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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Barhl2

Z-value: 0.61

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Transcription factors associated with Barhl2

Gene Symbol Gene ID Gene Info
Barhl2
ENSRNOG00000002117 BarH-like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Barhl2rn6_v1_chr14_+_4362717_4362717-0.327.5e-09Click!

Activity profile of Barhl2 motif

Sorted Z-values of Barhl2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_88122233 26.13 ENSRNOT00000083895
ENSRNOT00000005285
Krt14
keratin 14
chr17_-_9762813 20.43 ENSRNOT00000033749
Slc34a1
solute carrier family 34 member 1
chr20_-_4070721 19.39 ENSRNOT00000000523
RT1-Ba
RT1 class II, locus Ba
chr10_+_31324512 16.07 ENSRNOT00000008559
Fndc9
fibronectin type III domain containing 9
chr7_+_141249044 15.97 ENSRNOT00000084911
Aqp5
aquaporin 5
chr3_+_117421604 14.47 ENSRNOT00000008860
ENSRNOT00000008857
Slc12a1
solute carrier family 12 member 1
chr13_+_47572219 13.41 ENSRNOT00000088449
ENSRNOT00000087664
ENSRNOT00000005853
Pigr
polymeric immunoglobulin receptor
chr5_-_159946446 13.35 ENSRNOT00000089184
Clcnka
chloride voltage-gated channel Ka
chr1_+_81230612 12.81 ENSRNOT00000026489
Kcnn4
potassium calcium-activated channel subfamily N member 4
chr17_-_43807540 12.40 ENSRNOT00000074763
LOC684762
similar to CG31613-PA
chr12_-_22138382 11.06 ENSRNOT00000001899
Lrch4
leucine rich repeats and calponin homology domain containing 4
chr5_-_159962218 10.96 ENSRNOT00000050729
Clcnkb
chloride voltage-gated channel Kb
chr6_-_92121351 10.48 ENSRNOT00000006374
Cdkl1
cyclin dependent kinase like 1
chr6_-_131914028 8.60 ENSRNOT00000007602
Bcl11b
B-cell CLL/lymphoma 11B
chr7_-_143228060 8.50 ENSRNOT00000088923
ENSRNOT00000012640
Krt75
keratin 75
chr20_-_157665 8.06 ENSRNOT00000048858
ENSRNOT00000079494
RT1-CE10
RT1 class I, locus CE10
chr1_+_193187972 7.84 ENSRNOT00000090172
ENSRNOT00000065342
Slc5a11
solute carrier family 5 member 11
chr14_-_21299068 7.72 ENSRNOT00000065778
Amtn
amelotin
chr20_+_44680449 7.28 ENSRNOT00000000728
Traf3ip2
Traf3 interacting protein 2
chr12_-_51877624 6.90 ENSRNOT00000056800
Chek2
checkpoint kinase 2
chr7_-_142062870 6.80 ENSRNOT00000026531
Slc11a2
solute carrier family 11 member 2
chr20_-_157861 6.78 ENSRNOT00000084461
RT1-CE10
RT1 class I, locus CE10
chr10_-_4910305 6.60 ENSRNOT00000033122
Rmi2
RecQ mediated genome instability 2
chr4_+_158088505 6.42 ENSRNOT00000026643
Vwf
von Willebrand factor
chr20_+_4106189 6.25 ENSRNOT00000042571
RT1-Db2
RT1 class II, locus Db2
chr1_-_175586802 6.13 ENSRNOT00000071333
AABR07005027.1

chr3_-_165700489 6.07 ENSRNOT00000017008
Zfp93
zinc finger protein 93
chr10_-_86932154 5.92 ENSRNOT00000085344
Top2a
topoisomerase (DNA) II alpha
chr2_-_112831476 5.83 ENSRNOT00000018055
Ect2
epithelial cell transforming 2
chrX_+_71335491 5.73 ENSRNOT00000076003
Nono
non-POU domain containing, octamer-binding
chr4_+_57378069 5.65 ENSRNOT00000080173
ENSRNOT00000011851
Nrf1
nuclear respiratory factor 1
chr5_-_115387377 5.53 ENSRNOT00000036030
ENSRNOT00000077492
RGD1560146
similar to hypothetical protein MGC34837
chr15_+_31178339 5.39 ENSRNOT00000089064
AABR07017798.2

chr16_-_49453394 5.28 ENSRNOT00000041617
Lrp2bp
Lrp2 binding protein
chr10_+_105393072 5.25 ENSRNOT00000013359
Ubald2
UBA-like domain containing 2
chr1_-_89539210 5.15 ENSRNOT00000077462
ENSRNOT00000028644
Hpn
hepsin
chr10_+_59799123 5.04 ENSRNOT00000026493
Trpv1
transient receptor potential cation channel, subfamily V, member 1
chr13_-_83425641 4.95 ENSRNOT00000063870
Tbx19
T-box 19
chr8_+_48665652 4.72 ENSRNOT00000059715
H2afx
H2A histone family, member X
chr15_+_29157294 4.63 ENSRNOT00000085162
AABR07017604.1

chr1_-_247821728 4.57 ENSRNOT00000021958
Ermp1
endoplasmic reticulum metallopeptidase 1
chr10_+_104523996 4.43 ENSRNOT00000065339
ENSRNOT00000086747
Itgb4
integrin subunit beta 4
chr9_+_15513063 4.16 ENSRNOT00000020499
Taf8
TATA-box binding protein associated factor 8
chr13_+_25966810 4.10 ENSRNOT00000086167
Zcchc2
zinc finger CCHC-type containing 2
chr7_+_142397371 4.10 ENSRNOT00000040890
ENSRNOT00000065379
Slc4a8
solute carrier family 4 member 8
chr7_-_142063212 3.97 ENSRNOT00000089912
Slc11a2
solute carrier family 11 member 2
chr1_+_178351680 3.93 ENSRNOT00000018532
ENSRNOT00000076925
ENSRNOT00000076430
ENSRNOT00000076756
Far1
fatty acyl CoA reductase 1
chr1_-_64090017 3.57 ENSRNOT00000086622
ENSRNOT00000091654
Rps9
ribosomal protein S9
chr12_-_24556976 3.57 ENSRNOT00000041798
Bcl7b
BCL tumor suppressor 7B
chr1_-_64021321 3.39 ENSRNOT00000090819
Rps9
ribosomal protein S9
chr10_-_15098791 3.14 ENSRNOT00000026139
Chtf18
chromosome transmission fidelity factor 18
chr9_+_92565366 3.00 ENSRNOT00000023184
Csprs
component of Sp100-rs
chr7_-_73130740 2.96 ENSRNOT00000075584
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr10_-_48038647 2.80 ENSRNOT00000078448
Prpsap2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr17_-_84830185 2.68 ENSRNOT00000040697
Skida1
SKI/DACH domain containing 1
chr17_+_17965881 2.66 ENSRNOT00000021751
Dek
DEK proto-oncogene
chr3_-_171342646 2.62 ENSRNOT00000071853
Pmepa1
prostate transmembrane protein, androgen induced 1
chr6_-_128149220 2.46 ENSRNOT00000014204
Gsc
goosecoid homeobox
chr13_+_25966428 2.45 ENSRNOT00000061814
ENSRNOT00000003870
Zcchc2
zinc finger CCHC-type containing 2
chr3_+_176821652 2.43 ENSRNOT00000055030
Rtel1
regulator of telomere elongation helicase 1
chr3_-_147487170 2.39 ENSRNOT00000077580
Fam110a
family with sequence similarity 110, member A
chrX_-_115496045 2.33 ENSRNOT00000051134
LOC100361854
ribosomal protein S26-like
chr2_+_210880777 2.32 ENSRNOT00000026237
Gnat2
G protein subunit alpha transducin 2
chr15_+_44441856 2.26 ENSRNOT00000018006
Gnrh1
gonadotropin releasing hormone 1
chr5_+_144106802 2.23 ENSRNOT00000035637
ENSRNOT00000079779
Lsm10
LSM10, U7 small nuclear RNA associated
chr6_+_3375476 2.22 ENSRNOT00000045349
LOC102551744
eukaryotic translation initiation factor 1-like
chr5_-_164679654 2.21 ENSRNOT00000035695
LOC100911456
migration and invasion-inhibitory protein-like
chr2_-_197935567 2.18 ENSRNOT00000085404
Rprd2
regulation of nuclear pre-mRNA domain containing 2
chr1_-_137359072 2.12 ENSRNOT00000014553
Klhl25
kelch-like family member 25
chr1_-_164101578 2.06 ENSRNOT00000022176
Uvrag
UV radiation resistance associated
chr10_-_12030416 2.03 ENSRNOT00000010442
Zfp263
zinc finger protein 263
chr15_-_83494423 2.02 ENSRNOT00000037588
Dis3
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
chr10_-_83655182 1.97 ENSRNOT00000007897
Abi3
ABI family, member 3
chrX_+_984798 1.96 ENSRNOT00000073016
Zfp182
zinc finger protein 182
chr11_+_82194657 1.95 ENSRNOT00000002445
Etv5
ets variant 5
chr16_+_6903212 1.93 ENSRNOT00000023314
Tmem110
transmembrane protein 110
chr4_-_66955732 1.89 ENSRNOT00000084282
Kdm7a
lysine (K)-specific demethylase 7A
chr10_-_104482838 1.88 ENSRNOT00000007246
Recql5
RecQ like helicase 5
chr14_+_43512901 1.87 ENSRNOT00000050664
Apbb2
amyloid beta precursor protein binding family B member 2
chr17_-_42031265 1.87 ENSRNOT00000068021
Dcdc2
doublecortin domain containing 2
chr17_+_78735598 1.87 ENSRNOT00000020854
Hspa14
heat shock protein family A, member 14
chr5_-_57845509 1.87 ENSRNOT00000035541
Kif24
kinesin family member 24
chr16_-_75855745 1.82 ENSRNOT00000031291
Agpat5
1-acylglycerol-3-phosphate O-acyltransferase 5
chr16_+_71787966 1.80 ENSRNOT00000080084
Htra4
HtrA serine peptidase 4
chr11_+_73930753 1.71 ENSRNOT00000087747
RGD1562415
similar to 40S ribosomal protein S26
chr20_+_27975549 1.67 ENSRNOT00000092075
Lims1
LIM zinc finger domain containing 1
chr1_-_220067123 1.61 ENSRNOT00000071020
ENSRNOT00000072373
Rbm14
RNA binding motif protein 14
chr9_+_3238077 1.60 ENSRNOT00000088083
RGD1559808
similar to 40S ribosomal protein S26
chr18_+_56364620 1.54 ENSRNOT00000068535
ENSRNOT00000086033
Pdgfrb
platelet derived growth factor receptor beta
chr13_-_111972603 1.53 ENSRNOT00000007870
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
chr9_+_81644355 1.46 ENSRNOT00000071700
Catip
ciliogenesis associated TTC17 interacting protein
chr1_-_64147251 1.41 ENSRNOT00000088502
Cnot3
CCR4-NOT transcription complex, subunit 3
chr2_+_197720259 1.33 ENSRNOT00000070919
Golph3l
golgi phosphoprotein 3-like
chr3_+_45683993 1.19 ENSRNOT00000038983
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr1_-_64162461 1.13 ENSRNOT00000091739
Prpf31
pre-mRNA processing factor 31
chr5_+_150957001 0.90 ENSRNOT00000017549
Rpa2
replication protein A2
chr20_-_23467190 0.78 ENSRNOT00000047773
RGD1566373
similar to large subunit ribosomal protein L36a
chr3_+_147422095 0.73 ENSRNOT00000006786
Angpt4
angiopoietin 4
chr6_-_36876805 0.69 ENSRNOT00000006482
Msgn1
mesogenin 1
chr20_+_4369178 0.55 ENSRNOT00000088079
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr13_-_68360664 0.55 ENSRNOT00000030971
Hmcn1
hemicentin 1
chr10_+_104483042 0.52 ENSRNOT00000007362
Sap30bp
SAP30 binding protein
chr8_-_12355091 0.49 ENSRNOT00000009318
Cep57
centrosomal protein 57
chrX_+_40460047 0.48 ENSRNOT00000010970
Phex
phosphate regulating endopeptidase homolog, X-linked
chr12_+_12859661 0.43 ENSRNOT00000001404
Usp42
ubiquitin specific peptidase 42
chrX_+_110789269 0.31 ENSRNOT00000086014
Rnf128
ring finger protein 128, E3 ubiquitin protein ligase
chr4_+_121912352 0.24 ENSRNOT00000086882
Vom1r98
vomeronasal 1 receptor 98
chr12_+_38965063 0.19 ENSRNOT00000074936
Morn3
MORN repeat containing 3
chr9_+_40817654 0.17 ENSRNOT00000037392
AABR07067339.1

chrX_-_25628272 0.10 ENSRNOT00000086414
Mid1
midline 1
chrX_+_50599060 0.08 ENSRNOT00000058420
AABR07038477.1

chr10_-_44095775 0.06 ENSRNOT00000047892
Olr1422
olfactory receptor 1422
chr1_+_64162672 0.06 ENSRNOT00000089713
Tfpt
TCF3 (E2A) fusion partner
chr6_-_115616766 0.06 ENSRNOT00000006143
ENSRNOT00000045870
Sel1l
SEL1L ERAD E3 ligase adaptor subunit
chr1_-_185143272 0.03 ENSRNOT00000027752
Nucb2
nucleobindin 2
chr1_-_148847662 0.01 ENSRNOT00000090329
LOC100911376
olfactory receptor 226-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Barhl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.4 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
4.8 14.5 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
4.5 13.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
4.4 26.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
3.6 10.8 GO:0015676 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444)
3.3 13.3 GO:0072053 renal inner medulla development(GO:0072053)
2.6 7.7 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
2.3 16.0 GO:0015670 carbon dioxide transport(GO:0015670)
1.7 7.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.7 6.9 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
1.7 5.2 GO:0034769 basement membrane disassembly(GO:0034769)
1.7 5.0 GO:0090210 detection of chemical stimulus involved in sensory perception of pain(GO:0050968) regulation of establishment of blood-brain barrier(GO:0090210)
1.4 8.6 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
1.4 11.0 GO:0030321 transepithelial chloride transport(GO:0030321)
1.2 12.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.0 19.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
1.0 5.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.9 11.1 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.8 6.4 GO:0070417 cellular response to cold(GO:0070417)
0.7 2.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.6 5.7 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.6 2.4 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.6 6.3 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.6 3.9 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.5 1.5 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.5 4.4 GO:0061450 nail development(GO:0035878) trophoblast cell migration(GO:0061450)
0.4 2.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.4 2.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.4 2.0 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.4 1.5 GO:0072275 cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 7.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.4 1.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 2.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.4 1.9 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.4 5.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 3.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 14.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 2.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.3 4.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.2 2.5 GO:0014029 neural crest formation(GO:0014029)
0.2 7.8 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2 1.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 1.1 GO:0048254 snoRNA localization(GO:0048254)
0.2 5.7 GO:0051593 response to folic acid(GO:0051593)
0.2 1.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 2.3 GO:0046549 retinal cone cell development(GO:0046549)
0.2 1.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 0.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 1.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 4.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 4.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 12.4 GO:0006334 nucleosome assembly(GO:0006334)
0.1 6.6 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.1 4.9 GO:0021983 pituitary gland development(GO:0021983)
0.1 2.3 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 1.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 2.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 4.6 GO:0001541 ovarian follicle development(GO:0001541)
0.1 1.9 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:0007379 segment specification(GO:0007379)
0.0 1.2 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 2.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 5.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 2.8 GO:0060348 bone development(GO:0060348)
0.0 0.3 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0070826 paraferritin complex(GO:0070826)
1.6 25.6 GO:0042613 MHC class II protein complex(GO:0042613)
1.5 5.9 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.5 5.8 GO:0097149 centralspindlin complex(GO:0097149)
1.1 6.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.9 14.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.8 5.7 GO:0042382 paraspeckles(GO:0042382)
0.6 2.3 GO:1990005 granular vesicle(GO:1990005)
0.6 2.8 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.5 42.0 GO:0045178 basal part of cell(GO:0045178)
0.4 24.3 GO:0034707 chloride channel complex(GO:0034707)
0.3 3.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 5.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 2.2 GO:0005683 U7 snRNP(GO:0005683)
0.3 1.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 13.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 7.7 GO:0005605 basal lamina(GO:0005605)
0.2 20.4 GO:0031526 brush border membrane(GO:0031526)
0.2 4.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 2.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 18.3 GO:0016605 PML body(GO:0016605)
0.2 12.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.1 GO:0005687 U4 snRNP(GO:0005687)
0.2 4.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 12.4 GO:0000786 nucleosome(GO:0000786)
0.1 1.9 GO:0060091 kinocilium(GO:0060091)
0.1 41.6 GO:0016324 apical plasma membrane(GO:0016324)
0.1 4.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 4.1 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 2.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 3.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.3 GO:0045095 keratin filament(GO:0045095)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 2.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 6.8 GO:0016607 nuclear speck(GO:0016607)
0.0 2.7 GO:0005840 ribosome(GO:0005840)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 26.1 GO:1990254 keratin filament binding(GO:1990254)
4.8 14.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
4.1 20.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
3.6 10.8 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) chromium ion transmembrane transporter activity(GO:0070835)
1.8 12.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.7 5.0 GO:0097603 temperature-gated ion channel activity(GO:0097603)
1.5 5.9 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.4 7.0 GO:1990932 5.8S rRNA binding(GO:1990932)
1.3 24.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.1 16.0 GO:0015250 water channel activity(GO:0015250)
1.1 13.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 4.4 GO:0038132 neuregulin binding(GO:0038132)
0.8 34.2 GO:0042605 peptide antigen binding(GO:0042605)
0.8 7.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.7 2.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.5 1.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.5 1.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 1.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 5.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.4 10.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4 6.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 2.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.3 3.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 1.1 GO:0030622 U4atac snRNA binding(GO:0030622)
0.1 4.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 2.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 19.8 GO:0042393 histone binding(GO:0042393)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 10.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 2.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 2.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 5.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 5.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 8.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 5.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 7.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 32.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 5.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 15.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 10.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 11.6 PID ATM PATHWAY ATM pathway
0.3 4.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 13.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 5.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 5.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.3 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 7.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 16.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 6.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 6.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 39.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 5.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 2.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 2.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 3.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 2.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 7.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 5.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 4.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 3.3 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 1.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction