902224)
2.1	8.3	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
2.0	20.4	GO:0036158	outer dynein arm assembly(GO:0036158)
2.0	10.1	GO:0061113	pancreas morphogenesis(GO:0061113)
2.0	8.0	GO:0060294	cilium movement involved in cell motility(GO:0060294)
2.0	5.9	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
2.0	4.0	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
2.0	15.8	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
2.0	9.8	GO:0006548	histidine catabolic process(GO:0006548)
1.9	9.7	GO:0015889	cobalamin transport(GO:0015889)
1.9	19.4	GO:0015886	heme transport(GO:0015886)
1.9	3.8	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
1.9	13.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
1.8	32.6	GO:0001675	acrosome assembly(GO:0001675)
1.8	23.2	GO:0098880	maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
1.8	16.0	GO:0006689	ganglioside catabolic process(GO:0006689)
1.8	1.8	GO:0030505	inorganic diphosphate transport(GO:0030505)
1.8	5.3	GO:0021997	neural plate axis specification(GO:0021997)
1.7	5.2	GO:0071529	cementum mineralization(GO:0071529)
1.7	12.1	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.7	8.6	GO:0009804	coumarin metabolic process(GO:0009804)
1.7	32.5	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.7	3.4	GO:0006788	heme oxidation(GO:0006788)
1.7	5.1	GO:0006562	proline catabolic process(GO:0006562)
1.7	6.8	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
1.7	8.4	GO:0001552	ovarian follicle atresia(GO:0001552)
1.7	3.3	GO:0034756	regulation of iron ion transport(GO:0034756)
1.7	3.3	GO:0060460	left lung morphogenesis(GO:0060460)
1.7	23.3	GO:0045056	transcytosis(GO:0045056)
1.6	3.3	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.6	4.9	GO:0006710	androgen catabolic process(GO:0006710)
1.6	18.0	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.6	4.9	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
1.6	4.9	GO:2000611	basement membrane disassembly(GO:0034769) positive regulation of thyroid hormone generation(GO:2000611)
1.6	30.9	GO:0051450	myoblast proliferation(GO:0051450)
1.6	4.9	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
1.6	4.8	GO:0014739	positive regulation of muscle hyperplasia(GO:0014739)
1.6	28.8	GO:0035404	histone-serine phosphorylation(GO:0035404)
1.6	6.4	GO:0030576	Cajal body organization(GO:0030576)
1.6	6.3	GO:0060155	platelet dense granule organization(GO:0060155)
1.6	20.5	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
1.6	3.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
1.6	10.9	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
1.6	3.1	GO:0043132	NAD transport(GO:0043132)
1.5	9.3	GO:0045329	carnitine biosynthetic process(GO:0045329)
1.5	12.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
1.5	10.7	GO:0031584	activation of phospholipase D activity(GO:0031584)
1.5	13.7	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
1.5	10.7	GO:0007290	spermatid nucleus elongation(GO:0007290)
1.5	18.3	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
1.5	6.0	GO:0061084	negative regulation of protein refolding(GO:0061084)
1.5	6.0	GO:0018963	phthalate metabolic process(GO:0018963)
1.5	4.4	GO:1902211	regulation of prolactin signaling pathway(GO:1902211)
1.5	10.2	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
1.4	4.3	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
1.4	12.8	GO:0007097	nuclear migration(GO:0007097)
1.4	107.5	GO:0030317	sperm motility(GO:0030317)
1.4	8.2	GO:0009071	serine family amino acid catabolic process(GO:0009071)
1.4	2.7	GO:0072061	inner medullary collecting duct development(GO:0072061)
1.4	5.4	GO:2000195	negative regulation of female gonad development(GO:2000195)
1.3	13.3	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
1.3	2.7	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
1.3	3.9	GO:0071279	cellular response to cobalt ion(GO:0071279)
1.3	3.9	GO:1990743	protein sialylation(GO:1990743)
1.3	6.4	GO:0006564	L-serine biosynthetic process(GO:0006564)
1.3	5.1	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.3	9.0	GO:0014886	transition between slow and fast fiber(GO:0014886)
1.3	5.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
1.3	6.4	GO:0050925	negative regulation of negative chemotaxis(GO:0050925)
1.3	7.6	GO:0045901	positive regulation of translational elongation(GO:0045901)
1.3	53.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
1.3	5.1	GO:1990962	carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
1.2	2.5	GO:0072179	kidney rudiment formation(GO:0072003) nephric duct formation(GO:0072179)
1.2	3.7	GO:0060166	olfactory pit development(GO:0060166)
1.2	3.7	GO:0010034	response to acetate(GO:0010034)
1.2	4.9	GO:0019344	cysteine biosynthetic process(GO:0019344)
1.2	3.6	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
1.2	7.1	GO:0050917	sensory perception of umami taste(GO:0050917)
1.2	3.5	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822)
1.2	3.5	GO:0042732	D-xylose metabolic process(GO:0042732)
1.1	2.3	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
1.1	6.8	GO:0032439	endosome localization(GO:0032439)
1.1	3.4	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
1.1	2.3	GO:0021563	glossopharyngeal nerve development(GO:0021563)
1.1	3.4	GO:0052314	isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
1.1	3.4	GO:0032474	otolith morphogenesis(GO:0032474)
1.1	4.5	GO:0036233	glycine import(GO:0036233)
1.1	13.2	GO:0042730	fibrinolysis(GO:0042730)
1.1	3.3	GO:0006742	NADP catabolic process(GO:0006742)
1.1	15.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
1.1	8.6	GO:0009446	putrescine biosynthetic process(GO:0009446)
1.1	16.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.1	13.8	GO:0043252	sodium-independent organic anion transport(GO:0043252)
1.1	4.2	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.0	8.4	GO:0003351	epithelial cilium movement(GO:0003351)
1.0	21.0	GO:0019373	epoxygenase P450 pathway(GO:0019373)
1.0	26.0	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
1.0	15.6	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.0	9.2	GO:0007343	egg activation(GO:0007343)
1.0	3.1	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
1.0	20.3	GO:0060046	regulation of acrosome reaction(GO:0060046)
1.0	3.0	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
1.0	3.0	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.0	4.9	GO:1903352	mitochondrial ornithine transport(GO:0000066) L-ornithine transmembrane transport(GO:1903352)
1.0	2.0	GO:0044108	cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
1.0	22.5	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
1.0	2.9	GO:0015811	L-cystine transport(GO:0015811)
1.0	1.9	GO:1990164	histone H2A phosphorylation(GO:1990164)
1.0	6.8	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
1.0	7.6	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
1.0	3.8	GO:0035106	operant conditioning(GO:0035106)
0.9	3.7	GO:0098705	copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.9	0.9	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.9	3.6	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
0.9	103.5	GO:0007286	spermatid development(GO:0007286)
0.9	3.6	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.9	2.7	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.9	2.7	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.9	8.1	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.9	3.5	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.9	0.9	GO:0006649	phospholipid transfer to membrane(GO:0006649)
0.9	7.9	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.9	8.8	GO:0071468	cellular response to acidic pH(GO:0071468)
0.9	2.6	GO:0006552	leucine catabolic process(GO:0006552)
0.9	5.2	GO:0060406	positive regulation of penile erection(GO:0060406)
0.9	6.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.9	9.5	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.9	17.3	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.9	2.6	GO:2000338	regulation of macrophage inflammatory protein 1 alpha production(GO:0071640) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.9	6.0	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.9	3.4	GO:0048252	lauric acid metabolic process(GO:0048252)
0.9	2.6	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.9	2.6	GO:0018094	protein polyglycylation(GO:0018094)
0.9	3.4	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.9	2.6	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698) positive regulation of actin filament-based movement(GO:1903116) negative regulation of forebrain neuron differentiation(GO:2000978)
0.8	47.8	GO:0007129	synapsis(GO:0007129)
0.8	1.7	GO:0010157	response to chlorate(GO:0010157)
0.8	2.5	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.8	4.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.8	3.3	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.8	10.7	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.8	3.3	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.8	3.3	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.8	8.9	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.8	4.9	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.8	4.0	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.8	2.4	GO:0006574	valine catabolic process(GO:0006574)
0.8	3.2	GO:0007172	signal complex assembly(GO:0007172)
0.8	11.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.8	0.8	GO:0072011	glomerular endothelium development(GO:0072011)
0.8	6.9	GO:0015870	acetylcholine transport(GO:0015870)
0.8	9.9	GO:0042407	cristae formation(GO:0042407)
0.8	16.7	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.8	4.5	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.8	21.8	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.7	1.5	GO:0048102	autophagic cell death(GO:0048102)
0.7	4.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.7	2.2	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.7	4.4	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.7	1.5	GO:0031427	response to methotrexate(GO:0031427)
0.7	5.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.7	8.0	GO:0006265	DNA topological change(GO:0006265)
0.7	6.5	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.7	7.9	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.7	2.2	GO:0060816	random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.7	1.4	GO:1900453	negative regulation of long term synaptic depression(GO:1900453)
0.7	2.2	GO:0002125	maternal aggressive behavior(GO:0002125)
0.7	12.2	GO:0036315	cellular response to sterol(GO:0036315)
0.7	2.8	GO:0006004	fucose metabolic process(GO:0006004)
0.7	9.9	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.7	6.4	GO:0006527	arginine catabolic process(GO:0006527)
0.7	4.2	GO:0070417	cellular response to cold(GO:0070417)
0.7	1.4	GO:1903334	positive regulation of protein folding(GO:1903334)
0.7	3.5	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.7	6.3	GO:0006544	glycine metabolic process(GO:0006544)
0.7	3.5	GO:0033572	transferrin transport(GO:0033572)
0.7	2.7	GO:1902534	single-organism membrane invagination(GO:1902534)
0.7	1.3	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.7	2.6	GO:0019563	glycerol catabolic process(GO:0019563)
0.6	22.7	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.6	2.6	GO:1904975	response to bleomycin(GO:1904975)
0.6	3.2	GO:0033384	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
0.6	3.1	GO:1903874	ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.6	1.9	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.6	12.1	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.6	3.6	GO:0048539	bone marrow development(GO:0048539)
0.6	2.4	GO:0006538	glutamate biosynthetic process(GO:0006537) glutamate catabolic process(GO:0006538)
0.6	1.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.6	5.9	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.6	5.3	GO:0061718	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6	2.9	GO:0061741	vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
0.6	11.1	GO:0001696	gastric acid secretion(GO:0001696)
0.6	3.5	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.6	1.2	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
0.6	1.7	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.6	2.3	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.6	3.5	GO:1902414	protein localization to cell junction(GO:1902414)
0.6	4.0	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
0.6	3.9	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6	0.6	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.5	2.7	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.5	19.9	GO:0002209	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.5	3.7	GO:0006108	malate metabolic process(GO:0006108)
0.5	2.7	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.5	3.7	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.5	12.6	GO:0016180	snRNA processing(GO:0016180)
0.5	1.0	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.5	1.0	GO:0035973	aggrephagy(GO:0035973)
0.5	2.0	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.5	4.5	GO:0060536	cartilage morphogenesis(GO:0060536)
0.5	2.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.5	1.0	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.5	9.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.5	1.5	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5	3.0	GO:2000809	positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.5	6.4	GO:0035634	response to stilbenoid(GO:0035634)
0.5	2.5	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.5	12.8	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.5	1.5	GO:0097052	L-kynurenine metabolic process(GO:0097052)
0.5	4.9	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.5	5.8	GO:0001967	suckling behavior(GO:0001967)
0.5	5.3	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.5	1.9	GO:0016240	autophagosome docking(GO:0016240)
0.5	10.5	GO:0045475	locomotor rhythm(GO:0045475)
0.5	1.9	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.5	2.4	GO:0035646	endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.5	0.9	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.5	15.7	GO:0007032	endosome organization(GO:0007032)
0.5	3.2	GO:0032933	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.5	18.3	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.5	7.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.5	1.4	GO:0016267	O-glycan processing, core 1(GO:0016267)
0.4	0.9	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.4	4.9	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.4	2.2	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.4	0.9	GO:0006566	threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.4	2.2	GO:0098885	modification of postsynaptic actin cytoskeleton(GO:0098885)
0.4	4.7	GO:0002070	epithelial cell maturation(GO:0002070)
0.4	1.7	GO:0060767	epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.4	2.1	GO:0019471	4-hydroxyproline metabolic process(GO:0019471)
0.4	1.2	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
0.4	3.7	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.4	2.0	GO:0045218	zonula adherens maintenance(GO:0045218)
0.4	5.2	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4	3.6	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.4	2.0	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.4	9.7	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4	3.1	GO:0032401	establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.4	3.5	GO:0006590	thyroid hormone generation(GO:0006590)
0.4	1.9	GO:0006591	ornithine metabolic process(GO:0006591)
0.4	7.5	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.4	1.5	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4	1.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.4	11.9	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.4	2.5	GO:0021779	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.4	3.2	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.4	4.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4	0.4	GO:0097198	histone H3-K36 trimethylation(GO:0097198)
0.4	0.7	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747) negative regulation of vitamin metabolic process(GO:0046137) cellular response to prolactin(GO:1990646)
0.4	1.8	GO:0060327	Cdc42 protein signal transduction(GO:0032488) cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.3	1.0	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.3	3.8	GO:0009635	response to herbicide(GO:0009635)
0.3	4.5	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3	2.7	GO:0061734	negative regulation of receptor recycling(GO:0001920) parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.3	1.0	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.3	1.0	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.3	0.7	GO:0030186	melatonin metabolic process(GO:0030186)
0.3	3.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3	0.6	GO:0002877	regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.3	6.7	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.3	2.2	GO:0007021	tubulin complex assembly(GO:0007021)
0.3	2.6	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3	1.6	GO:0055089	fatty acid homeostasis(GO:0055089)
0.3	0.9	GO:0071579	regulation of zinc ion transport(GO:0071579)
0.3	1.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.3	1.6	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3	0.9	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143)
0.3	4.6	GO:0032438	melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.3	1.8	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.3	0.6	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.3	1.5	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.3	2.7	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3	3.9	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3	0.6	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.3	18.8	GO:0046324	regulation of glucose import(GO:0046324)
0.3	0.9	GO:0032847	regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938)
0.3	5.0	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.3	3.5	GO:0016322	neuron remodeling(GO:0016322)
0.3	5.6	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.3	1.2	GO:0070189	kynurenine metabolic process(GO:0070189)
0.3	9.3	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.3	0.6	GO:0044313	protein K6-linked deubiquitination(GO:0044313)
0.3	1.2	GO:1903298	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.3	1.4	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.3	7.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.3	4.3	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.3	3.1	GO:0034389	lipid particle organization(GO:0034389)
0.3	7.9	GO:0006749	glutathione metabolic process(GO:0006749)
0.3	1.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.3	1.9	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.3	0.5	GO:0043397	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.3	13.5	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.3	1.3	GO:0051661	maintenance of centrosome location(GO:0051661)
0.3	4.7	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.3	1.8	GO:0060157	urinary bladder development(GO:0060157)
0.3	0.8	GO:1900135	positive regulation of renin secretion into blood stream(GO:1900135)
0.3	0.8	GO:0002458	peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) positive regulation of immature T cell proliferation in thymus(GO:0033092) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.3	1.8	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133) pyrimidine nucleoside catabolic process(GO:0046135)
0.3	0.5	GO:0060174	limb bud formation(GO:0060174)
0.3	3.9	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.3	4.4	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.3	1.0	GO:0090230	regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.2	6.2	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.2	3.4	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.2	1.0	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2	1.0	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.2	0.5	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.2	3.3	GO:0032098	regulation of appetite(GO:0032098)
0.2	1.2	GO:0061709	reticulophagy(GO:0061709)
0.2	1.2	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.2	0.9	GO:2000814	positive regulation of barbed-end actin filament capping(GO:2000814)
0.2	0.9	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934)
0.2	0.7	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2	1.8	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.2	1.8	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.2	1.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2	19.5	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2	2.5	GO:0000338	protein deneddylation(GO:0000338)
0.2	9.7	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.2	1.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2	1.8	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.2	2.7	GO:0044458	motile cilium assembly(GO:0044458)
0.2	2.2	GO:0060065	uterus development(GO:0060065)
0.2	2.2	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.2	1.8	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2	0.9	GO:0060005	vestibular reflex(GO:0060005)
0.2	2.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.2	2.8	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2	0.9	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.2	2.3	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2	10.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2	0.6	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.2	1.7	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	0.6	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.2	0.4	GO:0015793	glycerol transport(GO:0015793)
0.2	2.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.2	1.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2	2.4	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2	0.4	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.2	1.2	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.2	1.8	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.2	10.4	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.2	0.8	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.2	4.5	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2	1.9	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2	2.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.2	0.6	GO:0035425	autocrine signaling(GO:0035425)
0.2	1.4	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.2	2.9	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2	16.5	GO:0048706	embryonic skeletal system development(GO:0048706)
0.2	0.6	GO:0072014	proximal tubule development(GO:0072014)
0.2	3.4	GO:0001964	startle response(GO:0001964)
0.2	2.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.2	1.5	GO:0040016	embryonic cleavage(GO:0040016)
0.2	1.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.2	0.9	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2	5.5	GO:0016126	sterol biosynthetic process(GO:0016126)
0.2	0.5	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2	6.3	GO:0031016	pancreas development(GO:0031016)
0.2	0.5	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.2	0.5	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.2	1.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2	0.3	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.2	47.8	GO:0007283	spermatogenesis(GO:0007283)
0.2	1.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	1.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.2	0.7	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.2	0.5	GO:0022417	protein maturation by protein folding(GO:0022417)
0.2	1.0	GO:0015677	copper ion import(GO:0015677)
0.2	0.5	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.2	0.9	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2	0.5	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.2	0.5	GO:0036367	adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2	0.6	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2	0.5	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.2	1.2	GO:0008206	bile acid metabolic process(GO:0008206)
0.2	0.3	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	1.4	GO:0090662	ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1	2.5	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.1	1.3	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.4	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1	0.6	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.1	0.4	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.1	1.1	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.1	1.2	GO:0031643	positive regulation of myelination(GO:0031643)
0.1	4.3	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.1	0.9	GO:0021670	lateral ventricle development(GO:0021670)
0.1	1.8	GO:0031424	keratinization(GO:0031424)
0.1	1.1	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1	0.9	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.1	2.4	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	1.9	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	1.1	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1	3.7	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	5.4	GO:0032543	mitochondrial translation(GO:0032543)
0.1	0.4	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1	0.8	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.1	0.9	GO:0021591	ventricular system development(GO:0021591)
0.1	3.4	GO:0006953	acute-phase response(GO:0006953)
0.1	3.7	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1	0.6	GO:0006817	phosphate ion transport(GO:0006817)
0.1	0.6	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.1	1.5	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.1	1.3	GO:0043486	histone exchange(GO:0043486)
0.1	3.6	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1	0.2	GO:0045297	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.1	6.4	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1	1.3	GO:0034776	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.1	0.6	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.7	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1	0.5	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	2.4	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.1	1.7	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1	0.6	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1	0.1	GO:0015920	lipopolysaccharide transport(GO:0015920)
0.1	0.6	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1	1.2	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1	1.1	GO:0090344	negative regulation of cell aging(GO:0090344)
0.1	0.2	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.1	1.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	2.3	GO:0045116	protein neddylation(GO:0045116)
0.1	1.0	GO:0001502	cartilage condensation(GO:0001502)
0.1	2.5	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
0.1	0.3	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.1	0.7	GO:0030539	male genitalia development(GO:0030539)
0.1	1.0	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.1	1.4	GO:0070166	enamel mineralization(GO:0070166)
0.1	3.4	GO:1902652	secondary alcohol metabolic process(GO:1902652)
0.1	0.7	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1	4.7	GO:0007224	smoothened signaling pathway(GO:0007224)
0.1	0.5	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.1	0.3	GO:0072525	nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363) pyridine-containing compound biosynthetic process(GO:0072525)
0.1	5.5	GO:0000187	activation of MAPK activity(GO:0000187)
0.1	1.9	GO:0001523	retinoid metabolic process(GO:0001523)
0.1	0.7	GO:0035878	nail development(GO:0035878)
0.1	0.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	0.2	GO:0030824	negative regulation of cGMP metabolic process(GO:0030824)
0.1	0.2	GO:0002086	diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
0.1	1.6	GO:0010824	regulation of centrosome duplication(GO:0010824)
0.1	0.3	GO:0009650	UV protection(GO:0009650)
0.1	0.4	GO:0071955	recycling endosome to Golgi transport(GO:0071955)
0.1	1.0	GO:0061512	protein localization to cilium(GO:0061512)
0.1	0.9	GO:0006013	mannose metabolic process(GO:0006013)
0.1	0.8	GO:0010669	epithelial structure maintenance(GO:0010669)
0.1	0.5	GO:0098789	mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	1.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	0.3	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.1	0.9	GO:0001709	cell fate determination(GO:0001709)
0.1	0.3	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.1	0.4	GO:0007220	Notch receptor processing(GO:0007220)
0.1	0.3	GO:2000535	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1	0.9	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.1	0.5	GO:0072530	purine-containing compound transmembrane transport(GO:0072530)
0.1	0.6	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1	2.0	GO:2001222	regulation of neuron migration(GO:2001222)
0.1	0.4	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1	0.9	GO:0048854	brain morphogenesis(GO:0048854)
0.1	0.3	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.8	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1	0.2	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1	0.6	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.4	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.5	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0	0.1	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.6	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0	56.5	GO:0007608	sensory perception of smell(GO:0007608)
0.0	1.5	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	1.0	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	1.4	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.5	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.3	GO:2000737	negative regulation of stem cell differentiation(GO:2000737)
0.0	1.0	GO:0060042	retina morphogenesis in camera-type eye(GO:0060042)
0.0	0.3	GO:0007614	short-term memory(GO:0007614)
0.0	0.4	GO:0051590	positive regulation of neurotransmitter secretion(GO:0001956) positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.8	GO:0001935	endothelial cell proliferation(GO:0001935)
0.0	0.3	GO:0061045	negative regulation of wound healing(GO:0061045)
0.0	0.4	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.1	GO:0034238	macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0	0.1	GO:0060051	negative regulation of protein glycosylation(GO:0060051)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0010624	regulation of Schwann cell proliferation(GO:0010624)
0.0	0.1	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.4	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.0	0.3	GO:0046039	GTP metabolic process(GO:0046039)
0.0	0.2	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0032919	spermine acetylation(GO:0032919)
0.0	0.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.0	GO:2000687	signal transduction by trans-phosphorylation(GO:0023016) negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0	0.4	GO:0008202	steroid metabolic process(GO:0008202)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.8	35.2	GO:0061474	phagolysosome membrane(GO:0061474)
6.5	26.1	GO:0030906	retromer, cargo-selective complex(GO:0030906)
6.4	31.8	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
6.2	18.5	GO:0000802	transverse filament(GO:0000802)
5.7	45.4	GO:0097418	neurofibrillary tangle(GO:0097418)
5.6	50.8	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
5.5	38.5	GO:0005579	membrane attack complex(GO:0005579)
5.4	48.2	GO:0000439	core TFIIH complex(GO:0000439)
5.2	26.1	GO:0070695	FHF complex(GO:0070695)
4.5	54.6	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
4.2	16.9	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
4.0	11.9	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
3.2	25.6	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
3.0	26.6	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
2.9	8.6	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
2.8	33.6	GO:0001673	male germ cell nucleus(GO:0001673)
2.8	8.3	GO:0070421	DNA ligase III-XRCC1 complex(GO:0070421)
2.5	17.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
2.5	32.4	GO:0046581	intercellular canaliculus(GO:0046581)
2.5	17.4	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.4	48.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
2.2	6.5	GO:0031309	intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)
2.2	12.9	GO:0032280	symmetric synapse(GO:0032280)
2.0	20.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
2.0	7.9	GO:0034774	secretory granule lumen(GO:0034774)
1.9	13.6	GO:0071203	WASH complex(GO:0071203)
1.9	7.4	GO:0031021	interphase microtubule organizing center(GO:0031021)
1.8	5.5	GO:1990037	Lewy body core(GO:1990037)
1.8	14.6	GO:0005577	fibrinogen complex(GO:0005577)
1.8	16.2	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.8	25.0	GO:0072687	meiotic spindle(GO:0072687)
1.8	14.3	GO:0005869	dynactin complex(GO:0005869)
1.7	30.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
1.7	76.4	GO:0000795	synaptonemal complex(GO:0000795)
1.6	11.2	GO:0030991	intraciliary transport particle A(GO:0030991)
1.6	8.0	GO:1990716	axonemal central apparatus(GO:1990716)
1.5	13.6	GO:0000138	Golgi trans cisterna(GO:0000138)
1.4	5.7	GO:0008091	spectrin(GO:0008091)
1.4	74.2	GO:0005844	polysome(GO:0005844)
1.4	9.9	GO:0061617	MICOS complex(GO:0061617)
1.4	8.4	GO:1990246	uniplex complex(GO:1990246)
1.4	9.6	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
1.4	23.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
1.3	13.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
1.3	20.1	GO:0033391	chromatoid body(GO:0033391)
1.2	12.5	GO:0045179	apical cortex(GO:0045179)
1.2	17.3	GO:0070852	cell body fiber(GO:0070852)
1.2	102.8	GO:0031526	brush border membrane(GO:0031526)
1.2	19.2	GO:0001520	outer dense fiber(GO:0001520)
1.2	8.3	GO:0045293	mRNA editing complex(GO:0045293)
1.2	24.4	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
1.1	17.2	GO:1990023	mitotic spindle midzone(GO:1990023)
1.1	21.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.1	4.5	GO:0002947	tumor necrosis factor receptor superfamily complex(GO:0002947)
1.1	22.4	GO:0005640	nuclear outer membrane(GO:0005640)
1.1	23.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
1.1	3.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
1.0	26.0	GO:0002080	acrosomal membrane(GO:0002080)
1.0	2.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.9	5.5	GO:0036128	CatSper complex(GO:0036128)
0.9	2.7	GO:0042627	chylomicron(GO:0042627)
0.9	3.7	GO:0097524	sperm plasma membrane(GO:0097524)
0.9	4.5	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.9	95.2	GO:0001669	acrosomal vesicle(GO:0001669)
0.9	7.0	GO:1990909	Wnt signalosome(GO:1990909)
0.9	4.3	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.9	1.7	GO:0071439	clathrin complex(GO:0071439)
0.9	7.8	GO:0071141	SMAD protein complex(GO:0071141)
0.9	6.0	GO:0002177	manchette(GO:0002177)
0.9	2.6	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.8	9.2	GO:0043202	lysosomal lumen(GO:0043202)
0.8	15.5	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.8	4.0	GO:1903768	sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.8	99.6	GO:0031514	motile cilium(GO:0031514)
0.8	2.4	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.8	48.9	GO:0044439	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.7	3.7	GO:0043203	axon hillock(GO:0043203)
0.7	50.4	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.7	2.2	GO:0008537	proteasome activator complex(GO:0008537)
0.7	4.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.7	13.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.7	2.7	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.7	15.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.7	2.6	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.6	10.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.6	3.2	GO:0070195	growth hormone receptor complex(GO:0070195)
0.6	9.4	GO:0036038	MKS complex(GO:0036038)
0.6	4.9	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.6	10.0	GO:0032039	integrator complex(GO:0032039)
0.6	3.5	GO:0030896	checkpoint clamp complex(GO:0030896)
0.6	3.3	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.5	1.6	GO:0043511	inhibin complex(GO:0043511)
0.5	2.6	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5	5.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.5	3.1	GO:0090543	Flemming body(GO:0090543)
0.5	13.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.5	1.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.5	1.9	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.5	7.4	GO:0010369	chromocenter(GO:0010369)
0.5	145.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.4	1.8	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4	0.9	GO:0031310	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.4	51.9	GO:0005923	bicellular tight junction(GO:0005923)
0.4	25.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.4	4.5	GO:0044294	dendritic growth cone(GO:0044294)
0.4	5.6	GO:0030061	mitochondrial crista(GO:0030061)
0.4	47.2	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.4	2.0	GO:0001674	female germ cell nucleus(GO:0001674)
0.4	3.5	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.4	22.1	GO:0034707	chloride channel complex(GO:0034707)
0.4	2.7	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4	28.1	GO:0045095	keratin filament(GO:0045095)
0.4	0.8	GO:0061689	tricellular tight junction(GO:0061689)
0.4	6.0	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4	5.8	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.4	34.5	GO:0072562	blood microparticle(GO:0072562)
0.4	4.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.4	8.9	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.3	2.0	GO:0036449	microtubule minus-end(GO:0036449)
0.3	0.9	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.3	1.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.3	7.6	GO:0097440	apical dendrite(GO:0097440)
0.3	2.0	GO:0005796	Golgi lumen(GO:0005796)
0.3	1.4	GO:0043293	apoptosome(GO:0043293)
0.3	2.8	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3	1.4	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3	1.1	GO:0032044	DSIF complex(GO:0032044)
0.3	0.8	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.2	41.1	GO:0036464	cytoplasmic ribonucleoprotein granule(GO:0036464)
0.2	11.9	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.2	6.7	GO:0030286	dynein complex(GO:0030286)
0.2	3.1	GO:0032433	filopodium tip(GO:0032433)
0.2	4.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	0.7	GO:0044299	C-fiber(GO:0044299)
0.2	0.9	GO:0048788	cytoskeleton of presynaptic active zone(GO:0048788)
0.2	2.1	GO:0035253	ciliary rootlet(GO:0035253)
0.2	1.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.2	1.0	GO:0045098	type III intermediate filament(GO:0045098)
0.2	1.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	0.6	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.2	0.9	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	3.9	GO:0046930	pore complex(GO:0046930)
0.2	9.6	GO:0030667	secretory granule membrane(GO:0030667)
0.2	9.4	GO:0005882	intermediate filament(GO:0005882)
0.2	1.2	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.2	0.9	GO:0001740	Barr body(GO:0001740)
0.2	1.5	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2	1.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.2	5.9	GO:0005637	nuclear inner membrane(GO:0005637)
0.2	13.7	GO:0000786	nucleosome(GO:0000786)
0.2	4.6	GO:0030673	axolemma(GO:0030673)
0.2	1.1	GO:0070449	elongin complex(GO:0070449)
0.2	1.7	GO:0005916	fascia adherens(GO:0005916)
0.1	0.6	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1	4.2	GO:0005921	gap junction(GO:0005921)
0.1	4.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	1.4	GO:0070652	HAUS complex(GO:0070652)
0.1	0.9	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.1	2.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	0.8	GO:0031983	vesicle lumen(GO:0031983)
0.1	5.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	5.3	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	0.9	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	34.7	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.1	1.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	8.5	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	4.1	GO:0032420	stereocilium(GO:0032420)
0.1	1.4	GO:0097449	astrocyte projection(GO:0097449)
0.1	11.1	GO:0000922	spindle pole(GO:0000922)
0.1	1.6	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	5.4	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.4	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	0.7	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.1	2.9	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	0.4	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	0.5	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	0.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	1.0	GO:0017119	Golgi transport complex(GO:0017119)
0.1	3.5	GO:0016592	mediator complex(GO:0016592)
0.1	0.4	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	0.7	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	1.3	GO:0060170	ciliary membrane(GO:0060170)
0.1	2.0	GO:0030120	vesicle coat(GO:0030120)
0.1	0.9	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.1	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	0.3	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	0.7	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	2.9	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	0.2	GO:0044327	dendritic spine head(GO:0044327)
0.1	29.5	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.1	1.0	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0042827	platelet dense granule(GO:0042827)
0.0	1.0	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.1	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0043296	apical junction complex(GO:0043296)
0.0	0.1	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.9	44.6	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
12.4	49.5	GO:0004027	alcohol sulfotransferase activity(GO:0004027)
12.2	73.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
10.6	31.8	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
6.8	34.2	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
6.2	18.7	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
5.8	28.8	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
5.7	17.2	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
5.4	21.7	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
5.4	10.8	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
5.3	16.0	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
5.2	46.5	GO:0032050	clathrin heavy chain binding(GO:0032050)
5.1	35.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
4.7	28.0	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
4.6	18.6	GO:0061665	SUMO ligase activity(GO:0061665)
4.5	13.5	GO:0004736	pyruvate carboxylase activity(GO:0004736)
4.0	20.2	GO:0043682	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
4.0	51.8	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
3.8	11.5	GO:0004370	glycerol kinase activity(GO:0004370)
3.8	45.9	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
3.7	18.6	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
3.6	10.8	GO:0005302	L-tyrosine transmembrane transporter activity(GO:0005302)
3.6	10.7	GO:0031752	D5 dopamine receptor binding(GO:0031752)
3.5	10.6	GO:0001069	regulatory region RNA binding(GO:0001069)
3.5	31.6	GO:0008494	translation activator activity(GO:0008494)
3.3	26.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
3.3	13.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
3.2	9.7	GO:0008948	oxaloacetate decarboxylase activity(GO:0008948)
3.2	9.6	GO:0004769	steroid delta-isomerase activity(GO:0004769)
3.1	12.3	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
2.9	61.8	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
2.9	8.6	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
2.8	11.3	GO:0008158	hedgehog receptor activity(GO:0008158)
2.8	13.8	GO:0051185	coenzyme transporter activity(GO:0051185)
2.7	13.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
2.7	34.8	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
2.7	8.0	GO:0031871	proteinase activated receptor binding(GO:0031871)
2.6	13.1	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
2.6	10.5	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
2.6	15.6	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
2.6	25.8	GO:0051959	dynein light intermediate chain binding(GO:0051959)
2.6	7.7	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
2.5	22.7	GO:0046790	virion binding(GO:0046790)
2.5	22.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
2.5	9.9	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
2.5	7.4	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
2.4	12.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
2.4	9.5	GO:0030984	kininogen binding(GO:0030984)
2.4	42.5	GO:0043295	glutathione binding(GO:0043295)
2.3	9.1	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
2.2	6.7	GO:0032217	riboflavin transporter activity(GO:0032217)
2.2	44.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
2.2	6.6	GO:0017113	dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
2.2	6.6	GO:0008142	oxysterol binding(GO:0008142)
2.2	32.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
2.2	10.9	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
2.2	19.4	GO:0015232	heme transporter activity(GO:0015232)
2.1	4.3	GO:0031711	bradykinin receptor binding(GO:0031711)
2.1	12.7	GO:0042289	MHC class II protein binding(GO:0042289)
2.1	6.4	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
2.1	54.7	GO:0070840	dynein complex binding(GO:0070840)
2.1	6.2	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
2.1	8.2	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
2.0	24.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
2.0	16.0	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
2.0	5.9	GO:0034057	RNA strand-exchange activity(GO:0034057)
2.0	7.8	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
2.0	43.0	GO:0070577	lysine-acetylated histone binding(GO:0070577)
1.9	15.0	GO:0015645	fatty acid ligase activity(GO:0015645)
1.8	22.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
1.8	23.2	GO:0098919	structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
1.8	14.2	GO:0008430	selenium binding(GO:0008430)
1.8	7.1	GO:0016842	amidine-lyase activity(GO:0016842)
1.8	7.0	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
1.7	12.2	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.7	54.0	GO:0015020	glucuronosyltransferase activity(GO:0015020)
1.7	24.0	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.7	5.2	GO:0004046	aminoacylase activity(GO:0004046)
1.7	6.8	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
1.7	3.4	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
1.7	10.2	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
1.7	6.8	GO:0016672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
1.7	5.1	GO:0004657	proline dehydrogenase activity(GO:0004657)
1.7	8.4	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
1.6	6.6	GO:0033149	FFAT motif binding(GO:0033149)
1.6	8.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
1.6	11.3	GO:0004065	arylsulfatase activity(GO:0004065)
1.6	12.4	GO:0070008	serine-type exopeptidase activity(GO:0070008)
1.5	12.2	GO:0045505	dynein intermediate chain binding(GO:0045505)
1.5	12.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.5	20.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
1.5	13.4	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
1.5	7.4	GO:0016936	galactoside binding(GO:0016936)
1.5	4.4	GO:0070573	metallodipeptidase activity(GO:0070573)
1.5	8.7	GO:0046624	sphingolipid transporter activity(GO:0046624)
1.5	21.8	GO:0004745	retinol dehydrogenase activity(GO:0004745)
1.5	47.9	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
1.4	5.5	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
1.4	4.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
1.4	4.1	GO:1902379	chemoattractant activity involved in axon guidance(GO:1902379)
1.3	8.0	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
1.3	23.0	GO:0050308	sugar-phosphatase activity(GO:0050308)
1.3	22.9	GO:0071949	FAD binding(GO:0071949)
1.3	3.8	GO:0004655	porphobilinogen synthase activity(GO:0004655)
1.3	25.1	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
1.2	2.4	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
1.2	3.6	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.2	20.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
1.2	5.9	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.2	24.7	GO:0019200	carbohydrate kinase activity(GO:0019200)
1.2	3.5	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.1	47.0	GO:0070330	aromatase activity(GO:0070330)
1.1	3.4	GO:0004058	aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
1.1	4.4	GO:0034431	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.1	13.8	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.1	7.4	GO:0031433	telethonin binding(GO:0031433)
1.0	10.4	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
1.0	6.2	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
1.0	4.0	GO:0031686	A1 adenosine receptor binding(GO:0031686)
1.0	5.0	GO:0015166	polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
1.0	5.9	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
1.0	10.8	GO:0070410	co-SMAD binding(GO:0070410)
1.0	2.9	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
1.0	11.7	GO:0004000	adenosine deaminase activity(GO:0004000)
1.0	3.9	GO:0010465	nerve growth factor receptor activity(GO:0010465)
1.0	3.8	GO:0004594	pantothenate kinase activity(GO:0004594)
0.9	25.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.9	3.7	GO:0034584	piRNA binding(GO:0034584)
0.9	6.4	GO:0045503	dynein light chain binding(GO:0045503)
0.9	3.5	GO:0070699	type II activin receptor binding(GO:0070699)
0.9	2.6	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.9	9.6	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.9	2.6	GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.9	4.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.9	2.6	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.9	32.4	GO:0045182	translation regulator activity(GO:0045182)
0.9	4.3	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.8	17.6	GO:0034185	apolipoprotein binding(GO:0034185)
0.8	3.3	GO:0016160	amylase activity(GO:0016160)
0.8	5.0	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.8	3.2	GO:0004903	growth hormone receptor activity(GO:0004903)
0.8	3.2	GO:0043532	angiostatin binding(GO:0043532)
0.8	3.2	GO:0070697	activin receptor binding(GO:0070697)
0.8	7.9	GO:0070878	primary miRNA binding(GO:0070878)
0.8	11.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.8	11.7	GO:0001056	RNA polymerase III activity(GO:0001056)
0.8	2.3	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.8	12.4	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.8	2.3	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.8	0.8	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.8	7.6	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.7	5.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.7	6.0	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.7	2.2	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.7	3.6	GO:1990254	keratin filament binding(GO:1990254)
0.7	4.3	GO:0070061	fructose binding(GO:0070061)
0.7	1.4	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.7	4.9	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.7	5.6	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.7	2.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.7	13.9	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.7	5.3	GO:0031419	cobalamin binding(GO:0031419)
0.7	5.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6	3.9	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.6	2.6	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.6	3.2	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.6	4.4	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.6	3.8	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.6	3.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.6	1.9	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.6	4.9	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.6	10.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.6	3.1	GO:0030348	syntaxin-3 binding(GO:0030348)
0.6	6.8	GO:0045499	chemorepellent activity(GO:0045499)
0.6	3.7	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.6	4.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.6	1.8	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.6	1.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6	5.2	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.6	6.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.6	2.9	GO:0005550	pheromone binding(GO:0005550)
0.6	20.0	GO:0016831	carboxy-lyase activity(GO:0016831)
0.6	15.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.6	12.8	GO:0071837	HMG box domain binding(GO:0071837)
0.5	2.7	GO:0001155	TFIIIA-class transcription factor binding(GO:0001155)
0.5	28.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5	2.7	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5	2.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.5	2.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.5	4.3	GO:0032184	SUMO polymer binding(GO:0032184)
0.5	1.1	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5	2.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.5	8.9	GO:0050811	GABA receptor binding(GO:0050811)
0.5	2.6	GO:0097322	7SK snRNA binding(GO:0097322)
0.5	2.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.5	31.5	GO:0051287	NAD binding(GO:0051287)
0.5	1.5	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.5	3.4	GO:0061133	endopeptidase activator activity(GO:0061133)
0.5	7.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.5	7.2	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.5	6.7	GO:0051787	misfolded protein binding(GO:0051787)
0.5	3.3	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.5	1.9	GO:0005534	galactose binding(GO:0005534)
0.5	1.4	GO:0047635	L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.5	33.0	GO:0003724	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.5	0.9	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.5	9.8	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.5	53.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.5	2.3	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.5	1.4	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.4	0.9	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.4	2.7	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.4	4.4	GO:0010181	FMN binding(GO:0010181)
0.4	0.8	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.4	6.6	GO:0008483	transaminase activity(GO:0008483)
0.4	1.6	GO:1904288	BAT3 complex binding(GO:1904288)
0.4	2.5	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.4	7.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.4	1.2	GO:0004775	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.4	1.2	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.4	1.6	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4	2.4	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.4	3.9	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.4	0.4	GO:0033041	sweet taste receptor activity(GO:0033041)
0.4	1.2	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.4	3.9	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.4	3.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.4	82.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.4	3.1	GO:0051184	cofactor transporter activity(GO:0051184)
0.4	1.2	GO:0042015	interleukin-20 binding(GO:0042015)
0.4	1.5	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4	1.5	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.4	30.1	GO:0051082	unfolded protein binding(GO:0051082)
0.3	3.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3	1.0	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3	4.7	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	1.3	GO:0004645	phosphorylase activity(GO:0004645)
0.3	2.3	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3	0.3	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	4.0	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3	1.3	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3	2.6	GO:0016421	CoA carboxylase activity(GO:0016421)
0.3	5.5	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3	6.5	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.3	10.3	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.3	1.0	GO:0089720	caspase binding(GO:0089720)
0.3	4.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.3	0.3	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.3	1.6	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.3	2.7	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.3	0.9	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.3	3.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	1.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3	0.9	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.3	4.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.3	0.9	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.3	3.2	GO:0008432	JUN kinase binding(GO:0008432)
0.3	4.6	GO:0015643	toxic substance binding(GO:0015643)
0.3	3.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3	8.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.3	2.5	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3	2.8	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.3	0.6	GO:0050682	AF-2 domain binding(GO:0050682)
0.3	2.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.3	2.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	4.6	GO:0071617	lysophospholipid acyltransferase activity(GO:0071617)
0.3	0.3	GO:0043426	MRF binding(GO:0043426)
0.3	5.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.3	25.9	GO:0043130	ubiquitin binding(GO:0043130)
0.3	1.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.3	1.8	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.3	4.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.3	1.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.3	5.9	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3	3.6	GO:0033038	bitter taste receptor activity(GO:0033038)
0.3	5.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.3	3.3	GO:0070097	delta-catenin binding(GO:0070097)
0.3	3.8	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	2.7	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.2	8.1	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	2.4	GO:0005132	type I interferon receptor binding(GO:0005132)
0.2	2.2	GO:0016668	thioredoxin-disulfide reductase activity(GO:0004791) oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.2	1.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.2	3.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.2	0.5	GO:0034618	arginine binding(GO:0034618)
0.2	1.4	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.2	1.1	GO:0043394	proteoglycan binding(GO:0043394)
0.2	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.2	0.7	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.2	0.9	GO:0004064	arylesterase activity(GO:0004064)
0.2	0.7	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
0.2	4.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248)
0.2	0.6	GO:0046592	polyamine oxidase activity(GO:0046592)
0.2	0.6	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.2	0.6	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.2	3.1	GO:0016854	racemase and epimerase activity(GO:0016854)
0.2	5.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.2	1.8	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	1.2	GO:0001515	opioid peptide activity(GO:0001515)
0.2	0.6	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2	0.8	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829)
0.2	1.0	GO:0016723	cupric reductase activity(GO:0008823) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2	0.8	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.2	2.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	1.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	6.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.2	20.0	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.2	10.2	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.2	3.0	GO:0017081	chloride channel regulator activity(GO:0017081)
0.2	12.8	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.2	9.9	GO:0051087	chaperone binding(GO:0051087)
0.2	0.6	GO:0052723	inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2	0.7	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.2	2.0	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.2	1.1	GO:0034711	inhibin binding(GO:0034711)
0.2	0.7	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.2	1.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.2	0.9	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	4.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2	1.0	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.2	1.4	GO:0016783	sulfurtransferase activity(GO:0016783)
0.2	1.0	GO:0035240	dopamine binding(GO:0035240)
0.2	2.7	GO:0008301	DNA binding, bending(GO:0008301)
0.2	2.9	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.2	0.7	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.2	13.1	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.2	22.8	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.2	1.0	GO:0004126	cytidine deaminase activity(GO:0004126)
0.2	1.1	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.2	2.7	GO:0005537	mannose binding(GO:0005537)
0.2	0.9	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.2	2.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2	0.5	GO:0001605	adrenomedullin receptor activity(GO:0001605)
0.1	1.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	8.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	1.3	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	3.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.8	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1	16.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	14.4	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
0.1	0.6	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.6	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	1.0	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.4	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.9	GO:0070628	proteasome binding(GO:0070628)
0.1	0.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	8.1	GO:0003777	microtubule motor activity(GO:0003777)
0.1	0.4	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1	1.2	GO:0048038	quinone binding(GO:0048038)
0.1	1.8	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.5	GO:0009378	four-way junction helicase activity(GO:0009378)
0.1	0.6	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.6	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1	1.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	0.6	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.7	GO:0070513	death domain binding(GO:0070513)
0.1	0.8	GO:0039706	co-receptor binding(GO:0039706)
0.1	0.4	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1	1.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	3.0	GO:0050699	WW domain binding(GO:0050699)
0.1	1.0	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	1.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	1.9	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	4.2	GO:0002039	p53 binding(GO:0002039)
0.1	2.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	2.8	GO:0015485	cholesterol binding(GO:0015485)
0.1	8.2	GO:0030165	PDZ domain binding(GO:0030165)
0.1	1.1	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.1	4.3	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	0.5	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	1.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	0.9	GO:0008171	O-methyltransferase activity(GO:0008171)
0.1	0.2	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	1.7	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.2	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.1	0.7	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	0.7	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.1	0.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	1.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	1.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	1.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	1.4	GO:0004497	monooxygenase activity(GO:0004497)
0.0	52.7	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.7	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	1.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.5	GO:0017171	serine hydrolase activity(GO:0017171)
0.0	0.0	GO:0017002	activin receptor activity, type I(GO:0016361) activin-activated receptor activity(GO:0017002)
0.0	3.5	GO:0008083	growth factor activity(GO:0008083)
0.0	0.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0019809	spermidine binding(GO:0019809)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0	0.1	GO:0071723	lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.0	0.2	GO:0010851	cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0	0.3	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.2	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.7	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	11.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.6	19.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.6	131.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5	28.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.4	0.7	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.4	7.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	4.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	0.4	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.3	7.8	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.3	1.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.3	5.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	0.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	8.9	PID AURORA A PATHWAY	Aurora A signaling
0.2	0.9	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	5.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2	2.5	PID ALK2 PATHWAY	ALK2 signaling events
0.2	1.8	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	1.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	3.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	9.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	5.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	6.2	PID PLK1 PATHWAY	PLK1 signaling events
0.1	6.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	6.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	0.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	3.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	8.9	PID P73PATHWAY	p73 transcription factor network
0.1	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	2.5	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	0.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.7	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	1.5	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.3	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.8	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.7	10.7	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
3.5	89.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
3.4	50.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
3.3	42.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
2.8	8.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
2.6	44.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
2.3	43.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
2.2	47.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
2.1	23.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
2.1	12.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.0	16.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
2.0	32.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
1.8	35.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.7	19.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.7	24.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.7	3.4	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
1.6	12.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
1.5	19.7	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
1.5	43.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
1.4	11.0	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
1.4	26.1	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.4	15.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
1.3	37.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
1.3	21.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.2	69.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
1.2	4.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
1.2	1.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
1.1	20.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.1	6.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
1.1	12.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
1.0	25.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
1.0	54.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.9	26.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.9	31.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.9	13.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.9	0.9	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.9	151.2	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.9	11.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.8	18.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.8	12.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.8	28.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.8	14.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.8	10.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.7	19.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.7	25.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.7	24.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.7	7.9	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.6	3.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.6	5.7	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.6	9.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.6	15.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.6	3.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.5	7.8	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.5	4.8	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.5	23.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.5	3.8	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.5	10.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.5	13.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.5	9.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	15.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.4	9.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.4	2.5	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.4	1.8	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.4	9.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.3	14.6	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.3	7.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	4.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.3	21.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.3	1.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.3	3.9	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.3	4.0	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.3	4.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	16.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	9.4	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.2	7.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	5.0	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.2	4.0	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.2	2.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	22.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.2	4.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	2.0	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.2	3.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.2	4.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2	2.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	1.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	3.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	4.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	1.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	10.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	1.9	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	6.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	2.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.2	2.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	1.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1	1.5	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	3.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.2	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	1.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.9	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.1	0.9	REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	Genes involved in Signaling by TGF-beta Receptor Complex
0.1	2.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	15.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	3.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	1.5	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1	0.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	3.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	1.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.6	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	0.4	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	2.1	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.1	2.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.0	0.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane

Results for Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

Z-value: 1.09

Motif logo

Transcription factors associated with Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

Activity-expression correlation:

Activity profile of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec motif

Sorted Z-values of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Arntl_Tfe3_Mlx_Mitf_Mlxipl_Tfec

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: