ISMARA results: Foxp2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Foxp2_Foxp3

Z-value: 0.86

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Transcription factors associated with Foxp2_Foxp3

Gene Symbol	Gene ID	Gene Info
Foxp2 NCBI RGD Ensembl	ENSRNOG00000054508	forkhead box P2
Foxp3 NCBI RGD Ensembl	ENSRNOG00000011702	forkhead box P3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Foxp3	rn6_v1_chrX_-_15761932_15761932	0.28	4.7e-07	Click!
Foxp2	rn6_v1_chr4_+_41364441_41364441	0.23	4.4e-05	Click!

Activity profile of Foxp2_Foxp3 motif

Sorted Z-values of Foxp2_Foxp3 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_103395511 Show fit	26.13	ENSRNOT00000004256	Gprc5c NCBI RGD Ensembl Show fit	G protein-coupled receptor, class C, group 5, member C
chr10_+_96639924 Show fit	21.80	ENSRNOT00000004756	Apoh NCBI RGD Ensembl Show fit	apolipoprotein H
chr4_-_30556814 Show fit	20.82	ENSRNOT00000012760	Pdk4 NCBI RGD Ensembl Show fit	pyruvate dehydrogenase kinase 4
chr4_-_82289672 Show fit	19.96	ENSRNOT00000036394	Hoxa10 NCBI RGD Ensembl Show fit	homeobox A10
chr7_+_58814805 Show fit	19.87	ENSRNOT00000005909	Tspan8 NCBI RGD Ensembl Show fit	tetraspanin 8
chr7_+_74047814 Show fit	19.12	ENSRNOT00000014879	Osr2 NCBI RGD Ensembl Show fit	odd-skipped related transciption factor 2
chr6_+_129399468 Show fit	17.77	ENSRNOT00000071735 ENSRNOT00000074621	Bdkrb2 NCBI RGD Ensembl Show fit	bradykinin receptor B2
chr4_-_82295470 Show fit	17.48	ENSRNOT00000091073	Hoxa10 NCBI RGD Ensembl Show fit	homeobox A10
chr5_+_124300477 Show fit	16.85	ENSRNOT00000010100	C8b NCBI RGD Ensembl Show fit	complement C8 beta chain
chr4_-_82209933 Show fit	16.85	ENSRNOT00000091106	LOC100912608 NCBI RGD Ensembl Show fit	homeobox protein Hox-A10-like
chr14_-_19072677 Show fit	16.79	ENSRNOT00000060548	LOC360919 NCBI RGD Ensembl Show fit	similar to alpha-fetoprotein
chr5_-_88629491 Show fit	14.69	ENSRNOT00000058906	Tle1 NCBI RGD Ensembl Show fit	transducin like enhancer of split 1
chr4_+_169147243 Show fit	14.68	ENSRNOT00000011580	Emp1 NCBI RGD Ensembl Show fit	epithelial membrane protein 1
chr2_-_233743866 Show fit	13.86	ENSRNOT00000087062	Enpep NCBI RGD Ensembl Show fit	glutamyl aminopeptidase
chr5_+_152533349 Show fit	13.54	ENSRNOT00000067524	Trim63 NCBI RGD Ensembl Show fit	tripartite motif containing 63
chr4_-_115239723 Show fit	13.37	ENSRNOT00000042699	Actg2 NCBI RGD Ensembl Show fit	actin, gamma 2, smooth muscle, enteric
chr6_-_108167185 Show fit	13.16	ENSRNOT00000015545	Aldh6a1 NCBI RGD Ensembl Show fit	aldehyde dehydrogenase 6 family, member A1
chr4_+_169161585 Show fit	12.92	ENSRNOT00000079785	Emp1 NCBI RGD Ensembl Show fit	epithelial membrane protein 1
chr20_-_54517709 Show fit	12.68	ENSRNOT00000076234	Grik2 NCBI RGD Ensembl Show fit	glutamate ionotropic receptor kainate type subunit 2
chr15_-_28313841 Show fit	12.10	ENSRNOT00000085897	Ndrg2 NCBI RGD Ensembl Show fit	NDRG family member 2
chr13_-_98480419 Show fit	12.10	ENSRNOT00000086306	Coq8a NCBI RGD Ensembl Show fit	coenzyme Q8A
chr8_-_49109981 Show fit	11.89	ENSRNOT00000019933	Ttc36 NCBI RGD Ensembl Show fit	tetratricopeptide repeat domain 36
chr5_-_101166651 Show fit	11.83	ENSRNOT00000078862	Frem1 NCBI RGD Ensembl Show fit	Fras1 related extracellular matrix 1
chr10_+_56662242 Show fit	11.63	ENSRNOT00000086919	Asgr1 NCBI RGD Ensembl Show fit	asialoglycoprotein receptor 1
chr13_-_1946508 Show fit	11.47	ENSRNOT00000043890	Dsel NCBI RGD Ensembl Show fit	dermatan sulfate epimerase-like
chr1_+_225184939 Show fit	11.24	ENSRNOT00000079456	Ahnak NCBI RGD Ensembl Show fit	AHNAK nucleoprotein
chr7_-_29171783 Show fit	10.90	ENSRNOT00000079235	Mybpc1 NCBI RGD Ensembl Show fit	myosin binding protein C, slow type
chr7_+_144577465 Show fit	10.87	ENSRNOT00000021647	Hoxc10 NCBI RGD Ensembl Show fit	homeo box C10
chr2_-_204254699 Show fit	10.74	ENSRNOT00000021487	Mab21l3 NCBI RGD Ensembl Show fit	mab-21 like 3
chr4_+_83713666 Show fit	10.54	ENSRNOT00000086473	Creb5 NCBI RGD Ensembl Show fit	cAMP responsive element binding protein 5
chr7_-_97605113 Show fit	10.31	ENSRNOT00000089734	AABR07058000.1 NCBI RGD Ensembl Show fit
chr7_-_138483612 Show fit	10.27	ENSRNOT00000085620	Slc38a4 NCBI RGD Ensembl Show fit	solute carrier family 38, member 4
chr5_+_25349928 Show fit	10.21	ENSRNOT00000020826	Gem NCBI RGD Ensembl Show fit	GTP binding protein overexpressed in skeletal muscle
chrX_-_111887906 Show fit	10.06	ENSRNOT00000085118	Tsc22d3 NCBI RGD Ensembl Show fit	TSC22 domain family, member 3
chr1_-_267203986 Show fit	9.95	ENSRNOT00000027574	Sh3pxd2a NCBI RGD Ensembl Show fit	SH3 and PX domains 2A
chr2_-_98610368 Show fit	9.69	ENSRNOT00000011641	Zfhx4 NCBI RGD Ensembl Show fit	zinc finger homeobox 4
chr12_+_9446940 Show fit	9.44	ENSRNOT00000074791	Urad NCBI RGD Ensembl Show fit	ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr10_-_74298599 Show fit	9.39	ENSRNOT00000007379	Ypel2 NCBI RGD Ensembl Show fit	yippee-like 2
chr1_+_250426158 Show fit	9.29	ENSRNOT00000067643	A1cf NCBI RGD Ensembl Show fit	APOBEC1 complementation factor
chr18_+_3887419 Show fit	9.28	ENSRNOT00000093089	Lama3 NCBI RGD Ensembl Show fit	laminin subunit alpha 3
chr2_-_53300404 Show fit	9.24	ENSRNOT00000088876	Ghr NCBI RGD Ensembl Show fit	growth hormone receptor
chr4_+_154309426 Show fit	9.18	ENSRNOT00000019346	A2m NCBI RGD Ensembl Show fit	alpha-2-macroglobulin
chr18_+_29352749 Show fit	8.86	ENSRNOT00000025137	Slc4a9 NCBI RGD Ensembl Show fit	solute carrier family 4 member 9
chr7_-_119689938 Show fit	8.81	ENSRNOT00000000200	Tmprss6 NCBI RGD Ensembl Show fit	transmembrane protease, serine 6
chr17_+_12310214 Show fit	8.79	ENSRNOT00000015786	Auh NCBI RGD Ensembl Show fit	AU RNA binding methylglutaconyl-CoA hydratase
chr7_+_99954492 Show fit	8.72	ENSRNOT00000005885	Trib1 NCBI RGD Ensembl Show fit	tribbles pseudokinase 1
chr17_+_32973695 Show fit	8.63	ENSRNOT00000065674	RGD1565323 NCBI RGD Ensembl Show fit	similar to OTTMUSP00000000621
chr10_+_11393103 Show fit	8.44	ENSRNOT00000076022	Adcy9 NCBI RGD Ensembl Show fit	adenylate cyclase 9
chr8_-_104593625 Show fit	8.41	ENSRNOT00000016625	Zbtb38 NCBI RGD Ensembl Show fit	zinc finger and BTB domain containing 38
chr6_-_127534247 Show fit	8.38	ENSRNOT00000012500	Serpina6 NCBI RGD Ensembl Show fit	serpin family A member 6
chr4_+_62380914 Show fit	8.37	ENSRNOT00000029845	Tmem140 NCBI RGD Ensembl Show fit	transmembrane protein 140
chr10_+_56824505 Show fit	8.20	ENSRNOT00000067128	Slc16a11 NCBI RGD Ensembl Show fit	solute carrier family 16, member 11
chr9_+_43093138 Show fit	7.99	ENSRNOT00000021592	Cnnm3 NCBI RGD Ensembl Show fit	cyclin and CBS domain divalent metal cation transport mediator 3
chr1_-_48360131 Show fit	7.96	ENSRNOT00000051927 ENSRNOT00000023116	Slc22a2 NCBI RGD Ensembl Show fit	solute carrier family 22 member 2
chr8_+_65733400 Show fit	7.93	ENSRNOT00000089126	Uaca NCBI RGD Ensembl Show fit	uveal autoantigen with coiled-coil domains and ankyrin repeats
chrX_+_15669191 Show fit	7.92	ENSRNOT00000013553	Magix NCBI RGD Ensembl Show fit	MAGI family member, X-linked
chr15_+_34216833 Show fit	7.83	ENSRNOT00000025260	Pck2 NCBI RGD Ensembl Show fit	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr4_+_44774741 Show fit	7.74	ENSRNOT00000086902	Met NCBI RGD Ensembl Show fit	MET proto-oncogene, receptor tyrosine kinase
chr12_-_1816414 Show fit	7.70	ENSRNOT00000041155 ENSRNOT00000067448	Insr NCBI RGD Ensembl Show fit	insulin receptor
chr1_-_131460473 Show fit	7.60	ENSRNOT00000084336	Nr2f2 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 2, group F, member 2
chr18_+_61258911 Show fit	7.38	ENSRNOT00000082403	Zfp532 NCBI RGD Ensembl Show fit	zinc finger protein 532
chr1_-_31055453 Show fit	7.36	ENSRNOT00000031083	Soga3 NCBI RGD Ensembl Show fit	SOGA family member 3
chr3_+_126335863 Show fit	7.36	ENSRNOT00000028904	Bmp2 NCBI RGD Ensembl Show fit	bone morphogenetic protein 2
chr1_+_220114228 Show fit	7.33	ENSRNOT00000026718	Ctsf NCBI RGD Ensembl Show fit	cathepsin F
chr15_-_37983882 Show fit	7.28	ENSRNOT00000087978	Lats2 NCBI RGD Ensembl Show fit	large tumor suppressor kinase 2
chrX_+_119390013 Show fit	7.20	ENSRNOT00000074269	Agtr2 NCBI RGD Ensembl Show fit	angiotensin II receptor, type 2
chr14_-_60964324 Show fit	7.17	ENSRNOT00000005155	Sod3 NCBI RGD Ensembl Show fit	superoxide dismutase 3, extracellular
chr11_-_61475681 Show fit	7.15	ENSRNOT00000093249	Usf3 NCBI RGD Ensembl Show fit	upstream transcription factor family member 3
chr9_-_52238564 Show fit	7.12	ENSRNOT00000005073	Col5a2 NCBI RGD Ensembl Show fit	collagen type V alpha 2 chain
chr3_+_11114551 Show fit	7.07	ENSRNOT00000013507	Plpp7 NCBI RGD Ensembl Show fit	phospholipid phosphatase 7
chr1_+_100845563 Show fit	7.03	ENSRNOT00000027478	Akt1s1 NCBI RGD Ensembl Show fit	AKT1 substrate 1
chr3_+_101791337 Show fit	6.99	ENSRNOT00000046937	Slc5a12 NCBI RGD Ensembl Show fit	solute carrier family 5 member 12
chr3_-_57957346 Show fit	6.88	ENSRNOT00000036728	Slc25a12 NCBI RGD Ensembl Show fit	solute carrier family 25 member 12
chr18_+_65155685 Show fit	6.69	ENSRNOT00000081797	Tcf4 NCBI RGD Ensembl Show fit	transcription factor 4
chr1_+_243375981 Show fit	6.65	ENSRNOT00000080689	Kank1 NCBI RGD Ensembl Show fit	KN motif and ankyrin repeat domains 1
chr11_-_45124423 Show fit	6.55	ENSRNOT00000046383	Filip1l NCBI RGD Ensembl Show fit	filamin A interacting protein 1-like
chr15_+_34234755 Show fit	6.54	ENSRNOT00000059987	Dcaf11 NCBI RGD Ensembl Show fit	DDB1 and CUL4 associated factor 11
chr8_+_50559126 Show fit	6.52	ENSRNOT00000024918	Apoa5 NCBI RGD Ensembl Show fit	apolipoprotein A5
chr7_+_3900228 Show fit	6.46	ENSRNOT00000071350	Olr921 NCBI RGD Ensembl Show fit	olfactory receptor 921
chr4_+_115416580 Show fit	6.43	ENSRNOT00000018303	Atp6v1b1 NCBI RGD Ensembl Show fit	ATPase H+ transporting V1 subunit B1
chr2_+_185393441 Show fit	6.42	ENSRNOT00000015802	Sh3d19 NCBI RGD Ensembl Show fit	SH3 domain containing 19
chr8_-_50245838 Show fit	6.34	ENSRNOT00000035310	Sidt2 NCBI RGD Ensembl Show fit	SID1 transmembrane family, member 2
chr13_+_50103189 Show fit	6.31	ENSRNOT00000004078	Atp2b4 NCBI RGD Ensembl Show fit	ATPase plasma membrane Ca2+ transporting 4
chr8_+_57886168 Show fit	6.31	ENSRNOT00000039336	Exph5 NCBI RGD Ensembl Show fit	exophilin 5
chr7_+_143749221 Show fit	6.27	ENSRNOT00000014807	Igfbp6 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 6
chr4_+_83391283 Show fit	6.27	ENSRNOT00000031365	Creb5 NCBI RGD Ensembl Show fit	cAMP responsive element binding protein 5
chr5_-_124403195 Show fit	6.12	ENSRNOT00000067850	C8a NCBI RGD Ensembl Show fit	complement C8 alpha chain
chr3_-_72219246 Show fit	6.01	ENSRNOT00000009903	Smtnl1 NCBI RGD Ensembl Show fit	smoothelin-like 1
chr19_-_52206310 Show fit	6.01	ENSRNOT00000087886	Mbtps1 NCBI RGD Ensembl Show fit	membrane-bound transcription factor peptidase, site 1
chr1_+_260798239 Show fit	6.01	ENSRNOT00000036791	Lcor NCBI RGD Ensembl Show fit	ligand dependent nuclear receptor corepressor
chr15_+_24942218 Show fit	5.93	ENSRNOT00000016629	Peli2 NCBI RGD Ensembl Show fit	pellino E3 ubiquitin protein ligase family member 2
chr13_+_80125391 Show fit	5.92	ENSRNOT00000044190	Mir199a2 NCBI RGD Ensembl Show fit	microRNA 199a-2
chr1_+_107344904 Show fit	5.84	ENSRNOT00000082582	Gas2 NCBI RGD Ensembl Show fit	growth arrest-specific 2
chr4_+_41364441 Show fit	5.84	ENSRNOT00000087146	Foxp2 NCBI RGD Ensembl Show fit	forkhead box P2
chr10_-_87500919 Show fit	5.83	ENSRNOT00000084798	Krtap1-5 NCBI RGD Ensembl Show fit	keratin associated protein 1-5
chr14_-_66978499 Show fit	5.78	ENSRNOT00000081601	Slit2 NCBI RGD Ensembl Show fit	slit guidance ligand 2
chr9_+_74124016 Show fit	5.76	ENSRNOT00000019023	Cps1 NCBI RGD Ensembl Show fit	carbamoyl-phosphate synthase 1
chr17_-_22143324 Show fit	5.73	ENSRNOT00000019361	Edn1 NCBI RGD Ensembl Show fit	endothelin 1
chr5_+_162808646 Show fit	5.69	ENSRNOT00000021155	Dhrs3 NCBI RGD Ensembl Show fit	dehydrogenase/reductase 3
chr10_+_98706960 Show fit	5.69	ENSRNOT00000006217	Map2k6 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase 6
chr3_+_72460889 Show fit	5.67	ENSRNOT00000012209	Tnks1bp1 NCBI RGD Ensembl Show fit	tankyrase 1 binding protein 1
chr6_+_1147012 Show fit	5.58	ENSRNOT00000006360	Vit NCBI RGD Ensembl Show fit	vitrin
chr10_+_56662561 Show fit	5.58	ENSRNOT00000025254	Asgr1 NCBI RGD Ensembl Show fit	asialoglycoprotein receptor 1
chr4_+_62221011 Show fit	5.54	ENSRNOT00000041264	Cald1 NCBI RGD Ensembl Show fit	caldesmon 1
chr8_-_50246656 Show fit	5.51	ENSRNOT00000024240	Sidt2 NCBI RGD Ensembl Show fit	SID1 transmembrane family, member 2
chr5_-_28131133 Show fit	5.37	ENSRNOT00000067331	Slc26a7 NCBI RGD Ensembl Show fit	solute carrier family 26 member 7
chr5_-_60559533 Show fit	5.36	ENSRNOT00000092899	Zbtb5 NCBI RGD Ensembl Show fit	zinc finger and BTB domain containing 5
chr4_+_139670092 Show fit	5.33	ENSRNOT00000008879	Lrrn1 NCBI RGD Ensembl Show fit	leucine rich repeat neuronal 1
chrX_-_15627235 Show fit	5.31	ENSRNOT00000013369	Wdr45 NCBI RGD Ensembl Show fit	WD repeat domain 45
chr9_+_64745051 Show fit	5.30	ENSRNOT00000021527	Spats2l NCBI RGD Ensembl Show fit	spermatogenesis associated, serine-rich 2-like
chr2_-_198016898 Show fit	5.27	ENSRNOT00000025523	Car14 NCBI RGD Ensembl Show fit	carbonic anhydrase 14
chr2_+_222021103 Show fit	5.21	ENSRNOT00000086125	Dpyd NCBI RGD Ensembl Show fit	dihydropyrimidine dehydrogenase
chr2_+_155718359 Show fit	5.19	ENSRNOT00000077973	Kcnab1 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr5_-_33892462 Show fit	5.19	ENSRNOT00000009334	Atp6v0d2 NCBI RGD Ensembl Show fit	ATPase H+ transporting V0 subunit D2
chr2_+_198683159 Show fit	5.15	ENSRNOT00000028793	Txnip NCBI RGD Ensembl Show fit	thioredoxin interacting protein
chr1_-_236900904 Show fit	5.15	ENSRNOT00000066846	AABR07006480.1 NCBI RGD Ensembl Show fit
chr4_+_62220736 Show fit	5.13	ENSRNOT00000086377	Cald1 NCBI RGD Ensembl Show fit	caldesmon 1
chr1_+_141218095 Show fit	5.04	ENSRNOT00000051411	LOC691427 NCBI RGD Ensembl Show fit	similar to 6.8 kDa mitochondrial proteolipid
chr10_-_40296470 Show fit	5.03	ENSRNOT00000086456	Tnip1 NCBI RGD Ensembl Show fit	TNFAIP3 interacting protein 1
chrX_-_25590048 Show fit	5.01	ENSRNOT00000004873	Mid1 NCBI RGD Ensembl Show fit	midline 1
chr1_-_206282575 Show fit	5.00	ENSRNOT00000024974	Adam12 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 12
chr1_+_221236773 Show fit	4.96	ENSRNOT00000051979	Slc25a45 NCBI RGD Ensembl Show fit	solute carrier family 25, member 45
chr15_+_34552410 Show fit	4.96	ENSRNOT00000027802	Khnyn NCBI RGD Ensembl Show fit	KH and NYN domain containing
chr20_+_18780605 Show fit	4.89	ENSRNOT00000000754	Bicc1 NCBI RGD Ensembl Show fit	BicC family RNA binding protein 1
chr2_-_187909394 Show fit	4.81	ENSRNOT00000032355	Rab25 NCBI RGD Ensembl Show fit	RAB25, member RAS oncogene family
chrX_+_65566047 Show fit	4.74	ENSRNOT00000092103	Heph NCBI RGD Ensembl Show fit	hephaestin
chr4_-_170860225 Show fit	4.71	ENSRNOT00000007577	Mgp NCBI RGD Ensembl Show fit	matrix Gla protein
chr6_+_12362813 Show fit	4.71	ENSRNOT00000022370	Ston1 NCBI RGD Ensembl Show fit	stonin 1
chr6_+_43234526 Show fit	4.68	ENSRNOT00000086808	Asap2 NCBI RGD Ensembl Show fit	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr18_+_16146447 Show fit	4.66	ENSRNOT00000022117	Galnt1 NCBI RGD Ensembl Show fit	polypeptide N-acetylgalactosaminyltransferase 1
chr1_-_263762785 Show fit	4.61	ENSRNOT00000018221	Cpn1 NCBI RGD Ensembl Show fit	carboxypeptidase N subunit 1
chrX_+_157759624 Show fit	4.52	ENSRNOT00000003192	LOC686087 NCBI RGD Ensembl Show fit	similar to motile sperm domain containing 1
chr8_-_125645898 Show fit	4.49	ENSRNOT00000036672	Rbms3 NCBI RGD Ensembl Show fit	RNA binding motif, single stranded interacting protein 3
chr7_+_141053876 Show fit	4.48	ENSRNOT00000084674	Tmbim6 NCBI RGD Ensembl Show fit	transmembrane BAX inhibitor motif containing 6
chrM_-_14061 Show fit	4.40	ENSRNOT00000051268	Mt-nd6 NCBI RGD Ensembl Show fit	mitochondrially encoded NADH dehydrogenase 6
chr18_+_867048 Show fit	4.39	ENSRNOT00000065494	Colec12 NCBI RGD Ensembl Show fit	collectin sub-family member 12
chr1_+_240908483 Show fit	4.37	ENSRNOT00000019367	Klf9 NCBI RGD Ensembl Show fit	Kruppel-like factor 9
chr15_-_33051129 Show fit	4.36	ENSRNOT00000014391	Slc7a7 NCBI RGD Ensembl Show fit	solute carrier family 7 member 7
chr10_-_78155999 Show fit	4.35	ENSRNOT00000092852	Stxbp4 NCBI RGD Ensembl Show fit	syntaxin binding protein 4
chr3_+_117421604 Show fit	4.35	ENSRNOT00000008860 ENSRNOT00000008857	Slc12a1 NCBI RGD Ensembl Show fit	solute carrier family 12 member 1
chr13_-_80775230 Show fit	4.33	ENSRNOT00000091389 ENSRNOT00000004762	Fmo2 NCBI RGD Ensembl Show fit	flavin containing monooxygenase 2
chr1_+_243662823 Show fit	4.33	ENSRNOT00000067372	Dmrt2 NCBI RGD Ensembl Show fit	doublesex and mab-3 related transcription factor 2
chr1_-_252550394 Show fit	4.31	ENSRNOT00000083468	Acta2 NCBI RGD Ensembl Show fit	actin, alpha 2, smooth muscle, aorta
chr7_-_144269486 Show fit	4.29	ENSRNOT00000090051	Atp5g2 NCBI RGD Ensembl Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chrX_+_78042859 Show fit	4.28	ENSRNOT00000003286	Lpar4 NCBI RGD Ensembl Show fit	lysophosphatidic acid receptor 4
chr6_-_122721496 Show fit	4.28	ENSRNOT00000079697	Ptpn21 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, non-receptor type 21
chr13_+_89597138 Show fit	4.23	ENSRNOT00000004662	Apoa2 NCBI RGD Ensembl Show fit	apolipoprotein A2
chr5_+_48374096 Show fit	4.23	ENSRNOT00000010172	Gabrr1 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor rho 1 subunit
chr3_-_161299024 Show fit	4.15	ENSRNOT00000021216	Neurl2 NCBI RGD Ensembl Show fit	neuralized E3 ubiquitin protein ligase 2
chr2_-_192671059 Show fit	4.13	ENSRNOT00000012174	Sprr1a NCBI RGD Ensembl Show fit	small proline-rich protein 1A
chr17_-_15519060 Show fit	4.10	ENSRNOT00000093624	Aspnl1 NCBI RGD Ensembl Show fit	asporin-like 1
chr1_-_100845392 Show fit	4.06	ENSRNOT00000027436	Tbc1d17 NCBI RGD Ensembl Show fit	TBC1 domain family, member 17
chr3_-_119330345 Show fit	4.04	ENSRNOT00000077398 ENSRNOT00000079191	Trpm7 NCBI RGD Ensembl Show fit	transient receptor potential cation channel, subfamily M, member 7
chr2_+_209161047 Show fit	4.00	ENSRNOT00000023903	Dram2 NCBI RGD Ensembl Show fit	DNA-damage regulated autophagy modulator 2
chrX_+_111122552 Show fit	4.00	ENSRNOT00000083566 ENSRNOT00000085078 ENSRNOT00000090928	Cldn2 NCBI RGD Ensembl Show fit	claudin 2
chr15_+_59678165 Show fit	3.99	ENSRNOT00000074868	Enox1 NCBI RGD Ensembl Show fit	ecto-NOX disulfide-thiol exchanger 1
chr9_-_38196273 Show fit	3.98	ENSRNOT00000044452	Dst NCBI RGD Ensembl Show fit	dystonin
chr15_+_55126953 Show fit	3.96	ENSRNOT00000021430	Lpar6 NCBI RGD Ensembl Show fit	lysophosphatidic acid receptor 6
chr8_+_85417838 Show fit	3.92	ENSRNOT00000012257	Ick NCBI RGD Ensembl Show fit	intestinal cell kinase
chr1_+_68436593 Show fit	3.89	ENSRNOT00000080325	LOC108348118 NCBI RGD Ensembl Show fit	leucyl-cystinyl aminopeptidase
chrX_-_118513061 Show fit	3.89	ENSRNOT00000043338	Il13ra2 NCBI RGD Ensembl Show fit	interleukin 13 receptor subunit alpha 2
chr4_+_154423209 Show fit	3.88	ENSRNOT00000075799	LOC100911545 NCBI RGD Ensembl Show fit	alpha-2-macroglobulin-like
chr11_-_32550539 Show fit	3.88	ENSRNOT00000002715	Rcan1 NCBI RGD Ensembl Show fit	regulator of calcineurin 1
chrX_+_143097525 Show fit	3.87	ENSRNOT00000004559	F9 NCBI RGD Ensembl Show fit	coagulation factor IX
chr1_+_137014272 Show fit	3.85	ENSRNOT00000014802	Akap13 NCBI RGD Ensembl Show fit	A-kinase anchoring protein 13
chr3_-_2453933 Show fit	3.80	ENSRNOT00000014060	Slc34a3 NCBI RGD Ensembl Show fit	solute carrier family 34 member 3
chr1_+_100473643 Show fit	3.77	ENSRNOT00000026379	Josd2 NCBI RGD Ensembl Show fit	Josephin domain containing 2
chr1_-_277181345 Show fit	3.74	ENSRNOT00000038017 ENSRNOT00000038038	Nrap NCBI RGD Ensembl Show fit	nebulin-related anchoring protein
chr6_-_51257625 Show fit	3.73	ENSRNOT00000012004	Hbp1 NCBI RGD Ensembl Show fit	HMG-box transcription factor 1
chr1_+_83003841 Show fit	3.72	ENSRNOT00000057384	Ceacam4 NCBI RGD Ensembl Show fit	carcinoembryonic antigen-related cell adhesion molecule 4
chr1_-_275876329 Show fit	3.72	ENSRNOT00000047903	Gpam NCBI RGD Ensembl Show fit	glycerol-3-phosphate acyltransferase, mitochondrial
chr3_+_60024013 Show fit	3.71	ENSRNOT00000025255	Scrn3 NCBI RGD Ensembl Show fit	secernin 3
chr18_+_27558089 Show fit	3.69	ENSRNOT00000027499	Fam53c NCBI RGD Ensembl Show fit	family with sequence similarity 53, member C
chr1_+_247228061 Show fit	3.64	ENSRNOT00000020809	Rcl1 NCBI RGD Ensembl Show fit	RNA terminal phosphate cyclase-like 1
chr20_+_26893016 Show fit	3.64	ENSRNOT00000082430	Dnajc12 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C12
chr16_+_29674793 Show fit	3.62	ENSRNOT00000059724	Anxa10 NCBI RGD Ensembl Show fit	annexin A10
chr15_+_41937880 Show fit	3.62	ENSRNOT00000032514	Kcnrg NCBI RGD Ensembl Show fit	potassium channel regulator
chr15_-_9086282 Show fit	3.61	ENSRNOT00000008989	Thrb NCBI RGD Ensembl Show fit	thyroid hormone receptor beta
chr3_+_5519990 Show fit	3.60	ENSRNOT00000070873 ENSRNOT00000007640	Adamts13 NCBI RGD Ensembl Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr9_+_61720583 Show fit	3.58	ENSRNOT00000020536	Mob4 NCBI RGD Ensembl Show fit	MOB family member 4, phocein
chr1_-_127292090 Show fit	3.55	ENSRNOT00000016959	Lrrk1 NCBI RGD Ensembl Show fit	leucine-rich repeat kinase 1
chr7_+_59326518 Show fit	3.53	ENSRNOT00000085231	Ptprb NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type, B
chr15_+_34234193 Show fit	3.48	ENSRNOT00000077584	Dcaf11 NCBI RGD Ensembl Show fit	DDB1 and CUL4 associated factor 11
chr7_-_16036185 Show fit	3.47	ENSRNOT00000047899	LOC108348036 NCBI RGD Ensembl Show fit	olfactory receptor 6C2-like
chr4_-_15505362 Show fit	3.47	ENSRNOT00000009763	Hgf NCBI RGD Ensembl Show fit	hepatocyte growth factor
chr14_+_18983853 Show fit	3.43	ENSRNOT00000003836	Rassf6 NCBI RGD Ensembl Show fit	Ras association domain family member 6
chr11_+_74057361 Show fit	3.40	ENSRNOT00000048746	Cpn2 NCBI RGD Ensembl Show fit	carboxypeptidase N subunit 2
chr1_-_167700332 Show fit	3.39	ENSRNOT00000092890	Trim21 NCBI RGD Ensembl Show fit	tripartite motif-containing 21
chr17_-_21739408 Show fit	3.37	ENSRNOT00000060335	Gcnt2 NCBI RGD Ensembl Show fit	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_+_82419947 Show fit	3.36	ENSRNOT00000027964	B3gnt8 NCBI RGD Ensembl Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr13_-_97838228 Show fit	3.36	ENSRNOT00000003618	Tfb2m NCBI RGD Ensembl Show fit	transcription factor B2, mitochondrial
chr17_-_1093873 Show fit	3.28	ENSRNOT00000086130	Ptch1 NCBI RGD Ensembl Show fit	patched 1
chr14_-_72025137 Show fit	3.27	ENSRNOT00000080604	C1qtnf7 NCBI RGD Ensembl Show fit	C1q and tumor necrosis factor related protein 7
chr6_-_3355339 Show fit	3.24	ENSRNOT00000084602	Map4k3 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase kinase 3
chr7_+_93975451 Show fit	3.24	ENSRNOT00000011379	Colec10 NCBI RGD Ensembl Show fit	collectin subfamily member 10
chr10_-_102423084 Show fit	3.20	ENSRNOT00000065145	Sdk2 NCBI RGD Ensembl Show fit	sidekick cell adhesion molecule 2
chr2_+_85305225 Show fit	3.15	ENSRNOT00000015904	Tas2r119 NCBI RGD Ensembl Show fit	taste receptor, type 2, member 119
chr9_-_54327958 Show fit	3.15	ENSRNOT00000019465	Stat1 NCBI RGD Ensembl Show fit	signal transducer and activator of transcription 1
chr10_+_105393072 Show fit	3.14	ENSRNOT00000013359	Ubald2 NCBI RGD Ensembl Show fit	UBA-like domain containing 2
chr15_-_50425900 Show fit	3.13	ENSRNOT00000058715	Adam28 NCBI RGD Ensembl Show fit	ADAM metallopeptidase domain 28

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxp2_Foxp3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.4	19.1	GO:0036023	embryonic skeletal limb joint morphogenesis(GO:0036023)
5.5	21.8	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
5.4	16.2	GO:0006574	valine catabolic process(GO:0006574)
5.2	20.8	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
4.4	17.8	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
4.0	12.1	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.6	10.7	GO:0000821	regulation of arginine metabolic process(GO:0000821)
3.5	17.7	GO:0090131	mesenchyme migration(GO:0090131)
2.8	13.9	GO:0002003	angiotensin maturation(GO:0002003)
2.7	13.5	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.7	10.8	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
2.6	7.8	GO:0006116	NADH oxidation(GO:0006116)
2.5	7.6	GO:0060838	lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
2.5	7.4	GO:0060128	embryonic heart tube anterior/posterior pattern specification(GO:0035054) corticotropin hormone secreting cell differentiation(GO:0060128)
2.4	7.3	GO:0001827	inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
2.4	7.2	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018) G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) regulation of metanephros size(GO:0035566)
2.3	9.3	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) cytidine to uridine editing(GO:0016554)
2.3	9.2	GO:1990402	embryonic liver development(GO:1990402)
2.3	11.5	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
2.2	8.7	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
2.1	2.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
2.0	11.9	GO:0033227	dsRNA transport(GO:0033227)
1.9	7.7	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.9	5.8	GO:0071623	chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
1.9	5.7	GO:0031583	phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
1.8	7.1	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
1.7	5.2	GO:0046127	thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
1.7	6.9	GO:0089712	malate-aspartate shuttle(GO:0043490) L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
1.7	6.7	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
1.6	6.4	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
1.5	27.6	GO:0032060	bleb assembly(GO:0032060)
1.5	16.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
1.5	4.5	GO:1904721	negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.5	4.4	GO:0071387	cellular response to cortisol stimulus(GO:0071387)
1.4	4.3	GO:0032978	protein insertion into membrane from inner side(GO:0032978)
1.4	5.7	GO:0072709	cellular response to sorbitol(GO:0072709)
1.4	2.8	GO:0072185	metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
1.4	13.8	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
1.3	8.0	GO:0072675	osteoclast fusion(GO:0072675)
1.3	9.2	GO:0006600	creatine metabolic process(GO:0006600)
1.3	7.7	GO:0060267	positive regulation of respiratory burst(GO:0060267)
1.2	48.3	GO:0009954	proximal/distal pattern formation(GO:0009954)
1.2	10.9	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
1.2	5.8	GO:0071400	cellular response to oleic acid(GO:0071400)
1.1	4.4	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
1.1	3.3	GO:0021997	neural plate axis specification(GO:0021997)
1.1	4.3	GO:0072592	oxygen metabolic process(GO:0072592)
1.1	4.3	GO:0061055	myotome development(GO:0061055)
1.1	5.3	GO:0046725	negative regulation by virus of viral protein levels in host cell(GO:0046725)
1.0	3.1	GO:1904531	transitional stage B cell differentiation(GO:0002332) transitional one stage B cell differentiation(GO:0002333) glomerular visceral epithelial cell apoptotic process(GO:1903210) positive regulation of actin filament binding(GO:1904531) positive regulation of actin binding(GO:1904618)
1.0	8.0	GO:0015871	choline transport(GO:0015871)
1.0	3.0	GO:0036395	pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
1.0	5.0	GO:0000066	mitochondrial ornithine transport(GO:0000066)
1.0	16.8	GO:2000811	negative regulation of anoikis(GO:2000811)
1.0	3.9	GO:0035720	intraciliary anterograde transport(GO:0035720)
1.0	3.8	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.0	2.9	GO:0010813	neuropeptide catabolic process(GO:0010813)
0.9	4.7	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.9	2.8	GO:0071461	cellular response to redox state(GO:0071461)
0.9	4.6	GO:0030070	insulin processing(GO:0030070)
0.9	2.7	GO:0048014	Tie signaling pathway(GO:0048014)
0.9	2.6	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.9	3.5	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.9	4.3	GO:0002159	desmosome assembly(GO:0002159)
0.8	2.5	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.8	8.8	GO:0097264	self proteolysis(GO:0097264)
0.8	3.2	GO:0006272	leading strand elongation(GO:0006272)
0.8	3.1	GO:0098886	modification of dendritic spine(GO:0098886)
0.8	7.0	GO:0015727	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.8	12.1	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.8	3.0	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.7	5.8	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.7	5.7	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.7	12.6	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.7	13.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.7	2.1	GO:0097298	regulation of nucleus size(GO:0097298)
0.7	8.8	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.7	3.4	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.7	2.0	GO:1905244	negative regulation of long term synaptic depression(GO:1900453) regulation of intracellular transport of viral material(GO:1901252) regulation of modification of synaptic structure(GO:1905244)
0.7	4.0	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.7	3.4	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.7	5.9	GO:0008063	Toll signaling pathway(GO:0008063)
0.6	2.6	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.6	2.6	GO:0019046	viral latency(GO:0019042) release from viral latency(GO:0019046)
0.6	1.9	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.6	3.8	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.6	1.9	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.6	6.3	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.6	2.5	GO:0009992	cellular water homeostasis(GO:0009992)
0.6	3.6	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.6	3.6	GO:0008050	female courtship behavior(GO:0008050)
0.6	1.8	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6	11.8	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.6	2.3	GO:0032345	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.6	1.1	GO:1900135	positive regulation of renin secretion into blood stream(GO:1900135)
0.6	6.8	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.6	2.8	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.6	3.4	GO:0036438	maintenance of lens transparency(GO:0036438)
0.5	7.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.5	5.1	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.5	3.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.5	2.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.5	1.0	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.5	1.9	GO:0009441	glycolate metabolic process(GO:0009441)
0.5	4.3	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.5	6.7	GO:0042118	endothelial cell activation(GO:0042118)
0.5	2.3	GO:0060762	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.5	6.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.5	5.0	GO:0035372	protein localization to microtubule(GO:0035372)
0.4	8.4	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.4	1.8	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.4	3.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.4	3.9	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.4	1.7	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.4	1.2	GO:1900272	negative regulation of long-term synaptic potentiation(GO:1900272)
0.4	3.1	GO:0015679	plasma membrane copper ion transport(GO:0015679)
0.4	19.9	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.4	5.8	GO:0031167	rRNA methylation(GO:0031167)
0.4	1.5	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419) sequestering of BMP in extracellular matrix(GO:0035582)
0.4	2.3	GO:0031034	myosin filament assembly(GO:0031034)
0.4	1.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.4	7.8	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.4	1.5	GO:0070627	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4	2.9	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.4	2.1	GO:0036486	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.4	3.5	GO:0036035	osteoclast development(GO:0036035)
0.4	3.9	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3	2.4	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.3	1.4	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.3	5.4	GO:1902358	oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.3	1.3	GO:0035565	regulation of pronephros size(GO:0035565)
0.3	4.0	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3	2.6	GO:0030647	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.3	2.6	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602) semicircular canal morphogenesis(GO:0048752)
0.3	1.3	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.3	4.7	GO:0006825	copper ion transport(GO:0006825)
0.3	0.9	GO:2000424	regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.3	5.3	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
0.3	1.9	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.3	8.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.3	3.6	GO:0035864	response to potassium ion(GO:0035864)
0.3	0.9	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.3	6.2	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.3	0.9	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.3	0.9	GO:2000853	negative regulation of corticosterone secretion(GO:2000853)
0.3	6.2	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.3	4.8	GO:0031268	pseudopodium organization(GO:0031268)
0.3	1.7	GO:0051775	response to redox state(GO:0051775)
0.3	3.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.3	1.1	GO:0098989	negative regulation of growth hormone secretion(GO:0060125) NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.3	6.3	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.3	1.0	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.3	4.1	GO:0031424	keratinization(GO:0031424)
0.3	6.1	GO:0019835	cytolysis(GO:0019835)
0.3	2.8	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3	2.3	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.3	13.7	GO:0060612	adipose tissue development(GO:0060612)
0.2	1.7	GO:0015722	canalicular bile acid transport(GO:0015722)
0.2	0.7	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2	6.5	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	1.8	GO:0033572	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.2	5.6	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.2	5.7	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2	7.0	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.2	7.2	GO:0046688	response to copper ion(GO:0046688)
0.2	3.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.2	1.0	GO:0098735	cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.2	1.3	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.2	3.7	GO:1903427	negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.2	9.4	GO:0051310	metaphase plate congression(GO:0051310)
0.2	0.7	GO:0061113	pancreas morphogenesis(GO:0061113)
0.2	3.0	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.2	3.8	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.2	3.6	GO:0006491	N-glycan processing(GO:0006491)
0.2	2.5	GO:0001887	selenium compound metabolic process(GO:0001887)
0.2	2.1	GO:0021684	cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) prepulse inhibition(GO:0060134)
0.2	10.0	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.2	12.0	GO:0032092	positive regulation of protein binding(GO:0032092)
0.1	0.6	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	4.3	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	1.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	1.0	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1	0.7	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1	2.9	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.1	10.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	2.5	GO:0002347	response to tumor cell(GO:0002347)
0.1	1.4	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.1	3.2	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1	0.4	GO:0043987	histone H3-S10 phosphorylation(GO:0043987) histone H2A phosphorylation(GO:1990164)
0.1	3.1	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1	0.8	GO:0015074	DNA integration(GO:0015074)
0.1	1.5	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.1	1.5	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.1	0.5	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1	2.3	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.6	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.1	1.3	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.1	0.5	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1	0.8	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
0.1	0.1	GO:0014916	regulation of lung blood pressure(GO:0014916)
0.1	1.6	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	2.5	GO:0097186	amelogenesis(GO:0097186)
0.1	4.5	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.1	3.6	GO:0006900	membrane budding(GO:0006900)
0.1	2.5	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	1.8	GO:0046415	urate metabolic process(GO:0046415)
0.1	5.2	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	4.0	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.1	1.2	GO:0046884	follicle-stimulating hormone secretion(GO:0046884)
0.1	2.3	GO:0042119	neutrophil activation(GO:0042119)
0.1	0.6	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	2.4	GO:0001953	negative regulation of cell-matrix adhesion(GO:0001953)
0.1	0.9	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.3	GO:0032782	bile acid secretion(GO:0032782)
0.1	1.6	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1	3.3	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	1.0	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	1.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	4.0	GO:0022904	respiratory electron transport chain(GO:0022904)
0.1	4.4	GO:0035094	response to nicotine(GO:0035094)
0.1	0.8	GO:0021670	lateral ventricle development(GO:0021670)
0.1	0.3	GO:0021559	trigeminal nerve development(GO:0021559)
0.1	4.8	GO:1902017	regulation of cilium assembly(GO:1902017)
0.1	3.0	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.1	3.3	GO:0030500	regulation of bone mineralization(GO:0030500)
0.1	2.5	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	0.1	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1	1.3	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1	1.8	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.8	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.6	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.5	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1	0.4	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1	0.7	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.9	GO:0045777	positive regulation of blood pressure(GO:0045777)
0.0	2.6	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	1.3	GO:0097352	autophagosome maturation(GO:0097352)
0.0	0.2	GO:0007060	meiotic gene conversion(GO:0006311) male meiosis chromosome segregation(GO:0007060) gene conversion(GO:0035822)
0.0	4.5	GO:0007599	blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0	1.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	7.4	GO:0010506	regulation of autophagy(GO:0010506)
0.0	0.7	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	17.5	GO:0006897	endocytosis(GO:0006897)
0.0	1.4	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580)
0.0	1.1	GO:0048041	cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.9	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	2.0	GO:0030901	midbrain development(GO:0030901)
0.0	0.7	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	2.5	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0	32.0	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	1.0	GO:0046785	microtubule polymerization(GO:0046785)
0.0	1.1	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.0	0.4	GO:0030149	sphingolipid catabolic process(GO:0030149)
0.0	1.9	GO:0006275	regulation of DNA replication(GO:0006275)
0.0	0.3	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.3	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.2	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.1	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.6	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	1.0	GO:0007601	visual perception(GO:0007601)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	23.0	GO:0005579	membrane attack complex(GO:0005579)
2.6	7.7	GO:0005899	insulin receptor complex(GO:0005899)
2.5	32.6	GO:0042627	chylomicron(GO:0042627)
2.1	12.7	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
1.8	9.2	GO:0070195	growth hormone receptor complex(GO:0070195)
1.8	7.1	GO:0005588	collagen type V trimer(GO:0005588)
1.8	10.7	GO:0030478	actin cap(GO:0030478)
1.7	5.2	GO:0097444	spine apparatus(GO:0097444)
1.6	24.3	GO:0032982	myosin filament(GO:0032982)
1.6	7.9	GO:0043293	apoptosome(GO:0043293)
1.6	7.9	GO:0005927	muscle tendon junction(GO:0005927)
1.5	9.3	GO:0005608	laminin-3 complex(GO:0005608)
1.3	9.3	GO:0045293	mRNA editing complex(GO:0045293)
1.2	8.7	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
1.2	10.9	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.1	4.3	GO:0030485	smooth muscle contractile fiber(GO:0030485)
1.1	4.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
1.1	13.9	GO:0031983	vesicle lumen(GO:0031983)
1.0	3.0	GO:0035577	azurophil granule membrane(GO:0035577)
1.0	5.7	GO:0033093	Weibel-Palade body(GO:0033093) rough endoplasmic reticulum lumen(GO:0048237)
0.9	3.8	GO:0044307	dendritic branch(GO:0044307)
0.9	7.0	GO:0031931	TORC1 complex(GO:0031931)
0.8	2.5	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.8	4.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.7	19.5	GO:0031430	M band(GO:0031430)
0.7	2.1	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.7	11.6	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.6	1.7	GO:0044609	DBIRD complex(GO:0044609)
0.5	5.9	GO:0031143	pseudopodium(GO:0031143)
0.5	5.2	GO:1990635	proximal dendrite(GO:1990635)
0.4	3.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.4	11.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3	1.0	GO:0098835	presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3	8.4	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.3	4.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3	5.0	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.3	11.2	GO:0043034	costamere(GO:0043034)
0.3	5.6	GO:0005614	interstitial matrix(GO:0005614)
0.3	1.2	GO:1990761	growth cone lamellipodium(GO:1990761)
0.3	3.9	GO:0097542	ciliary tip(GO:0097542)
0.3	5.7	GO:0030014	CCR4-NOT complex(GO:0030014)
0.3	3.3	GO:0044294	dendritic growth cone(GO:0044294)
0.3	0.9	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3	1.7	GO:0005726	perichromatin fibrils(GO:0005726)
0.3	11.9	GO:0009925	basal plasma membrane(GO:0009925)
0.3	2.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.3	3.1	GO:0005652	nuclear lamina(GO:0005652)
0.3	0.8	GO:0070557	PCNA-p21 complex(GO:0070557)
0.2	5.5	GO:1902711	GABA-A receptor complex(GO:1902711)
0.2	2.9	GO:0032593	insulin-responsive compartment(GO:0032593)
0.2	7.3	GO:0051233	spindle midzone(GO:0051233)
0.2	4.0	GO:0043196	varicosity(GO:0043196)
0.2	0.8	GO:0036157	outer dynein arm(GO:0036157)
0.2	10.3	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2	4.1	GO:0046930	pore complex(GO:0046930)
0.2	6.3	GO:0097228	sperm principal piece(GO:0097228)
0.2	14.1	GO:0045095	keratin filament(GO:0045095)
0.2	3.5	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.2	4.1	GO:0001533	cornified envelope(GO:0001533)
0.2	3.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	2.4	GO:0016580	Sin3 complex(GO:0016580)
0.2	1.3	GO:0000798	nuclear cohesin complex(GO:0000798)
0.2	2.6	GO:0033391	chromatoid body(GO:0033391)
0.1	10.8	GO:0005581	collagen trimer(GO:0005581)
0.1	11.2	GO:0005604	basement membrane(GO:0005604)
0.1	8.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	1.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	2.8	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	46.9	GO:0005667	transcription factor complex(GO:0005667)
0.1	37.8	GO:0043235	receptor complex(GO:0043235)
0.1	10.4	GO:0032587	ruffle membrane(GO:0032587)
0.1	1.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	1.4	GO:0030057	desmosome(GO:0030057)
0.1	19.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	2.0	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	1.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	3.6	GO:0002102	podosome(GO:0002102)
0.1	4.0	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	3.8	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	24.0	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	8.3	GO:0072562	blood microparticle(GO:0072562)
0.1	1.2	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	5.7	GO:0070469	respiratory chain(GO:0070469)
0.1	3.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	0.4	GO:0005879	axonemal microtubule(GO:0005879)
0.1	4.8	GO:0001726	ruffle(GO:0001726)
0.1	1.6	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1	0.6	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	1.0	GO:0008180	COP9 signalosome(GO:0008180)
0.1	0.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	1.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	11.0	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	1.7	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.9	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	1.5	GO:0060170	ciliary membrane(GO:0060170)
0.0	5.5	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	1.4	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	4.3	GO:0000922	spindle pole(GO:0000922)
0.0	1.8	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	94.0	GO:0070062	extracellular exosome(GO:0070062)
0.0	1.4	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.5	GO:0000502	proteasome complex(GO:0000502)
0.0	2.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	2.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.3	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	9.5	GO:0005768	endosome(GO:0005768)
0.0	0.5	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	1.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.2	GO:0005840	ribosome(GO:0005840)
0.0	3.4	GO:0000139	Golgi membrane(GO:0000139)
0.0	11.1	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	4.2	GO:0016607	nuclear speck(GO:0016607)
0.0	0.4	GO:0032040	small-subunit processome(GO:0032040)
0.0	2.3	GO:0015629	actin cytoskeleton(GO:0015629)
0.0	0.9	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.4	28.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
5.2	20.8	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
3.8	11.5	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.7	8.0	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
2.4	11.9	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.3	9.2	GO:0004903	growth hormone receptor activity(GO:0004903)
2.2	6.7	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.2	8.7	GO:0019959	interleukin-8 binding(GO:0019959)
2.1	8.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
1.9	7.7	GO:0051425	PTB domain binding(GO:0051425)
1.9	5.7	GO:0031708	endothelin B receptor binding(GO:0031708)
1.8	12.7	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.8	17.8	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
1.7	5.2	GO:0004159	dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
1.7	22.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
1.5	5.8	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
1.4	4.3	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
1.4	5.8	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
1.4	7.2	GO:0004945	angiotensin type II receptor activity(GO:0004945)
1.4	10.1	GO:0043426	MRF binding(GO:0043426)
1.4	7.2	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.4	2.9	GO:0001595	angiotensin receptor activity(GO:0001595)
1.4	4.2	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
1.4	6.9	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
1.3	7.9	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.2	10.0	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
1.2	7.4	GO:0019211	phosphatase activator activity(GO:0019211)
1.1	4.5	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
1.1	15.6	GO:0031432	titin binding(GO:0031432)
1.1	3.3	GO:0005119	smoothened binding(GO:0005119)
1.0	9.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.0	3.9	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.0	3.8	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.9	20.7	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.9	6.3	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.9	6.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.9	2.6	GO:0047025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.9	7.0	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.8	3.4	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.8	5.7	GO:0071532	ankyrin repeat binding(GO:0071532)
0.8	3.8	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.8	3.0	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.7	7.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7	3.4	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.6	7.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6	7.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.6	4.4	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.6	5.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.6	3.7	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.6	8.5	GO:0033038	bitter taste receptor activity(GO:0033038)
0.6	7.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	7.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.6	6.5	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.6	2.8	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.6	2.8	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.5	2.2	GO:0033149	FFAT motif binding(GO:0033149)
0.5	4.4	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.5	3.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.5	3.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.5	1.5	GO:0016015	morphogen activity(GO:0016015)
0.5	13.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.5	1.9	GO:0003973	(S)-2-hydroxy-acid oxidase activity(GO:0003973)
0.5	7.6	GO:0001972	retinoic acid binding(GO:0001972)
0.5	5.7	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.5	1.4	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.5	3.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.5	8.7	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.5	3.2	GO:0003896	DNA primase activity(GO:0003896)
0.4	15.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.4	3.0	GO:0034711	inhibin binding(GO:0034711)
0.4	5.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.4	2.9	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4	2.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4	17.7	GO:0016831	carboxy-lyase activity(GO:0016831)
0.4	2.5	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4	2.9	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.4	7.7	GO:0043274	phospholipase binding(GO:0043274)
0.4	12.0	GO:0070064	proline-rich region binding(GO:0070064)
0.4	2.7	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.4	8.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.4	1.9	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4	1.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.4	4.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4	5.4	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.3	8.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.3	2.0	GO:0035197	siRNA binding(GO:0035197)
0.3	6.0	GO:0005523	tropomyosin binding(GO:0005523)
0.3	4.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.3	2.3	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3	6.1	GO:0001848	complement binding(GO:0001848)
0.3	6.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.3	2.5	GO:0008430	selenium binding(GO:0008430)
0.3	5.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.3	3.0	GO:0045499	chemorepellent activity(GO:0045499)
0.3	1.2	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3	1.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.3	3.0	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.3	3.7	GO:0016805	dipeptidase activity(GO:0016805)
0.3	19.5	GO:0017022	myosin binding(GO:0017022)
0.3	9.7	GO:0070888	E-box binding(GO:0070888)
0.3	3.1	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.3	1.6	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3	0.8	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3	12.1	GO:0043531	ADP binding(GO:0043531)
0.2	3.9	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.2	1.2	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2	2.3	GO:0070700	BMP receptor binding(GO:0070700)
0.2	1.3	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.2	3.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	27.7	GO:0042826	histone deacetylase binding(GO:0042826)
0.2	5.5	GO:0004890	GABA-A receptor activity(GO:0004890)
0.2	5.7	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2	23.7	GO:0005178	integrin binding(GO:0005178)
0.2	2.8	GO:0042609	CD4 receptor binding(GO:0042609)
0.2	10.1	GO:0019003	GDP binding(GO:0019003)
0.2	0.8	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	1.3	GO:0071253	connexin binding(GO:0071253)
0.2	1.5	GO:1990459	transferrin receptor binding(GO:1990459)
0.2	4.1	GO:0015288	porin activity(GO:0015288)
0.2	2.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.2	3.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2	3.2	GO:0005537	mannose binding(GO:0005537)
0.2	1.7	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.2	2.1	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2	18.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	3.5	GO:0042056	chemoattractant activity(GO:0042056)
0.1	1.0	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	1.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.1	1.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	2.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	10.5	GO:0038024	cargo receptor activity(GO:0038024)
0.1	1.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	2.5	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	4.3	GO:0050681	androgen receptor binding(GO:0050681)
0.1	9.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	3.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	13.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	5.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	1.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	2.9	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	1.5	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	8.7	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	3.9	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	3.0	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	4.7	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	5.6	GO:0008013	beta-catenin binding(GO:0008013)
0.1	34.7	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	1.7	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	0.5	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.7	GO:0015238	drug transmembrane transporter activity(GO:0015238)
0.1	0.6	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	2.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	3.6	GO:0046332	SMAD binding(GO:0046332)
0.1	2.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	1.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	2.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.8	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	1.6	GO:0042169	SH2 domain binding(GO:0042169)
0.1	7.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	1.8	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	4.3	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.1	1.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	0.7	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.6	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	4.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	4.4	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.6	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	10.4	GO:0008017	microtubule binding(GO:0008017)
0.0	0.6	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.6	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	4.0	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	0.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	1.0	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.8	GO:0003777	microtubule motor activity(GO:0003777)
0.0	10.9	GO:0005549	odorant binding(GO:0005549)
0.0	35.8	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	1.7	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	1.5	GO:0019843	rRNA binding(GO:0019843)
0.0	5.4	GO:0004857	enzyme inhibitor activity(GO:0004857)
0.0	0.4	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.7	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	3.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.0	GO:0003823	antigen binding(GO:0003823)
0.0	0.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	3.6	GO:0008134	transcription factor binding(GO:0008134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	38.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.8	16.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.7	13.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.5	9.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.5	29.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.5	3.9	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.5	24.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.4	5.7	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.4	23.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	13.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.3	12.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	13.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.3	5.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	10.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.2	1.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	14.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.2	14.0	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	5.8	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	33.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2	5.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	11.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2	3.0	PID ALK1 PATHWAY	ALK1 signaling events
0.2	10.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	3.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.2	8.9	PID BMP PATHWAY	BMP receptor signaling
0.2	3.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	8.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	6.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	4.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	3.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.2	2.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	6.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	2.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	2.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	4.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	25.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	5.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	0.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	2.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	1.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	3.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	4.3	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	5.1	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	2.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	2.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	1.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	1.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	1.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.8	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.7	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	7.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.4	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.7	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.6	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	20.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.4	25.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
1.1	28.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
1.0	12.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.0	2.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.9	8.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.7	19.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.7	0.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7	19.9	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.7	8.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.7	23.0	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.6	5.9	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.6	8.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.5	9.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.4	9.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.4	17.1	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.4	8.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4	15.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.4	3.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4	5.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.4	11.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.4	13.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.4	5.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.4	6.0	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.4	14.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.4	18.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3	5.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.3	7.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	3.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	3.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	4.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3	5.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	7.7	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.2	19.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	5.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.2	3.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.2	11.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	5.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	4.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	9.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.2	11.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	1.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	2.6	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	4.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.1	2.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	7.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	1.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	2.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	5.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	0.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	17.8	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.1	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	2.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	0.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	3.9	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	0.8	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	1.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	2.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	4.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	3.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	7.0	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	5.3	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	2.4	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.2	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	1.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	2.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Results for Foxp2_Foxp3

Z-value: 0.86

Motif logo

Transcription factors associated with Foxp2_Foxp3

Activity-expression correlation:

Activity profile of Foxp2_Foxp3 motif

Sorted Z-values of Foxp2_Foxp3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxp2_Foxp3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: