ISMARA results: Dlx5

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Dlx5_Dlx4

Z-value: 0.70

Motif logo

Transcription factors associated with Dlx5_Dlx4

Gene Symbol	Gene ID	Gene Info
Dlx5 NCBI RGD Ensembl	ENSRNOG00000010905	distal-less homeobox 5
Dlx4 NCBI RGD Ensembl	ENSRNOG00000004399	distal-less homeobox 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Dlx4	rn6_v1_chr10_-_82963919_82963919	-0.35	1.5e-10	Click!
Dlx5	rn6_v1_chr4_-_32392007_32392007	-0.29	8.6e-08	Click!

Activity profile of Dlx5_Dlx4 motif

Sorted Z-values of Dlx5_Dlx4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_+_22375955 Show fit	29.58	ENSRNOT00000063915 ENSRNOT00000034784	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr2_-_216382244 Show fit	27.33	ENSRNOT00000086695 ENSRNOT00000087259	LOC103689940 NCBI RGD Ensembl Show fit	pancreatic alpha-amylase-like
chr17_+_72160735 Show fit	26.79	ENSRNOT00000038817	Itih2 NCBI RGD Ensembl Show fit	inter-alpha-trypsin inhibitor heavy chain 2
chr2_-_216348194 Show fit	20.13	ENSRNOT00000087839	LOC103689940 NCBI RGD Ensembl Show fit	pancreatic alpha-amylase-like
chr17_+_9736786 Show fit	17.02	ENSRNOT00000081920	F12 NCBI RGD Ensembl Show fit	coagulation factor XII
chr1_+_140998240 Show fit	16.73	ENSRNOT00000023506 ENSRNOT00000090897	Abhd2 NCBI RGD Ensembl Show fit	abhydrolase domain containing 2
chr10_+_96639924 Show fit	16.42	ENSRNOT00000004756	Apoh NCBI RGD Ensembl Show fit	apolipoprotein H
chr13_-_47397890 Show fit	16.27	ENSRNOT00000005505	C4bpb NCBI RGD Ensembl Show fit	complement component 4 binding protein, beta
chr6_+_2216623 Show fit	14.48	ENSRNOT00000008045	Rmdn2 NCBI RGD Ensembl Show fit	regulator of microtubule dynamics 2
chr1_-_148119857 Show fit	14.16	ENSRNOT00000040325	LOC100361547 NCBI RGD Ensembl Show fit	Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr14_+_22517774 Show fit	13.97	ENSRNOT00000047655	Ugt2b37 NCBI RGD Ensembl Show fit	UDP-glucuronosyltransferase 2 family, member 37
chr1_+_248428099 Show fit	13.70	ENSRNOT00000050984	Mbl2 NCBI RGD Ensembl Show fit	mannose binding lectin 2
chr2_+_54466280 Show fit	13.30	ENSRNOT00000033112	C6 NCBI RGD Ensembl Show fit	complement C6
chr6_+_127946686 Show fit	13.12	ENSRNOT00000082680	LOC500712 NCBI RGD Ensembl Show fit	Ab1-233
chr17_+_76008807 Show fit	12.97	ENSRNOT00000070895	Echdc3 NCBI RGD Ensembl Show fit	enoyl CoA hydratase domain containing 3
chr4_+_154676427 Show fit	12.48	ENSRNOT00000019969 ENSRNOT00000087441	Mug1 NCBI RGD Ensembl Show fit	murinoglobulin 1
chr5_+_117698764 Show fit	11.96	ENSRNOT00000011486	Angptl3 NCBI RGD Ensembl Show fit	angiopoietin-like 3
chr1_+_279896973 Show fit	11.74	ENSRNOT00000068119	Pnliprp2 NCBI RGD Ensembl Show fit	pancreatic lipase related protein 2
chr2_+_200793571 Show fit	11.04	ENSRNOT00000091444	Hao2 NCBI RGD Ensembl Show fit	hydroxyacid oxidase 2
chr12_+_10636275 Show fit	10.68	ENSRNOT00000001285	Cyp3a18 NCBI RGD Ensembl Show fit	cytochrome P450, family 3, subfamily a, polypeptide 18
chr14_+_5928737 Show fit	10.06	ENSRNOT00000071877 ENSRNOT00000040985 ENSRNOT00000074889	Mpa2l NCBI RGD Ensembl Show fit	macrophage activation 2 like
chr3_-_14229067 Show fit	10.02	ENSRNOT00000025534 ENSRNOT00000092865	C5 NCBI RGD Ensembl Show fit	complement C5
chr9_-_27447877 Show fit	10.02	ENSRNOT00000085195	Gsta1 NCBI RGD Ensembl Show fit	glutathione S-transferase alpha 1
chr12_-_19167015 Show fit	9.99	ENSRNOT00000001797	Gjc3 NCBI RGD Ensembl Show fit	gap junction protein, gamma 3
chrM_+_7758 Show fit	9.96	ENSRNOT00000046201	Mt-atp8 NCBI RGD Ensembl Show fit	mitochondrially encoded ATP synthase 8
chr6_-_128003418 Show fit	9.94	ENSRNOT00000013896	Serpina3c NCBI RGD Ensembl Show fit	serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr9_+_100281339 Show fit	9.31	ENSRNOT00000029127	Agxt NCBI RGD Ensembl Show fit	alanine-glyoxylate aminotransferase
chr13_+_78812394 Show fit	9.30	ENSRNOT00000076043	Serpinc1 NCBI RGD Ensembl Show fit	serpin family C member 1
chr15_+_57290849 Show fit	9.18	ENSRNOT00000014909	Cpb2 NCBI RGD Ensembl Show fit	carboxypeptidase B2
chr3_+_54253949 Show fit	9.10	ENSRNOT00000010018	B3galt1 NCBI RGD Ensembl Show fit	Beta-1,3-galactosyltransferase 1
chr11_+_74057361 Show fit	9.10	ENSRNOT00000048746	Cpn2 NCBI RGD Ensembl Show fit	carboxypeptidase N subunit 2
chr20_+_13817795 Show fit	9.05	ENSRNOT00000036518	Gstt3 NCBI RGD Ensembl Show fit	glutathione S-transferase, theta 3
chr1_-_198104109 Show fit	8.85	ENSRNOT00000026186	Sult1a1 NCBI RGD Ensembl Show fit	sulfotransferase family 1A member 1
chr10_-_98544447 Show fit	8.80	ENSRNOT00000073149	Abca6 NCBI RGD Ensembl Show fit	ATP binding cassette subfamily A member 6
chr17_-_43537293 Show fit	8.79	ENSRNOT00000091749	Slc17a3 NCBI RGD Ensembl Show fit	solute carrier family 17 member 3
chr2_+_55775274 Show fit	8.71	ENSRNOT00000018545	C9 NCBI RGD Ensembl Show fit	complement C9
chr14_-_21748356 Show fit	8.64	ENSRNOT00000002670	Cabs1 NCBI RGD Ensembl Show fit	calcium binding protein, spermatid associated 1
chr2_-_182038178 Show fit	8.25	ENSRNOT00000040708	Fgb NCBI RGD Ensembl Show fit	fibrinogen beta chain
chr10_+_56662561 Show fit	8.13	ENSRNOT00000025254	Asgr1 NCBI RGD Ensembl Show fit	asialoglycoprotein receptor 1
chr9_-_80295446 Show fit	7.79	ENSRNOT00000023769	Tnp1 NCBI RGD Ensembl Show fit	transition protein 1
chr6_-_127816055 Show fit	7.75	ENSRNOT00000013175	Serpina3m NCBI RGD Ensembl Show fit	serine (or cysteine) proteinase inhibitor, clade A, member 3M
chr10_+_56662242 Show fit	7.72	ENSRNOT00000086919	Asgr1 NCBI RGD Ensembl Show fit	asialoglycoprotein receptor 1
chr12_+_19196611 Show fit	7.67	ENSRNOT00000001801	Azgp1 NCBI RGD Ensembl Show fit	alpha-2-glycoprotein 1, zinc-binding
chr1_-_258877045 Show fit	7.47	ENSRNOT00000071633	Cyp2c13 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 13
chr17_-_69711689 Show fit	7.40	ENSRNOT00000041925	Akr1c12 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C12
chr16_+_74865516 Show fit	7.39	ENSRNOT00000058072	Atp7b NCBI RGD Ensembl Show fit	ATPase copper transporting beta
chr14_+_96499520 Show fit	7.38	ENSRNOT00000074692	AABR07016310.1 NCBI RGD Ensembl Show fit
chr9_-_4945352 Show fit	7.32	ENSRNOT00000082530	Sult1c3 NCBI RGD Ensembl Show fit	sulfotransferase family 1C member 3
chr3_+_16571602 Show fit	7.28	ENSRNOT00000048351	LOC100361705 NCBI RGD Ensembl Show fit	rCG64259-like
chr4_+_148782479 Show fit	7.12	ENSRNOT00000018133	LOC500300 NCBI RGD Ensembl Show fit	similar to hypothetical protein MGC6835
chr9_+_95161157 Show fit	7.00	ENSRNOT00000071200	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr1_+_213511874 Show fit	6.94	ENSRNOT00000078080 ENSRNOT00000016883	Cyp2e1 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily e, polypeptide 1
chr15_-_42693694 Show fit	6.86	ENSRNOT00000022702	Gulo NCBI RGD Ensembl Show fit	gulonolactone (L-) oxidase
chr14_+_22142364 Show fit	6.78	ENSRNOT00000002699	Sult1b1 NCBI RGD Ensembl Show fit	sulfotransferase family 1B member 1
chr11_-_81444375 Show fit	6.74	ENSRNOT00000058479 ENSRNOT00000078131 ENSRNOT00000080949 ENSRNOT00000080562 ENSRNOT00000084867	Kng1 NCBI RGD Ensembl Show fit	kininogen 1
chr8_+_62779875 Show fit	6.68	ENSRNOT00000010831	Cyp11a1 NCBI RGD Ensembl Show fit	cytochrome P450, family 11, subfamily a, polypeptide 1
chr3_+_19366370 Show fit	6.60	ENSRNOT00000086557	AABR07051689.1 NCBI RGD Ensembl Show fit
chr1_-_164142206 Show fit	6.58	ENSRNOT00000081669	Dgat2 NCBI RGD Ensembl Show fit	diacylglycerol O-acyltransferase 2
chr2_+_223121410 Show fit	6.56	ENSRNOT00000087559	AABR07013116.1 NCBI RGD Ensembl Show fit
chr20_-_12820466 Show fit	6.42	ENSRNOT00000001699	Ftcd NCBI RGD Ensembl Show fit	formimidoyltransferase cyclodeaminase
chr11_-_87924816 Show fit	6.37	ENSRNOT00000031819	Serpind1 NCBI RGD Ensembl Show fit	serpin family D member 1
chr12_+_18679789 Show fit	6.33	ENSRNOT00000001863	Cyp3a9 NCBI RGD Ensembl Show fit	cytochrome P450, family 3, subfamily a, polypeptide 9
chr7_+_34326087 Show fit	6.30	ENSRNOT00000006971	Hal NCBI RGD Ensembl Show fit	histidine ammonia lyase
chr1_+_55219773 Show fit	6.02	ENSRNOT00000041610	RGD1561667 NCBI RGD Ensembl Show fit	similar to putative protein kinase
chr16_-_74864816 Show fit	6.01	ENSRNOT00000017164	Alg11 NCBI RGD Ensembl Show fit	ALG11, alpha-1,2-mannosyltransferase
chr3_+_18970574 Show fit	5.98	ENSRNOT00000088394	AABR07051665.1 NCBI RGD Ensembl Show fit
chr1_-_258766881 Show fit	5.94	ENSRNOT00000015801	Cyp2c12 NCBI RGD Ensembl Show fit	cytochrome P450, family 2, subfamily c, polypeptide 12
chr4_+_98481520 Show fit	5.91	ENSRNOT00000078381 ENSRNOT00000048493	AABR07060886.1 NCBI RGD Ensembl Show fit
chr10_+_109665682 Show fit	5.90	ENSRNOT00000054963	Slc25a10 NCBI RGD Ensembl Show fit	solute carrier family 25 member 10
chr14_-_5859581 Show fit	5.80	ENSRNOT00000052308	AABR07014241.1 NCBI RGD Ensembl Show fit
chr1_+_282567674 Show fit	5.77	ENSRNOT00000090543	Ces2i NCBI RGD Ensembl Show fit	carboxylesterase 2I
chr16_-_24951612 Show fit	5.66	ENSRNOT00000018987	Tktl2 NCBI RGD Ensembl Show fit	transketolase-like 2
chr6_+_139405966 Show fit	5.49	ENSRNOT00000088974	AABR07065693.3 NCBI RGD Ensembl Show fit
chr9_+_61692154 Show fit	5.49	ENSRNOT00000082300	Hspe1 NCBI RGD Ensembl Show fit	heat shock protein family E member 1
chr15_+_28319136 Show fit	5.44	ENSRNOT00000048723	Tppp2 NCBI RGD Ensembl Show fit	tubulin polymerization-promoting protein family member 2
chr4_-_117575154 Show fit	5.32	ENSRNOT00000075813	LOC102556148 NCBI RGD Ensembl Show fit	probable N-acetyltransferase CML2-like
chr9_-_114327767 Show fit	5.29	ENSRNOT00000085481	AABR07068674.1 NCBI RGD Ensembl Show fit
chr3_-_15278645 Show fit	5.23	ENSRNOT00000032204	Ttll11 NCBI RGD Ensembl Show fit	tubulin tyrosine ligase like11
chr3_+_18315320 Show fit	5.21	ENSRNOT00000006954	AABR07051626.2 NCBI RGD Ensembl Show fit
chr14_-_79464770 Show fit	5.12	ENSRNOT00000008932	Grpel1 NCBI RGD Ensembl Show fit	GrpE-like 1, mitochondrial
chr2_+_140708397 Show fit	5.08	ENSRNOT00000088846	Mgst2 NCBI RGD Ensembl Show fit	microsomal glutathione S-transferase 2
chr16_+_50152008 Show fit	5.03	ENSRNOT00000019237	Klkb1 NCBI RGD Ensembl Show fit	kallikrein B1
chr1_-_227457629 Show fit	4.95	ENSRNOT00000035910 ENSRNOT00000073770	Ms4a5 NCBI RGD Ensembl Show fit	membrane spanning 4-domains A5
chr4_-_30338679 Show fit	4.88	ENSRNOT00000012050	Pon3 NCBI RGD Ensembl Show fit	paraoxonase 3
chr10_-_87286387 Show fit	4.86	ENSRNOT00000044206	Krt28 NCBI RGD Ensembl Show fit	keratin 28
chr15_+_28018040 Show fit	4.79	ENSRNOT00000041495	Rnase4 NCBI RGD Ensembl Show fit	ribonuclease A family member 4
chr3_+_16846412 Show fit	4.79	ENSRNOT00000074266	AABR07051551.1 NCBI RGD Ensembl Show fit
chr11_+_88095170 Show fit	4.73	ENSRNOT00000041557	Ccdc116 NCBI RGD Ensembl Show fit	coiled-coil domain containing 116
chr17_-_69404323 Show fit	4.68	ENSRNOT00000051342 ENSRNOT00000066282	Akr1c2 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C2
chr4_+_117962319 Show fit	4.64	ENSRNOT00000057441	Tgfa NCBI RGD Ensembl Show fit	transforming growth factor alpha
chr3_+_159936856 Show fit	4.61	ENSRNOT00000078703	Hnf4a NCBI RGD Ensembl Show fit	hepatocyte nuclear factor 4, alpha
chr9_+_95501778 Show fit	4.56	ENSRNOT00000086805	Spp2 NCBI RGD Ensembl Show fit	secreted phosphoprotein 2
chr2_-_105089659 Show fit	4.54	ENSRNOT00000043381	Cpb1 NCBI RGD Ensembl Show fit	carboxypeptidase B1
chr2_+_93758919 Show fit	4.51	ENSRNOT00000077782	Fabp12 NCBI RGD Ensembl Show fit	fatty acid binding protein 12
chr6_-_41870046 Show fit	4.46	ENSRNOT00000005863	Lpin1 NCBI RGD Ensembl Show fit	lipin 1
chr8_-_115274165 Show fit	4.45	ENSRNOT00000056386	LOC102550160 NCBI RGD Ensembl Show fit	IQ domain-containing protein F5-like
chr3_+_19045214 Show fit	4.45	ENSRNOT00000070878	AABR07051670.1 NCBI RGD Ensembl Show fit
chr1_+_229030233 Show fit	4.44	ENSRNOT00000084503	Glyatl1 NCBI RGD Ensembl Show fit	glycine-N-acyltransferase-like 1
chr17_-_43584152 Show fit	4.42	ENSRNOT00000023241	Slc17a2 NCBI RGD Ensembl Show fit	solute carrier family 17, member 2
chr1_-_275882444 Show fit	4.38	ENSRNOT00000083215	Gpam NCBI RGD Ensembl Show fit	glycerol-3-phosphate acyltransferase, mitochondrial
chr16_+_68586235 Show fit	4.38	ENSRNOT00000039592	LOC103693984 NCBI RGD Ensembl Show fit	uncharacterized LOC103693984
chr17_-_42127678 Show fit	4.35	ENSRNOT00000024196	Gpld1 NCBI RGD Ensembl Show fit	glycosylphosphatidylinositol specific phospholipase D1
chr2_+_154921999 Show fit	4.27	ENSRNOT00000057620	LOC691044 NCBI RGD Ensembl Show fit	similar to GTPase activating protein testicular GAP1
chr2_+_243502073 Show fit	4.26	ENSRNOT00000015870	Adh7 NCBI RGD Ensembl Show fit	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_-_37450340 Show fit	4.26	ENSRNOT00000072224	LOC100912405 NCBI RGD Ensembl Show fit	urinary protein 3-like
chr15_+_18710492 Show fit	4.24	ENSRNOT00000012532	Dnase1l3 NCBI RGD Ensembl Show fit	deoxyribonuclease 1-like 3
chr6_-_128149220 Show fit	4.24	ENSRNOT00000014204	Gsc NCBI RGD Ensembl Show fit	goosecoid homeobox
chr2_+_26240385 Show fit	4.12	ENSRNOT00000024292	F2rl2 NCBI RGD Ensembl Show fit	coagulation factor II (thrombin) receptor-like 2
chr7_+_23012070 Show fit	4.08	ENSRNOT00000042460	LOC300308 NCBI RGD Ensembl Show fit	similar to hypothetical protein 4930509O22
chr14_-_2032593 Show fit	4.08	ENSRNOT00000000037	Fgfrl1 NCBI RGD Ensembl Show fit	fibroblast growth factor receptor-like 1
chr8_+_85059051 Show fit	4.00	ENSRNOT00000033196	Gclc NCBI RGD Ensembl Show fit	glutamate-cysteine ligase, catalytic subunit
chr2_+_150146234 Show fit	3.99	ENSRNOT00000018761	Aadac NCBI RGD Ensembl Show fit	arylacetamide deacetylase
chr7_+_20262680 Show fit	3.97	ENSRNOT00000046378	LOC300308 NCBI RGD Ensembl Show fit	similar to hypothetical protein 4930509O22
chr2_+_60131776 Show fit	3.95	ENSRNOT00000080786	Prlr NCBI RGD Ensembl Show fit	prolactin receptor
chr8_-_8524643 Show fit	3.93	ENSRNOT00000009418	Cntn5 NCBI RGD Ensembl Show fit	contactin 5
chr9_-_79630452 Show fit	3.90	ENSRNOT00000078125 ENSRNOT00000086044 ENSRNOT00000089283	Pecr NCBI RGD Ensembl Show fit	peroxisomal trans-2-enoyl-CoA reductase
chr7_+_16404755 Show fit	3.89	ENSRNOT00000044977	LOC108349290 NCBI RGD Ensembl Show fit	olfactory receptor 6C70-like
chr9_-_98551410 Show fit	3.82	ENSRNOT00000066346 ENSRNOT00000086678	Hes6 NCBI RGD Ensembl Show fit	hes family bHLH transcription factor 6
chr19_+_52258947 Show fit	3.76	ENSRNOT00000021072	Adad2 NCBI RGD Ensembl Show fit	adenosine deaminase domain containing 2
chrX_+_45965301 Show fit	3.75	ENSRNOT00000005141	Fam47a NCBI RGD Ensembl Show fit	family with sequence similarity 47, member A
chr1_+_22332090 Show fit	3.73	ENSRNOT00000091252	AABR07000663.1 NCBI RGD Ensembl Show fit	trace amine-associated receptor 8c (Taar8c), mRNA
chr3_-_26056818 Show fit	3.72	ENSRNOT00000044209	Lrp1b NCBI RGD Ensembl Show fit	LDL receptor related protein 1B
chr4_-_176528110 Show fit	3.72	ENSRNOT00000049569	Slco1a2 NCBI RGD Ensembl Show fit	solute carrier organic anion transporter family, member 1A2
chr2_+_200397967 Show fit	3.66	ENSRNOT00000025821	Reg4 NCBI RGD Ensembl Show fit	regenerating family member 4
chr4_+_1658278 Show fit	3.63	ENSRNOT00000073845	Olr1250 NCBI RGD Ensembl Show fit	olfactory receptor 1250
chr8_-_56393233 Show fit	3.61	ENSRNOT00000016263	Fdx1 NCBI RGD Ensembl Show fit	ferredoxin 1
chr6_+_10483308 Show fit	3.57	ENSRNOT00000074516	Tmem247 NCBI RGD Ensembl Show fit	transmembrane protein 247
chr3_+_18805220 Show fit	3.54	ENSRNOT00000071216	Igkv4-86 NCBI RGD Ensembl Show fit	immunoglobulin kappa variable 4-86
chr6_-_138852571 Show fit	3.53	ENSRNOT00000081803	AABR07065656.8 NCBI RGD Ensembl Show fit
chr19_+_15081590 Show fit	3.53	ENSRNOT00000024187	Ces1f NCBI RGD Ensembl Show fit	carboxylesterase 1F
chrX_-_23139694 Show fit	3.50	ENSRNOT00000033656	Pfkfb1 NCBI RGD Ensembl Show fit	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr4_-_155051429 Show fit	3.49	ENSRNOT00000020094	Klrg1 NCBI RGD Ensembl Show fit	killer cell lectin like receptor G1
chr1_+_264260505 Show fit	3.48	ENSRNOT00000018815	Wnt8b NCBI RGD Ensembl Show fit	wingless-type MMTV integration site family, member 8B
chr6_-_115616766 Show fit	3.47	ENSRNOT00000006143 ENSRNOT00000045870	Sel1l NCBI RGD Ensembl Show fit	SEL1L ERAD E3 ligase adaptor subunit
chr5_-_12526962 Show fit	3.43	ENSRNOT00000092104	St18 NCBI RGD Ensembl Show fit	suppression of tumorigenicity 18
chr3_-_16999720 Show fit	3.42	ENSRNOT00000074382	RGD1563231 NCBI RGD Ensembl Show fit	similar to immunoglobulin kappa-chain VK-1
chr9_-_105655471 Show fit	3.37	ENSRNOT00000014921	RGD1560925 NCBI RGD Ensembl Show fit	similar to 2610034M16Rik protein
chr8_+_57983556 Show fit	3.37	ENSRNOT00000009562	RGD1311251 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 4930550C14
chr16_+_72139063 Show fit	3.33	ENSRNOT00000023805	Adam18 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 18
chr15_-_10455956 Show fit	3.33	ENSRNOT00000008289	Ngly1 NCBI RGD Ensembl Show fit	N-glycanase 1
chr1_+_167937026 Show fit	3.31	ENSRNOT00000020655	Olr57 NCBI RGD Ensembl Show fit	olfactory receptor 57
chr6_+_64789940 Show fit	3.31	ENSRNOT00000085979 ENSRNOT00000059739 ENSRNOT00000051908 ENSRNOT00000082793 ENSRNOT00000078583 ENSRNOT00000091677 ENSRNOT00000093241	Nrcam NCBI RGD Ensembl Show fit	neuronal cell adhesion molecule
chr1_-_81596819 Show fit	3.30	ENSRNOT00000074350	RGD1564380 NCBI RGD Ensembl Show fit	similar to BC049730 protein
chr6_-_92643847 Show fit	3.26	ENSRNOT00000009183	Pygl NCBI RGD Ensembl Show fit	glycogen phosphorylase L
chr4_-_163095614 Show fit	3.25	ENSRNOT00000088759	RGD1564770 NCBI RGD Ensembl Show fit	similar to CD69 antigen (p60, early T-cell activation antigen)
chr1_+_31409579 Show fit	3.22	ENSRNOT00000016989	RGD1311933 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA 2310057J18
chr6_-_7058314 Show fit	3.21	ENSRNOT00000045996	Haao NCBI RGD Ensembl Show fit	3-hydroxyanthranilate 3,4-dioxygenase
chr9_-_85243001 Show fit	3.20	ENSRNOT00000020219	Scg2 NCBI RGD Ensembl Show fit	secretogranin II
chr17_+_69588085 Show fit	3.19	ENSRNOT00000064884	Akr1c12l1 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C12-like 1
chr6_-_139033819 Show fit	3.19	ENSRNOT00000091961	AABR07065656.6 NCBI RGD Ensembl Show fit
chr3_-_20419417 Show fit	3.18	ENSRNOT00000077772	AABR07051733.3 NCBI RGD Ensembl Show fit
chr11_+_85532526 Show fit	3.17	ENSRNOT00000036565	AABR07034730.2 NCBI RGD Ensembl Show fit
chr8_+_112594691 Show fit	3.16	ENSRNOT00000038383 ENSRNOT00000081281	Acad11 NCBI RGD Ensembl Show fit	acyl-CoA dehydrogenase family, member 11
chr8_-_54994871 Show fit	3.15	ENSRNOT00000013014	Tex12 NCBI RGD Ensembl Show fit	testis expressed 12
chr13_-_57080491 Show fit	3.14	ENSRNOT00000017749 ENSRNOT00000086572 ENSRNOT00000060111	Cfh NCBI RGD Ensembl Show fit	complement factor H
chr6_-_139911839 Show fit	3.11	ENSRNOT00000077113 ENSRNOT00000084547	AABR07065714.1 NCBI RGD Ensembl Show fit
chrM_+_10160 Show fit	3.11	ENSRNOT00000042928	Mt-nd4 NCBI RGD Ensembl Show fit	mitochondrially encoded NADH dehydrogenase 4
chr5_-_77749613 Show fit	3.08	ENSRNOT00000075988	Mup5 NCBI RGD Ensembl Show fit	major urinary protein 5
chr3_-_19320915 Show fit	3.08	ENSRNOT00000043673	RGD1565617 NCBI RGD Ensembl Show fit	similar to Ig variable region, light chain
chr5_-_136965191 Show fit	3.08	ENSRNOT00000056842	St3gal3 NCBI RGD Ensembl Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr16_-_49820235 Show fit	3.07	ENSRNOT00000029628	Sorbs2 NCBI RGD Ensembl Show fit	sorbin and SH3 domain containing 2
chr15_+_28028521 Show fit	3.04	ENSRNOT00000089631	AC114343.1 NCBI RGD Ensembl Show fit
chr17_+_69634890 Show fit	3.04	ENSRNOT00000029049	Akr1c13 NCBI RGD Ensembl Show fit	aldo-keto reductase family 1, member C13
chr1_+_276240703 Show fit	3.03	ENSRNOT00000022126	Acsl5 NCBI RGD Ensembl Show fit	acyl-CoA synthetase long-chain family member 5
chr4_+_70689737 Show fit	3.03	ENSRNOT00000018852	Prss2 NCBI RGD Ensembl Show fit	protease, serine, 2
chrX_+_78769419 Show fit	3.02	ENSRNOT00000003190	Tbx22 NCBI RGD Ensembl Show fit	T-box 22
chr7_-_129970550 Show fit	3.02	ENSRNOT00000055879	Mlc1 NCBI RGD Ensembl Show fit	megalencephalic leukoencephalopathy with subcortical cysts 1
chr13_+_75177965 Show fit	2.98	ENSRNOT00000007321	Sec16b NCBI RGD Ensembl Show fit	SEC16 homolog B, endoplasmic reticulum export factor
chr4_+_70977556 Show fit	2.97	ENSRNOT00000031984	LOC680112 NCBI RGD Ensembl Show fit	hypothetical protein LOC680112
chr1_+_219833299 Show fit	2.97	ENSRNOT00000087432	Pc NCBI RGD Ensembl Show fit	pyruvate carboxylase
chr6_+_78567970 Show fit	2.96	ENSRNOT00000032743	Ttc6 NCBI RGD Ensembl Show fit	tetratricopeptide repeat domain 6
chr1_+_64506735 Show fit	2.96	ENSRNOT00000086331	Nlrp12 NCBI RGD Ensembl Show fit	NLR family, pyrin domain containing 12
chr7_+_44009069 Show fit	2.95	ENSRNOT00000005523	Mgat4c NCBI RGD Ensembl Show fit	MGAT4 family, member C
chr20_-_30947484 Show fit	2.94	ENSRNOT00000065614	Pald1 NCBI RGD Ensembl Show fit	phosphatase domain containing, paladin 1
chr6_-_140880070 Show fit	2.93	ENSRNOT00000073779	LOC691828 NCBI RGD Ensembl Show fit	uncharacterized LOC691828
chr3_-_16441030 Show fit	2.92	ENSRNOT00000047784	AABR07051532.1 NCBI RGD Ensembl Show fit
chr1_+_102924059 Show fit	2.92	ENSRNOT00000078137	AC099150.1 NCBI RGD Ensembl Show fit
chr1_+_201913148 Show fit	2.90	ENSRNOT00000036128	Fam24a NCBI RGD Ensembl Show fit	family with sequence similarity 24, member A
chr6_-_143590448 Show fit	2.87	ENSRNOT00000056771	Ighv8-4 NCBI RGD Ensembl Show fit	immunoglobulin heavy variable V8-4
chr3_-_66417741 Show fit	2.85	ENSRNOT00000007662	Neurod1 NCBI RGD Ensembl Show fit	neuronal differentiation 1
chr15_+_33885106 Show fit	2.83	ENSRNOT00000024483	Dhrs2 NCBI RGD Ensembl Show fit	dehydrogenase/reductase 2
chr4_-_151428894 Show fit	2.82	ENSRNOT00000010556	Adipor2 NCBI RGD Ensembl Show fit	adiponectin receptor 2
chr20_+_31339787 Show fit	2.82	ENSRNOT00000082463	Aifm2 NCBI RGD Ensembl Show fit	apoptosis inducing factor, mitochondria associated 2
chr6_-_142372031 Show fit	2.81	ENSRNOT00000063929	AABR07065814.3 NCBI RGD Ensembl Show fit
chr17_+_15194262 Show fit	2.81	ENSRNOT00000073070	AABR07072539.1 NCBI RGD Ensembl Show fit
chr6_-_143065639 Show fit	2.80	ENSRNOT00000070923	AABR07065827.1 NCBI RGD Ensembl Show fit
chr1_+_222861777 Show fit	2.79	ENSRNOT00000090872	Pla2g16 NCBI RGD Ensembl Show fit	phospholipase A2, group XVI
chr20_+_1736377 Show fit	2.79	ENSRNOT00000047035	Olr1734 NCBI RGD Ensembl Show fit	olfactory receptor 1734
chr19_+_3325893 Show fit	2.77	ENSRNOT00000048879	RGD1565617 NCBI RGD Ensembl Show fit	similar to Ig variable region, light chain
chr10_+_1834518 Show fit	2.76	ENSRNOT00000061709	Gm1758 NCBI RGD Ensembl Show fit	predicted gene 1758
chr3_-_64543100 Show fit	2.69	ENSRNOT00000025803	Zfp385b NCBI RGD Ensembl Show fit	zinc finger protein 385B
chr2_-_132551235 Show fit	2.68	ENSRNOT00000058250	LOC100365525 NCBI RGD Ensembl Show fit	rCG65904-like
chr8_-_78233430 Show fit	2.68	ENSRNOT00000083220	Cgnl1 NCBI RGD Ensembl Show fit	cingulin-like 1
chr6_-_141866756 Show fit	2.65	ENSRNOT00000068561	AABR07065804.1 NCBI RGD Ensembl Show fit
chr4_+_102262007 Show fit	2.65	ENSRNOT00000079328	AABR07060992.2 NCBI RGD Ensembl Show fit
chr5_-_24926904 Show fit	2.64	ENSRNOT00000075288	AABR07047232.1 NCBI RGD Ensembl Show fit
chr2_-_24923128 Show fit	2.63	ENSRNOT00000044087	Pde8b NCBI RGD Ensembl Show fit	phosphodiesterase 8B
chr20_+_1749716 Show fit	2.61	ENSRNOT00000048856	Olr1735 NCBI RGD Ensembl Show fit	olfactory receptor 1735
chr10_-_87578854 Show fit	2.60	ENSRNOT00000065619	LOC680160 NCBI RGD Ensembl Show fit	similar to keratin associated protein 4-7
chr10_-_98124743 Show fit	2.59	ENSRNOT00000037415	RGD1559578 NCBI RGD Ensembl Show fit	RGD1559578

Network of associatons between targets according to the STRING database.

First level regulatory network of Dlx5_Dlx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.2	28.9	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
6.4	25.7	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
5.7	17.0	GO:0002254	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
5.4	16.3	GO:0045959	negative regulation of complement activation, classical pathway(GO:0045959)
4.2	12.7	GO:0015942	formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
3.7	11.0	GO:0018924	mandelate metabolic process(GO:0018924)
3.1	9.3	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate(GO:0019265) oxalic acid secretion(GO:0046724)
3.1	9.2	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.5	7.4	GO:0015680	intracellular copper ion transport(GO:0015680)
2.4	12.0	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
2.2	15.6	GO:0009812	flavonoid metabolic process(GO:0009812)
2.2	4.3	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
2.1	6.3	GO:0002933	lipid hydroxylation(GO:0002933)
2.1	18.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
2.0	5.9	GO:0071422	succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
1.8	12.4	GO:0019374	galactolipid metabolic process(GO:0019374)
1.7	6.9	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
1.6	8.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
1.6	4.7	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.4	6.9	GO:0016098	monoterpenoid metabolic process(GO:0016098)
1.4	14.9	GO:0042178	xenobiotic catabolic process(GO:0042178)
1.3	6.7	GO:0060014	granulosa cell differentiation(GO:0060014)
1.3	6.6	GO:0071400	cellular response to oleic acid(GO:0071400)
1.3	3.9	GO:0033306	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
1.3	1.3	GO:0034418	urate biosynthetic process(GO:0034418)
1.2	4.9	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.2	3.6	GO:0006574	valine catabolic process(GO:0006574)
1.2	4.6	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
1.2	10.4	GO:0052697	xenobiotic glucuronidation(GO:0052697)
1.1	27.3	GO:0019373	epoxygenase P450 pathway(GO:0019373)
1.0	7.2	GO:0007290	spermatid nucleus elongation(GO:0007290)
1.0	3.0	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
1.0	5.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
1.0	4.0	GO:0097069	cellular response to thyroxine stimulus(GO:0097069)
1.0	3.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588) regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
1.0	1.9	GO:0014016	neuroblast differentiation(GO:0014016)
0.8	3.4	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.8	3.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.8	25.6	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.8	2.3	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.8	3.9	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.7	2.2	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
0.7	4.5	GO:0006642	triglyceride mobilization(GO:0006642)
0.7	3.0	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.7	4.3	GO:0006069	ethanol oxidation(GO:0006069)
0.7	17.6	GO:0048240	sperm capacitation(GO:0048240)
0.7	9.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.6	1.9	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.6	1.9	GO:0018343	protein farnesylation(GO:0018343)
0.6	2.5	GO:0098705	copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.5	8.8	GO:0046415	urate metabolic process(GO:0046415)
0.5	2.2	GO:0035772	interleukin-13-mediated signaling pathway(GO:0035772)
0.5	2.6	GO:0035106	operant conditioning(GO:0035106)
0.5	5.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.5	1.6	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655)
0.5	3.5	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.5	3.0	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.5	4.4	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.5	4.9	GO:0070995	NADPH oxidation(GO:0070995)
0.5	4.4	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.5	1.4	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.5	5.7	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.5	2.8	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.5	1.4	GO:0019086	late viral transcription(GO:0019086)
0.5	1.4	GO:0060468	prevention of polyspermy(GO:0060468)
0.5	3.2	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.4	2.2	GO:0030070	insulin processing(GO:0030070)
0.4	4.0	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.4	2.2	GO:0031296	positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.4	3.9	GO:0038161	prolactin signaling pathway(GO:0038161)
0.4	1.3	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.4	8.7	GO:0035404	histone-serine phosphorylation(GO:0035404)
0.4	3.4	GO:0006776	vitamin A metabolic process(GO:0006776)
0.4	3.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.4	2.1	GO:0036233	glycine import(GO:0036233)
0.4	0.9	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
0.4	3.8	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.4	1.3	GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.4	12.0	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4	1.2	GO:1902847	regulation of neuronal signal transduction(GO:1902847) regulation of tau-protein kinase activity(GO:1902947) positive regulation of tau-protein kinase activity(GO:1902949) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4	3.7	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.4	2.4	GO:0050917	sensory perception of umami taste(GO:0050917)
0.4	6.4	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.4	4.4	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.4	1.5	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.4	2.5	GO:0006477	protein sulfation(GO:0006477)
0.4	1.8	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.4	2.1	GO:0001812	positive regulation of type I hypersensitivity(GO:0001812)
0.4	4.2	GO:0014029	neural crest formation(GO:0014029)
0.4	2.8	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.4	1.1	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3	4.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.3	3.7	GO:0070327	thyroid hormone transport(GO:0070327)
0.3	1.0	GO:0006552	leucine catabolic process(GO:0006552)
0.3	1.6	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.3	1.3	GO:0018992	germ-line sex determination(GO:0018992)
0.3	1.0	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.3	3.8	GO:0046485	ether lipid metabolic process(GO:0046485)
0.3	1.9	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.3	3.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3	1.5	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.3	1.2	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.3	5.5	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.3	4.0	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.3	2.0	GO:0042746	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.3	4.6	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.3	3.7	GO:0098880	maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.3	0.9	GO:0019677	NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
0.3	1.1	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.3	0.8	GO:0045963	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.3	4.2	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.3	2.3	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3	1.1	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.3	0.8	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3	1.4	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3	2.7	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.3	1.3	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.3	1.3	GO:0045218	zonula adherens maintenance(GO:0045218)
0.3	3.1	GO:2000257	regulation of protein activation cascade(GO:2000257)
0.3	1.0	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.3	1.3	GO:0009758	carbohydrate utilization(GO:0009758)
0.3	0.5	GO:0016107	sesquiterpenoid metabolic process(GO:0006714) polyprenol catabolic process(GO:0016095) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.2	0.2	GO:2000521	negative regulation of immunological synapse formation(GO:2000521) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.2	1.4	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.2	1.0	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.2	1.1	GO:0034552	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2	1.8	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2	1.6	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2	1.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	4.9	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2	0.9	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.2	0.7	GO:0099558	maintenance of synapse structure(GO:0099558)
0.2	0.9	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2	0.9	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.2	1.5	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.2	0.6	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2	0.8	GO:0019585	uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.2	8.6	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.2	0.8	GO:0006004	fucose metabolic process(GO:0006004)
0.2	6.7	GO:0042311	vasodilation(GO:0042311)
0.2	3.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.2	0.6	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.2	2.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.2	1.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2	2.6	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.2	0.5	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2	1.2	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2	3.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.2	1.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.2	2.4	GO:0051969	regulation of transmission of nerve impulse(GO:0051969)
0.2	0.5	GO:0090024	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
0.2	0.5	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.2	0.7	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.2	3.7	GO:0044458	motile cilium assembly(GO:0044458)
0.2	4.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	0.7	GO:0035494	SNARE complex disassembly(GO:0035494)
0.2	0.8	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2	0.7	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.2	0.6	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.2	4.9	GO:0035036	sperm-egg recognition(GO:0035036)
0.2	2.2	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.2	1.2	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.1	9.2	GO:0007566	embryo implantation(GO:0007566)
0.1	0.9	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.1	1.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.1	1.3	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.1	2.1	GO:0001675	acrosome assembly(GO:0001675)
0.1	0.4	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1	0.7	GO:0045356	MyD88-independent toll-like receptor signaling pathway(GO:0002756) positive regulation of chemokine biosynthetic process(GO:0045080) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	0.5	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.1	0.8	GO:0071233	cellular response to leucine(GO:0071233)
0.1	1.4	GO:0034389	lipid particle organization(GO:0034389)
0.1	0.8	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.1	1.0	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.1	0.5	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.1	2.9	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	1.8	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.1	0.7	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.1	0.3	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.1	1.2	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.1	0.5	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1	1.4	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1	0.8	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	2.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.1	2.3	GO:0045116	protein neddylation(GO:0045116)
0.1	0.5	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1	2.0	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	1.7	GO:0019430	removal of superoxide radicals(GO:0019430)
0.1	0.5	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1	0.4	GO:0016240	autophagosome docking(GO:0016240)
0.1	1.2	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1	1.7	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	0.7	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.1	0.3	GO:0018201	peptidyl-glycine modification(GO:0018201)
0.1	0.7	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.1	0.3	GO:0042441	eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
0.1	0.4	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1	1.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	2.5	GO:0015701	bicarbonate transport(GO:0015701)
0.1	2.2	GO:0019835	cytolysis(GO:0019835)
0.1	0.5	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.8	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.1	1.2	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.1	0.7	GO:0034214	protein hexamerization(GO:0034214)
0.1	0.5	GO:0061590	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1	0.8	GO:0032328	alanine transport(GO:0032328)
0.1	0.2	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.1	0.2	GO:0000962	mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.1	1.8	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.8	GO:0006465	signal peptide processing(GO:0006465)
0.1	1.8	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.1	1.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.5	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.9	GO:0032275	luteinizing hormone secretion(GO:0032275)
0.1	1.0	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	0.5	GO:0060290	transdifferentiation(GO:0060290)
0.1	0.4	GO:0060022	hard palate development(GO:0060022)
0.1	0.3	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223) dTTP metabolic process(GO:0046075)
0.1	0.3	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1	1.8	GO:0043171	peptide catabolic process(GO:0043171)
0.1	1.2	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.1	1.4	GO:0060039	pericardium development(GO:0060039)
0.1	0.3	GO:0042045	epithelial fluid transport(GO:0042045)
0.1	0.5	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.2	GO:0043201	response to leucine(GO:0043201)
0.1	0.5	GO:0051013	microtubule severing(GO:0051013)
0.1	0.2	GO:0046462	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1	0.8	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.1	1.7	GO:0030261	chromosome condensation(GO:0030261)
0.1	0.8	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.1	0.3	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.1	1.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.1	0.2	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.1	0.5	GO:0030432	urinary bladder smooth muscle contraction(GO:0014832) peristalsis(GO:0030432)
0.1	1.7	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1	0.2	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1	1.1	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.1	0.1	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1	0.7	GO:0043584	nose development(GO:0043584)
0.1	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.1	0.7	GO:1902065	response to L-glutamate(GO:1902065)
0.1	0.7	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	0.4	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.4	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.1	GO:0042335	cuticle development(GO:0042335) cornification(GO:0070268)
0.0	0.6	GO:0006308	DNA catabolic process(GO:0006308)
0.0	6.2	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
0.0	11.3	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.0	0.2	GO:2000821	regulation of grooming behavior(GO:2000821)
0.0	0.2	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:1901227	negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
0.0	0.8	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.5	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.3	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.0	1.1	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0	1.0	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.2	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.5	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.1	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0	0.4	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	4.9	GO:0007605	sensory perception of sound(GO:0007605)
0.0	0.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.7	GO:0045475	locomotor rhythm(GO:0045475)
0.0	1.7	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	1.0	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.5	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.3	GO:0042048	olfactory behavior(GO:0042048)
0.0	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	1.1	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.2	GO:0051177	meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0	1.3	GO:0016126	sterol biosynthetic process(GO:0016126)
0.0	0.5	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.6	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.2	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.4	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.3	GO:0006265	DNA topological change(GO:0006265)
0.0	0.4	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0070471	uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0	0.4	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.5	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.1	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0	0.2	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.0	1.5	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.3	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.6	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.5	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.2	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.5	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.8	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	1.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.8	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	28.2	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	1.6	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.6	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0019046	viral latency(GO:0019042) release from viral latency(GO:0019046)
0.0	0.3	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.2	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.0	0.1	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
0.0	0.3	GO:0070972	protein localization to endoplasmic reticulum(GO:0070972)
0.0	0.6	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.2	GO:0051451	myoblast migration(GO:0051451)
0.0	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	1.7	GO:0010921	regulation of phosphatase activity(GO:0010921)
0.0	0.5	GO:0042773	ATP synthesis coupled electron transport(GO:0042773)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.6	GO:0008542	visual learning(GO:0008542)
0.0	0.2	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.0	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.2	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.1	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.3	GO:0046496	pyridine nucleotide metabolic process(GO:0019362) nicotinamide nucleotide metabolic process(GO:0046496)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:1904640	response to methionine(GO:1904640)
0.0	0.2	GO:0048679	regulation of axon regeneration(GO:0048679)
0.0	0.5	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.0	5.6	GO:0005975	carbohydrate metabolic process(GO:0005975)
0.0	0.2	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.6	32.0	GO:0005579	membrane attack complex(GO:0005579)
2.4	16.5	GO:0097524	sperm plasma membrane(GO:0097524)
1.3	6.4	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.3	5.1	GO:0001405	presequence translocase-associated import motor(GO:0001405)
1.3	16.4	GO:0042627	chylomicron(GO:0042627)
1.2	3.5	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
1.0	8.2	GO:0005577	fibrinogen complex(GO:0005577)
0.8	9.8	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.7	12.4	GO:0030061	mitochondrial crista(GO:0030061)
0.7	12.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.7	76.5	GO:0072562	blood microparticle(GO:0072562)
0.7	14.1	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.6	1.2	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.5	10.3	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.5	10.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.5	10.4	GO:0005922	connexon complex(GO:0005922)
0.4	1.5	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
0.4	9.9	GO:0005640	nuclear outer membrane(GO:0005640)
0.3	1.7	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.3	1.0	GO:0045203	intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.3	4.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.3	2.6	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.3	1.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.3	7.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.3	1.6	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.3	4.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.2	1.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2	2.5	GO:0032426	stereocilium tip(GO:0032426)
0.2	1.0	GO:0072487	MSL complex(GO:0072487)
0.2	5.4	GO:0001673	male germ cell nucleus(GO:0001673)
0.2	1.9	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2	2.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.2	11.3	GO:0001917	photoreceptor inner segment(GO:0001917)
0.2	1.3	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2	1.0	GO:1990716	axonemal central apparatus(GO:1990716)
0.2	3.2	GO:0031045	dense core granule(GO:0031045)
0.2	0.4	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2	1.7	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2	1.0	GO:0005726	perichromatin fibrils(GO:0005726)
0.2	2.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.2	3.4	GO:0043194	axon initial segment(GO:0043194)
0.2	0.5	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2	23.6	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.2	11.6	GO:0045095	keratin filament(GO:0045095)
0.1	0.7	GO:0061617	MICOS complex(GO:0061617)
0.1	1.1	GO:0032584	growth cone membrane(GO:0032584)
0.1	3.6	GO:0002080	acrosomal membrane(GO:0002080)
0.1	104.9	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.1	0.6	GO:0098536	deuterosome(GO:0098536)
0.1	0.2	GO:0045025	mitochondrial degradosome(GO:0045025)
0.1	1.3	GO:0005915	zonula adherens(GO:0005915)
0.1	0.7	GO:0000125	PCAF complex(GO:0000125)
0.1	0.4	GO:0097453	mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1	2.2	GO:0044292	dendrite terminus(GO:0044292)
0.1	6.8	GO:0005882	intermediate filament(GO:0005882)
0.1	0.5	GO:0070469	respiratory chain(GO:0070469)
0.1	5.4	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	1.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	1.5	GO:0034709	methylosome(GO:0034709)
0.1	0.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	0.5	GO:0097433	dense body(GO:0097433)
0.1	0.6	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	1.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	1.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	0.4	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.5	GO:1990246	uniplex complex(GO:1990246)
0.1	0.6	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	1.3	GO:0030667	secretory granule membrane(GO:0030667)
0.1	22.1	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.1	1.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	0.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	7.6	GO:0031966	mitochondrial membrane(GO:0031966)
0.1	0.6	GO:0000801	central element(GO:0000801)
0.1	1.4	GO:0031430	M band(GO:0031430)
0.0	0.7	GO:0043083	synaptic cleft(GO:0043083)
0.0	10.6	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	1.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.3	GO:0031931	TORC1 complex(GO:0031931)
0.0	50.8	GO:0005615	extracellular space(GO:0005615)
0.0	4.0	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.4	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0	0.7	GO:0001533	cornified envelope(GO:0001533)
0.0	1.6	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	0.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	1.7	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	3.1	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.3	GO:0070652	HAUS complex(GO:0070652)
0.0	1.0	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.0	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.4	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0034455	t-UTP complex(GO:0034455)
0.0	0.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.2	GO:0000795	synaptonemal complex(GO:0000795)
0.0	9.9	GO:0005739	mitochondrion(GO:0005739)
0.0	0.0	GO:0061574	ASAP complex(GO:0061574)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.8	47.5	GO:0004556	alpha-amylase activity(GO:0004556)
5.5	16.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
3.7	11.0	GO:0052852	very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
3.3	10.0	GO:0031714	C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
3.3	22.9	GO:0004062	aryl sulfotransferase activity(GO:0004062)
2.7	13.7	GO:0005534	galactose binding(GO:0005534)
2.5	12.7	GO:0016841	ammonia-lyase activity(GO:0016841)
2.2	28.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
2.0	6.0	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
2.0	5.9	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
1.9	9.3	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
1.8	9.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.7	5.2	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
1.7	6.9	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.7	5.1	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
1.7	50.2	GO:0015020	glucuronosyltransferase activity(GO:0015020)
1.6	6.6	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
1.5	4.5	GO:0002060	purine nucleobase binding(GO:0002060)
1.5	7.4	GO:0004008	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
1.3	12.0	GO:0004859	phospholipase inhibitor activity(GO:0004859)
1.3	3.9	GO:0004925	prolactin receptor activity(GO:0004925)
1.3	34.2	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
1.2	4.7	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
1.1	10.3	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.1	17.0	GO:0008395	steroid hydroxylase activity(GO:0008395)
1.1	3.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.0	4.1	GO:0015057	thrombin receptor activity(GO:0015057)
1.0	3.0	GO:0004736	pyruvate carboxylase activity(GO:0004736)
1.0	3.9	GO:0019166	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.9	8.8	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.9	4.3	GO:0004031	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.8	12.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.8	2.4	GO:0004645	phosphorylase activity(GO:0004645)
0.8	2.3	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.8	3.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.7	4.4	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.7	4.4	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.7	2.8	GO:0055100	adiponectin binding(GO:0055100)
0.6	75.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.6	6.9	GO:0001846	opsonin binding(GO:0001846)
0.6	3.7	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.6	10.0	GO:0043295	glutathione binding(GO:0043295)
0.6	15.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.6	2.8	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.6	2.8	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5	4.3	GO:0004630	phospholipase D activity(GO:0004630)
0.5	5.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.5	4.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.5	5.7	GO:0004000	adenosine deaminase activity(GO:0004000)
0.5	2.4	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.5	3.3	GO:0035375	zymogen binding(GO:0035375)
0.5	1.4	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.4	2.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4	1.3	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.4	1.7	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.4	2.5	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4	2.5	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.4	1.9	GO:0043532	angiostatin binding(GO:0043532)
0.4	1.1	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3	2.4	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.3	1.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.3	1.0	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3	1.6	GO:0034056	estrogen response element binding(GO:0034056)
0.3	3.5	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3	3.8	GO:0019841	retinol binding(GO:0019841)
0.3	1.9	GO:0019767	IgE receptor activity(GO:0019767)
0.3	0.9	GO:0004775	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.3	1.8	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3	3.7	GO:0098879	structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.3	0.8	GO:0071886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
0.3	4.0	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.3	2.2	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3	3.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.3	0.5	GO:0045340	mercury ion binding(GO:0045340)
0.3	2.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3	4.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.3	3.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.3	0.5	GO:0045550	geranylgeranyl reductase activity(GO:0045550)
0.3	3.0	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.2	1.0	GO:0051870	methotrexate binding(GO:0051870)
0.2	1.2	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.2	0.9	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.2	1.1	GO:0005042	netrin receptor activity(GO:0005042)
0.2	0.9	GO:0061665	SUMO ligase activity(GO:0061665)
0.2	0.9	GO:0008940	nitrate reductase activity(GO:0008940)
0.2	3.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.2	0.9	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.2	0.6	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.2	5.9	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.2	4.0	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.2	1.8	GO:0010181	FMN binding(GO:0010181)
0.2	1.0	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2	1.7	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	1.8	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.2	2.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.2	1.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.2	0.4	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2	3.6	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	1.9	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.2	0.5	GO:0001847	opsonin receptor activity(GO:0001847)
0.2	0.5	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2	0.7	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.2	4.0	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2	0.8	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.2	0.3	GO:0016530	metallochaperone activity(GO:0016530)
0.2	1.3	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2	13.1	GO:0051087	chaperone binding(GO:0051087)
0.2	2.5	GO:0051787	misfolded protein binding(GO:0051787)
0.2	0.5	GO:0016015	morphogen activity(GO:0016015)
0.1	1.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.6	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	3.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.4	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	1.8	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	4.1	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.1	4.3	GO:0042165	neurotransmitter binding(GO:0042165)
0.1	0.4	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	2.3	GO:0070330	aromatase activity(GO:0070330)
0.1	0.8	GO:0070728	leucine binding(GO:0070728)
0.1	1.0	GO:0016885	CoA carboxylase activity(GO:0016421) ligase activity, forming carbon-carbon bonds(GO:0016885)
0.1	1.7	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	1.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	0.7	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1	1.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.7	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.5	GO:0033149	FFAT motif binding(GO:0033149)
0.1	1.4	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.9	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	3.0	GO:0042056	chemoattractant activity(GO:0042056)
0.1	1.2	GO:0051378	serotonin binding(GO:0051378)
0.1	0.8	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	0.4	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	3.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	0.5	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	1.7	GO:0050811	GABA receptor binding(GO:0050811)
0.1	1.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	1.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.5	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.1	0.8	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	2.8	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.1	1.5	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.4	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.6	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	8.6	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.1	1.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	1.8	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	2.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	1.0	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	0.3	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1	0.3	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	0.3	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	1.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	1.6	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.1	1.7	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.5	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.1	1.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	0.7	GO:0070628	proteasome binding(GO:0070628)
0.1	15.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	6.6	GO:0003823	antigen binding(GO:0003823)
0.1	8.9	GO:0004519	endonuclease activity(GO:0004519)
0.1	1.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.6	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.1	2.4	GO:0005109	frizzled binding(GO:0005109)
0.1	1.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	7.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.7	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	1.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	0.9	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	2.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	1.1	GO:0017171	serine hydrolase activity(GO:0017171)
0.1	0.2	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.7	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.1	0.7	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	21.0	GO:0005549	odorant binding(GO:0005549)
0.1	0.3	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1	0.9	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	1.0	GO:0008199	ferric iron binding(GO:0008199)
0.1	5.1	GO:0016407	acetyltransferase activity(GO:0016407)
0.0	0.1	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0	0.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.5	GO:0005123	death receptor binding(GO:0005123)
0.0	0.3	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	1.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	2.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	1.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	2.0	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.6	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	1.9	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.4	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.6	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.0	0.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.5	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0019808	polyamine binding(GO:0019808)
0.0	1.5	GO:0038024	cargo receptor activity(GO:0038024)
0.0	3.9	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.4	GO:0035497	cAMP response element binding(GO:0035497)
0.0	1.6	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.3	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.8	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.5	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.2	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.2	GO:0008097	5S rRNA binding(GO:0008097)
0.0	3.0	GO:0008083	growth factor activity(GO:0008083)
0.0	0.7	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.0	0.3	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.3	GO:0016410	N-acyltransferase activity(GO:0016410)
0.0	0.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	1.3	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0	0.4	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	14.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.3	16.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	4.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	4.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	2.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	49.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	4.9	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	2.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	9.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	0.8	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	3.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	1.7	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	1.4	PID RAS PATHWAY	Regulation of Ras family activation
0.1	0.9	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.7	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	11.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.7	PID MYC PATHWAY	C-MYC pathway
0.0	1.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.6	PID P73PATHWAY	p73 transcription factor network
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.7	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.8	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.7	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	6.9	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
1.9	65.2	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
1.4	28.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
1.3	17.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
1.1	14.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.6	19.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.6	11.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.6	1.7	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.5	4.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.4	6.7	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.4	7.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.4	3.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.4	3.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	6.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.3	9.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.3	3.0	REACTOME DEFENSINS	Genes involved in Defensins
0.3	4.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.3	12.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.3	11.9	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.3	2.4	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.3	4.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	9.3	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.2	6.0	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2	8.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.2	3.9	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.2	3.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	2.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	1.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	1.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.2	3.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	1.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2	1.9	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2	6.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	2.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	3.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	3.9	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	20.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	1.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	3.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	2.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	2.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	0.9	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	0.7	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	1.6	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	1.0	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	1.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.0	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	1.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	2.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	1.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	2.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.5	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.8	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	1.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.6	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.1	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins

Results for Dlx5_Dlx4

Z-value: 0.70

Motif logo

Transcription factors associated with Dlx5_Dlx4

Activity-expression correlation:

Activity profile of Dlx5_Dlx4 motif

Sorted Z-values of Dlx5_Dlx4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Dlx5_Dlx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: