Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Fli1

Z-value: 0.87

Motif logo

logo of

Transcription factors associated with Fli1

Gene Symbol Gene ID Gene Info
Fli1
ENSRNOG00000008904 Fli-1 proto-oncogene, ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fli1rn6_v1_chr8_-_33661049_336610490.035.5e-01Click!

Activity profile of Fli1 motif

Sorted Z-values of Fli1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_80594136 133.20 ENSRNOT00000024800
Apoc2
apolipoprotein C2
chr1_+_150797084 83.63 ENSRNOT00000018990
Nox4
NADPH oxidase 4
chr8_-_62458301 68.12 ENSRNOT00000021653
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
chr8_+_128044084 54.17 ENSRNOT00000019106
Xylb
xylulokinase
chr20_-_9876008 39.83 ENSRNOT00000001537
Tff2
trefoil factor 2
chr4_+_14039977 38.66 ENSRNOT00000091249
ENSRNOT00000075878
Cd36
CD36 molecule
chr7_+_143754892 37.45 ENSRNOT00000085896
Soat2
sterol O-acyltransferase 2
chr1_-_259287684 37.26 ENSRNOT00000054724
Cyp2c22
cytochrome P450, family 2, subfamily c, polypeptide 22
chr1_+_80383050 32.74 ENSRNOT00000023451
Exoc3l2
exocyst complex component 3-like 2
chr1_-_20155960 28.67 ENSRNOT00000061389
Samd3
sterile alpha motif domain containing 3
chr6_-_127653124 26.17 ENSRNOT00000047324
Serpina11
serpin family A member 11
chr10_+_65733991 25.18 ENSRNOT00000013698
Slc46a1
solute carrier family 46 member 1
chr7_-_67345295 23.79 ENSRNOT00000087045
ENSRNOT00000005829
Avpr1a
arginine vasopressin receptor 1A
chr18_-_59819113 22.18 ENSRNOT00000065939
RGD1562699
RGD1562699
chr15_-_45550285 21.52 ENSRNOT00000012948
Gucy1b2
guanylate cyclase 1 soluble subunit beta 2
chr4_-_51199570 19.19 ENSRNOT00000010788
Slc13a1
solute carrier family 13 member 1
chr1_+_61445672 17.26 ENSRNOT00000089298
LOC108348215
zinc finger protein 420-like
chr1_+_248723397 16.77 ENSRNOT00000072188
LOC100911854
mannose-binding protein C-like
chr4_-_145699577 16.24 ENSRNOT00000014377
Sec13
SEC13 homolog, nuclear pore and COPII coat complex component
chr8_-_6203515 16.08 ENSRNOT00000087278
ENSRNOT00000031189
ENSRNOT00000008074
ENSRNOT00000085285
ENSRNOT00000007866
Yap1
yes-associated protein 1
chr20_-_20680675 15.02 ENSRNOT00000087085
Rhobtb1
Rho-related BTB domain containing 1
chr18_-_80865584 15.01 ENSRNOT00000021750
Tshz1
teashirt zinc finger homeobox 1
chr7_+_23913830 14.81 ENSRNOT00000006570
Rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr8_+_37156619 12.73 ENSRNOT00000070856
Gm17689
predicted gene, 17689
chr7_-_2623781 12.31 ENSRNOT00000004173
Spryd4
SPRY domain containing 4
chr2_+_196608496 11.37 ENSRNOT00000091681
Arnt
aryl hydrocarbon receptor nuclear translocator
chr7_-_70926903 11.26 ENSRNOT00000031005
Lrp1
LDL receptor related protein 1
chr9_-_17212628 10.84 ENSRNOT00000002656
ENSRNOT00000007876
RGD1562399
similar to 40S ribosomal protein S2
chr13_-_111972603 10.47 ENSRNOT00000007870
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
chr4_-_82229397 10.24 ENSRNOT00000089432
Hoxa13
homeo box A13
chrX_+_159560292 10.09 ENSRNOT00000087250
Vgll1
vestigial like family member 1
chr14_-_84189266 9.93 ENSRNOT00000005934
Tcn2
transcobalamin 2
chr2_+_248219428 9.88 ENSRNOT00000037181
LOC685067
similar to guanylate binding protein family, member 6
chr12_+_41636994 9.77 ENSRNOT00000001882
Sdsl
serine dehydratase-like
chr4_-_163528220 9.76 ENSRNOT00000090813
Klri1
killer cell lectin-like receptor family I member 1
chr3_+_147992754 9.10 ENSRNOT00000055412
Defb28
defensin beta 28
chr1_-_64021321 8.94 ENSRNOT00000090819
Rps9
ribosomal protein S9
chr3_-_176744377 8.49 ENSRNOT00000017787
Helz2
helicase with zinc finger 2, transcriptional coactivator
chr18_+_63098144 8.41 ENSRNOT00000024968
Cidea
cell death-inducing DFFA-like effector a
chr4_-_158705885 8.07 ENSRNOT00000087115
ENSRNOT00000026685
Ntf3
neurotrophin 3
chrX_+_80213332 7.33 ENSRNOT00000042827
Sh3bgrl
SH3 domain binding glutamate-rich protein like
chr18_-_55992885 7.02 ENSRNOT00000025881
Ndst1
N-deacetylase and N-sulfotransferase 1
chr5_+_164751440 6.94 ENSRNOT00000010558
RGD1305350
similar to RIKEN cDNA 2510039O18
chr4_-_156426760 6.73 ENSRNOT00000014028
LOC103690024
peroxisomal targeting signal 1 receptor-like
chr3_-_103345333 6.54 ENSRNOT00000071479
LOC100909692
olfactory receptor 4F3/4F16/4F29-like
chr5_+_173024335 6.52 ENSRNOT00000023097
Slc35e2b
solute carrier family 35, member E2B
chr16_+_7758996 6.28 ENSRNOT00000061063
Btd
biotinidase
chr15_-_34322115 5.78 ENSRNOT00000026734
Tm9sf1
transmembrane 9 superfamily member 1
chr17_+_57074525 5.60 ENSRNOT00000020012
ENSRNOT00000074146
Crem
cAMP responsive element modulator
chr12_+_25264192 5.51 ENSRNOT00000079392
Gtf2ird1
GTF2I repeat domain containing 1
chr12_+_25264400 5.50 ENSRNOT00000087656
Gtf2ird1
GTF2I repeat domain containing 1
chr15_-_35166211 5.45 ENSRNOT00000059662
LOC691670
similar to natural killer cell protease 7
chr17_-_14828329 5.43 ENSRNOT00000022830
Barx1
BARX homeobox 1
chr3_+_4106477 5.21 ENSRNOT00000078985
AABR07051251.1

chrX_+_15378789 5.17 ENSRNOT00000029272
Gata1
GATA binding protein 1
chr1_+_264504591 5.16 ENSRNOT00000050076
Pax2
paired box 2
chr3_-_67668772 5.09 ENSRNOT00000010247
Frzb
frizzled-related protein
chr3_+_33641616 5.06 ENSRNOT00000051953
Epc2
enhancer of polycomb homolog 2
chr4_+_156050054 4.79 ENSRNOT00000039855
Clec4a
C-type lectin domain family 4, member A
chr7_+_25919867 4.78 ENSRNOT00000009625
ENSRNOT00000090153
Ric8b
RIC8 guanine nucleotide exchange factor B
chr10_-_11174861 4.78 ENSRNOT00000006680
Glis2
GLIS family zinc finger 2
chr8_+_48805684 4.76 ENSRNOT00000064041
Bcl9l
B-cell CLL/lymphoma 9-like
chr1_+_225690756 4.66 ENSRNOT00000027498
Psbpc2
prostatic steroid-binding protein C2
chr20_+_47596575 4.54 ENSRNOT00000087230
ENSRNOT00000064905
Scml4
sex comb on midleg-like 4 (Drosophila)
chr19_-_39087880 4.50 ENSRNOT00000070822
Chtf8
chromosome transmission fidelity factor 8
chr3_-_7203420 4.49 ENSRNOT00000015236
Gfi1b
growth factor independent 1B transcriptional repressor
chr10_+_4538111 4.46 ENSRNOT00000084151
Zc3h7a
zinc finger CCCH type containing 7 A
chr5_-_135628750 4.44 ENSRNOT00000079236
AC126292.3

chr3_+_5555807 4.43 ENSRNOT00000007677
Cacfd1
calcium channel flower domain containing 1
chr20_-_32353677 4.38 ENSRNOT00000035355
Stox1
storkhead box 1
chr8_+_111239922 4.36 ENSRNOT00000077948
AABR07071358.1

chr4_+_120843453 4.35 ENSRNOT00000022534
Tpra1
transmembrane protein adipocyte associated 1
chr19_+_38619764 4.29 ENSRNOT00000027225
LOC100360573
ribosomal protein S12-like
chr12_-_23841049 4.29 ENSRNOT00000031555
Hspb1
heat shock protein family B (small) member 1
chrX_+_156355376 4.28 ENSRNOT00000078304
Lage3
L antigen family, member 3
chr2_+_250600823 4.24 ENSRNOT00000083750
Sep15
selenoprotein 15
chr10_-_44256945 4.20 ENSRNOT00000003818
Olr1432
olfactory receptor 1432
chr15_-_20783063 4.19 ENSRNOT00000083268
Bmp4
bone morphogenetic protein 4
chr10_-_65502936 4.17 ENSRNOT00000089615
Supt6h
SPT6 homolog, histone chaperone
chr5_+_64566804 4.00 ENSRNOT00000073192
LOC103690035
TGF-beta receptor type-1-like
chr10_+_67325347 3.95 ENSRNOT00000079002
ENSRNOT00000085914
Suz12
suppressor of zeste 12 homolog (Drosophila)
chrX_+_157759624 3.81 ENSRNOT00000003192
LOC686087
similar to motile sperm domain containing 1
chrX_+_43625169 3.80 ENSRNOT00000086311
Sat1
spermidine/spermine N1-acetyl transferase 1
chr5_-_150390099 3.79 ENSRNOT00000014479
Ythdf2
YTH N(6)-methyladenosine RNA binding protein 2
chr9_-_50884596 3.77 ENSRNOT00000016285
Kdelc1
KDEL motif containing 1
chr2_+_29410579 3.76 ENSRNOT00000023180
Zfp366
zinc finger protein 366
chr1_+_190200324 3.65 ENSRNOT00000001933
Abca16
ATP-binding cassette, subfamily A (ABC1), member 16
chr3_-_103400272 3.62 ENSRNOT00000046527
Olr790
olfactory receptor 790
chr14_-_86796378 3.48 ENSRNOT00000092021
Myo1g
myosin IG
chr20_+_12773427 3.45 ENSRNOT00000001695
Col6a2
collagen type VI alpha 2 chain
chr3_+_66593934 3.42 ENSRNOT00000008046
Ssfa2
sperm specific antigen 2
chr18_+_55666027 3.36 ENSRNOT00000045950
RGD1305184
similar to CDNA sequence BC023105
chr1_+_256370850 3.28 ENSRNOT00000030962
Cyp26c1
cytochrome P450, family 26, subfamily C, polypeptide 1
chr5_-_147907733 2.99 ENSRNOT00000032558
Tmem39b
transmembrane protein 39b
chr1_+_99599620 2.90 ENSRNOT00000024690
Ctu1
cytosolic thiouridylase subunit 1
chr5_+_173237642 2.82 ENSRNOT00000068770
Ankrd65
ankyrin repeat domain 65
chr20_+_48881194 2.68 ENSRNOT00000000304
Rtn4ip1
reticulon 4 interacting protein 1
chr5_+_57738321 2.66 ENSRNOT00000063849
Ubap1
ubiquitin-associated protein 1
chr2_+_154604832 2.62 ENSRNOT00000013777
Vom2r44
vomeronasal 2 receptor 44
chr18_+_57286322 2.56 ENSRNOT00000026174
Sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr20_+_18492169 2.54 ENSRNOT00000046536
LOC103690821
60S ribosomal protein L39
chr16_-_69242028 2.54 ENSRNOT00000019002
Zfp703
zinc finger protein 703
chr4_-_170932618 2.50 ENSRNOT00000007779
Arhgdib
Rho GDP dissociation inhibitor beta
chr8_-_79862974 2.47 ENSRNOT00000091386
AC128582.1

chr7_-_140546908 2.41 ENSRNOT00000077502
Kmt2d
lysine methyltransferase 2D
chr16_+_20020444 2.35 ENSRNOT00000024827
Pgls
6-phosphogluconolactonase
chr7_-_116010938 2.35 ENSRNOT00000076807
ENSRNOT00000076047
D730001G18Rik
RIKEN cDNA D730001G18 gene
chrX_-_4957529 2.20 ENSRNOT00000000173
Dusp21
dual specificity phosphatase 21
chr7_+_137680530 2.20 ENSRNOT00000006970
Arid2
AT-rich interaction domain 2
chrX_-_113474164 2.19 ENSRNOT00000046804
Gucy2f
guanylate cyclase 2F
chr8_+_20230082 2.16 ENSRNOT00000044463
Olr1165
olfactory receptor 1165
chr10_+_45893018 2.14 ENSRNOT00000004280
ENSRNOT00000086710
Nlrp3
NLR family, pyrin domain containing 3
chr4_-_156563438 2.12 ENSRNOT00000045305
Vom2r51
vomeronasal 2 receptor, 51
chr10_-_13580821 2.00 ENSRNOT00000009735
Ntn3
netrin 3
chr15_-_30019055 1.83 ENSRNOT00000073984
AABR07017681.1

chr10_+_46840113 1.82 ENSRNOT00000086083
ENSRNOT00000079133
Myo15a
myosin XVA
chr1_-_24302298 1.81 ENSRNOT00000083452
Sgk1
serum/glucocorticoid regulated kinase 1
chr3_-_24601063 1.78 ENSRNOT00000037043
LOC100362366
40S ribosomal protein S17-like
chr16_-_69884962 1.65 ENSRNOT00000078635
Cnga2
cyclic nucleotide gated channel alpha 2
chr9_+_81427730 1.64 ENSRNOT00000019109
ENSRNOT00000081711
Cxcr2
C-X-C motif chemokine receptor 2
chrX_+_158569056 1.63 ENSRNOT00000074170
LOC102550080
placenta-specific protein 1-like
chr19_+_39087990 1.63 ENSRNOT00000027553
Utp4
UTP4 small subunit processome component
chr12_-_17186679 1.58 ENSRNOT00000001730
Uncx
UNC homeobox
chr8_+_49354115 1.56 ENSRNOT00000032837
Mpzl3
myelin protein zero-like 3
chr5_+_159534202 1.56 ENSRNOT00000010993
Mfap2
microfibrillar-associated protein 2
chr13_-_72869396 1.48 ENSRNOT00000093563
RGD1304622
similar to 6820428L09 protein
chr20_-_32080088 1.46 ENSRNOT00000080773
Supv3l1
Suv3 like RNA helicase
chr1_-_85317968 1.40 ENSRNOT00000026891
Gmfg
glia maturation factor, gamma
chr8_+_79159370 1.39 ENSRNOT00000086841
Rfx7
regulatory factor X, 7
chr2_-_250600517 1.39 ENSRNOT00000016872
Hs2st1
heparan sulfate 2-O-sulfotransferase 1
chr16_+_35934970 1.36 ENSRNOT00000084707
ENSRNOT00000016474
Galnt7
polypeptide N-acetylgalactosaminyltransferase 7
chr17_+_6684621 1.36 ENSRNOT00000089138
RGD1311345
similar to CG9752-PA
chr6_-_111572949 1.32 ENSRNOT00000016884
RGD1565693
similar to GLE1-like, RNA export mediator isoform 1
chr10_-_61577412 1.28 ENSRNOT00000003696
Pafah1b1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
chr12_+_12756452 1.21 ENSRNOT00000001382
ENSRNOT00000092462
Ankrd61
ankyrin repeat domain 61
chr5_+_137257637 1.17 ENSRNOT00000093001
Elovl1
ELOVL fatty acid elongase 1
chr5_+_151573092 1.17 ENSRNOT00000011049
Slc9a1
solute carrier family 9 member A1
chr14_-_45863877 1.15 ENSRNOT00000002977
Pgm2
phosphoglucomutase 2
chr1_+_45923222 1.07 ENSRNOT00000092976
ENSRNOT00000084454
ENSRNOT00000022939
Arid1b
AT-rich interaction domain 1B
chr3_-_33075685 1.05 ENSRNOT00000006937
Orc4
origin recognition complex, subunit 4
chr20_-_6556350 0.97 ENSRNOT00000035819
Lemd2
LEM domain containing 2
chr7_+_107467260 0.94 ENSRNOT00000009240
ENSRNOT00000077382
Tg
thyroglobulin
chr2_-_27287605 0.77 ENSRNOT00000034041
Ankdd1b
ankyrin repeat and death domain containing 1B
chr3_+_43255567 0.71 ENSRNOT00000044419
Gpd2
glycerol-3-phosphate dehydrogenase 2
chr18_-_49937522 0.63 ENSRNOT00000033254
Zfp608
zinc finger protein 608
chr15_-_29246222 0.60 ENSRNOT00000081806
AABR07017617.1

chr11_+_86852711 0.54 ENSRNOT00000002581
Dgcr8
DGCR8 microprocessor complex subunit
chr9_-_24383679 0.53 ENSRNOT00000040542
Crisp1
cysteine-rich secretory protein 1
chr2_+_266315036 0.50 ENSRNOT00000055245
Wls
wntless Wnt ligand secretion mediator
chr5_+_117877594 0.47 ENSRNOT00000011631
Atg4c
autophagy related 4C, cysteine peptidase
chr7_-_13425311 0.42 ENSRNOT00000060455
Olr1076
olfactory receptor 1076
chr1_+_217699180 0.40 ENSRNOT00000042579
LOC100364769
LRRG00136-like
chr11_-_65209268 0.29 ENSRNOT00000077612
Gsk3b
glycogen synthase kinase 3 beta
chr14_+_100415668 0.27 ENSRNOT00000008057
C1d
C1D nuclear receptor co-repressor
chr20_-_11528332 0.27 ENSRNOT00000038419
Tspear
thrombospondin-type laminin G domain and EAR repeats
chr4_+_78735279 0.21 ENSRNOT00000011970
Malsu1
mitochondrial assembly of ribosomal large subunit 1
chr14_+_70780623 0.16 ENSRNOT00000083871
ENSRNOT00000058803
Ldb2
LIM domain binding 2
chr2_-_230356919 0.12 ENSRNOT00000038509
Sec24b
SEC24 homolog B, COPII coat complex component

Network of associatons between targets according to the STRING database.

First level regulatory network of Fli1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
44.4 133.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
18.1 54.2 GO:0042732 D-xylose metabolic process(GO:0042732)
13.6 68.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
7.9 23.8 GO:0042631 cellular response to water deprivation(GO:0042631) positive regulation of glycogen catabolic process(GO:0045819)
6.4 38.7 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
6.3 25.2 GO:0051958 methotrexate transport(GO:0051958)
5.7 39.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
4.6 83.6 GO:0050667 homocysteine metabolic process(GO:0050667)
4.2 37.5 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
3.5 10.5 GO:0006713 glucocorticoid catabolic process(GO:0006713)
3.4 10.2 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
3.0 9.0 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
2.8 11.3 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
2.7 16.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
2.5 15.0 GO:0060023 soft palate development(GO:0060023)
2.2 6.7 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
2.2 8.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
2.0 8.1 GO:0007403 glial cell fate determination(GO:0007403)
2.0 9.9 GO:0015889 cobalamin transport(GO:0015889)
1.8 7.0 GO:0030210 heparin biosynthetic process(GO:0030210)
1.7 5.2 GO:0090202 regulation of primitive erythrocyte differentiation(GO:0010725) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.7 5.2 GO:0035566 regulation of metanephros size(GO:0035566)
1.7 5.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
1.6 11.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.6 37.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.4 4.3 GO:1903544 cellular response to interleukin-11(GO:0071348) response to butyrate(GO:1903544)
1.4 1.4 GO:0030202 heparin metabolic process(GO:0030202)
1.3 14.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.2 8.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.2 16.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.1 19.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
1.1 5.6 GO:0070827 chromatin maintenance(GO:0070827)
1.0 3.8 GO:0032919 spermine acetylation(GO:0032919)
0.9 3.8 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.8 2.5 GO:0071461 cellular response to redox state(GO:0071461)
0.8 3.3 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.8 11.4 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.6 4.5 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.6 4.4 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.6 2.9 GO:0034227 tRNA thio-modification(GO:0034227)
0.5 2.1 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713) positive regulation of T-helper 17 type immune response(GO:2000318)
0.5 4.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 3.5 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.5 2.4 GO:0001555 oocyte growth(GO:0001555)
0.4 23.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.4 16.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.4 4.0 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 1.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.4 4.3 GO:0040016 embryonic cleavage(GO:0040016)
0.3 2.3 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.3 1.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 1.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.3 4.0 GO:0042118 endothelial cell activation(GO:0042118)
0.2 2.6 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 1.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 2.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 1.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.2 1.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.2 1.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 3.8 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 6.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.2 1.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 2.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 1.2 GO:0035338 fatty acid elongation, monounsaturated fatty acid(GO:0034625) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 3.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.5 GO:0051697 protein delipidation(GO:0051697)
0.2 5.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.7 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 2.3 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.1 4.8 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.9 GO:0015705 iodide transport(GO:0015705)
0.1 0.5 GO:0031053 primary miRNA processing(GO:0031053)
0.1 5.4 GO:0048536 spleen development(GO:0048536)
0.1 0.3 GO:0071282 cellular response to iron(II) ion(GO:0071282)
0.1 25.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 1.0 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 2.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.5 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.4 GO:0006400 tRNA modification(GO:0006400)
0.0 1.6 GO:0051289 protein homotetramerization(GO:0051289)
0.0 5.8 GO:0006914 autophagy(GO:0006914)
0.0 4.9 GO:0016485 protein processing(GO:0016485)
0.0 4.8 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 14.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
22.2 133.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
8.4 83.6 GO:0043020 NADPH oxidase complex(GO:0043020)
5.4 16.1 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
1.9 14.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.8 16.2 GO:0061700 GATOR2 complex(GO:0061700)
1.3 5.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.9 23.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.7 63.8 GO:0031526 brush border membrane(GO:0031526)
0.6 4.0 GO:0001739 sex chromatin(GO:0001739)
0.5 4.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 1.5 GO:0045025 mitochondrial degradosome(GO:0045025)
0.5 4.3 GO:0097512 cardiac myofibril(GO:0097512)
0.4 37.5 GO:0005903 brush border(GO:0005903)
0.3 6.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 1.6 GO:0034455 t-UTP complex(GO:0034455)
0.3 2.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.3 2.7 GO:0000813 ESCRT I complex(GO:0000813)
0.3 2.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 20.2 GO:0005581 collagen trimer(GO:0005581)
0.2 5.8 GO:0000421 autophagosome membrane(GO:0000421)
0.2 2.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 4.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 5.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 8.4 GO:0005811 lipid particle(GO:0005811)
0.1 10.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 113.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 3.3 GO:0090544 BAF-type complex(GO:0090544)
0.1 3.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.9 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 11.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 11.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 23.9 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.1 1.6 GO:0042629 mast cell granule(GO:0042629)
0.1 2.1 GO:0032420 stereocilium(GO:0032420)
0.1 6.9 GO:0016363 nuclear matrix(GO:0016363)
0.1 5.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 7.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 63.8 GO:0005615 extracellular space(GO:0005615)
0.0 9.2 GO:0005938 cell cortex(GO:0005938)
0.0 0.5 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 4.3 GO:0005840 ribosome(GO:0005840)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
44.4 133.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
9.9 88.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
7.9 23.8 GO:0031893 vasopressin receptor binding(GO:0031893)
7.7 38.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
6.3 25.2 GO:0015350 methotrexate transporter activity(GO:0015350)
4.9 68.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
3.8 11.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
3.5 10.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.8 39.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.1 6.3 GO:0047708 biotinidase activity(GO:0047708)
1.8 8.9 GO:1990932 5.8S rRNA binding(GO:1990932)
1.6 54.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
1.4 4.2 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
1.3 14.8 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
1.3 6.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.3 37.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.3 37.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
1.3 3.8 GO:0019809 spermidine binding(GO:0019809)
1.2 9.9 GO:0031419 cobalamin binding(GO:0031419)
1.2 19.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
1.2 7.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.1 3.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
1.0 8.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.9 23.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 1.6 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.5 11.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.5 16.1 GO:0070064 proline-rich region binding(GO:0070064)
0.5 4.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 3.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.5 4.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 4.2 GO:0039706 co-receptor binding(GO:0039706)
0.3 5.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 1.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.3 1.6 GO:0070051 fibrinogen binding(GO:0070051)
0.3 1.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.7 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 1.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 26.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 5.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 2.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 4.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 1.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 3.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 4.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 4.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 5.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 5.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.9 GO:0000049 tRNA binding(GO:0000049)
0.0 15.0 GO:0003924 GTPase activity(GO:0003924)
0.0 2.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 8.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 3.4 GO:0005525 GTP binding(GO:0005525)
0.0 2.3 GO:0048029 monosaccharide binding(GO:0048029)
0.0 2.5 GO:0005496 steroid binding(GO:0005496)
0.0 2.6 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 1.5 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 3.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.3 GO:0044212 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.0 1.8 GO:0003774 motor activity(GO:0003774)
0.0 25.3 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 3.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 13.1 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 14.0 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 83.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.5 11.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.5 16.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 11.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 8.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 5.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 5.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 5.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 24.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 4.2 PID BMP PATHWAY BMP receptor signaling
0.1 1.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 5.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 4.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
22.7 68.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
7.8 133.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.4 19.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.0 16.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.7 16.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.5 4.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.5 36.7 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.5 11.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.4 25.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 10.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.3 8.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 3.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 3.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 8.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 23.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 16.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.1 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.1 3.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 5.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.3 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates