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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Gmeb2

Z-value: 0.35

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Transcription factors associated with Gmeb2

Gene Symbol Gene ID Gene Info
Gmeb2
ENSRNOG00000013339 glucocorticoid modulatory element binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gmeb2rn6_v1_chr3_-_176791960_1767919600.332.4e-09Click!

Activity profile of Gmeb2 motif

Sorted Z-values of Gmeb2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_55001464 10.49 ENSRNOT00000006618
Ahr
aryl hydrocarbon receptor
chr3_+_171213936 10.40 ENSRNOT00000031586
Pck1
phosphoenolpyruvate carboxykinase 1
chr7_-_141307233 7.07 ENSRNOT00000071885
Racgap1
Rac GTPase-activating protein 1
chr10_-_65424802 6.99 ENSRNOT00000018468
Traf4
Tnf receptor associated factor 4
chr1_+_220325352 6.75 ENSRNOT00000027258
LOC108348098
breast cancer metastasis-suppressor 1 homolog
chr1_+_141391262 5.81 ENSRNOT00000031783
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr7_-_119768082 5.72 ENSRNOT00000009612
Sstr3
somatostatin receptor 3
chr20_+_2501252 5.49 ENSRNOT00000079307
ENSRNOT00000084559
Trim39
tripartite motif-containing 39
chr17_+_15429708 4.59 ENSRNOT00000093261
LOC679342
hypothetical protein LOC679342
chrX_-_15347591 4.33 ENSRNOT00000037066
Timm17b
translocase of inner mitochondrial membrane 17b
chr14_+_42714315 4.23 ENSRNOT00000084095
ENSRNOT00000091449
Phox2b
paired-like homeobox 2b
chr8_+_116054465 4.23 ENSRNOT00000040056
Cish
cytokine inducible SH2-containing protein
chr7_-_14302552 4.15 ENSRNOT00000091368
Brd4
bromodomain containing 4
chr9_-_54457753 3.26 ENSRNOT00000020032
Stat1
signal transducer and activator of transcription 1
chr5_-_147823232 3.21 ENSRNOT00000074345
Iqcc
IQ motif containing C
chr3_+_33641616 3.16 ENSRNOT00000051953
Epc2
enhancer of polycomb homolog 2
chr1_+_219345918 3.14 ENSRNOT00000025018
Cdk2ap2
cyclin-dependent kinase 2 associated protein 2
chr1_+_167538263 3.04 ENSRNOT00000074058
Rrm1
ribonucleotide reductase catalytic subunit M1
chr6_+_52751106 2.79 ENSRNOT00000014373
Twistnb
TWIST neighbor
chrX_+_159703578 2.77 ENSRNOT00000001162
Cd40lg
CD40 ligand
chr11_+_47243342 2.75 ENSRNOT00000041116
Nfkbiz
NFKB inhibitor zeta
chr10_-_85725429 2.66 ENSRNOT00000005471
Rpl23
ribosomal protein L23
chr17_-_13586554 2.61 ENSRNOT00000041371
Secisbp2
SECIS binding protein 2
chr12_-_24724997 2.41 ENSRNOT00000025560
Abhd11
abhydrolase domain containing 11
chr8_+_118206698 2.40 ENSRNOT00000082607
ENSRNOT00000064140
Smarcc1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr6_-_80334522 2.38 ENSRNOT00000059316
Fbxo33
F-box protein 33
chr7_-_120780108 2.36 ENSRNOT00000018185
Ddx17
DEAD-box helicase 17
chr8_+_104040934 2.35 ENSRNOT00000081204
Tfdp2
transcription factor Dp-2
chr6_+_8346704 2.33 ENSRNOT00000092218
AC111831.2

chr19_+_37668693 2.25 ENSRNOT00000084970
Pard6a
par-6 family cell polarity regulator alpha
chr8_+_117280705 2.25 ENSRNOT00000085038
Usp19
ubiquitin specific peptidase 19
chr1_+_167538744 2.24 ENSRNOT00000093070
Rrm1
ribonucleotide reductase catalytic subunit M1
chr7_-_12399910 2.23 ENSRNOT00000021677
RGD1562114
RGD1562114
chr8_+_79660657 2.22 ENSRNOT00000090970
Ccpg1
cell cycle progression 1
chr9_+_10428853 1.85 ENSRNOT00000074253
Lonp1
lon peptidase 1, mitochondrial
chr17_-_14589154 1.71 ENSRNOT00000073035
Nol8
nucleolar protein 8
chr1_+_154377447 1.65 ENSRNOT00000084268
ENSRNOT00000092086
ENSRNOT00000091470
ENSRNOT00000025415
Picalm
phosphatidylinositol binding clathrin assembly protein
chr11_-_31805728 1.63 ENSRNOT00000032162
Gart
phosphoribosylglycinamide formyltransferase
chr15_-_19733967 1.61 ENSRNOT00000012036
Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr10_-_56286391 1.59 ENSRNOT00000018670
Senp3
Sumo1/sentrin/SMT3 specific peptidase 3
chr19_+_16415636 1.59 ENSRNOT00000089975
Irx5
iroquois homeobox 5
chr20_-_27308069 1.59 ENSRNOT00000056047
Slc25a16
solute carrier family 25 member 16
chr7_+_120202601 1.58 ENSRNOT00000082862
AC096473.3

chr6_+_96871625 1.57 ENSRNOT00000012361
Snapc1
small nuclear RNA activating complex, polypeptide 1
chr14_+_84211600 1.55 ENSRNOT00000005996
Pes1
pescadillo ribosomal biogenesis factor 1
chr2_+_243422811 1.51 ENSRNOT00000014694
Trmt10a
tRNA methyltransferase 10A
chr19_+_55300395 1.50 ENSRNOT00000092169
Ctu2
cytosolic thiouridylase subunit 2
chrX_+_15348138 1.48 ENSRNOT00000010536
Pqbp1
polyglutamine binding protein 1
chr1_+_127010588 1.40 ENSRNOT00000016939
Chsy1
chondroitin sulfate synthase 1
chr5_+_148320438 1.39 ENSRNOT00000018742
Pef1
penta-EF hand domain containing 1
chr11_-_71419223 1.38 ENSRNOT00000002407
Tfrc
transferrin receptor
chr12_+_11179329 1.29 ENSRNOT00000001302
Zfp394
zinc finger protein 394
chr14_-_86706626 1.22 ENSRNOT00000082893
H2afv
H2A histone family, member V
chr1_-_175895510 1.19 ENSRNOT00000064535
Eif4g2
eukaryotic translation initiation factor 4, gamma 2
chrX_-_15504165 1.16 ENSRNOT00000006233
Otud5
OTU deubiquitinase 5
chr16_+_8207223 1.16 ENSRNOT00000026751
Oxnad1
oxidoreductase NAD-binding domain containing 1
chr10_+_86724427 1.12 ENSRNOT00000013204
Casc3
cancer susceptibility candidate 3
chr1_-_259674425 1.10 ENSRNOT00000091116
LOC108348083
delta-1-pyrroline-5-carboxylate synthase
chrX_-_105417323 1.08 ENSRNOT00000015494
Gla
galactosidase, alpha
chr14_+_2100106 1.02 ENSRNOT00000000064
Gak
cyclin G associated kinase
chr1_-_259089632 1.01 ENSRNOT00000020940
ENSRNOT00000091297
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr6_-_50943488 0.90 ENSRNOT00000068419
Dus4l
dihydrouridine synthase 4-like
chr17_-_15429322 0.87 ENSRNOT00000093381
Nol8
nucleolar protein 8
chr13_-_73704480 0.80 ENSRNOT00000005296
Tor1aip1
torsin 1A interacting protein 1
chr7_-_120780641 0.77 ENSRNOT00000076164
Ddx17
DEAD-box helicase 17
chr7_-_29282039 0.74 ENSRNOT00000067777
RGD1561102
similar to ribosomal protein S12
chr10_+_97647111 0.74 ENSRNOT00000055062
Gna13
G protein subunit alpha 13
chr4_-_176789304 0.74 ENSRNOT00000018057
Kcnj8
potassium voltage-gated channel subfamily J member 8
chr12_-_39679510 0.67 ENSRNOT00000001722
Gpn3
GPN-loop GTPase 3
chr10_-_56289882 0.61 ENSRNOT00000090762
ENSRNOT00000056903
Tnfsf13
tumor necrosis factor superfamily member 13
chr7_-_70407177 0.60 ENSRNOT00000049895
Os9
OS9, endoplasmic reticulum lectin
chr4_-_98342887 0.58 ENSRNOT00000010156
Tacstd2
tumor-associated calcium signal transducer 2
chr18_-_27749235 0.55 ENSRNOT00000026696
Hspa9
heat shock protein family A member 9
chr20_+_28027054 0.52 ENSRNOT00000071386
ENSRNOT00000001044
Ranbp2
RAN binding protein 2
chr13_-_73704678 0.44 ENSRNOT00000005280
Tor1aip1
torsin 1A interacting protein 1
chr9_+_88110731 0.43 ENSRNOT00000088677
Rhbdd1
rhomboid domain containing 1
chr9_-_98597359 0.30 ENSRNOT00000027506
Per2
period circadian clock 2
chr8_-_132790778 0.26 ENSRNOT00000008255
ENSRNOT00000091431
Lztfl1
leucine zipper transcription factor-like 1
chr20_-_5455632 0.21 ENSRNOT00000000552
Wdr46
WD repeat domain 46
chr20_-_32080088 0.21 ENSRNOT00000080773
Supv3l1
Suv3 like RNA helicase
chr5_+_157848206 0.20 ENSRNOT00000039663
ENSRNOT00000082138
Ubr4
ubiquitin protein ligase E3 component n-recognin 4
chr13_-_78852160 0.16 ENSRNOT00000039082
ENSRNOT00000076514
Zbtb37
zinc finger and BTB domain containing 37
chr3_+_164986421 0.10 ENSRNOT00000039403
Mocs3
molybdenum cofactor synthesis 3
chr1_-_190370499 0.07 ENSRNOT00000084389
AABR07005618.1

chr9_+_114022137 0.04 ENSRNOT00000007657
Map3k7
mitogen activated protein kinase kinase kinase 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Gmeb2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.5 GO:0040009 regulation of growth rate(GO:0040009)
2.6 10.4 GO:0006114 glycerol biosynthetic process(GO:0006114)
2.4 7.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.4 4.2 GO:0021550 medulla oblongata development(GO:0021550) sensory system development(GO:0048880)
1.0 5.8 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.0 5.7 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.9 2.6 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.8 3.3 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.8 6.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.7 2.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.6 7.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 4.2 GO:2000002 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
0.6 1.2 GO:1905077 regulation of interleukin-17 secretion(GO:1905076) negative regulation of interleukin-17 secretion(GO:1905077)
0.6 1.7 GO:1902962 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.5 1.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.5 1.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.4 2.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.4 1.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 2.7 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 2.8 GO:0033590 response to cobalamin(GO:0033590)
0.3 1.0 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.3 5.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 3.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.3 1.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 4.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 1.6 GO:0006041 glucosamine metabolic process(GO:0006041)
0.3 1.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 5.5 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.2 2.6 GO:1902570 protein localization to nucleolus(GO:1902570)
0.2 0.7 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 2.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 3.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 0.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 2.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 0.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 1.6 GO:0007000 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) nucleolus organization(GO:0007000)
0.2 1.6 GO:0016926 protein desumoylation(GO:0016926)
0.2 1.4 GO:0033572 transferrin transport(GO:0033572)
0.2 0.9 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 1.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 1.9 GO:0010044 response to aluminum ion(GO:0010044)
0.1 2.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1 4.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.2 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.1 0.3 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.1 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 2.8 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 1.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.8 7.1 GO:0097149 centralspindlin complex(GO:0097149)
1.3 5.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.8 3.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.5 1.6 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.5 4.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.4 4.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.4 1.6 GO:0070545 PeBoW complex(GO:0070545)
0.3 6.8 GO:0070822 Sin3-type complex(GO:0070822)
0.2 2.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 2.4 GO:0071564 npBAF complex(GO:0071564)
0.2 1.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.5 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.2 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.6 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 5.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.2 GO:0045025 mitochondrial degradosome(GO:0045025)
0.1 1.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 2.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 10.3 GO:0005730 nucleolus(GO:0005730)
0.0 3.4 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.4 4.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
1.0 5.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.9 5.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 5.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.5 1.6 GO:0016882 cyclo-ligase activity(GO:0016882)
0.5 10.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.5 1.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.4 2.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 2.6 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.4 1.6 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.4 2.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 3.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 7.0 GO:0031996 thioesterase binding(GO:0031996)
0.3 2.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 1.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.3 3.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 0.7 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.2 7.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 6.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 1.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 0.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.1 GO:0016936 galactoside binding(GO:0016936)
0.1 3.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 2.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 4.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 4.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 5.8 GO:0003682 chromatin binding(GO:0003682)
0.0 3.4 GO:0003712 transcription cofactor activity(GO:0003712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 11.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 7.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 6.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 7.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.6 PID E2F PATHWAY E2F transcription factor network
0.1 2.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 3.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 5.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 3.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 7.1 REACTOME KINESINS Genes involved in Kinesins
0.2 4.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 4.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 5.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 3.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.7 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes