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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Fubp1

Z-value: 0.54

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Transcription factors associated with Fubp1

Gene Symbol Gene ID Gene Info
Fubp1
ENSRNOG00000043370 far upstream element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fubp1rn6_v1_chr2_+_257425679_2574256790.241.2e-05Click!

Activity profile of Fubp1 motif

Sorted Z-values of Fubp1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_32973695 18.62 ENSRNOT00000065674
RGD1565323
similar to OTTMUSP00000000621
chr2_+_114386019 13.69 ENSRNOT00000082148
AABR07009834.1

chr13_-_51784639 12.86 ENSRNOT00000089068
Ppp1r12b
protein phosphatase 1, regulatory subunit 12B
chr5_+_142689026 12.44 ENSRNOT00000010007
Fhl3
four and a half LIM domains 3
chr1_+_68436917 10.56 ENSRNOT00000088586
LOC108348118
leucyl-cystinyl aminopeptidase
chr4_-_150185044 10.40 ENSRNOT00000019778
Csgalnact2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr6_-_146195819 10.24 ENSRNOT00000007625
Sp4
Sp4 transcription factor
chr17_+_44766313 9.38 ENSRNOT00000091688
Hist1h1b
histone cluster 1 H1 family member b
chr1_-_57815038 9.11 ENSRNOT00000075401
Rgmb
repulsive guidance molecule family member B
chrX_-_29648359 8.30 ENSRNOT00000086721
ENSRNOT00000006777
Gpm6b
glycoprotein m6b
chr7_+_144565392 8.12 ENSRNOT00000021589
Hoxc11
homeobox C11
chr2_+_207262934 8.06 ENSRNOT00000016833
Ppm1j
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr3_-_52447622 7.06 ENSRNOT00000083552
Scn1a
sodium voltage-gated channel alpha subunit 1
chr2_-_211831551 6.80 ENSRNOT00000039225
ENSRNOT00000090561
Fam102b
family with sequence similarity 102, member B
chr3_-_11382004 6.49 ENSRNOT00000047921
ENSRNOT00000064039
Dnm1
dynamin 1
chrX_+_105575759 6.48 ENSRNOT00000088760
Armcx3
armadillo repeat containing, X-linked 3
chrX_+_78042859 6.37 ENSRNOT00000003286
Lpar4
lysophosphatidic acid receptor 4
chr3_-_61488696 5.96 ENSRNOT00000083045
Lnpk
lunapark, ER junction formation factor
chr20_+_46519431 5.45 ENSRNOT00000077765
AABR07045405.1

chrX_-_76925195 5.43 ENSRNOT00000087977
Atrx
ATRX, chromatin remodeler
chrX_+_105573909 5.00 ENSRNOT00000029664
Armcx3
armadillo repeat containing, X-linked 3
chr9_+_46840992 4.89 ENSRNOT00000019415
Il1r2
interleukin 1 receptor type 2
chr16_+_71629525 4.62 ENSRNOT00000035347
ENSRNOT00000088462
Tacc1
transforming, acidic coiled-coil containing protein 1
chr14_-_87701884 4.57 ENSRNOT00000079338
Mospd1
motile sperm domain containing 1
chr17_-_11916026 4.52 ENSRNOT00000046385
RGD1561671
similar to RIKEN cDNA 2900010M23
chr10_+_15156207 4.21 ENSRNOT00000020363
Ccdc78
coiled-coil domain containing 78
chr1_-_216828581 4.10 ENSRNOT00000066943
ENSRNOT00000088856
Tnfrsf26
tumor necrosis factor receptor superfamily, member 26
chr4_-_120041238 4.06 ENSRNOT00000073799
LOC100911337
40S ribosomal protein S25-like
chr10_-_85825735 3.88 ENSRNOT00000055379
Fbxo47
F-box protein 47
chr1_-_167210919 3.79 ENSRNOT00000027507
Chrna10
cholinergic receptor nicotinic alpha 10 subunit
chr18_-_81807627 3.78 ENSRNOT00000020376
Timm21
translocase of inner mitochondrial membrane 21
chr13_+_90116843 3.73 ENSRNOT00000006306
Cd48
Cd48 molecule
chr2_+_235596123 3.61 ENSRNOT00000074816
Col25a1
collagen type XXV alpha 1 chain
chrX_-_115496045 3.59 ENSRNOT00000051134
LOC100361854
ribosomal protein S26-like
chr3_+_80556668 3.52 ENSRNOT00000079118
Arhgap1
Rho GTPase activating protein 1
chr13_-_72367980 3.50 ENSRNOT00000003928
Cacna1e
calcium voltage-gated channel subunit alpha1 E
chr5_+_164923302 3.31 ENSRNOT00000042285
LOC108349682
60S ribosomal protein L35a
chr20_-_32133431 3.26 ENSRNOT00000000443
Srgn
serglycin
chr12_-_7186873 3.23 ENSRNOT00000050438
LOC103690996
uncharacterized LOC103690996
chr3_+_111699021 3.22 ENSRNOT00000067865
ENSRNOT00000008528
ENSRNOT00000064395
ENSRNOT00000064345
Mga
MGA, MAX dimerization protein
chr13_-_94289333 3.20 ENSRNOT00000078195
Pld5
phospholipase D family, member 5
chr14_-_28536260 3.16 ENSRNOT00000059942
Adgrl3
adhesion G protein-coupled receptor L3
chr2_+_223029559 3.01 ENSRNOT00000045584
AABR07013111.1

chr12_-_43576754 3.00 ENSRNOT00000042331
ENSRNOT00000081780
Med13l
mediator complex subunit 13-like
chr3_+_129599353 2.98 ENSRNOT00000008734
Snap25
synaptosomal-associated protein 25
chr4_+_168689163 2.97 ENSRNOT00000049848
Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr3_-_8955538 2.85 ENSRNOT00000040570
LOC686066
similar to 60S ribosomal protein L38
chr4_+_66670618 2.82 ENSRNOT00000010796
Tbxas1
thromboxane A synthase 1
chr18_+_17403407 2.56 ENSRNOT00000045150
RGD1562608
similar to KIAA1328 protein
chr4_-_114823500 2.48 ENSRNOT00000089870
NEWGENE_1562258
INO80 complex subunit B
chr16_+_90325304 2.37 ENSRNOT00000057310
Slc10a2
solute carrier family 10 member 2
chr17_-_63879166 2.32 ENSRNOT00000049391
ENSRNOT00000045183
Zmynd11
zinc finger, MYND-type containing 11
chr14_-_16276068 2.30 ENSRNOT00000002876
Ccng2
cyclin G2
chr18_+_62852303 2.30 ENSRNOT00000087673
Gnal
G protein subunit alpha L
chr20_+_6356423 2.21 ENSRNOT00000000628
Cdkn1a
cyclin-dependent kinase inhibitor 1A
chr7_-_60742660 2.18 ENSRNOT00000086116
Mdm2
MDM2 proto-oncogene
chr13_+_92167643 2.17 ENSRNOT00000030794
Olr1589
olfactory receptor 1589
chr18_+_48853418 2.15 ENSRNOT00000022792
Csnk1g3
casein kinase 1, gamma 3
chr14_+_89314176 2.14 ENSRNOT00000006765
Upp1
uridine phosphorylase 1
chr13_-_26769374 2.12 ENSRNOT00000003768
Bcl2
BCL2, apoptosis regulator
chr8_-_55276070 2.12 ENSRNOT00000041555
LOC108351703
60S ribosomal protein L27a-like
chr2_+_45104305 2.00 ENSRNOT00000014559
Esm1
endothelial cell-specific molecule 1
chr7_+_116357175 2.00 ENSRNOT00000076790
Ly6e
lymphocyte antigen 6 complex, locus E
chr18_+_51523758 1.96 ENSRNOT00000078518
Gramd3
GRAM domain containing 3
chr7_+_144595960 1.94 ENSRNOT00000021909
Hoxc9
homeobox C9
chr12_+_13715843 1.90 ENSRNOT00000042459
Actb
actin, beta
chrX_+_74824504 1.86 ENSRNOT00000048963
LOC680353
similar to 60S ribosomal protein L38
chr7_+_70445366 1.83 ENSRNOT00000045687
RGD1565117
similar to 40S ribosomal protein S26
chr16_-_32540217 1.82 ENSRNOT00000015130
Hpf1
histone PARylation factor 1
chr18_+_47739140 1.70 ENSRNOT00000082760
Sncaip
synuclein, alpha interacting protein
chr8_+_87211819 1.63 ENSRNOT00000086093
LOC100363289
LRRGT00022-like
chr20_+_4143321 1.58 ENSRNOT00000060366
Btnl2
butyrophilin-like 2
chr8_+_98755104 1.56 ENSRNOT00000056562
Zic4
Zic family member 4
chr8_-_108261021 1.56 ENSRNOT00000040710
LOC100912210
40S ribosomal protein S25-like
chr2_-_111793326 1.50 ENSRNOT00000092660
Nlgn1
neuroligin 1
chr10_+_68588789 1.45 ENSRNOT00000049614
AABR07030122.1

chr10_-_97756521 1.34 ENSRNOT00000045902
Slc16a6
solute carrier family 16, member 6
chr20_+_27212724 1.28 ENSRNOT00000032600
Hnrnph3
heterogeneous nuclear ribonucleoprotein H3
chr4_-_51844331 1.28 ENSRNOT00000003593
Gpr37
G protein-coupled receptor 37
chr1_-_219395623 1.25 ENSRNOT00000040261
Rpl35a
ribosomal protein L35a
chr20_+_48212378 1.24 ENSRNOT00000040519
AABR07045454.1

chr17_+_18358712 1.19 ENSRNOT00000001979
Nup153
nucleoporin 153
chr2_+_76923591 1.17 ENSRNOT00000042759
LOC100360575
signal-regulatory protein alpha-like
chr17_-_9519595 1.09 ENSRNOT00000029885
Ddx46
DEAD-box helicase 46
chr10_-_104522241 1.05 ENSRNOT00000046010
Rps18l1
ribosomal protein S18-like 1
chr1_+_255479261 1.00 ENSRNOT00000079808
Tnks2
tankyrase 2
chr3_-_55451798 0.97 ENSRNOT00000008837
Spc25
SPC25, NDC80 kinetochore complex component
chr15_-_19282873 0.89 ENSRNOT00000075184
NEWGENE_1359268
Smad nuclear interacting protein 1
chr3_-_20914603 0.89 ENSRNOT00000049651
Olr416
olfactory receptor 416
chr3_-_154042099 0.87 ENSRNOT00000033525
Blcap
bladder cancer associated protein
chr1_+_190852985 0.86 ENSRNOT00000040963
Polr3e
RNA polymerase III subunit E
chr4_-_152883210 0.85 ENSRNOT00000056200
Ccdc77
coiled-coil domain containing 77
chr1_+_72756809 0.80 ENSRNOT00000082423
Ppp6r1
protein phosphatase 6, regulatory subunit 1
chr2_-_77784522 0.80 ENSRNOT00000030328
LOC310177
similar to RIKEN cDNA 0610040D20
chr6_+_134844676 0.76 ENSRNOT00000007595
Ppp2r5c
protein phosphatase 2, regulatory subunit B', gamma
chr3_-_76256129 0.70 ENSRNOT00000072741
LOC100912605
olfactory receptor 5D14-like
chr15_-_30147793 0.70 ENSRNOT00000060399
AABR07017693.1

chr1_-_211923929 0.68 ENSRNOT00000054887
Nkx6-2
NK6 homeobox 2
chr10_-_35175647 0.56 ENSRNOT00000078960
Cnot6
CCR4-NOT transcription complex, subunit 6
chr5_-_100977902 0.56 ENSRNOT00000077429
Zdhhc21
zinc finger, DHHC-type containing 21
chr18_+_35850132 0.55 ENSRNOT00000067337
ENSRNOT00000075841
LOC103690064
m7GpppN-mRNA hydrolase-like
chr1_-_91588609 0.49 ENSRNOT00000050931
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr20_+_1764794 0.41 ENSRNOT00000075084
Olr1736
olfactory receptor 1736
chr18_-_27374603 0.39 ENSRNOT00000027244
Nme5
NME/NM23 family member 5
chr4_+_89536647 0.33 ENSRNOT00000058581
Tigd2
tigger transposable element derived 2
chr13_+_92224971 0.25 ENSRNOT00000004674
Olr1593
olfactory receptor 1593
chr20_+_1749716 0.25 ENSRNOT00000048856
Olr1735
olfactory receptor 1735
chr2_-_149754776 0.23 ENSRNOT00000035057
RGD1559622
similar to hypothetical protein C130079G13
chr11_-_782954 0.18 ENSRNOT00000040065
Epha3
Eph receptor A3
chr1_+_65781547 0.11 ENSRNOT00000026204
Zfp329
zinc finger protein 329
chr15_+_47373120 0.10 ENSRNOT00000070815
Rp1l1
RP1 like 1
chr13_+_96122120 0.07 ENSRNOT00000087964
Desi2
desumoylating isopeptidase 2
chr5_+_116420690 0.07 ENSRNOT00000087089
Nfia
nuclear factor I/A
chr19_-_53754602 0.07 ENSRNOT00000035651
Fam92b
family with sequence similarity 92, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of Fubp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.4 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
1.8 5.4 GO:1901580 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
1.7 8.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.6 4.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.3 9.4 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
1.1 3.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.0 3.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.9 6.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.9 6.0 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.8 1.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.7 2.2 GO:1904404 traversing start control point of mitotic cell cycle(GO:0007089) response to formaldehyde(GO:1904404)
0.7 2.1 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671)
0.7 3.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.6 10.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.6 1.8 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.6 4.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.6 8.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.5 7.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 2.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.5 3.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.4 3.5 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.4 2.1 GO:0044206 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.3 0.7 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 3.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 2.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.3 2.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.3 3.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.3 4.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.3 2.3 GO:0009405 pathogenesis(GO:0009405)
0.2 4.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 6.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 3.8 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 2.0 GO:0048242 epinephrine secretion(GO:0048242)
0.1 0.6 GO:2000327 positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 1.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 3.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 2.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.9 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 1.7 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 2.3 GO:0046329 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) negative regulation of JNK cascade(GO:0046329)
0.1 0.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 9.1 GO:0030509 BMP signaling pathway(GO:0030509)
0.1 4.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 3.7 GO:0045576 mast cell activation(GO:0045576)
0.0 8.6 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.9 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 2.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 7.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 11.9 GO:0006412 translation(GO:0006412)
0.0 10.9 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.0 GO:0007052 mitotic spindle organization(GO:0007052)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.8 4.2 GO:0098536 deuterosome(GO:0098536)
0.7 2.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 3.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.4 3.5 GO:0097443 sorting endosome(GO:0097443)
0.4 11.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 3.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.4 7.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 6.5 GO:0043196 varicosity(GO:0043196)
0.3 12.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 3.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 12.9 GO:0031672 A band(GO:0031672)
0.2 1.2 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.0 GO:0031262 Ndc80 complex(GO:0031262)
0.2 1.9 GO:0097433 dense body(GO:0097433)
0.2 3.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 9.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 10.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 12.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.3 GO:0042629 mast cell granule(GO:0042629)
0.1 3.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 5.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.1 3.0 GO:0016592 mediator complex(GO:0016592)
0.1 2.1 GO:0046930 pore complex(GO:0046930)
0.1 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.3 GO:0019013 viral nucleocapsid(GO:0019013)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.9 GO:0016235 aggresome(GO:0016235)
0.0 3.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 5.3 GO:0005840 ribosome(GO:0005840)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.4 GO:0000502 proteasome complex(GO:0000502)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 8.3 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 17.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.3 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.4 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
1.1 5.4 GO:0015616 DNA translocase activity(GO:0015616)
1.1 6.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.7 2.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.7 3.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.7 2.0 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.6 4.9 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.5 10.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.5 9.1 GO:0015026 coreceptor activity(GO:0015026)
0.4 2.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 10.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.4 2.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 2.1 GO:0051434 BH3 domain binding(GO:0051434)
0.3 4.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 7.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.2 3.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 3.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 13.6 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 8.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.2 GO:0043495 protein anchor(GO:0043495)
0.1 7.8 GO:0000049 tRNA binding(GO:0000049)
0.1 1.9 GO:0098918 structural constituent of synapse(GO:0098918)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 8.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 3.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 2.8 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 3.7 GO:0003823 antigen binding(GO:0003823)
0.0 10.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 6.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 8.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 12.4 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 2.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 2.1 GO:0001948 glycoprotein binding(GO:0001948)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 2.0 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 7.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 6.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 2.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 8.0 PID BMP PATHWAY BMP receptor signaling
0.1 4.6 PID AURORA A PATHWAY Aurora A signaling
0.1 5.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.3 PID IL1 PATHWAY IL1-mediated signaling events
0.1 3.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 8.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.7 6.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.5 6.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.5 7.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.4 10.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 2.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 3.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 2.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 9.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 4.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 3.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 3.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase