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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxb3

Z-value: 0.57

Motif logo

Transcription factors associated with Hoxb3

Gene Symbol Gene ID Gene Info
ENSRNOG00000008313 homeo box B3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb3rn6_v1_chr10_+_84182118_84182118-0.063.1e-01Click!

Activity profile of Hoxb3 motif

Sorted Z-values of Hoxb3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_7058314 14.77 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr3_-_14229067 13.26 ENSRNOT00000025534
ENSRNOT00000092865
complement C5
chr2_+_54466280 12.82 ENSRNOT00000033112
complement C6
chr7_-_68549763 12.50 ENSRNOT00000078014
solute carrier family 16 member 7
chr17_-_43537293 9.98 ENSRNOT00000091749
solute carrier family 17 member 3
chr9_-_4978892 9.23 ENSRNOT00000015189
sulfotransferase family 1C member 3
chr2_-_158133861 9.10 ENSRNOT00000090700
ventricular zone expressed PH domain-containing 1
chr2_+_23289374 9.03 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr14_+_22517774 8.80 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr1_-_104024682 8.39 ENSRNOT00000056081
MAS-related GPR, member X1
chr2_-_191294374 8.37 ENSRNOT00000067469
similar to S100 calcium-binding protein, ventral prostate
chr20_-_14020007 8.18 ENSRNOT00000093521
gamma-glutamyltransferase 1
chr1_+_61786900 7.94 ENSRNOT00000090287

chr17_-_84247038 7.17 ENSRNOT00000068553
nebulette
chr12_-_19167015 7.17 ENSRNOT00000001797
gap junction protein, gamma 3
chr19_-_50220455 7.04 ENSRNOT00000079760
short chain dehydrogenase/reductase family 42E, member 1
chr2_+_252090669 6.97 ENSRNOT00000020656
lysophosphatidic acid receptor 3
chr1_-_241460868 6.88 ENSRNOT00000054776
similar to RIKEN cDNA 1700028P14
chr5_-_161981441 6.66 ENSRNOT00000020316
podoplanin
chr20_-_9855443 6.35 ENSRNOT00000090275
ENSRNOT00000066266
trefoil factor 3
chr1_-_189181901 6.32 ENSRNOT00000092022
glycoprotein 2
chr1_-_189182306 6.32 ENSRNOT00000021249
glycoprotein 2
chr11_-_61234944 5.97 ENSRNOT00000059680
cilia and flagella associated protein 44
chr7_-_76488216 5.91 ENSRNOT00000080024
neurocalcin delta
chr2_+_248398917 5.14 ENSRNOT00000045855
guanylate binding protein 1
chrX_+_33884499 5.01 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr18_-_69944632 4.84 ENSRNOT00000047271
mitogen-activated protein kinase 4
chr14_-_7863664 4.74 ENSRNOT00000061162
protein tyrosine phosphatase, non-receptor type 13
chr14_-_16903242 4.71 ENSRNOT00000003001
shroom family member 3
chr4_+_139670092 4.62 ENSRNOT00000008879
leucine rich repeat neuronal 1
chr12_-_24775891 4.45 ENSRNOT00000074851
Williams Beuren syndrome chromosome region 27
chr4_+_158088505 4.42 ENSRNOT00000026643
von Willebrand factor
chr14_+_22724399 4.28 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_-_60657712 4.13 ENSRNOT00000040348
retinoic acid induced 14
chr1_-_198104109 4.11 ENSRNOT00000026186
sulfotransferase family 1A member 1
chr4_-_165192647 4.05 ENSRNOT00000086461
killer cell lectin-like receptor, subfamily A, member 5
chr17_+_10137974 4.03 ENSRNOT00000031935
hexokinase 3
chr8_+_128027958 3.89 ENSRNOT00000045049
acetyl-Coenzyme A acyltransferase 1B
chrX_-_134866210 3.79 ENSRNOT00000005331
apelin
chr1_-_252808380 3.67 ENSRNOT00000025856
cholesterol 25-hydroxylase
chr3_-_79282493 3.53 ENSRNOT00000049832
protein tyrosine phosphatase, receptor type, J
chr12_+_24761210 3.48 ENSRNOT00000002003
claudin 4
chr9_-_30844199 3.33 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr17_+_10138810 3.28 ENSRNOT00000079850
hexokinase 3
chr14_+_48740190 3.27 ENSRNOT00000031638
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_21920651 3.27 ENSRNOT00000066211
transmembrane protein 243
chr8_+_13796021 3.18 ENSRNOT00000013927
V-set and transmembrane domain containing 5
chr1_-_189238776 3.18 ENSRNOT00000020817
protein disulfide isomerase-like, testis expressed
chr9_-_70449796 3.11 ENSRNOT00000086391
malate dehydrogenase 1B
chrX_-_6620722 3.09 ENSRNOT00000066674
monoamine oxidase A
chr14_+_76732650 3.08 ENSRNOT00000088197
cytokine-dependent hematopoietic cell linker
chrX_-_13279082 3.00 ENSRNOT00000051898
ENSRNOT00000060857
tetraspanin 7
chr3_+_128155069 2.92 ENSRNOT00000051184
ENSRNOT00000006389
phospholipase C beta 1
chr7_+_99609191 2.86 ENSRNOT00000012883
squalene epoxidase
chr9_+_98438439 2.86 ENSRNOT00000027220
selenocysteine lyase
chr5_-_147412705 2.73 ENSRNOT00000010688
similar to mKIAA1522 protein
chr9_+_20241062 2.70 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr4_-_88684415 2.67 ENSRNOT00000009001
similar to 40S ribosomal protein S7 (S8)
chr19_-_42180362 2.67 ENSRNOT00000089515
polyamine modulated factor 1 binding protein 1
chr7_+_117456039 2.64 ENSRNOT00000051754
maestro heat-like repeat family member 1
chr10_+_103395511 2.56 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr1_+_229100752 2.48 ENSRNOT00000074881
similar to olfactory receptor 1442
chr1_-_276228574 2.46 ENSRNOT00000021746
guanylate cyclase 2G
chr9_+_117795132 2.46 ENSRNOT00000086943
A-kinase anchor inhibitor 1
chr11_-_81757813 2.46 ENSRNOT00000002462
DnaJ heat shock protein family (Hsp40) member B11
chr10_+_89484468 2.44 ENSRNOT00000035523
transmembrane protein 106A
chr15_+_87722221 2.36 ENSRNOT00000082688
sciellin
chr7_+_59200918 2.30 ENSRNOT00000085073
protein tyrosine phosphatase, receptor type, R
chr14_+_96499520 2.27 ENSRNOT00000074692

chr11_+_74057361 2.22 ENSRNOT00000048746
carboxypeptidase N subunit 2
chr11_-_14304603 2.20 ENSRNOT00000040202
ENSRNOT00000082143
SAM domain, SH3 domain and nuclear localization signals, 1
chr4_-_157304653 2.15 ENSRNOT00000051613
leucine rich repeat containing 23
chr18_+_3705916 2.07 ENSRNOT00000092846
laminin subunit alpha 3
chr4_+_56981283 2.07 ENSRNOT00000010989
tetraspanin 33
chr4_-_165317573 2.06 ENSRNOT00000087529
ENSRNOT00000080017
killer cell lectin-like receptor, subfamily A, member 5
chr17_+_87274944 1.99 ENSRNOT00000073718
enhancer trap locus 4
chr13_+_90943255 1.96 ENSRNOT00000011539
V-set and immunoglobulin domain containing 8
chr17_+_76002275 1.94 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr8_-_113937097 1.92 ENSRNOT00000046816
NIMA-related kinase 11
chr5_+_28485619 1.92 ENSRNOT00000093341
ENSRNOT00000093129
uncharacterized LOC100912373
chr1_-_184188911 1.88 ENSRNOT00000055124
ENSRNOT00000014948
calcitonin-related polypeptide alpha
chr8_+_116318963 1.86 ENSRNOT00000036556
tumor suppressor candidate 2
chr10_-_34301197 1.76 ENSRNOT00000044667
olfactory receptor 1383
chr3_-_150603082 1.76 ENSRNOT00000024310
adenosylhomocysteinase
chr14_-_114692764 1.75 ENSRNOT00000008210
spectrin, beta, non-erythrocytic 1
chr10_-_34333305 1.73 ENSRNOT00000071365
olfactory receptor gene Olr1384
chr9_-_44419998 1.72 ENSRNOT00000091397
ENSRNOT00000083747
testis specific 10
chr4_+_155009479 1.71 ENSRNOT00000070906

chr18_+_4084228 1.63 ENSRNOT00000071392
calcium binding tyrosine phosphorylation regulated
chr10_-_34361212 1.60 ENSRNOT00000072557
olfactory receptor 1385
chr5_-_151459037 1.60 ENSRNOT00000064472
ENSRNOT00000087836
synaptotagmin-like 1
chr8_+_2604962 1.59 ENSRNOT00000009993
caspase 1
chr16_+_54332660 1.55 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr5_+_146656049 1.55 ENSRNOT00000036029
CUB and Sushi multiple domains 2
chr6_+_104291071 1.52 ENSRNOT00000006798
solute carrier family 39, member 9
chr18_-_25997555 1.52 ENSRNOT00000027755
StAR-related lipid transfer domain containing 4
chr5_-_133959447 1.46 ENSRNOT00000011985
cytochrome P450, family 4, subfamily x, polypeptide 1
chr10_+_36517169 1.45 ENSRNOT00000040534
olfactory receptor 1408
chr5_-_64850427 1.44 ENSRNOT00000008883
transmembrane protein 246
chr10_+_47765432 1.43 ENSRNOT00000078231
microfibril-associated glycoprotein 4-like
chr4_-_165026414 1.38 ENSRNOT00000071421
killer cell lectin-like receptor, subfamily A, member 1
chr2_+_23385183 1.36 ENSRNOT00000014860
arylsulfatase B
chr1_+_169208988 1.34 ENSRNOT00000050606
olfactory receptor 140
chr20_-_13994794 1.34 ENSRNOT00000093466
gamma-glutamyltransferase 5
chr13_+_83681322 1.33 ENSRNOT00000004206
mitochondrial pyruvate carrier 2
chr4_+_171748273 1.32 ENSRNOT00000009998
deoxyribose-phosphate aldolase
chr1_+_252284464 1.32 ENSRNOT00000027969
lipase F, gastric type
chr3_-_120076788 1.26 ENSRNOT00000047158
potassium voltage-gated channel interacting protein 3
chr18_+_30581530 1.25 ENSRNOT00000048166
protocadherin beta 20
chr11_+_81757983 1.25 ENSRNOT00000088503
TBCC domain containing 1
chr10_+_36590325 1.25 ENSRNOT00000085203
zinc finger protein 354A
chr4_-_132296413 1.24 ENSRNOT00000052326
similar to macrophage migration inhibitory factor
chr10_+_44506098 1.24 ENSRNOT00000078135
similar to olfactory receptor Olr1448
chr10_+_96639924 1.23 ENSRNOT00000004756
apolipoprotein H
chr20_-_30947484 1.22 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr3_+_75970593 1.19 ENSRNOT00000075834
olfactory receptor 592
chr6_-_105261549 1.18 ENSRNOT00000009122
synaptojanin 2 binding protein
chr7_-_44121130 1.18 ENSRNOT00000005706
neurotensin
chr16_+_73615949 1.16 ENSRNOT00000024392
glycerol-3-phosphate acyltransferase 4
chr20_-_29199224 1.14 ENSRNOT00000071477
mitochondrial calcium uniporter
chr19_+_653510 1.10 ENSRNOT00000048221
NEDD8 activating enzyme E1 subunit 1
chr7_-_83670356 1.05 ENSRNOT00000005584
syntabulin
chr20_+_31761405 1.05 ENSRNOT00000000661
neurogenin 3
chr17_+_9797907 1.05 ENSRNOT00000021638
lectin, mannose-binding 2
chr4_+_148476943 1.01 ENSRNOT00000017689
olfactory receptor 823
chr16_-_29936307 1.01 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr10_-_88670430 0.99 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr1_+_190200324 0.95 ENSRNOT00000001933
ATP-binding cassette, subfamily A (ABC1), member 16
chr14_-_45859908 0.95 ENSRNOT00000086994
phosphoglucomutase 2
chr1_-_227457629 0.94 ENSRNOT00000035910
ENSRNOT00000073770
membrane spanning 4-domains A5
chr14_-_2032593 0.94 ENSRNOT00000000037
fibroblast growth factor receptor-like 1
chr6_-_3355339 0.94 ENSRNOT00000084602
mitogen-activated protein kinase kinase kinase kinase 3
chr6_-_108920767 0.90 ENSRNOT00000006704
prospero homeobox 2
chr14_+_2892753 0.89 ENSRNOT00000061630
ecotropic viral integration site 5
chr4_+_71836677 0.88 ENSRNOT00000024048
taste receptor, type 2, member 126
chr20_-_1099336 0.87 ENSRNOT00000071766
olfactory receptor-like protein-like
chr3_-_77494108 0.86 ENSRNOT00000047726
olfactory receptor 662
chr2_-_46544457 0.86 ENSRNOT00000015680
follistatin
chr10_+_34402482 0.86 ENSRNOT00000072317
putative olfactory receptor
chr10_-_60032218 0.85 ENSRNOT00000072328
olfactory receptor 1481
chr17_+_81280898 0.85 ENSRNOT00000057785
transmembrane protein 236
chr16_-_75241303 0.84 ENSRNOT00000058056
defensin beta 2
chr2_+_85305225 0.80 ENSRNOT00000015904
taste receptor, type 2, member 119
chr5_-_151473750 0.78 ENSRNOT00000011357
transmembrane protein 222
chr1_-_78686952 0.77 ENSRNOT00000047079
similar to Macrophage migration inhibitory factor (MIF) (Phenylpyruvate tautomerase) (Glycosylation-inhibiting factor) (GIF) (Delayed early response protein 6) (DER6)
chr2_+_148765412 0.75 ENSRNOT00000018248
ENSRNOT00000084662
selenoprotein T
chr12_-_35979193 0.75 ENSRNOT00000071104
transmembrane protein 132B
chr7_-_83701447 0.75 ENSRNOT00000088893

chr10_-_44471915 0.73 ENSRNOT00000089901
olfactory receptor 1440
chr8_+_77088469 0.73 ENSRNOT00000090317
predicted gene 10642
chr8_-_59239954 0.72 ENSRNOT00000016104
acyl-CoA synthetase bubblegum family member 1
chr1_-_167971151 0.72 ENSRNOT00000043023
olfactory receptor 53
chr4_-_174180729 0.72 ENSRNOT00000011376
phospholipase C, zeta 1
chr13_+_82438697 0.71 ENSRNOT00000003759
selectin P
chr2_-_187786700 0.71 ENSRNOT00000092257
ENSRNOT00000092612
ENSRNOT00000068360
solute carrier family 25, member 44
chr10_+_5199226 0.70 ENSRNOT00000003544
dexamethasone-induced transcript
chr8_+_128792707 0.70 ENSRNOT00000083329
solute carrier family 25, member 38
chr12_+_22727335 0.69 ENSRNOT00000077293
zinc finger, HIT-type containing 1
chr17_-_22678253 0.69 ENSRNOT00000083122
LRRGT00112-like
chr1_-_149675443 0.68 ENSRNOT00000086084
olfactory receptor 294
chr1_+_169153297 0.68 ENSRNOT00000052078
olfactory receptor 137
chr20_-_3344286 0.68 ENSRNOT00000091505
protein phosphatase 1, regulatory subunit 10
chr5_+_14890408 0.67 ENSRNOT00000033116
SRY box 17
chr11_+_43465370 0.67 ENSRNOT00000039939
olfactory receptor 1547
chr4_+_52235811 0.65 ENSRNOT00000060478
hyaluronoglucosaminidase 5
chr4_+_148782479 0.65 ENSRNOT00000018133
similar to hypothetical protein MGC6835
chr3_-_44501115 0.65 ENSRNOT00000087071
activin A receptor type 1
chr1_+_169182969 0.63 ENSRNOT00000040131
olfactory receptor 139
chr5_+_187312 0.62 ENSRNOT00000030857
zinc finger protein 120-like
chr6_+_104291340 0.59 ENSRNOT00000089313
solute carrier family 39, member 9
chr10_+_44679832 0.59 ENSRNOT00000044332
olfactory receptor 1450
chr16_-_75107931 0.58 ENSRNOT00000058066
defensin beta 15
chr2_+_185846232 0.58 ENSRNOT00000023418
LPS responsive beige-like anchor protein
chr6_-_103807838 0.57 ENSRNOT00000058328

chr18_+_16544508 0.56 ENSRNOT00000020601
elongator acetyltransferase complex subunit 2
chr20_-_36061477 0.56 ENSRNOT00000038249
similar to hypothetical protein
chr1_-_150101177 0.55 ENSRNOT00000042931
olfactory receptor 24
chr3_-_164964702 0.55 ENSRNOT00000014595
activity-dependent neuroprotector homeobox
chr11_-_1437732 0.52 ENSRNOT00000037345
casein kinase 2, alpha prime interacting protein
chr1_-_64147251 0.51 ENSRNOT00000088502
CCR4-NOT transcription complex, subunit 3
chr20_+_44680449 0.50 ENSRNOT00000000728
Traf3 interacting protein 2
chr4_-_82141385 0.50 ENSRNOT00000008447
homeobox A3
chrX_+_14019961 0.49 ENSRNOT00000004785
synaptotagmin-like 5
chr1_-_14117021 0.49 ENSRNOT00000004344
similar to hypothetical protein 4933423E17
chr13_+_70174936 0.48 ENSRNOT00000064068
ENSRNOT00000079861
ENSRNOT00000092562
actin related protein 2/3 complex, subunit 5
chr15_+_33885106 0.47 ENSRNOT00000024483
dehydrogenase/reductase 2
chr10_-_41491554 0.47 ENSRNOT00000035759
uncharacterized LOC102552619
chr13_+_56096834 0.47 ENSRNOT00000035129
DENN domain containing 1B
chr17_+_11856525 0.45 ENSRNOT00000014546
serine palmitoyltransferase, long chain base subunit 1
chr1_-_167732783 0.43 ENSRNOT00000024965
olfactory receptor 44
chr6_-_108660063 0.43 ENSRNOT00000006240
apoptosis resistant E3 ubiquitin protein ligase 1
chr3_-_102672294 0.41 ENSRNOT00000030909
olfactory receptor 760
chr10_+_44650570 0.40 ENSRNOT00000047671
olfactory receptor 1449
chr1_+_75326217 0.40 ENSRNOT00000044964
vomeronasal 1 receptor 62
chr5_-_59266293 0.40 ENSRNOT00000050490
olfactory receptor 836
chr10_-_5344121 0.40 ENSRNOT00000003479
nucleotide binding protein 1
chr20_-_35342 0.40 ENSRNOT00000048277
olfactory receptor 2B11-like
chr3_-_103152122 0.40 ENSRNOT00000045743
olfactory receptor 781
chr1_-_198450047 0.39 ENSRNOT00000027360
major vault protein
chr8_-_14156656 0.38 ENSRNOT00000089364
deuterosome assembly protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.8 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
3.7 14.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
3.2 12.6 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
3.0 9.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
2.8 13.8 GO:1901475 pyruvate transmembrane transport(GO:1901475)
2.4 7.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
2.2 13.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.0 8.2 GO:0031179 peptide modification(GO:0031179)
1.1 10.9 GO:0010572 positive regulation of platelet activation(GO:0010572)
1.0 2.9 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-12(GO:0071349) cellular response to interleukin-15(GO:0071350) regulation of monocyte extravasation(GO:2000437)
0.9 3.8 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.9 10.0 GO:0015747 urate transport(GO:0015747)
0.9 5.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.6 1.9 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.6 1.9 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.6 7.3 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.6 4.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.6 2.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.5 4.4 GO:0070417 cellular response to cold(GO:0070417)
0.4 3.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.4 7.0 GO:0032060 bleb assembly(GO:0032060)
0.4 2.9 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.4 1.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 1.2 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.4 1.5 GO:0070859 lipid transport involved in lipid storage(GO:0010877) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 4.4 GO:0006108 malate metabolic process(GO:0006108)
0.4 3.7 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 1.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 6.0 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.3 1.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.3 1.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.2 GO:0097332 response to antipsychotic drug(GO:0097332)
0.2 3.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 0.7 GO:0061010 inner cell mass cellular morphogenesis(GO:0001828) endodermal cell fate determination(GO:0007493) gall bladder development(GO:0061010)
0.2 1.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.6 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
0.2 1.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 2.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 0.5 GO:0010159 specification of organ position(GO:0010159)
0.2 1.8 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.2 0.5 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.9 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.7 GO:0001552 ovarian follicle atresia(GO:0001552)
0.1 0.7 GO:0036233 glycine import(GO:0036233)
0.1 3.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.3 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.9 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.4 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 1.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.0 GO:0060290 transdifferentiation(GO:0060290)
0.1 0.7 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.7 GO:0007343 egg activation(GO:0007343)
0.1 0.9 GO:0060539 diaphragm development(GO:0060539)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 1.8 GO:0016556 mRNA modification(GO:0016556)
0.1 2.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.5 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.1 0.5 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835) gas homeostasis(GO:0033483)
0.1 1.4 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 4.7 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 1.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 2.5 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 2.2 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.1 2.9 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 7.2 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 4.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.3 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 5.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 6.3 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.4 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.5 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 4.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 1.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 3.5 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.7 GO:0043486 histone exchange(GO:0043486)
0.0 2.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.5 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 1.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.8 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 2.1 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 0.9 GO:0006006 glucose metabolic process(GO:0006006)
0.0 3.4 GO:0006631 fatty acid metabolic process(GO:0006631)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 26.1 GO:0005579 membrane attack complex(GO:0005579)
1.3 5.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.7 4.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.1 GO:0005608 laminin-3 complex(GO:0005608)
0.3 7.2 GO:0005922 connexon complex(GO:0005922)
0.3 5.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.6 GO:0072558 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.3 2.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.1 GO:1990246 uniplex complex(GO:1990246)
0.2 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.8 GO:0008091 spectrin(GO:0008091) cuticular plate(GO:0032437)
0.1 3.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 1.1 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.2 GO:0042627 chylomicron(GO:0042627)
0.1 1.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.5 GO:0001772 immunological synapse(GO:0001772)
0.1 6.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 7.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 3.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 13.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 4.1 GO:0001650 fibrillar center(GO:0001650)
0.0 4.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.2 GO:0072562 blood microparticle(GO:0072562)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)
0.0 7.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 13.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.8 GO:0030027 lamellipodium(GO:0030027)
0.0 10.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 4.0 GO:0043679 axon terminus(GO:0043679)
0.0 0.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 1.7 GO:0031514 motile cilium(GO:0031514)
0.0 3.8 GO:0030424 axon(GO:0030424)
0.0 2.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.6 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
4.1 4.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
2.8 13.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
2.3 9.2 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
1.7 7.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.6 9.5 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
1.3 5.1 GO:0019002 GMP binding(GO:0019002)
1.2 7.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.0 10.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) efflux transmembrane transporter activity(GO:0015562) salt transmembrane transporter activity(GO:1901702)
0.9 9.0 GO:0005542 folic acid binding(GO:0005542)
0.8 6.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.8 3.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.6 3.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.5 14.8 GO:0019825 oxygen binding(GO:0019825)
0.5 3.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.4 1.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 13.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 1.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 7.2 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.1 GO:0015292 uniporter activity(GO:0015292)
0.3 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 3.5 GO:0070097 delta-catenin binding(GO:0070097)
0.3 5.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 2.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 3.1 GO:0051378 serotonin binding(GO:0051378)
0.2 5.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 1.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.2 0.7 GO:0042806 fucose binding(GO:0042806)
0.2 4.8 GO:0004707 MAP kinase activity(GO:0004707)
0.2 3.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 1.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 3.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 4.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 12.6 GO:0003823 antigen binding(GO:0003823)
0.1 3.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 3.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.5 GO:0048185 activin binding(GO:0048185)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 2.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 2.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 1.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 3.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 2.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.5 GO:0070330 aromatase activity(GO:0070330)
0.1 0.8 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 1.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 4.7 GO:0051015 actin filament binding(GO:0051015)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 7.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 4.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 3.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 7.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 3.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 2.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 14.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.9 12.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 26.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 5.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 9.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 4.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 4.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 2.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 4.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 3.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.1 7.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 8.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall