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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Foxf2

Z-value: 0.86

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Transcription factors associated with Foxf2

Gene Symbol Gene ID Gene Info

Activity profile of Foxf2 motif

Sorted Z-values of Foxf2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_89597138 56.37 ENSRNOT00000004662
Apoa2
apolipoprotein A2
chr18_-_24929091 44.51 ENSRNOT00000019596
Proc
protein C
chr10_+_56662242 43.62 ENSRNOT00000086919
Asgr1
asialoglycoprotein receptor 1
chr8_-_115981910 42.42 ENSRNOT00000019867
Dock3
dedicator of cyto-kinesis 3
chr11_-_81660395 32.96 ENSRNOT00000048739
Fetub
fetuin B
chr3_-_101474890 32.70 ENSRNOT00000091869
Bbox1
gamma-butyrobetaine hydroxylase 1
chr2_-_182035032 32.63 ENSRNOT00000009813
Fgb
fibrinogen beta chain
chr18_+_59748444 32.60 ENSRNOT00000024752
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr7_-_119689938 32.13 ENSRNOT00000000200
Tmprss6
transmembrane protease, serine 6
chr7_+_93975451 29.99 ENSRNOT00000011379
Colec10
collectin subfamily member 10
chr5_+_124300477 29.93 ENSRNOT00000010100
C8b
complement C8 beta chain
chr13_-_80862963 26.22 ENSRNOT00000004864
Fmo3
flavin containing monooxygenase 3
chr5_-_19368431 25.80 ENSRNOT00000012819
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
chr1_+_264741911 25.51 ENSRNOT00000019956
Sema4g
semaphorin 4G
chr2_-_100249811 22.37 ENSRNOT00000086760
Hnf4g
hepatocyte nuclear factor 4, gamma
chr3_-_168018410 21.58 ENSRNOT00000087579
Bcas1
breast carcinoma amplified sequence 1
chr4_-_176528110 20.66 ENSRNOT00000049569
Slco1a2
solute carrier organic anion transporter family, member 1A2
chr10_+_103395511 20.11 ENSRNOT00000004256
Gprc5c
G protein-coupled receptor, class C, group 5, member C
chr10_-_71849293 19.90 ENSRNOT00000003799
Lhx1
LIM homeobox 1
chr1_-_90978907 18.12 ENSRNOT00000072819
Clip3
CAP-GLY domain containing linker protein 3
chr1_+_88750462 16.85 ENSRNOT00000028247
LOC108348122
CAP-Gly domain-containing linker protein 3
chr12_-_10391270 16.64 ENSRNOT00000092340
Wasf3
WAS protein family, member 3
chr3_+_142383278 16.01 ENSRNOT00000017742
Foxa2
forkhead box A2
chr15_-_28313841 15.68 ENSRNOT00000085897
Ndrg2
NDRG family member 2
chr5_+_120340646 15.08 ENSRNOT00000086259
ENSRNOT00000086539
Dnajc6
DnaJ heat shock protein family (Hsp40) member C6
chr4_+_153921115 14.81 ENSRNOT00000018821
Slc6a12
solute carrier family 6 member 12
chr6_-_108167185 14.35 ENSRNOT00000015545
Aldh6a1
aldehyde dehydrogenase 6 family, member A1
chr8_+_94686938 14.11 ENSRNOT00000013285
Ripply2
ripply transcriptional repressor 2
chr3_+_5519990 13.89 ENSRNOT00000070873
ENSRNOT00000007640
Adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr1_+_154606490 13.64 ENSRNOT00000024095
Ccdc89
coiled-coil domain containing 89
chr12_+_21767606 13.41 ENSRNOT00000059602
LOC103691013
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr4_+_152630469 13.22 ENSRNOT00000013721
Ninj2
ninjurin 2
chr1_-_156327352 12.92 ENSRNOT00000074282
LOC100911776
coiled-coil domain-containing protein 89-like
chr5_-_173484986 12.44 ENSRNOT00000064207
ENSRNOT00000055319
Ttll10
tubulin tyrosine ligase like 10
chr1_+_72545596 12.19 ENSRNOT00000022698
Shisa7
shisa family member 7
chr8_+_52127632 12.19 ENSRNOT00000079797
Cadm1
cell adhesion molecule 1
chr1_+_162890475 12.00 ENSRNOT00000034886
Gdpd4
glycerophosphodiester phosphodiesterase domain containing 4
chr5_-_114940364 11.90 ENSRNOT00000038196
AABR07049299.1

chr9_+_118849302 11.88 ENSRNOT00000087592
Dlgap1
DLG associated protein 1
chr1_-_101773508 11.35 ENSRNOT00000067430
Sult2b1
sulfotransferase family 2B member 1
chr14_-_21127868 11.17 ENSRNOT00000020608
ENSRNOT00000092172
Rufy3
RUN and FYVE domain containing 3
chr8_+_52127399 11.06 ENSRNOT00000052392
Cadm1
cell adhesion molecule 1
chr19_-_11669578 10.88 ENSRNOT00000026373
Gnao1
G protein subunit alpha o1
chr4_+_57855416 10.60 ENSRNOT00000029608
Cpa2
carboxypeptidase A2
chr2_-_3124543 10.28 ENSRNOT00000036547
Fam81b
family with sequence similarity 81, member B
chr8_-_78233430 9.99 ENSRNOT00000083220
Cgnl1
cingulin-like 1
chr13_+_26172243 9.76 ENSRNOT00000003840
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr3_+_60024013 9.54 ENSRNOT00000025255
Scrn3
secernin 3
chr9_+_94702129 8.86 ENSRNOT00000080930
Neu2
neuraminidase 2
chr2_+_200603426 7.81 ENSRNOT00000072189
LOC102550892
zinc finger protein 697-like
chr18_+_30004565 7.69 ENSRNOT00000027393
Pcdha4
protocadherin alpha 4
chr3_-_173944396 7.46 ENSRNOT00000079019
Sycp2
synaptonemal complex protein 2
chr3_-_160038078 7.34 ENSRNOT00000013445
Serinc3
serine incorporator 3
chr14_-_8432195 7.29 ENSRNOT00000089800
Arhgap24
Rho GTPase activating protein 24
chr12_-_13998172 6.89 ENSRNOT00000001476
Wipi2
WD repeat domain, phosphoinositide interacting 2
chr15_+_39779648 5.86 ENSRNOT00000084505
Cab39l
calcium binding protein 39-like
chr8_+_99568958 5.84 ENSRNOT00000073400
Plscr5
phospholipid scramblase family, member 5
chr10_+_72909550 5.61 ENSRNOT00000004540
Ppm1d
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr9_-_65790347 5.31 ENSRNOT00000028506
AABR07067812.1

chr6_+_122603269 5.29 ENSRNOT00000005297
Spata7
spermatogenesis associated 7
chrX_+_65040775 5.22 ENSRNOT00000081354
Zc3h12b
zinc finger CCCH-type containing 12B
chr13_-_98480419 4.88 ENSRNOT00000086306
Coq8a
coenzyme Q8A
chr7_-_57816621 4.77 ENSRNOT00000090748
AABR07057150.1

chr1_+_214562897 4.60 ENSRNOT00000085125
Ap2a2
adaptor-related protein complex 2, alpha 2 subunit
chr18_+_13386133 4.55 ENSRNOT00000020661
Asxl3
additional sex combs like 3, transcriptional regulator
chrX_+_65040934 4.15 ENSRNOT00000044006
Zc3h12b
zinc finger CCCH-type containing 12B
chr7_+_28654733 4.13 ENSRNOT00000006174
Pmch
pro-melanin-concentrating hormone
chr7_-_107775712 3.77 ENSRNOT00000010811
ENSRNOT00000093459
Ndrg1
N-myc downstream regulated 1
chr13_-_97838228 3.65 ENSRNOT00000003618
Tfb2m
transcription factor B2, mitochondrial
chr8_+_5522739 3.59 ENSRNOT00000011507
Mmp13
matrix metallopeptidase 13
chr14_-_6793558 3.38 ENSRNOT00000002927
Mepe
matrix extracellular phosphoglycoprotein
chr14_-_21810314 3.35 ENSRNOT00000002671
Csn3
casein kappa
chr10_+_105796680 3.18 ENSRNOT00000000264
Mfsd11
major facilitator superfamily domain containing 11
chr3_+_126335863 3.02 ENSRNOT00000028904
Bmp2
bone morphogenetic protein 2
chr11_+_69739384 2.95 ENSRNOT00000016340
Kalrn
kalirin, RhoGEF kinase
chr6_+_108167716 2.75 ENSRNOT00000064426
Lin52
lin-52 DREAM MuvB core complex component
chr9_+_111249351 2.52 ENSRNOT00000076729
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr5_+_50075527 2.38 ENSRNOT00000011688
Rars2
arginyl-tRNA synthetase 2, mitochondrial
chr1_+_190671696 2.28 ENSRNOT00000084934
AABR07005633.1

chr18_+_68408890 2.03 ENSRNOT00000039702
Ccdc68
coiled-coil domain containing 68
chr10_+_11393103 1.91 ENSRNOT00000076022
Adcy9
adenylate cyclase 9
chr6_+_91595823 1.90 ENSRNOT00000006223
Klhdc2
kelch domain containing 2
chr1_-_214455039 1.40 ENSRNOT00000071028
Polr2l
RNA polymerase II subunit L
chrX_+_83926513 1.24 ENSRNOT00000035274
RGD1561958
similar to RIKEN cDNA 2010106E10
chr20_-_11721838 1.16 ENSRNOT00000001636
Ube2g2
ubiquitin-conjugating enzyme E2G 2
chr17_+_86408151 0.99 ENSRNOT00000022734
Otud1
OTU deubiquitinase 1
chr14_-_3351553 0.96 ENSRNOT00000061556
Btbd8
BTB (POZ) domain containing 8
chr1_-_102970950 0.72 ENSRNOT00000018194
Tsg101
tumor susceptibility 101
chr2_+_193724248 0.51 ENSRNOT00000025249
Rptn
repetin
chr3_+_137154086 0.41 ENSRNOT00000034252
Otor
otoraplin
chr6_-_109095557 0.24 ENSRNOT00000033493
Mlh3
mutL homolog 3
chr4_+_71512695 0.11 ENSRNOT00000037220
Tas2r139
taste receptor, type 2, member 139

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxf2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
18.8 56.4 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) diacylglycerol catabolic process(GO:0046340)
10.9 32.6 GO:1990743 protein sialylation(GO:1990743)
7.4 44.5 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
6.5 32.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
6.0 35.9 GO:0001705 ectoderm formation(GO:0001705)
5.4 32.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
4.8 14.4 GO:0006574 valine catabolic process(GO:0006574)
4.7 23.3 GO:0009826 unidimensional cell growth(GO:0009826)
4.4 35.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
4.1 12.4 GO:0018094 protein polyglycylation(GO:0018094)
3.9 15.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.8 15.1 GO:0072318 clathrin coat disassembly(GO:0072318)
3.7 14.8 GO:0009992 cellular water homeostasis(GO:0009992)
3.3 9.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
2.9 32.1 GO:0097264 self proteolysis(GO:0097264)
2.7 29.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.2 8.9 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692)
2.0 25.8 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
1.9 20.7 GO:0070327 thyroid hormone transport(GO:0070327)
1.8 7.3 GO:0009597 detection of virus(GO:0009597)
1.6 11.4 GO:0000103 sulfate assimilation(GO:0000103)
1.5 11.9 GO:0070842 aggresome assembly(GO:0070842)
1.3 14.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
1.2 7.5 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
1.0 4.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.0 3.0 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) embryonic heart tube anterior/posterior pattern specification(GO:0035054) corticotropin hormone secreting cell differentiation(GO:0060128)
0.9 16.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.8 29.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.7 7.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.7 26.2 GO:0017144 drug metabolic process(GO:0017144)
0.7 3.6 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.7 5.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.6 2.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.6 2.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125) NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.6 13.9 GO:0035864 response to potassium ion(GO:0035864)
0.5 11.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.5 12.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 3.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.4 5.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 5.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.3 4.9 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 3.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.7 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 6.9 GO:0097352 autophagosome maturation(GO:0097352)
0.2 10.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 3.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 13.2 GO:0042246 tissue regeneration(GO:0042246)
0.1 43.6 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.1 2.5 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.9 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 1.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 21.0 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 28.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 3.3 GO:0007595 lactation(GO:0007595)
0.1 7.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 56.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
4.3 29.9 GO:0005579 membrane attack complex(GO:0005579)
4.1 32.6 GO:0005577 fibrinogen complex(GO:0005577)
1.5 23.3 GO:0070852 cell body fiber(GO:0070852)
1.2 35.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 32.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.6 11.2 GO:0071437 invadopodium(GO:0071437)
0.5 6.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 30.0 GO:0005581 collagen trimer(GO:0005581)
0.4 2.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.4 20.7 GO:0031526 brush border membrane(GO:0031526)
0.4 12.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 7.5 GO:0000800 lateral element(GO:0000800)
0.3 4.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 3.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 10.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 17.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 10.0 GO:0016459 myosin complex(GO:0016459)
0.1 48.9 GO:0014069 postsynaptic density(GO:0014069)
0.1 3.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 16.6 GO:0030027 lamellipodium(GO:0030027)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.2 GO:0005712 chiasma(GO:0005712)
0.1 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 23.1 GO:0043235 receptor complex(GO:0043235)
0.1 3.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 52.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 11.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 39.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 5.6 GO:0030426 growth cone(GO:0030426)
0.0 7.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
18.8 56.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
14.8 44.5 GO:0070012 oligopeptidase activity(GO:0070012)
10.9 32.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
5.0 35.0 GO:0097001 ceramide binding(GO:0097001)
4.1 12.4 GO:0070735 protein-glycine ligase activity(GO:0070735)
3.8 11.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
2.7 33.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
2.6 20.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.5 14.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
2.2 8.9 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
2.2 26.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
2.0 12.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.8 10.9 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.5 30.0 GO:0005537 mannose binding(GO:0005537)
1.2 3.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.0 25.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.9 11.9 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.7 9.5 GO:0016805 dipeptidase activity(GO:0016805)
0.7 32.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.6 2.5 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
0.6 7.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 2.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.5 14.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.5 6.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 3.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 10.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 16.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 3.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.3 30.0 GO:0051087 chaperone binding(GO:0051087)
0.3 21.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3 5.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 15.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 18.3 GO:0038024 cargo receptor activity(GO:0038024)
0.2 45.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 35.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 3.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 4.9 GO:0043531 ADP binding(GO:0043531)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 1.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 10.0 GO:0003774 motor activity(GO:0003774)
0.0 4.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 4.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 26.6 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 77.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.7 10.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.4 55.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 16.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 2.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 5.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 77.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
3.3 56.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
2.4 9.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
2.1 20.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.9 32.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.7 25.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.4 38.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.9 29.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.9 11.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.8 23.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.8 14.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 14.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6 15.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.5 26.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.4 10.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.4 5.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.4 4.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 8.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 3.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 21.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 31.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 7.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 3.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 10.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.7 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 4.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events