ISMARA results: Cux1

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Cux1

Z-value: 1.76

Motif logo

Transcription factors associated with Cux1

Gene Symbol	Gene ID	Gene Info
Cux1 NCBI RGD Ensembl	ENSRNOG00000001424	cut-like homeobox 1
Cux1 NCBI RGD Ensembl	ENSRNOG00000059116	cut-like homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Cux1	rn6_v1_chr12_+_23151180_23151180	-0.75	4.6e-58	Click!

Activity profile of Cux1 motif

Sorted Z-values of Cux1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_83744238 Show fit	73.62	ENSRNOT00000028249	Cyp2a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily a, polypeptide 1
chr1_-_148119857 Show fit	73.40	ENSRNOT00000040325	LOC100361547 NCBI RGD Ensembl Show fit	Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr14_+_22375955 Show fit	64.22	ENSRNOT00000063915 ENSRNOT00000034784	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr17_+_9736786 Show fit	63.05	ENSRNOT00000081920	F12 NCBI RGD Ensembl Show fit	coagulation factor XII
chr5_-_78985990 Show fit	57.22	ENSRNOT00000009248	Ambp NCBI RGD Ensembl Show fit	alpha-1-microglobulin/bikunin precursor
chr14_+_20266891 Show fit	55.97	ENSRNOT00000004174	Gc NCBI RGD Ensembl Show fit	group specific component
chr1_+_83711251 Show fit	54.26	ENSRNOT00000028237 ENSRNOT00000092008	Cyp2a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily a, polypeptide 1
chr2_+_23289374 Show fit	53.46	ENSRNOT00000090666 ENSRNOT00000032783	Dmgdh NCBI RGD Ensembl Show fit	dimethylglycine dehydrogenase
chr4_-_161850875 Show fit	53.17	ENSRNOT00000009467	Pzp NCBI RGD Ensembl Show fit	pregnancy-zone protein
chr15_+_18451144 Show fit	51.56	ENSRNOT00000010260	Acox2 NCBI RGD Ensembl Show fit	acyl-CoA oxidase 2
chr9_-_4945352 Show fit	51.45	ENSRNOT00000082530	Sult1c3 NCBI RGD Ensembl Show fit	sulfotransferase family 1C member 3
chr4_-_115332052 Show fit	50.04	ENSRNOT00000017643	Clec4f NCBI RGD Ensembl Show fit	C-type lectin domain family 4, member F
chr17_+_9736577 Show fit	46.18	ENSRNOT00000066586	F12 NCBI RGD Ensembl Show fit	coagulation factor XII
chr10_+_65767053 Show fit	45.18	ENSRNOT00000078897	Vtn NCBI RGD Ensembl Show fit	vitronectin
chr17_-_69711689 Show fit	44.72	ENSRNOT00000041925	Akr1c12 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C12
chr13_-_47397890 Show fit	44.47	ENSRNOT00000005505	C4bpb NCBI RGD Ensembl Show fit	complement component 4 binding protein, beta
chr19_-_50220455 Show fit	44.18	ENSRNOT00000079760	Sdr42e1 NCBI RGD Ensembl Show fit	short chain dehydrogenase/reductase family 42E, member 1
chr6_-_127534247 Show fit	43.11	ENSRNOT00000012500	Serpina6 NCBI RGD Ensembl Show fit	serpin family A member 6
chr7_-_71139267 Show fit	41.48	ENSRNOT00000065232	RGD1561812 NCBI RGD Ensembl Show fit	similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr1_+_147713892 Show fit	41.10	ENSRNOT00000092985 ENSRNOT00000054742 ENSRNOT00000074103	Cyp2c6v1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr4_-_50200328 Show fit	40.19	ENSRNOT00000060530	Aass NCBI RGD Ensembl Show fit	aminoadipate-semialdehyde synthase
chr7_-_129970550 Show fit	37.84	ENSRNOT00000055879	Mlc1 NCBI RGD Ensembl Show fit	megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_-_127620296 Show fit	37.46	ENSRNOT00000012577	Serpina1 NCBI RGD Ensembl Show fit	serpin family A member 1
chr2_-_180914940 Show fit	37.38	ENSRNOT00000015732	Tdo2 NCBI RGD Ensembl Show fit	tryptophan 2,3-dioxygenase
chr16_+_18690649 Show fit	37.14	ENSRNOT00000015190	Mat1a NCBI RGD Ensembl Show fit	methionine adenosyltransferase 1A
chrX_+_143097525 Show fit	35.55	ENSRNOT00000004559	F9 NCBI RGD Ensembl Show fit	coagulation factor IX
chr7_-_27552078 Show fit	35.23	ENSRNOT00000059538	Stab2 NCBI RGD Ensembl Show fit	stabilin 2
chr5_+_124300477 Show fit	34.46	ENSRNOT00000010100	C8b NCBI RGD Ensembl Show fit	complement C8 beta chain
chr5_-_124403195 Show fit	33.94	ENSRNOT00000067850	C8a NCBI RGD Ensembl Show fit	complement C8 alpha chain
chr17_-_69404323 Show fit	33.86	ENSRNOT00000051342 ENSRNOT00000066282	Akr1c2 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C2
chr5_+_134492756 Show fit	33.83	ENSRNOT00000012888 ENSRNOT00000057095 ENSRNOT00000051385	Cyp4a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 4, subfamily a, polypeptide 1
chr14_+_22724399 Show fit	32.78	ENSRNOT00000002724	Ugt2b10 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide B10
chr6_+_128050250 Show fit	32.02	ENSRNOT00000077517 ENSRNOT00000013961	LOC500712 NCBI RGD Ensembl Show fit	Ab1-233
chr14_+_22553650 Show fit	31.51	ENSRNOT00000092201 ENSRNOT00000002712	Ugt2b35 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide B35
chr1_-_258877045 Show fit	31.36	ENSRNOT00000071633	Cyp2c13 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 13
chr4_-_123557501 Show fit	30.99	ENSRNOT00000075042 ENSRNOT00000085966	Aldh1l1 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase 1 family, member L1
chr8_-_50526843 Show fit	29.95	ENSRNOT00000092188	AABR07070085.1 NCBI RGD Ensembl Show fit
chr2_+_55775274 Show fit	29.73	ENSRNOT00000018545	C9 NCBI RGD Ensembl Show fit	complement C9
chr7_+_34326087 Show fit	29.66	ENSRNOT00000006971	Hal NCBI RGD Ensembl Show fit	histidine ammonia lyase
chr9_+_100281339 Show fit	29.33	ENSRNOT00000029127	Agxt NCBI RGD Ensembl Show fit	alanine-glyoxylate aminotransferase
chr15_+_57290849 Show fit	29.16	ENSRNOT00000014909	Cpb2 NCBI RGD Ensembl Show fit	carboxypeptidase B2
chr17_-_43584152 Show fit	29.14	ENSRNOT00000023241	Slc17a2 NCBI RGD Ensembl Show fit	solute carrier family 17, member 2
chr9_-_4978892 Show fit	28.38	ENSRNOT00000015189	Sult1c3 NCBI RGD Ensembl Show fit	sulfotransferase family 1C member 3
chr9_+_6970507 Show fit	28.27	ENSRNOT00000079488	St6gal2 NCBI RGD Ensembl Show fit	ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr2_+_114413410 Show fit	26.99	ENSRNOT00000015866	Slc2a2 NCBI RGD Ensembl Show fit	solute carrier family 2 member 2
chr8_-_50539331 Show fit	26.67	ENSRNOT00000088997	AABR07073400.1 NCBI RGD Ensembl Show fit
chr2_+_20857202 Show fit	26.57	ENSRNOT00000078919	Acot12 NCBI RGD Ensembl Show fit	acyl-CoA thioesterase 12
chr13_+_51534025 Show fit	26.14	ENSRNOT00000006637	Syt2 NCBI RGD Ensembl Show fit	synaptotagmin 2
chr1_+_213577122 Show fit	25.40	ENSRNOT00000071925	RGD1309350 NCBI RGD Ensembl Show fit	similar to transthyretin (4L369)
chr3_+_56861396 Show fit	25.36	ENSRNOT00000000008 ENSRNOT00000084375	Gad1 NCBI RGD Ensembl Show fit	glutamate decarboxylase 1
chr10_+_66942398 Show fit	25.33	ENSRNOT00000018986	Rab11fip4 NCBI RGD Ensembl Show fit	RAB11 family interacting protein 4
chr1_+_189364288 Show fit	25.27	ENSRNOT00000080338	Acsm1 NCBI RGD Ensembl Show fit	acyl-CoA synthetase medium-chain family member 1
chr1_-_221431713 Show fit	25.07	ENSRNOT00000028485	Tm7sf2 NCBI RGD Ensembl Show fit	transmembrane 7 superfamily member 2
chr10_+_65767930 Show fit	25.03	ENSRNOT00000039954	Vtn NCBI RGD Ensembl Show fit	vitronectin
chr12_-_19114399 Show fit	24.83	ENSRNOT00000073099	Cyp3a9 NCBI RGD Ensembl Show fit	cytochrome P450, family 3, subfamily a, polypeptide 9
chr1_-_258766881 Show fit	24.74	ENSRNOT00000015801	Cyp2c12 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 12
chr5_-_77433847 Show fit	24.71	ENSRNOT00000076906 ENSRNOT00000043056	LOC500473 NCBI RGD Ensembl Show fit Mup4 NCBI RGD Ensembl Show fit	similar to alpha-2u globulin PGCL2 major urinary protein 4
chr11_+_74057361 Show fit	23.79	ENSRNOT00000048746	Cpn2 NCBI RGD Ensembl Show fit	carboxypeptidase N subunit 2
chr10_-_71491743 Show fit	22.86	ENSRNOT00000038955	LOC102552988 NCBI RGD Ensembl Show fit	uncharacterized LOC102552988
chr11_+_7422272 Show fit	22.48	ENSRNOT00000075964	Gbe1 NCBI RGD Ensembl Show fit	1,4-alpha-glucan branching enzyme 1
chr5_-_173233188 Show fit	22.46	ENSRNOT00000055343	Tmem88b NCBI RGD Ensembl Show fit	transmembrane protein 88B
chr4_+_153921900 Show fit	22.13	ENSRNOT00000089482	Slc6a12 NCBI RGD Ensembl Show fit	solute carrier family 6 member 12
chr10_-_103340922 Show fit	21.83	ENSRNOT00000004191	Btbd17 NCBI RGD Ensembl Show fit	BTB domain containing 17
chr4_-_62840357 Show fit	21.82	ENSRNOT00000059892	Slc13a4 NCBI RGD Ensembl Show fit	solute carrier family 13 member 4
chr11_-_60882379 Show fit	21.63	ENSRNOT00000002799	Cd200r1 NCBI RGD Ensembl Show fit	CD200 receptor 1
chr6_+_132242328 Show fit	21.20	ENSRNOT00000081088	Cyp46a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 46, subfamily a, polypeptide 1
chr5_+_142875773 Show fit	21.20	ENSRNOT00000082120 ENSRNOT00000056496	Epha10 NCBI RGD Ensembl Show fit	EPH receptor A10
chr9_-_19880346 Show fit	21.17	ENSRNOT00000014051	Cyp39a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 39, subfamily a, polypeptide 1
chr6_+_111176798 Show fit	21.14	ENSRNOT00000072215	Gstz1 NCBI RGD Ensembl Show fit	glutathione S-transferase zeta 1
chr5_-_140657745 Show fit	20.95	ENSRNOT00000019080	Mfsd2a NCBI RGD Ensembl Show fit	major facilitator superfamily domain containing 2A
chr17_+_31441630 Show fit	20.90	ENSRNOT00000083705 ENSRNOT00000023582	Tubb2b NCBI RGD Ensembl Show fit	tubulin, beta 2B class IIb
chr3_-_127500709 Show fit	20.83	ENSRNOT00000006330	Hao1 NCBI RGD Ensembl Show fit	hydroxyacid oxidase 1
chr5_-_4975436 Show fit	20.83	ENSRNOT00000062006	Xkr9 NCBI RGD Ensembl Show fit	XK related 9
chr5_-_77903062 Show fit	20.73	ENSRNOT00000073954 ENSRNOT00000059320 ENSRNOT00000089382 ENSRNOT00000076074 ENSRNOT00000074349	LOC100912565 NCBI RGD Ensembl Show fit Rn50_5_0814.4 NCBI RGD Ensembl Show fit	major urinary protein-like alpha2u globulin (LOC298111), mRNA
chr4_+_109497962 Show fit	20.69	ENSRNOT00000057869	Reg1a NCBI RGD Ensembl Show fit	regenerating family member 1 alpha
chr8_-_46537050 Show fit	19.87	ENSRNOT00000011284	Sc5d NCBI RGD Ensembl Show fit	sterol-C5-desaturase
chr4_+_57952982 Show fit	19.80	ENSRNOT00000014465	Cpa1 NCBI RGD Ensembl Show fit	carboxypeptidase A1
chr14_+_22251499 Show fit	19.31	ENSRNOT00000087991 ENSRNOT00000002705	Ugt2a1 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase 2 family, polypeptide A1
chr3_-_7141522 Show fit	18.80	ENSRNOT00000014572	Cel NCBI RGD Ensembl Show fit	carboxyl ester lipase
chr2_+_150146234 Show fit	18.70	ENSRNOT00000018761	Aadac NCBI RGD Ensembl Show fit	arylacetamide deacetylase
chr1_+_100393303 Show fit	18.62	ENSRNOT00000026251	Syt3 NCBI RGD Ensembl Show fit	synaptotagmin 3
chr4_-_77489535 Show fit	18.33	ENSRNOT00000008728	Pdia4 NCBI RGD Ensembl Show fit	protein disulfide isomerase family A, member 4
chr2_+_235264219 Show fit	18.21	ENSRNOT00000086245	Cfi NCBI RGD Ensembl Show fit	complement factor I
chr17_-_69827112 Show fit	18.17	ENSRNOT00000023835	Akr1c14 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C14
chr1_-_85220237 Show fit	17.75	ENSRNOT00000026907	Sycn NCBI RGD Ensembl Show fit	syncollin
chr2_-_53140637 Show fit	17.68	ENSRNOT00000060492	Ccdc152 NCBI RGD Ensembl Show fit	coiled-coil domain containing 152
chr4_+_175729726 Show fit	17.55	ENSRNOT00000013230	Slco1c1 NCBI RGD Ensembl Show fit	solute carrier organic anion transporter family, member 1c1
chr5_-_77342299 Show fit	17.29	ENSRNOT00000075994	RGD1566134 NCBI RGD Ensembl Show fit	similar to alpha-2u-globulin
chr4_+_153921115 Show fit	17.23	ENSRNOT00000018821	Slc6a12 NCBI RGD Ensembl Show fit	solute carrier family 6 member 12
chr3_+_117416345 Show fit	16.98	ENSRNOT00000056054	Ctxn2 NCBI RGD Ensembl Show fit	cortexin 2
chr11_-_64421248 Show fit	16.77	ENSRNOT00000066997	Igsf11 NCBI RGD Ensembl Show fit	immunoglobulin superfamily, member 11
chr7_-_106753592 Show fit	16.71	ENSRNOT00000006930	Kcnq3 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily Q member 3
chr9_+_95256627 Show fit	16.46	ENSRNOT00000025291	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr3_+_134440195 Show fit	16.43	ENSRNOT00000072928	AABR07054000.1 NCBI RGD Ensembl Show fit
chrX_+_118084890 Show fit	16.12	ENSRNOT00000065293	Htr2c NCBI RGD Ensembl Show fit	5-hydroxytryptamine receptor 2C
chr5_+_124476168 Show fit	15.96	ENSRNOT00000077754	RGD1564074 NCBI RGD Ensembl Show fit	similar to novel protein
chr15_+_42659371 Show fit	15.83	ENSRNOT00000091612	Clu NCBI RGD Ensembl Show fit	clusterin
chr14_+_2050483 Show fit	15.56	ENSRNOT00000000047	Slc26a1 NCBI RGD Ensembl Show fit	solute carrier family 26 member 1
chr7_-_12246729 Show fit	15.49	ENSRNOT00000044030	Reep6 NCBI RGD Ensembl Show fit	receptor accessory protein 6
chr4_+_84423653 Show fit	15.32	ENSRNOT00000012655	Chn2 NCBI RGD Ensembl Show fit	chimerin 2
chr9_+_95285592 Show fit	15.23	ENSRNOT00000063853	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr10_+_59765258 Show fit	15.17	ENSRNOT00000026351	Shpk NCBI RGD Ensembl Show fit	sedoheptulokinase
chr16_+_3293599 Show fit	14.81	ENSRNOT00000081999 ENSRNOT00000047118 ENSRNOT00000020427	Erc2 NCBI RGD Ensembl Show fit	ELKS/RAB6-interacting/CAST family member 2
chr10_-_83898527 Show fit	14.77	ENSRNOT00000009815	Atp5g1 NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_+_154395187 Show fit	14.72	ENSRNOT00000050810	Vstm2l NCBI RGD Ensembl Show fit	V-set and transmembrane domain containing 2 like
chr5_-_58124681 Show fit	14.67	ENSRNOT00000019795	Sigmar1 NCBI RGD Ensembl Show fit	sigma non-opioid intracellular receptor 1
chr8_+_52729003 Show fit	14.62	ENSRNOT00000081738	Nxpe4 NCBI RGD Ensembl Show fit	neurexophilin and PC-esterase domain family, member 4
chr15_+_47455690 Show fit	14.30	ENSRNOT00000075276	LOC100910401 NCBI RGD Ensembl Show fit	serine protease 55-like
chr9_-_98551410 Show fit	14.28	ENSRNOT00000066346 ENSRNOT00000086678	Hes6 NCBI RGD Ensembl Show fit	hes family bHLH transcription factor 6
chr10_+_109708755 Show fit	14.21	ENSRNOT00000083601	Gcgr NCBI RGD Ensembl Show fit	glucagon receptor
chr5_-_109651730 Show fit	13.67	ENSRNOT00000093032	Elavl2 NCBI RGD Ensembl Show fit	ELAV like RNA binding protein 2
chr10_+_37215937 Show fit	13.63	ENSRNOT00000006567	Sar1b NCBI RGD Ensembl Show fit	secretion associated, Ras related GTPase 1B
chr13_-_72063347 Show fit	13.10	ENSRNOT00000090544 ENSRNOT00000003869	Cacna1e NCBI RGD Ensembl Show fit	calcium voltage-gated channel subunit alpha1 E
chr17_+_69588085 Show fit	13.06	ENSRNOT00000064884	Akr1c12l1 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C12-like 1
chr5_-_77492013 Show fit	13.04	ENSRNOT00000012293	LOC259245 NCBI RGD Ensembl Show fit	alpha-2u globulin PGCL5
chr1_-_211520699 Show fit	12.67	ENSRNOT00000009178	Stk32c NCBI RGD Ensembl Show fit	serine/threonine kinase 32C
chr12_-_52124779 Show fit	12.40	ENSRNOT00000088839	Galnt9 NCBI RGD Ensembl Show fit	polypeptide N-acetylgalactosaminyltransferase 9
chr9_+_4094995 Show fit	12.32	ENSRNOT00000089450	LOC100910057 NCBI RGD Ensembl Show fit	sulfotransferase 1C2-like
chr1_-_174119815 Show fit	12.30	ENSRNOT00000019368	Trim66 NCBI RGD Ensembl Show fit	tripartite motif-containing 66
chr15_-_14737704 Show fit	12.15	ENSRNOT00000011307	Synpr NCBI RGD Ensembl Show fit	synaptoporin
chr10_-_27366665 Show fit	12.10	ENSRNOT00000004725	Gabra1 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor alpha1 subunit
chr5_-_40237591 Show fit	12.09	ENSRNOT00000011393	Fut9 NCBI RGD Ensembl Show fit	fucosyltransferase 9
chr1_-_220096319 Show fit	12.02	ENSRNOT00000091787 ENSRNOT00000073983	Ccs NCBI RGD Ensembl Show fit	copper chaperone for superoxide dismutase
chr9_+_101005082 Show fit	11.95	ENSRNOT00000082949	Neu4 NCBI RGD Ensembl Show fit	neuraminidase 4
chr12_+_8725517 Show fit	11.88	ENSRNOT00000001243	Slc46a3 NCBI RGD Ensembl Show fit	solute carrier family 46, member 3
chrM_+_7758 Show fit	11.78	ENSRNOT00000046201	Mt-atp8 NCBI RGD Ensembl Show fit	mitochondrially encoded ATP synthase 8
chr8_+_13796021 Show fit	11.75	ENSRNOT00000013927	Vstm5 NCBI RGD Ensembl Show fit	V-set and transmembrane domain containing 5
chr1_+_167937026 Show fit	11.73	ENSRNOT00000020655	Olr57 NCBI RGD Ensembl Show fit	olfactory receptor 57
chr15_-_23969011 Show fit	11.71	ENSRNOT00000014821	Gch1 NCBI RGD Ensembl Show fit	GTP cyclohydrolase 1
chr8_+_85259982 Show fit	11.70	ENSRNOT00000010409	Elovl5 NCBI RGD Ensembl Show fit	ELOVL fatty acid elongase 5
chr10_-_65820538 Show fit	11.66	ENSRNOT00000011808	Tmem97 NCBI RGD Ensembl Show fit	transmembrane protein 97
chr1_+_42170281 Show fit	11.57	ENSRNOT00000092879	Vip NCBI RGD Ensembl Show fit	vasoactive intestinal peptide
chr2_-_188412329 Show fit	11.49	ENSRNOT00000033917 ENSRNOT00000080185	Fdps NCBI RGD Ensembl Show fit	farnesyl diphosphate synthase
chr1_+_102900286 Show fit	11.45	ENSRNOT00000017468	Ldha NCBI RGD Ensembl Show fit	lactate dehydrogenase A
chr5_+_78222504 Show fit	11.36	ENSRNOT00000019544	Slc31a1 NCBI RGD Ensembl Show fit	solute carrier family 31 member 1
chr1_+_282134981 Show fit	11.34	ENSRNOT00000036203	Nanos1 NCBI RGD Ensembl Show fit	nanos C2HC-type zinc finger 1
chr4_+_151298548 Show fit	11.24	ENSRNOT00000010746	Cacna2d4 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 4
chr1_-_5165859 Show fit	11.18	ENSRNOT00000044325 ENSRNOT00000019319	Grm1 NCBI RGD Ensembl Show fit	glutamate metabotropic receptor 1
chr13_+_83681322 Show fit	11.18	ENSRNOT00000004206	Mpc2 NCBI RGD Ensembl Show fit	mitochondrial pyruvate carrier 2
chr10_-_107539465 Show fit	11.08	ENSRNOT00000004524	Rbfox3 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 3
chr10_-_35833861 Show fit	11.05	ENSRNOT00000049942	Canx NCBI RGD Ensembl Show fit	calnexin
chr3_+_114355798 Show fit	10.98	ENSRNOT00000024658 ENSRNOT00000036435	Slc28a2 NCBI RGD Ensembl Show fit	solute carrier family 28 member 2
chr15_-_80713153 Show fit	10.94	ENSRNOT00000063800	Klhl1 NCBI RGD Ensembl Show fit	kelch-like family member 1
chr2_-_170460754 Show fit	10.90	ENSRNOT00000013009	Slitrk3 NCBI RGD Ensembl Show fit	SLIT and NTRK-like family, member 3
chr13_-_36156076 Show fit	10.89	ENSRNOT00000074685	Dbi NCBI RGD Ensembl Show fit	diazepam binding inhibitor, acyl-CoA binding protein
chr2_+_243656579 Show fit	10.78	ENSRNOT00000036993	Adh1 NCBI RGD Ensembl Show fit	alcohol dehydrogenase 1 (class I)
chr5_-_59553416 Show fit	10.76	ENSRNOT00000090490	Gne NCBI RGD Ensembl Show fit	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr10_-_8654892 Show fit	10.68	ENSRNOT00000066534	Rbfox1 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 1
chr17_+_69468427 Show fit	10.63	ENSRNOT00000058413	RGD1564865 NCBI RGD Ensembl Show fit	similar to 20-alpha-hydroxysteroid dehydrogenase
chr13_-_50514151 Show fit	10.56	ENSRNOT00000003951	Ren NCBI RGD Ensembl Show fit	renin
chr10_+_88997399 Show fit	10.53	ENSRNOT00000027116	Mlx NCBI RGD Ensembl Show fit	MLX, MAX dimerization protein
chr8_-_2045817 Show fit	10.47	ENSRNOT00000009542 ENSRNOT00000081171 ENSRNOT00000078765	Gria4 NCBI RGD Ensembl Show fit	glutamate ionotropic receptor AMPA type subunit 4
chr2_-_235177275 Show fit	10.44	ENSRNOT00000093153	LOC103691699 NCBI RGD Ensembl Show fit	uncharacterized LOC103691699
chr15_+_42640146 Show fit	10.43	ENSRNOT00000078861	Clu NCBI RGD Ensembl Show fit	clusterin
chr17_+_69761118 Show fit	10.35	ENSRNOT00000023739	Akr1c3 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C3
chr11_-_77593171 Show fit	10.29	ENSRNOT00000002645 ENSRNOT00000043498	Il1rap NCBI RGD Ensembl Show fit	interleukin 1 receptor accessory protein
chr15_-_8914501 Show fit	10.28	ENSRNOT00000008752	Thrb NCBI RGD Ensembl Show fit	thyroid hormone receptor beta
chr2_+_22909569 Show fit	10.26	ENSRNOT00000073871	Homer1 NCBI RGD Ensembl Show fit	homer scaffolding protein 1
chr4_-_121969446 Show fit	10.16	ENSRNOT00000085001	Vom1r99 NCBI RGD Ensembl Show fit	vomeronasal 1 receptor 99
chr3_-_176816114 Show fit	10.15	ENSRNOT00000079262 ENSRNOT00000018697	Stmn3 NCBI RGD Ensembl Show fit	stathmin 3
chr9_+_95241609 Show fit	10.12	ENSRNOT00000032634 ENSRNOT00000077416	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr5_-_166133274 Show fit	10.11	ENSRNOT00000078830	Kif1b NCBI RGD Ensembl Show fit	kinesin family member 1B
chr16_-_81756654 Show fit	10.08	ENSRNOT00000026653	Cul4a NCBI RGD Ensembl Show fit	cullin 4A
chr10_+_1834518 Show fit	10.06	ENSRNOT00000061709	Gm1758 NCBI RGD Ensembl Show fit	predicted gene 1758
chr14_-_46529375 Show fit	9.86	ENSRNOT00000077306 ENSRNOT00000078682	LOC257642 NCBI RGD Ensembl Show fit	rRNA promoter binding protein
chr12_-_35979193 Show fit	9.85	ENSRNOT00000071104	Tmem132b NCBI RGD Ensembl Show fit	transmembrane protein 132B
chr4_+_21462779 Show fit	9.74	ENSRNOT00000089747	Grm3 NCBI RGD Ensembl Show fit	glutamate metabotropic receptor 3
chr9_-_91882927 Show fit	9.73	ENSRNOT00000084446	Pid1 NCBI RGD Ensembl Show fit	phosphotyrosine interaction domain containing 1
chr3_+_11593655 Show fit	9.70	ENSRNOT00000074122	Pip5kl1 NCBI RGD Ensembl Show fit	phosphatidylinositol-4-phosphate 5-kinase-like 1
chr13_+_77485113 Show fit	9.70	ENSRNOT00000080254	Tnr NCBI RGD Ensembl Show fit	tenascin R
chr10_+_91187593 Show fit	9.68	ENSRNOT00000004163	Acbd4 NCBI RGD Ensembl Show fit	acyl-CoA binding domain containing 4
chr10_-_15465404 Show fit	9.66	ENSRNOT00000077826 ENSRNOT00000027593	Decr2 NCBI RGD Ensembl Show fit	2,4-dienoyl-CoA reductase 2
chr20_+_41100071 Show fit	9.59	ENSRNOT00000000658	Tspyl4 NCBI RGD Ensembl Show fit	TSPY-like 4
chr3_+_177310753 Show fit	9.43	ENSRNOT00000031448	Myt1 NCBI RGD Ensembl Show fit	myelin transcription factor 1
chr2_+_209840404 Show fit	9.39	ENSRNOT00000050149	Kcna2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A member 2
chr2_-_2814690 Show fit	9.33	ENSRNOT00000029265	Gpr150 NCBI RGD Ensembl Show fit	G protein-coupled receptor 150
chr10_-_37215899 Show fit	9.31	ENSRNOT00000006356	Sec24a NCBI RGD Ensembl Show fit	SEC24 homolog A, COPII coat complex component
chr1_-_264172729 Show fit	9.25	ENSRNOT00000018447	Scd NCBI RGD Ensembl Show fit	stearoyl-CoA desaturase
chr10_-_96131880 Show fit	9.09	ENSRNOT00000004578	Cacng5 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 5
chrX_+_65800059 Show fit	9.09	ENSRNOT00000076428	Gpr165 NCBI RGD Ensembl Show fit	G protein-coupled receptor 165
chr1_-_128604188 Show fit	9.05	ENSRNOT00000033858	Lrrc28 NCBI RGD Ensembl Show fit	leucine rich repeat containing 28
chr1_+_67025240 Show fit	9.05	ENSRNOT00000051024	Vom1r47 NCBI RGD Ensembl Show fit	vomeronasal 1 receptor 47
chr1_-_82344345 Show fit	9.04	ENSRNOT00000051892 ENSRNOT00000090629 ENSRNOT00000029487 ENSRNOT00000027933	Ceacam1 NCBI RGD Ensembl Show fit	carcinoembryonic antigen related cell adhesion molecule 1
chr13_-_44345735 Show fit	9.04	ENSRNOT00000005006	Tmem163 NCBI RGD Ensembl Show fit	transmembrane protein 163
chr17_+_81455955 Show fit	8.98	ENSRNOT00000044313	Slc39a12 NCBI RGD Ensembl Show fit	solute carrier family 39 member 12
chr10_-_107539658 Show fit	8.97	ENSRNOT00000089346	Rbfox3 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 3
chr16_-_10603850 Show fit	8.96	ENSRNOT00000087737	Fam35a NCBI RGD Ensembl Show fit	family with sequence similarity 35, member A
chr13_-_39643361 Show fit	8.92	ENSRNOT00000003527	Dpp10 NCBI RGD Ensembl Show fit	dipeptidylpeptidase 10
chr5_+_135029955 Show fit	8.91	ENSRNOT00000074860	LOC100911669 NCBI RGD Ensembl Show fit	uncharacterized LOC100911669
chr6_+_97168453 Show fit	8.90	ENSRNOT00000085790	Syt16 NCBI RGD Ensembl Show fit	synaptotagmin 16
chr18_+_62805410 Show fit	8.88	ENSRNOT00000086679	Gnal NCBI RGD Ensembl Show fit	G protein subunit alpha L
chr13_-_51076852 Show fit	8.80	ENSRNOT00000078993	Adora1 NCBI RGD Ensembl Show fit	adenosine A1 receptor
chrX_+_28072826 Show fit	8.79	ENSRNOT00000039796	Frmpd4 NCBI RGD Ensembl Show fit	FERM and PDZ domain containing 4
chr12_+_11814071 Show fit	8.70	ENSRNOT00000039149	Tmem130 NCBI RGD Ensembl Show fit	transmembrane protein 130
chr6_-_115616766 Show fit	8.66	ENSRNOT00000006143 ENSRNOT00000045870	Sel1l NCBI RGD Ensembl Show fit	SEL1L ERAD E3 ligase adaptor subunit
chr2_+_228544418 Show fit	8.64	ENSRNOT00000013030	Tram1l1 NCBI RGD Ensembl Show fit	translocation associated membrane protein 1-like 1
chrX_-_15707436 Show fit	8.62	ENSRNOT00000085907	Syp NCBI RGD Ensembl Show fit	synaptophysin
chr9_+_73528681 Show fit	8.47	ENSRNOT00000084340	Unc80 NCBI RGD Ensembl Show fit	unc-80 homolog, NALCN activator
chr4_+_22859622 Show fit	8.46	ENSRNOT00000073501 ENSRNOT00000068410	Adam22 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 22
chr1_-_213635546 Show fit	8.45	ENSRNOT00000018861	Sirt3 NCBI RGD Ensembl Show fit	sirtuin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Cux1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
36.4	109.2	GO:0002254	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
18.3	127.9	GO:0009804	coumarin metabolic process(GO:0009804)
17.8	53.5	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
17.2	51.6	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
14.8	44.5	GO:0045959	negative regulation of complement activation, classical pathway(GO:0045959)
14.7	44.2	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
13.4	40.2	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
12.5	37.5	GO:0033986	response to methanol(GO:0033986)
10.3	31.0	GO:0042560	folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
10.3	41.1	GO:0016098	monoterpenoid metabolic process(GO:0016098)
9.9	29.7	GO:0019556	formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
9.8	39.4	GO:0009992	cellular water homeostasis(GO:0009992)
9.8	29.3	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) oxalic acid secretion(GO:0046724)
9.7	29.2	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
8.8	26.3	GO:1902847	regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
8.5	33.8	GO:0048252	lauric acid metabolic process(GO:0048252)
8.3	24.8	GO:0009822	lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
8.0	8.0	GO:0010877	lipid transport involved in lipid storage(GO:0010877)
7.2	35.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
7.0	21.0	GO:0051977	lysophospholipid transport(GO:0051977)
6.9	20.7	GO:1990869	response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
6.7	133.2	GO:0019373	epoxygenase P450 pathway(GO:0019373)
6.4	64.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
6.4	70.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
6.2	37.4	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
5.8	57.9	GO:0018298	protein-chromophore linkage(GO:0018298)
5.7	28.3	GO:0015755	fructose transport(GO:0015755)
5.4	16.1	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
5.3	15.9	GO:1901143	insulin catabolic process(GO:1901143)
5.2	20.8	GO:0009441	glycolate metabolic process(GO:0009441)
5.1	25.4	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
4.9	64.3	GO:0052695	cellular glucuronidation(GO:0052695)
4.6	18.3	GO:1903334	positive regulation of protein folding(GO:1903334)
4.5	50.0	GO:0051132	NK T cell activation(GO:0051132)
4.4	61.2	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
3.9	11.7	GO:0014916	regulation of lung blood pressure(GO:0014916)
3.7	11.2	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
3.6	10.8	GO:0006117	acetaldehyde metabolic process(GO:0006117)
3.6	10.8	GO:0046380	N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
3.5	21.1	GO:0006572	tyrosine catabolic process(GO:0006572)
3.4	10.3	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
3.3	3.3	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518)
3.2	37.8	GO:0047484	regulation of response to osmotic stress(GO:0047484)
3.1	9.3	GO:1903699	tarsal gland development(GO:1903699)
2.9	8.8	GO:0032900	regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) negative regulation of long term synaptic depression(GO:1900453)
2.9	8.6	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
2.8	11.4	GO:0098705	copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
2.8	14.2	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
2.8	8.3	GO:0033693	neurofilament bundle assembly(GO:0033693)
2.7	10.9	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
2.6	10.6	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
2.6	7.8	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
2.5	25.3	GO:0070314	G1 to G0 transition(GO:0070314)
2.5	47.2	GO:0042359	vitamin D metabolic process(GO:0042359)
2.5	7.4	GO:0098749	cerebellar neuron development(GO:0098749)
2.4	14.7	GO:0038003	opioid receptor signaling pathway(GO:0038003)
2.4	7.3	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.4	9.7	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
2.3	11.7	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.3	18.7	GO:0070459	prolactin secretion(GO:0070459)
2.3	2.3	GO:0090032	negative regulation of steroid hormone biosynthetic process(GO:0090032)
2.3	38.7	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
2.3	24.8	GO:0070327	thyroid hormone transport(GO:0070327)
2.3	13.5	GO:0015860	purine nucleoside transmembrane transport(GO:0015860)
2.2	15.6	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
2.2	6.5	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
2.0	10.1	GO:0019520	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
2.0	6.0	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
2.0	10.0	GO:0033384	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
2.0	6.0	GO:0010034	response to acetate(GO:0010034)
2.0	6.0	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
1.9	34.4	GO:0097503	sialylation(GO:0097503)
1.9	5.7	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
1.9	11.4	GO:0006113	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.9	5.7	GO:0030091	protein repair(GO:0030091)
1.9	3.8	GO:1905232	cellular response to L-glutamate(GO:1905232)
1.9	5.7	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.9	18.7	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
1.8	12.5	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
1.8	3.5	GO:0006553	lysine metabolic process(GO:0006553)
1.7	8.7	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
1.7	10.3	GO:0008050	female courtship behavior(GO:0008050)
1.7	8.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
1.6	6.6	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
1.6	8.2	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
1.6	13.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
1.6	9.8	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
1.6	9.7	GO:0048686	regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.6	8.0	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.6	49.8	GO:1903861	positive regulation of dendrite extension(GO:1903861)
1.6	4.7	GO:0002086	diaphragm contraction(GO:0002086)
1.6	9.4	GO:0021633	optic nerve structural organization(GO:0021633)
1.6	39.0	GO:0008211	glucocorticoid metabolic process(GO:0008211)
1.6	9.3	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
1.5	3.0	GO:0097187	dentinogenesis(GO:0097187)
1.5	8.7	GO:0051182	coenzyme transport(GO:0051182)
1.4	4.3	GO:0016267	O-glycan processing, core 1(GO:0016267)
1.4	55.5	GO:0006956	complement activation(GO:0006956)
1.4	6.9	GO:0048105	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.4	5.5	GO:0014028	notochord formation(GO:0014028)
1.4	6.8	GO:1900620	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
1.3	6.7	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
1.3	3.9	GO:0001966	thigmotaxis(GO:0001966)
1.3	14.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
1.3	3.8	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.3	8.9	GO:0009405	pathogenesis(GO:0009405)
1.3	3.8	GO:0009227	nucleotide-sugar catabolic process(GO:0009227)
1.3	3.8	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
1.2	2.5	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
1.2	6.1	GO:0002317	plasma cell differentiation(GO:0002317)
1.2	4.9	GO:0006564	L-serine biosynthetic process(GO:0006564)
1.2	29.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
1.2	15.6	GO:0019532	oxalate transport(GO:0019532)
1.2	4.7	GO:0006285	base-excision repair, AP site formation(GO:0006285)
1.2	8.2	GO:0042420	dopamine catabolic process(GO:0042420)
1.2	8.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.2	2.3	GO:0006004	fucose metabolic process(GO:0006004)
1.1	21.8	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.1	7.7	GO:2000819	regulation of nucleotide-excision repair(GO:2000819)
1.1	29.0	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
1.1	3.2	GO:0035928	rRNA import into mitochondrion(GO:0035928)
1.1	9.5	GO:0006689	ganglioside catabolic process(GO:0006689)
1.0	7.3	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
1.0	9.4	GO:0060539	diaphragm development(GO:0060539)
1.0	8.4	GO:0007262	STAT protein import into nucleus(GO:0007262)
1.0	3.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
1.0	5.1	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
1.0	5.1	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
1.0	12.1	GO:0071420	cellular response to histamine(GO:0071420)
1.0	3.9	GO:0018963	phthalate metabolic process(GO:0018963)
1.0	2.0	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.0	44.6	GO:0016126	sterol biosynthetic process(GO:0016126)
1.0	9.7	GO:0006228	UTP biosynthetic process(GO:0006228)
0.9	3.8	GO:0071283	cellular response to iron(III) ion(GO:0071283)
0.9	2.8	GO:0045054	constitutive secretory pathway(GO:0045054)
0.9	4.7	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.9	3.7	GO:0071926	endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.9	2.8	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.9	5.5	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.9	2.7	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.9	2.7	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
0.9	5.4	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.9	3.6	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.9	9.8	GO:0035095	behavioral response to nicotine(GO:0035095)
0.9	4.4	GO:0035627	ceramide transport(GO:0035627)
0.9	3.5	GO:0006824	cobalt ion transport(GO:0006824)
0.9	25.4	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.9	8.7	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.9	12.1	GO:0036065	fucosylation(GO:0036065)
0.9	1.7	GO:1902741	type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.8	8.5	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.8	0.8	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.8	9.0	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.8	2.4	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
0.8	6.3	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.8	45.8	GO:0007566	embryo implantation(GO:0007566)
0.8	2.4	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.8	6.2	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8	13.8	GO:0001675	acrosome assembly(GO:0001675)
0.8	16.7	GO:0061548	ganglion development(GO:0061548)
0.7	6.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.7	3.7	GO:0071418	cellular response to amine stimulus(GO:0071418)
0.7	6.6	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.7	7.3	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.7	5.8	GO:1990034	calcium ion export from cell(GO:1990034)
0.7	3.5	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.7	2.1	GO:2000853	negative regulation of corticosterone secretion(GO:2000853)
0.7	8.0	GO:0007340	acrosome reaction(GO:0007340)
0.6	3.1	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.6	17.8	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.6	1.8	GO:0060125	pancreatic amylase secretion(GO:0036395) negative regulation of growth hormone secretion(GO:0060125) regulation of pancreatic amylase secretion(GO:1902276)
0.6	7.8	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6	5.4	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.6	1.8	GO:0090648	response to environmental enrichment(GO:0090648)
0.6	10.7	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.6	5.3	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.6	2.9	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.6	6.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6	2.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.6	17.3	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.6	3.3	GO:0071569	protein ufmylation(GO:0071569)
0.6	2.8	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
0.5	10.4	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.5	9.1	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5	4.8	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5	1.6	GO:0016240	autophagosome docking(GO:0016240)
0.5	1.6	GO:2000464	positive regulation of astrocyte chemotaxis(GO:2000464)
0.5	8.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.5	4.5	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.5	2.0	GO:1901318	negative regulation of sperm motility(GO:1901318)
0.5	1.5	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.5	2.4	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.5	1.5	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.5	3.9	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5	12.0	GO:0019430	removal of superoxide radicals(GO:0019430)
0.5	6.7	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.5	1.4	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.5	3.7	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.5	3.6	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.4	2.2	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.4	0.9	GO:1904954	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.4	2.6	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4	11.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4	6.8	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.4	2.9	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.4	35.2	GO:1900046	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.4	16.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4	4.8	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.4	2.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.4	1.9	GO:0032918	polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) spermine catabolic process(GO:0046208)
0.4	5.3	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.4	1.9	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.4	17.1	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.4	3.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.4	6.5	GO:0006020	inositol metabolic process(GO:0006020)
0.4	2.9	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.4	1.4	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4	8.5	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3	4.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.3	4.5	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3	4.8	GO:0048240	sperm capacitation(GO:0048240)
0.3	65.7	GO:0006790	sulfur compound metabolic process(GO:0006790)
0.3	9.7	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.3	5.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.3	13.4	GO:0033627	cell adhesion mediated by integrin(GO:0033627)
0.3	0.3	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.3	28.5	GO:0007596	blood coagulation(GO:0007596)
0.3	0.9	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.3	9.8	GO:0009303	rRNA transcription(GO:0009303)
0.3	3.1	GO:0070995	NADPH oxidation(GO:0070995)
0.3	11.5	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.3	1.2	GO:0015879	carnitine transport(GO:0015879)
0.3	1.2	GO:0002188	translation reinitiation(GO:0002188)
0.3	2.6	GO:0050957	equilibrioception(GO:0050957)
0.3	1.4	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3	5.3	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.3	3.9	GO:0007256	activation of JNKK activity(GO:0007256)
0.3	1.9	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.3	1.6	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.3	1.3	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.3	5.2	GO:0032098	regulation of appetite(GO:0032098)
0.3	4.4	GO:0043248	proteasome assembly(GO:0043248)
0.3	1.5	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.3	1.5	GO:0019348	dolichol metabolic process(GO:0019348)
0.3	5.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.3	3.5	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.2	1.2	GO:0007000	nucleolus organization(GO:0007000)
0.2	3.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.2	3.6	GO:0031167	rRNA methylation(GO:0031167)
0.2	3.5	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2	3.0	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2	4.1	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.2	2.3	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2	1.8	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.2	2.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2	5.0	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	3.4	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.2	6.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.2	254.2	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2	0.4	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2	0.9	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2	0.6	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2	9.4	GO:0042632	cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.2	12.5	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.2	1.6	GO:0051597	response to methylmercury(GO:0051597)
0.2	6.2	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2	4.8	GO:0007628	adult walking behavior(GO:0007628)
0.2	9.0	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.2	5.2	GO:0018345	protein palmitoylation(GO:0018345)
0.2	2.3	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.2	1.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.2	4.7	GO:2001240	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2	0.8	GO:0000066	mitochondrial ornithine transport(GO:0000066)
0.2	4.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.2	3.9	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.1	2.2	GO:0032801	receptor catabolic process(GO:0032801)
0.1	0.6	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	1.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.4	GO:0032197	transposition, RNA-mediated(GO:0032197)
0.1	0.6	GO:0090181	regulation of cholesterol metabolic process(GO:0090181)
0.1	1.6	GO:0044804	nucleophagy(GO:0044804)
0.1	1.3	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	1.1	GO:0048820	hair follicle maturation(GO:0048820)
0.1	0.6	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	2.4	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.1	1.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.8	GO:1990173	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1	7.5	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.1	0.5	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.1	4.8	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.1	1.0	GO:0000338	protein deneddylation(GO:0000338)
0.1	0.4	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1	1.3	GO:0015671	gas transport(GO:0015669) oxygen transport(GO:0015671)
0.1	1.7	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	1.8	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.1	0.7	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.8	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.1	0.7	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1	0.7	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1	0.9	GO:0042407	cristae formation(GO:0042407)
0.1	3.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	6.0	GO:0030901	midbrain development(GO:0030901)
0.1	0.3	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.1	2.4	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	0.5	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.1	1.3	GO:0006379	mRNA cleavage(GO:0006379)
0.1	0.4	GO:0007097	nuclear migration(GO:0007097)
0.1	0.2	GO:2000292	regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1	0.9	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1	0.9	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.1	1.5	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.1	0.2	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	1.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	2.4	GO:0051289	protein homotetramerization(GO:0051289)
0.0	1.6	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.0	0.3	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	1.4	GO:0044380	protein localization to cytoskeleton(GO:0044380)
0.0	0.0	GO:0042663	regulation of endodermal cell fate specification(GO:0042663) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0	1.4	GO:0001942	hair follicle development(GO:0001942)
0.0	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	1.3	GO:0007601	visual perception(GO:0007601)
0.0	0.4	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.1	GO:0048671	negative regulation of collateral sprouting(GO:0048671)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.0	98.1	GO:0005579	membrane attack complex(GO:0005579)
11.7	70.2	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
5.2	15.5	GO:0044317	rod spherule(GO:0044317)
4.8	52.4	GO:0042583	chromaffin granule(GO:0042583)
2.9	8.7	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
2.8	17.0	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
2.8	11.2	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
2.8	8.3	GO:0033596	TSC1-TSC2 complex(GO:0033596)
2.4	7.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.4	47.1	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
2.3	6.9	GO:0060187	cell pole(GO:0060187)
2.2	6.5	GO:0071942	XPC complex(GO:0071942)
2.1	44.5	GO:0044216	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
2.1	27.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.9	9.7	GO:0072534	perineuronal net(GO:0072534)
1.7	18.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
1.6	6.3	GO:0001405	presequence translocase-associated import motor(GO:0001405)
1.5	7.7	GO:1990769	proximal neuron projection(GO:1990769)
1.4	29.9	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.2	4.8	GO:1990630	IRE1-RACK1-PP2A complex(GO:1990630)
1.2	7.0	GO:0002142	stereocilia ankle link complex(GO:0002142)
1.1	11.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.1	10.0	GO:0071821	FANCM-MHF complex(GO:0071821)
1.1	11.0	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
1.1	10.7	GO:0030891	VCB complex(GO:0030891)
1.1	18.2	GO:0032279	asymmetric synapse(GO:0032279)
1.0	5.1	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
1.0	124.2	GO:0072562	blood microparticle(GO:0072562)
0.9	26.1	GO:0042588	zymogen granule(GO:0042588)
0.9	3.5	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.8	2.5	GO:0034457	Mpp10 complex(GO:0034457)
0.8	4.8	GO:0036128	CatSper complex(GO:0036128)
0.8	40.3	GO:0048786	presynaptic active zone(GO:0048786)
0.7	113.6	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.7	19.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.7	2.8	GO:0035339	SPOTS complex(GO:0035339)
0.7	8.2	GO:0016600	flotillin complex(GO:0016600)
0.7	11.4	GO:0035686	sperm fibrous sheath(GO:0035686)
0.7	15.7	GO:0043194	axon initial segment(GO:0043194)
0.6	1.2	GO:0099522	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.6	28.1	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6	12.1	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.6	36.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.6	9.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.5	9.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.5	6.0	GO:0008385	IkappaB kinase complex(GO:0008385)
0.5	20.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.5	7.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.5	3.8	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5	9.7	GO:0097449	astrocyte projection(GO:0097449)
0.5	1.5	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.5	7.0	GO:0043196	varicosity(GO:0043196)
0.5	2.5	GO:0002081	outer acrosomal membrane(GO:0002081)
0.5	361.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.5	9.0	GO:0031528	microvillus membrane(GO:0031528)
0.4	1.8	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.4	2.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.4	12.6	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4	3.2	GO:0000815	ESCRT III complex(GO:0000815)
0.4	1.6	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4	9.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.4	3.9	GO:0071439	clathrin complex(GO:0071439)
0.3	27.9	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.3	1.6	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.3	2.6	GO:0031083	BLOC-1 complex(GO:0031083)
0.3	4.6	GO:0030057	desmosome(GO:0030057)
0.3	18.9	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.3	6.5	GO:0033391	chromatoid body(GO:0033391)
0.3	28.4	GO:0030658	transport vesicle membrane(GO:0030658)
0.3	1.3	GO:0097422	tubular endosome(GO:0097422)
0.3	2.7	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.3	34.0	GO:0016363	nuclear matrix(GO:0016363)
0.3	1.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3	10.8	GO:0043034	costamere(GO:0043034)
0.3	1.7	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3	18.9	GO:0031526	brush border membrane(GO:0031526)
0.3	80.5	GO:0005759	mitochondrial matrix(GO:0005759)
0.3	3.9	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3	2.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.2	6.7	GO:0060170	ciliary membrane(GO:0060170)
0.2	2.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2	2.8	GO:0030666	endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.2	8.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	0.5	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.2	9.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.2	6.0	GO:0005771	multivesicular body(GO:0005771)
0.2	2.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2	3.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.2	292.6	GO:0005615	extracellular space(GO:0005615)
0.2	0.6	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2	1.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	6.1	GO:0031902	late endosome membrane(GO:0031902)
0.1	1.4	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.1	2.8	GO:0010369	chromocenter(GO:0010369)
0.1	12.2	GO:0055037	recycling endosome(GO:0055037)
0.1	7.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	2.1	GO:0045277	respiratory chain complex IV(GO:0045277)
0.1	3.6	GO:0035861	site of double-strand break(GO:0035861)
0.1	9.8	GO:0043204	perikaryon(GO:0043204)
0.1	0.5	GO:0032044	DSIF complex(GO:0032044)
0.1	2.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	10.1	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	0.7	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	5.9	GO:0045095	keratin filament(GO:0045095)
0.1	1.6	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.1	5.8	GO:0005802	trans-Golgi network(GO:0005802)
0.1	1.9	GO:0005839	proteasome core complex(GO:0005839)
0.1	1.0	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	0.8	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	3.1	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1	1.0	GO:0032039	integrator complex(GO:0032039)
0.1	0.5	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	58.3	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	72.7	GO:0005739	mitochondrion(GO:0005739)
0.1	7.9	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	0.8	GO:0016580	Sin3 complex(GO:0016580)
0.1	1.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	13.4	GO:0030424	axon(GO:0030424)
0.1	0.4	GO:0005869	dynactin complex(GO:0005869)
0.0	0.9	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	184.5	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.8	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
20.0	79.8	GO:0004027	alcohol sulfotransferase activity(GO:0004027)
15.6	62.4	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
12.5	37.4	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
12.4	37.1	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
11.7	11.7	GO:0019238	cyclohydrolase activity(GO:0019238)
11.4	57.2	GO:0019862	IgA binding(GO:0019862)
10.8	53.8	GO:0005534	galactose binding(GO:0005534)
10.3	51.6	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
10.2	335.3	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391)
9.8	49.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
9.3	56.0	GO:0005499	vitamin D binding(GO:0005499)
8.4	42.0	GO:0005550	pheromone binding(GO:0005550)
8.3	33.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
7.5	22.5	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
7.1	28.3	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
7.1	21.2	GO:0008396	oxysterol 7-alpha-hydroxylase activity(GO:0008396)
6.6	26.6	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
6.6	39.4	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
6.3	18.8	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
6.2	192.8	GO:0015020	glucuronosyltransferase activity(GO:0015020)
5.9	29.7	GO:0016841	ammonia-lyase activity(GO:0016841)
5.9	29.3	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
5.4	16.1	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
5.2	20.8	GO:0003973	(S)-2-hydroxy-acid oxidase activity(GO:0003973)
5.1	15.3	GO:0001565	phorbol ester receptor activity(GO:0001565)
5.1	25.4	GO:0004351	glutamate decarboxylase activity(GO:0004351)
4.4	31.0	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
4.2	29.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
3.6	10.9	GO:0030156	benzodiazepine receptor binding(GO:0030156)
3.6	25.4	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
3.6	10.8	GO:0009384	N-acylmannosamine kinase activity(GO:0009384)
3.6	17.8	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
3.6	14.2	GO:0004967	glucagon receptor activity(GO:0004967)
3.5	10.5	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
3.5	52.1	GO:0005542	folic acid binding(GO:0005542)
3.4	10.3	GO:0002114	interleukin-33 receptor activity(GO:0002114)
3.2	9.7	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
3.2	16.1	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
3.2	35.0	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
3.2	25.3	GO:0003996	acyl-CoA ligase activity(GO:0003996)
3.1	24.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
3.0	27.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
3.0	14.9	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
2.9	11.4	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
2.8	67.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
2.7	11.0	GO:0005415	nucleoside:sodium symporter activity(GO:0005415)
2.7	35.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
2.6	13.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
2.6	15.5	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
2.4	14.7	GO:0004985	opioid receptor activity(GO:0004985)
2.4	29.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
2.4	12.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.4	40.2	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
2.3	11.3	GO:0051185	coenzyme transporter activity(GO:0051185)
2.2	11.2	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
2.2	39.5	GO:0001848	complement binding(GO:0001848)
2.1	8.6	GO:0010465	nerve growth factor receptor activity(GO:0010465)
2.0	12.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.0	10.0	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
2.0	6.0	GO:0008384	IkappaB kinase activity(GO:0008384)
1.9	5.7	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.9	15.0	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.8	7.3	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
1.8	9.0	GO:0046790	virion binding(GO:0046790)
1.8	10.8	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.7	21.0	GO:0015245	fatty acid transporter activity(GO:0015245)
1.7	45.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
1.7	10.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.6	8.2	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
1.6	26.3	GO:0051787	misfolded protein binding(GO:0051787)
1.6	6.5	GO:0000829	inositol heptakisphosphate kinase activity(GO:0000829)
1.6	8.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
1.6	4.7	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
1.6	4.7	GO:0042296	ISG15 transferase activity(GO:0042296)
1.5	6.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
1.5	21.2	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
1.5	6.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
1.5	8.9	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
1.5	4.4	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.4	5.7	GO:0005136	interleukin-4 receptor binding(GO:0005136)
1.4	5.7	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.4	11.4	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
1.4	4.3	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
1.4	11.2	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
1.4	6.8	GO:0015220	choline transmembrane transporter activity(GO:0015220)
1.4	6.8	GO:0043559	insulin binding(GO:0043559)
1.4	29.9	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
1.3	6.5	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.2	20.7	GO:0008395	steroid hydroxylase activity(GO:0008395)
1.2	4.8	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
1.2	3.6	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.2	4.8	GO:0030350	iron-responsive element binding(GO:0030350)
1.1	16.9	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
1.1	4.4	GO:0017089	glycolipid transporter activity(GO:0017089)
1.0	3.9	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
1.0	3.8	GO:0004452	isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.9	10.3	GO:0070324	thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)
0.9	3.7	GO:0050682	AF-2 domain binding(GO:0050682)
0.9	2.7	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
0.9	3.6	GO:0055100	adiponectin binding(GO:0055100)
0.9	8.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.9	14.8	GO:0001594	trace-amine receptor activity(GO:0001594)
0.9	8.7	GO:0005132	type I interferon receptor binding(GO:0005132)
0.9	18.9	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.8	6.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.8	197.2	GO:0017171	serine hydrolase activity(GO:0017171)
0.8	4.1	GO:1990254	keratin filament binding(GO:1990254)
0.8	27.8	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.8	3.3	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.8	7.3	GO:0017127	cholesterol transporter activity(GO:0017127)
0.8	8.0	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.8	4.7	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.8	7.0	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.8	3.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.8	8.4	GO:0005000	vasopressin receptor activity(GO:0005000)
0.8	3.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.7	11.0	GO:0034185	apolipoprotein binding(GO:0034185)
0.7	14.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.7	3.5	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.7	8.5	GO:0070403	NAD+ binding(GO:0070403)
0.7	31.6	GO:0001786	phosphatidylserine binding(GO:0001786)
0.7	9.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.6	1.9	GO:0019809	spermidine binding(GO:0019809)
0.6	2.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.6	5.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.6	54.9	GO:0005496	steroid binding(GO:0005496)
0.6	21.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.6	2.5	GO:0032190	acrosin binding(GO:0032190)
0.6	9.8	GO:0042166	acetylcholine binding(GO:0042166)
0.6	4.0	GO:0004064	arylesterase activity(GO:0004064)
0.6	5.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.5	14.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.5	7.7	GO:0033038	bitter taste receptor activity(GO:0033038)
0.5	1.6	GO:0000991	transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.5	3.6	GO:0031433	telethonin binding(GO:0031433)
0.5	1.5	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.5	2.5	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.5	5.0	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.5	2.4	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5	1.4	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.5	9.7	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.5	3.7	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.5	5.5	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.4	1.8	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.4	3.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.4	20.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.4	9.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.4	2.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.4	8.9	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.4	1.2	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.4	3.4	GO:0016805	dipeptidase activity(GO:0016805)
0.4	8.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.4	8.3	GO:0043274	phospholipase binding(GO:0043274)
0.3	3.5	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3	1.0	GO:0034618	arginine binding(GO:0034618)
0.3	3.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.3	2.7	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.3	13.6	GO:0030544	Hsp70 protein binding(GO:0030544)
0.3	1.6	GO:0005131	growth hormone receptor binding(GO:0005131)
0.3	2.2	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3	6.0	GO:0008266	poly(U) RNA binding(GO:0008266)
0.3	1.2	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.3	1.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.3	3.2	GO:0008097	5S rRNA binding(GO:0008097)
0.3	1.6	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.3	2.4	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.3	1.0	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.2	14.8	GO:0051087	chaperone binding(GO:0051087)
0.2	4.5	GO:0008199	ferric iron binding(GO:0008199)
0.2	4.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.2	4.9	GO:0008483	transaminase activity(GO:0008483)
0.2	3.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.2	2.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	1.3	GO:0034452	dynactin binding(GO:0034452)
0.2	0.8	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.2	4.8	GO:0031489	myosin V binding(GO:0031489)
0.2	3.5	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.2	4.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2	8.2	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2	255.5	GO:0004984	olfactory receptor activity(GO:0004984)
0.2	5.0	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	0.9	GO:0001729	ceramide kinase activity(GO:0001729)
0.2	16.4	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.2	21.3	GO:0001948	glycoprotein binding(GO:0001948)
0.2	8.8	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.2	0.5	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.2	16.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.2	4.0	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2	5.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	16.4	GO:0008565	protein transporter activity(GO:0008565)
0.2	3.4	GO:0005504	fatty acid binding(GO:0005504)
0.1	3.1	GO:0008198	ferrous iron binding(GO:0008198)
0.1	1.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	6.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	18.7	GO:0005179	hormone activity(GO:0005179)
0.1	1.7	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.6	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	3.0	GO:0003785	actin monomer binding(GO:0003785)
0.1	1.7	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	1.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	3.6	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	4.8	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.1	3.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	2.6	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	2.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.8	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.6	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.8	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	4.4	GO:0051018	protein kinase A binding(GO:0051018)
0.1	7.7	GO:0008083	growth factor activity(GO:0008083)
0.1	0.4	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1	0.9	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.3	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.6	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	2.5	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.3	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.6	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	2.6	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.0	0.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.6	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	1.6	GO:0005178	integrin binding(GO:0005178)
0.0	1.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.3	GO:0070001	aspartic-type peptidase activity(GO:0070001)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	70.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.9	20.7	ST JAK STAT PATHWAY	Jak-STAT Pathway
1.4	343.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.8	15.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.7	37.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.6	10.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.6	27.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.5	4.6	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.5	5.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.4	7.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.3	8.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.3	7.7	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3	49.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	14.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.3	10.3	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	14.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.3	13.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	10.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	9.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	15.9	PID P73PATHWAY	p73 transcription factor network
0.2	5.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	12.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.2	4.8	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2	10.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	2.9	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	1.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	7.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.7	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	3.5	PID ATM PATHWAY	ATM pathway
0.1	2.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.4	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.1	148.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
5.1	97.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
4.6	97.6	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
4.6	160.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
4.2	37.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
2.5	66.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.5	32.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
2.1	49.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
1.8	17.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
1.6	53.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
1.6	27.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.5	21.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
1.5	8.9	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
1.5	11.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.5	26.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
1.4	24.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.4	6.8	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.3	8.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
1.3	22.8	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.2	35.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
1.0	11.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.0	20.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.9	151.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.9	12.2	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.8	9.8	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8	71.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.8	32.9	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.7	57.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.7	12.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.7	10.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.7	12.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7	6.0	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.6	14.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.6	11.4	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.5	10.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.5	8.8	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.5	26.4	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.5	6.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.5	14.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.5	25.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.4	8.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4	8.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.4	6.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.4	6.1	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.4	1.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.4	26.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.3	3.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	6.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.3	6.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.3	12.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	5.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3	3.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.3	6.6	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.2	4.0	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	2.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.2	6.8	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2	5.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.2	6.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	3.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.2	4.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.2	5.5	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.2	10.7	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.1	3.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	5.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	3.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	2.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	0.8	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	1.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	2.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	1.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	4.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	1.0	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	2.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.0	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	4.2	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	2.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.0	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis

Results for Cux1

Z-value: 1.76

Motif logo

Transcription factors associated with Cux1

Activity-expression correlation:

Activity profile of Cux1 motif

Sorted Z-values of Cux1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Cux1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: