Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Hes1

Z-value: 0.74

Motif logo

Transcription factors associated with Hes1

Gene Symbol Gene ID Gene Info
ENSRNOG00000001720 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hes1rn6_v1_chr11_-_74315248_74315248-0.504.9e-22Click!

Activity profile of Hes1 motif

Sorted Z-values of Hes1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_153217782 13.58 ENSRNOT00000015499
CECR2, histone acetyl-lysine reader
chr14_-_86297623 12.86 ENSRNOT00000067162
ENSRNOT00000081607
ENSRNOT00000085265
calcium/calmodulin-dependent protein kinase II beta
chr13_-_98480419 12.64 ENSRNOT00000086306
coenzyme Q8A
chr2_+_207108552 11.89 ENSRNOT00000027234
solute carrier family 16 member 1
chr8_+_48422036 10.71 ENSRNOT00000036051
ubiquitin specific peptidase 2
chr3_+_150910398 10.57 ENSRNOT00000055310
tumor protein p53 inducible nuclear protein 2
chr8_+_48716939 10.50 ENSRNOT00000015810
solute carrier family 37 member 4
chr7_-_119689938 10.45 ENSRNOT00000000200
transmembrane protease, serine 6
chr7_+_126619196 9.15 ENSRNOT00000030082
peroxisome proliferator activated receptor alpha
chr15_-_52029816 9.05 ENSRNOT00000013067
solute carrier family 39 member 14
chr12_+_39553903 8.59 ENSRNOT00000001738
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr2_-_260596777 8.59 ENSRNOT00000009370
LIM homeobox 8
chr5_+_156810991 8.05 ENSRNOT00000055904

chr15_-_27819376 8.03 ENSRNOT00000067400
RIKEN cDNA A930018M24 gene
chr10_-_109821807 8.00 ENSRNOT00000054949
pyrroline-5-carboxylate reductase 1
chr1_-_143535583 7.99 ENSRNOT00000087785
homer scaffolding protein 2
chr10_-_29450644 7.67 ENSRNOT00000087937
adrenoceptor alpha 1B
chr7_-_70842405 7.33 ENSRNOT00000047449
neurexophilin 4
chr9_+_10428853 7.31 ENSRNOT00000074253
lon peptidase 1, mitochondrial
chr19_+_11473541 7.29 ENSRNOT00000082066
autocrine motility factor receptor
chr6_+_30638733 7.13 ENSRNOT00000082885
rRNA promoter binding protein
chr4_+_10823281 7.12 ENSRNOT00000066739
putative homeodomain transcription factor 2
chr10_+_40208223 7.01 ENSRNOT00000000772
histidine triad nucleotide binding protein 1
chr2_-_22385676 6.89 ENSRNOT00000065224
thrombospondin 4
chr2_-_22385855 6.81 ENSRNOT00000083531
thrombospondin 4
chr20_-_10386663 6.77 ENSRNOT00000045275
ENSRNOT00000042432
cystathionine beta synthase
chr2_+_127845034 6.75 ENSRNOT00000044804
La ribonucleoprotein domain family, member 1B
chr10_-_62699723 6.60 ENSRNOT00000086706
coronin 6
chr5_-_152746588 6.47 ENSRNOT00000022908
mitochondrial fission regulator 1-like
chr11_-_38420032 6.37 ENSRNOT00000002209
ENSRNOT00000080681
C2 calcium-dependent domain containing 2
chr9_-_82214440 6.12 ENSRNOT00000024419
Indian hedgehog
chr9_+_47386626 6.10 ENSRNOT00000021270
solute carrier family 9 member A2
chr1_-_265899958 6.02 ENSRNOT00000026013
paired-like homeodomain 3
chr5_-_152589719 5.91 ENSRNOT00000022522
exostosin-like glycosyltransferase 1
chr1_+_215460226 5.48 ENSRNOT00000027270
hypothetical protein LOC685544
chr4_-_82229397 5.36 ENSRNOT00000089432
homeo box A13
chr1_-_263959318 5.26 ENSRNOT00000068007
polycystin 2 like 1, transient receptor potential cation channel
chr1_-_90091287 5.24 ENSRNOT00000032613
glucose-6-phosphate isomerase
chr7_+_70452579 5.23 ENSRNOT00000046099
beta-1,4-N-acetyl-galactosaminyl transferase 1
chrX_+_156227830 5.10 ENSRNOT00000083949
similar to ESO3 protein
chr4_-_117296082 5.00 ENSRNOT00000021097
early growth response 4
chr1_-_82452281 4.99 ENSRNOT00000027995
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr3_+_114176309 4.97 ENSRNOT00000023350
sorbitol dehydrogenase
chr1_+_166893734 4.96 ENSRNOT00000026702
paired-like homeobox 2a
chr8_-_111850393 4.94 ENSRNOT00000044956
CDV3 homolog
chr3_+_154395187 4.89 ENSRNOT00000050810
V-set and transmembrane domain containing 2 like
chr3_+_147585947 4.88 ENSRNOT00000006833
scratch family transcriptional repressor 2
chr7_+_54980120 4.81 ENSRNOT00000005690
ENSRNOT00000005773
potassium voltage-gated channel subfamily C member 2
chr12_+_45026886 4.79 ENSRNOT00000001500
phosphatidylethanolamine binding protein 1
chr13_+_83972212 4.78 ENSRNOT00000004394
cellular repressor of E1A-stimulated genes 1
chr7_+_66595742 4.75 ENSRNOT00000031191
ubiquitin specific peptidase 15
chr7_-_28040510 4.72 ENSRNOT00000005674
achaete-scute family bHLH transcription factor 1
chr1_-_86948845 4.67 ENSRNOT00000027212
NFKB inhibitor beta
chr13_+_48745860 4.64 ENSRNOT00000010242
solute carrier family 45, member 3
chr9_-_69953182 4.61 ENSRNOT00000015852
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr8_-_130491998 4.59 ENSRNOT00000064114
HIG1 hypoxia inducible domain family, member 1A
chr8_-_117353672 4.54 ENSRNOT00000027262
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr9_-_100624638 4.53 ENSRNOT00000051155
high density lipoprotein binding protein
chr5_-_156811650 4.51 ENSRNOT00000068065
family with sequence similarity 43, member B
chr7_-_70452675 4.48 ENSRNOT00000090498

chr10_+_38814799 4.39 ENSRNOT00000074769
shroom family member 1
chr7_-_18634079 4.31 ENSRNOT00000010031
angiopoietin-like 4
chr5_-_148492232 4.09 ENSRNOT00000017577
serine incorporator 2
chr10_-_53037816 3.99 ENSRNOT00000057509
shisa family member 6
chr6_-_141008427 3.92 ENSRNOT00000074472

chr3_+_13838304 3.87 ENSRNOT00000025067
heat shock protein family A member 5
chr10_+_47281786 3.83 ENSRNOT00000089123
potassium voltage-gated channel subfamily J member 12
chr14_+_2789650 3.81 ENSRNOT00000030479
family with sequence similarity 69, member A
chr2_-_164684985 3.77 ENSRNOT00000057504
retinoic acid receptor responder 1
chr1_+_86923591 3.69 ENSRNOT00000027166
seryl-tRNA synthetase 2, mitochondrial
chr15_-_19733967 3.59 ENSRNOT00000012036
glucosamine-phosphate N-acetyltransferase 1
chr3_+_125503638 3.50 ENSRNOT00000028900
cardiolipin synthase 1
chr8_-_1450138 3.46 ENSRNOT00000008062
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr3_-_22951711 3.39 ENSRNOT00000016876
ENSRNOT00000085981
proteasome subunit beta 7
chr13_+_103300932 3.34 ENSRNOT00000085214
ENSRNOT00000038264
glutamyl-prolyl-tRNA synthetase
chr1_+_88686731 3.26 ENSRNOT00000028222
RNA polymerase II subunit I
chr1_-_86923575 3.25 ENSRNOT00000027029
mitochondrial ribosomal protein S12
chr10_+_109614965 3.21 ENSRNOT00000071432
tetraspanin 10
chr10_-_56531483 3.18 ENSRNOT00000022343
eukaryotic translation initiation factor 5A
chr1_+_209768696 3.14 ENSRNOT00000022406
glutaredoxin 3
chr14_+_60764409 3.11 ENSRNOT00000005168
leucine-rich repeat LGI family, member 2
chr12_+_47218969 3.05 ENSRNOT00000081343
ENSRNOT00000038395
unc-119 lipid binding chaperone B
chr10_+_43633035 3.04 ENSRNOT00000077764
interferon gamma induced GTPase
chr5_-_152446775 3.01 ENSRNOT00000021919
cation channel, sperm associated 4
chr8_-_53146953 3.01 ENSRNOT00000045356
zinc finger and BTB domain containing 16
chr1_+_86948918 3.00 ENSRNOT00000084839
sirtuin 2
chr10_+_86711240 2.97 ENSRNOT00000012812
male specific lethal 1 homolog
chr2_+_189400696 2.96 ENSRNOT00000046919
ENSRNOT00000089801
similar to NICE-3
chr8_+_59278262 2.96 ENSRNOT00000017053
DnaJ heat shock protein family (Hsp40) member A4
chr5_+_63056089 2.94 ENSRNOT00000081090
transforming growth factor, beta receptor 1
chr1_+_85112834 2.91 ENSRNOT00000026107
dual specificity tyrosine phosphorylation regulated kinase 1B
chr2_-_210550490 2.90 ENSRNOT00000081835
ENSRNOT00000025222
ENSRNOT00000086403
colony stimulating factor 1
chr18_+_72005581 2.88 ENSRNOT00000072519
zinc finger and BTB domain containing 7C
chr7_-_117259791 2.87 ENSRNOT00000086550
plectin
chr2_-_197814808 2.85 ENSRNOT00000074156
ADAMTS-like 4
chr4_+_116968000 2.84 ENSRNOT00000020786
empty spiracles homeobox 1
chr7_+_126939925 2.82 ENSRNOT00000022746
GRAM domain containing 4
chr15_-_34198921 2.80 ENSRNOT00000024991
neural retina leucine zipper
chr3_+_56030915 2.71 ENSRNOT00000010489
phosphatase, orphan 2
chr19_+_54553419 2.69 ENSRNOT00000025392
junctophilin 3
chr15_+_51756978 2.68 ENSRNOT00000024067
early growth response 3
chr1_-_168144280 2.61 ENSRNOT00000020969
olfactory receptor 69
chr4_+_32373641 2.60 ENSRNOT00000076086
distal-less homeobox 6
chr15_-_34898237 2.59 ENSRNOT00000091428

chr3_-_22952063 2.55 ENSRNOT00000083850
proteasome subunit beta 7
chr6_-_138931429 2.54 ENSRNOT00000090584
Ighg protein-like
chr7_-_144272578 2.53 ENSRNOT00000020676
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr5_+_134737030 2.47 ENSRNOT00000066161
ENSRNOT00000057061
kinocilin
chr17_-_89923990 2.46 ENSRNOT00000071150
acyl-CoA-binding domain-containing protein 5-like
chr1_+_213334956 2.45 ENSRNOT00000073278
olfactory receptor 309
chr11_+_70034139 2.43 ENSRNOT00000002450
uridine monophosphate synthetase
chr10_+_34631398 2.40 ENSRNOT00000046027
olfactory receptor 1391
chr10_+_14668316 2.33 ENSRNOT00000091891
similar to protease, serine, 28
chr6_-_141062581 2.30 ENSRNOT00000073446

chr17_-_89923423 2.28 ENSRNOT00000076964
acyl-CoA binding domain containing 5
chr2_+_168228099 2.23 ENSRNOT00000074681
vomeronasal 1 receptor 56
chr4_-_122237754 2.15 ENSRNOT00000029915
carbohydrate sulfotransferase 13
chr9_-_113331319 2.08 ENSRNOT00000020681
VAMP associated protein A
chr13_-_93746994 2.05 ENSRNOT00000005072
opsin 3
chr13_-_88307988 2.04 ENSRNOT00000003812
hydroxysteroid (17-beta) dehydrogenase 7
chr11_+_27364916 2.04 ENSRNOT00000002151
BTB domain and CNC homolog 1
chr17_-_23923792 1.98 ENSRNOT00000018739
glucose-fructose oxidoreductase domain containing 1
chr17_+_85356042 1.88 ENSRNOT00000022201
COMM domain containing 3
chr1_-_125967756 1.87 ENSRNOT00000031488
family with sequence similarity 189, member A1
chr2_-_128002005 1.85 ENSRNOT00000018796
progesterone receptor membrane component 2
chr10_+_34402482 1.84 ENSRNOT00000072317
putative olfactory receptor
chr9_+_94310921 1.82 ENSRNOT00000026646
eukaryotic translation initiation factor 4E family member 2
chr6_+_93539271 1.78 ENSRNOT00000078791
translocase of outer mitochondrial membrane 20 homolog (yeast)-like
chr12_-_13998172 1.72 ENSRNOT00000001476
WD repeat domain, phosphoinositide interacting 2
chr4_+_119997268 1.70 ENSRNOT00000073429
ribophorin I
chr1_-_212633304 1.70 ENSRNOT00000025611
olfactory receptor 286
chr16_+_20668971 1.70 ENSRNOT00000027073
ubiquitin A-52 residue ribosomal protein fusion product 1
chr2_-_179704629 1.64 ENSRNOT00000083361
ENSRNOT00000077941
glutamate ionotropic receptor AMPA type subunit 2
chr2_+_9578345 1.64 ENSRNOT00000021756
metallo-beta-lactamase domain containing 2
chr5_-_163167299 1.59 ENSRNOT00000022478
TNF receptor superfamily member 1B
chr4_+_342302 1.58 ENSRNOT00000009233
insulin induced gene 1
chr19_-_39646693 1.58 ENSRNOT00000019104
proteasome 26S subunit, non-ATPase 7
chr3_+_65815080 1.58 ENSRNOT00000006429
ubiquitin-conjugating enzyme E2E 3
chr1_-_168725656 1.57 ENSRNOT00000040224
olfactory receptor 115
chr12_-_24578761 1.51 ENSRNOT00000076209
transducin (beta)-like 2
chr3_+_154507035 1.48 ENSRNOT00000017265
regulation of nuclear pre-mRNA domain containing 1B
chr8_-_25669394 1.48 ENSRNOT00000036738
dpy-19 like 1
chr1_-_171028743 1.47 ENSRNOT00000026488
olfactory receptor 223
chr8_-_115981910 1.45 ENSRNOT00000019867
dedicator of cyto-kinesis 3
chr1_+_82452469 1.44 ENSRNOT00000028026
exosome component 5
chr7_-_2986935 1.42 ENSRNOT00000081125
ENSRNOT00000006578
proliferation-associated 2G4
chr9_+_100080144 1.42 ENSRNOT00000071411
arginyl aminopeptidase like 1
chr5_-_28349927 1.42 ENSRNOT00000008725
OTU domain containing 6B
chr1_-_167308827 1.41 ENSRNOT00000027590
ENSRNOT00000027575
nucleoporin 98
chr7_+_130474279 1.41 ENSRNOT00000092388
SH3 and multiple ankyrin repeat domains 3
chr9_+_10013854 1.40 ENSRNOT00000077653
ENSRNOT00000072033
KH-type splicing regulatory protein
chr7_-_136853957 1.38 ENSRNOT00000008985
neural EGFL like 2
chr20_-_5533448 1.35 ENSRNOT00000000568
cutA divalent cation tolerance homolog
chr10_-_45923829 1.35 ENSRNOT00000035285
olfactory receptor 1462
chr17_+_23986758 1.34 ENSRNOT00000024066
sirtuin 5
chr3_-_51297852 1.34 ENSRNOT00000001607
cordon-bleu WH2 repeat protein-like 1
chr10_-_79097807 1.32 ENSRNOT00000003421
kinesin family member 2B
chr6_-_28464118 1.32 ENSRNOT00000068214
EFR3 homolog B
chr12_-_12782139 1.29 ENSRNOT00000001392
ENSRNOT00000079836
eukaryotic translation initiation factor 2 alpha kinase 1
chr9_-_66033871 1.28 ENSRNOT00000035209
ALS2, alsin Rho guanine nucleotide exchange factor
chr5_+_63050758 1.27 ENSRNOT00000009452
transforming growth factor, beta receptor 1
chr1_-_214074663 1.27 ENSRNOT00000026215
chitinase domain-containing protein 1-like
chr1_+_218487824 1.26 ENSRNOT00000017958
MAS related GPR family member D
chr8_+_5734348 1.25 ENSRNOT00000013119
matrix metallopeptidase 10
chrX_+_156716604 1.23 ENSRNOT00000092207
interleukin-1 receptor-associated kinase 1
chr1_-_18058055 1.22 ENSRNOT00000020988
protein tyrosine phosphatase, receptor type, K
chr3_+_112371677 1.21 ENSRNOT00000013316
HAUS augmin-like complex subunit 2-like
chr4_+_84854386 1.21 ENSRNOT00000013620
maturin, neural progenitor differentiation regulator homolog
chr5_+_154205402 1.19 ENSRNOT00000064925
serine and arginine rich splicing factor 10
chr7_-_75364166 1.18 ENSRNOT00000036852
sorting nexin 31
chr5_-_154363329 1.18 ENSRNOT00000064596
elongin A
chr1_+_154377447 1.15 ENSRNOT00000084268
ENSRNOT00000092086
ENSRNOT00000091470
ENSRNOT00000025415
phosphatidylinositol binding clathrin assembly protein
chr6_+_42852683 1.15 ENSRNOT00000079185
ornithine decarboxylase 1
chr3_-_165700489 1.10 ENSRNOT00000017008
zinc finger protein 93
chr3_-_176791960 1.10 ENSRNOT00000018237
glucocorticoid modulatory element binding protein 2
chr7_-_139929895 1.10 ENSRNOT00000047272
olfactory receptor 1104
chr3_-_175479395 1.07 ENSRNOT00000077308
histamine receptor H3
chr9_+_94310469 1.06 ENSRNOT00000065743
eukaryotic translation initiation factor 4E family member 2
chr3_-_79165698 1.02 ENSRNOT00000032617
olfactory receptor 744
chr10_-_6870011 1.00 ENSRNOT00000003439
similar to CG4768-PA
chr10_+_88764732 0.98 ENSRNOT00000026662
signal transducer and activator of transcription 5A
chrX_+_42558931 0.98 ENSRNOT00000044129
patched domain containing 1
chr20_-_5533600 0.97 ENSRNOT00000072319
cutA divalent cation tolerance homolog
chr15_+_4658246 0.96 ENSRNOT00000008391
SAYSVFN motif domain containing 1
chr20_+_7818289 0.96 ENSRNOT00000042539
peroxisome proliferator-activated receptor delta
chr3_-_94419048 0.95 ENSRNOT00000015775
homeodomain interacting protein kinase 3
chr1_+_214534284 0.94 ENSRNOT00000064254
adaptor-related protein complex 2, alpha 2 subunit
chr3_+_138504214 0.93 ENSRNOT00000091529
lysine acetyltransferase 14
chr1_+_128199322 0.89 ENSRNOT00000075131
LysM domain containing 4
chr10_+_102136283 0.88 ENSRNOT00000003735
somatostatin receptor 2
chr13_-_47670407 0.87 ENSRNOT00000035044
interleukin 19
chr2_-_187863503 0.85 ENSRNOT00000093036
ENSRNOT00000026705
ENSRNOT00000082174
lamin A/C
chr9_+_29984077 0.85 ENSRNOT00000075592
beta-1,3-glucuronyltransferase 2
chr4_-_121969446 0.81 ENSRNOT00000085001
vomeronasal 1 receptor 99
chr13_-_88061108 0.80 ENSRNOT00000003774
regulator of G-protein signaling 4
chr14_-_2934571 0.79 ENSRNOT00000049772
ubiquitin-conjugating enzyme E2D 4 (putative)
chr10_-_31052102 0.78 ENSRNOT00000007917
tRNA-histidine guanylyltransferase 1-like
chr6_-_42473738 0.77 ENSRNOT00000033327
potassium voltage-gated channel modifier subfamily F member 1
chr7_+_12043794 0.74 ENSRNOT00000039813
ATPase phospholipid transporting 8B3
chr8_-_55050194 0.73 ENSRNOT00000013197
hypothetical LOC100151767

Network of associatons between targets according to the STRING database.

First level regulatory network of Hes1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.9 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
2.9 8.6 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) calcium ion import into sarcoplasmic reticulum(GO:1990036)
2.7 13.7 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
2.7 8.0 GO:0055129 L-proline biosynthetic process(GO:0055129)
2.6 7.7 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) positive regulation of glycogen catabolic process(GO:0045819)
2.5 9.9 GO:1904313 response to methamphetamine hydrochloride(GO:1904313)
2.4 9.7 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
2.3 9.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.3 6.8 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) hydrogen sulfide biosynthetic process(GO:0070814)
2.0 6.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.8 5.4 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
1.7 5.0 GO:0006059 hexitol metabolic process(GO:0006059)
1.5 4.6 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.5 10.5 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
1.4 4.2 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.4 4.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
1.3 11.9 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.2 13.6 GO:0001842 neural fold formation(GO:0001842)
1.2 4.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.1 3.3 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
1.0 5.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.0 3.0 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.0 2.9 GO:1904124 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.9 10.4 GO:0097264 self proteolysis(GO:0097264)
0.9 2.8 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.9 4.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.8 9.1 GO:1903874 ferrous iron transport(GO:0015684) zinc II ion transmembrane import(GO:0071578) ferrous iron transmembrane transport(GO:1903874)
0.8 4.8 GO:0021759 globus pallidus development(GO:0021759)
0.8 12.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.8 5.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.7 11.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.7 3.5 GO:0006553 lysine metabolic process(GO:0006553)
0.6 3.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.6 3.0 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.6 3.6 GO:0006041 glucosamine metabolic process(GO:0006041)
0.6 2.3 GO:0030242 pexophagy(GO:0030242)
0.5 4.8 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.5 3.2 GO:0045901 regulation of translational termination(GO:0006449) positive regulation of translational elongation(GO:0045901)
0.5 5.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.5 7.3 GO:0010044 response to aluminum ion(GO:0010044)
0.5 4.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.5 3.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.5 1.4 GO:1902962 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.5 1.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.5 6.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 1.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 1.2 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
0.4 8.0 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.4 1.5 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 2.8 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.3 2.4 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.3 1.3 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
0.3 1.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 1.4 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.3 3.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 2.9 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 3.7 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.3 2.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.3 5.9 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.2 4.6 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.2 1.4 GO:0034475 U4 snRNA 3'-end processing(GO:0034475) DNA deamination(GO:0045006) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 4.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.7 GO:0007308 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.2 2.0 GO:1990637 estrogen biosynthetic process(GO:0006703) response to prolactin(GO:1990637)
0.2 2.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 2.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 1.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 0.8 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.2 1.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 1.3 GO:0051036 regulation of endosome size(GO:0051036)
0.2 1.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.2 1.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.2 1.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 1.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2 7.0 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.2 8.6 GO:0021884 forebrain neuron development(GO:0021884)
0.2 8.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.2 4.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 2.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.9 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 2.0 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 6.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 2.7 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1 10.0 GO:0000045 autophagosome assembly(GO:0000045)
0.1 0.5 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 3.8 GO:0010107 potassium ion import(GO:0010107)
0.1 1.3 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 3.0 GO:0048240 sperm capacitation(GO:0048240)
0.1 3.0 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 3.3 GO:0006379 mRNA cleavage(GO:0006379)
0.1 4.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 2.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 3.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 4.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 1.6 GO:0060992 response to fungicide(GO:0060992)
0.1 3.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.9 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.0 GO:0021794 thalamus development(GO:0021794)
0.1 0.9 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.1 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.1 GO:1900004 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 1.3 GO:0017085 response to insecticide(GO:0017085)
0.1 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 2.9 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 2.6 GO:0060021 palate development(GO:0060021)
0.0 5.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.4 GO:2000641 regulation of early endosome to late endosome transport(GO:2000641)
0.0 1.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 3.8 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.7 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 14.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0031103 axon regeneration(GO:0031103)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
1.3 2.7 GO:0030314 junctional membrane complex(GO:0030314)
1.2 8.6 GO:0001674 female germ cell nucleus(GO:0001674)
1.1 4.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.0 11.2 GO:0031010 ISWI-type complex(GO:0031010)
1.0 5.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0 2.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 3.0 GO:0072487 MSL complex(GO:0072487)
0.6 8.0 GO:0032426 stereocilium tip(GO:0032426)
0.6 7.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.5 3.2 GO:0005642 annulate lamellae(GO:0005642)
0.5 1.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.5 4.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 3.0 GO:0036128 CatSper complex(GO:0036128)
0.4 26.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.4 3.0 GO:0033010 paranodal junction(GO:0033010)
0.4 1.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.4 3.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 3.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 5.9 GO:0005839 proteasome core complex(GO:0005839)
0.2 2.5 GO:0032437 cuticular plate(GO:0032437)
0.2 4.4 GO:0016460 myosin II complex(GO:0016460)
0.2 2.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 2.9 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 1.2 GO:0070449 elongin complex(GO:0070449)
0.2 3.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 2.9 GO:0016528 sarcoplasm(GO:0016528)
0.2 2.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 4.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 4.8 GO:0030673 axolemma(GO:0030673)
0.2 1.2 GO:0005638 lamin filament(GO:0005638)
0.1 11.5 GO:0030315 T-tubule(GO:0030315)
0.1 4.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 7.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 5.3 GO:0034704 calcium channel complex(GO:0034704)
0.1 13.4 GO:0016605 PML body(GO:0016605)
0.1 6.6 GO:0060170 ciliary membrane(GO:0060170)
0.1 3.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 5.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 9.2 GO:0070469 respiratory chain(GO:0070469)
0.1 7.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.6 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 5.5 GO:0045095 keratin filament(GO:0045095)
0.1 1.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 2.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 5.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 3.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 3.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 4.7 GO:0072562 blood microparticle(GO:0072562)
0.0 7.4 GO:0043209 myelin sheath(GO:0043209)
0.0 4.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 7.2 GO:0005938 cell cortex(GO:0005938)
0.0 12.8 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 5.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 16.5 GO:0005739 mitochondrion(GO:0005739)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
2.6 7.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
1.8 7.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.8 7.3 GO:1904288 BAT3 complex binding(GO:1904288)
1.7 13.7 GO:0043237 laminin-1 binding(GO:0043237)
1.5 4.6 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.5 10.5 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
1.5 11.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.3 9.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.1 9.1 GO:0051525 NFAT protein binding(GO:0051525)
1.1 3.3 GO:0004827 proline-tRNA ligase activity(GO:0004827)
1.0 9.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
1.0 3.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.0 6.8 GO:1904047 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) S-adenosyl-L-methionine binding(GO:1904047)
1.0 2.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.8 6.1 GO:0005113 patched binding(GO:0005113)
0.7 2.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.6 6.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.6 3.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.6 12.9 GO:0043274 phospholipase binding(GO:0043274)
0.6 5.0 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.5 2.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.5 4.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 5.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.5 2.1 GO:0033149 FFAT motif binding(GO:0033149)
0.5 8.6 GO:0044548 S100 protein binding(GO:0044548)
0.4 3.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 5.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 4.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 5.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 1.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 7.0 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.3 9.3 GO:0030332 cyclin binding(GO:0030332)
0.3 0.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 3.9 GO:0051787 misfolded protein binding(GO:0051787)
0.2 11.4 GO:0043531 ADP binding(GO:0043531)
0.2 4.8 GO:0010181 FMN binding(GO:0010181)
0.2 1.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.2 2.0 GO:0009881 photoreceptor activity(GO:0009881)
0.2 5.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 1.1 GO:0004969 histamine receptor activity(GO:0004969)
0.2 4.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 3.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 2.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 5.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 4.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 2.7 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 5.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 3.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.3 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.3 GO:0008061 chitin binding(GO:0008061)
0.1 5.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 4.7 GO:0070888 E-box binding(GO:0070888)
0.1 10.6 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 3.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 2.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 5.0 GO:0051287 NAD binding(GO:0051287)
0.1 3.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 2.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 2.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 3.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.6 GO:0048029 monosaccharide binding(GO:0048029)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 1.4 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 11.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 3.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 6.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 2.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 14.9 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 6.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 4.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 10.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 4.7 ST GAQ PATHWAY G alpha q Pathway
0.2 4.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 7.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 10.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 4.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.8 PID P73PATHWAY p73 transcription factor network
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.8 14.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.5 8.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.4 8.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 3.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 9.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 6.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 3.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 2.0 REACTOME OPSINS Genes involved in Opsins
0.2 6.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 8.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 3.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 1.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 9.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 12.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 3.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 1.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 5.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 3.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 4.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 2.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 3.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 6.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 3.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 4.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway