Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Hoxb6

Z-value: 0.46

Motif logo

logo of

Transcription factors associated with Hoxb6

Gene Symbol Gene ID Gene Info
Hoxb6
ENSRNOG00000007823 homeo box B6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb6rn6_v1_chr10_+_84147836_84147836-0.411.2e-14Click!

Activity profile of Hoxb6 motif

Sorted Z-values of Hoxb6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_85974644 13.52 ENSRNOT00000006098
ENSRNOT00000082974
Cacnb1
calcium voltage-gated channel auxiliary subunit beta 1
chr17_-_43614844 11.91 ENSRNOT00000023054
Hist1h1a
histone cluster 1 H1 family member a
chr6_-_95934296 9.54 ENSRNOT00000034338
Six1
SIX homeobox 1
chr9_-_63291350 7.05 ENSRNOT00000058831
Hsfy2
heat shock transcription factor, Y linked 2
chr11_-_45124423 6.71 ENSRNOT00000046383
Filip1l
filamin A interacting protein 1-like
chr18_-_786674 6.68 ENSRNOT00000021955
Cetn1
centrin 1
chr1_-_197821936 6.24 ENSRNOT00000055027
Cd19
CD19 molecule
chr14_+_39368530 5.95 ENSRNOT00000084367
Cox7b2
cytochrome c oxidase subunit 7B2
chr3_+_110855000 5.68 ENSRNOT00000081613
Knl1
kinetochore scaffold 1
chr13_+_78886163 4.83 ENSRNOT00000059266
ENSRNOT00000076513
Cenpl
centromere protein L
chr1_-_222182721 4.71 ENSRNOT00000078008
Tex40
testis expressed 40
chr14_+_91557601 4.69 ENSRNOT00000038733
RGD1309870
hypothetical LOC289778
chr6_+_96007805 4.30 ENSRNOT00000010163
Mnat1
MNAT CDK-activating kinase assembly factor 1
chr13_-_91776397 4.27 ENSRNOT00000073147
Mptx1
mucosal pentraxin 1
chr9_-_42839837 4.22 ENSRNOT00000038610
Neurl3
neuralized E3 ubiquitin protein ligase 3
chr13_-_61591139 4.05 ENSRNOT00000005324
Rgs18
regulator of G-protein signaling 18
chr5_-_156689415 3.91 ENSRNOT00000083474
Pink1
PTEN induced putative kinase 1
chr5_+_48303366 3.69 ENSRNOT00000009973
Gabrr2
gamma-aminobutyric acid type A receptor rho 2 subunit
chr10_-_56403188 3.41 ENSRNOT00000019947
Chrnb1
cholinergic receptor nicotinic beta 1 subunit
chr7_+_35773928 3.17 ENSRNOT00000034639
Cep83
centrosomal protein 83
chr11_+_53140599 2.94 ENSRNOT00000083438
Bbx
BBX, HMG-box containing
chr2_-_203350736 2.93 ENSRNOT00000090115
ENSRNOT00000084516
Ttf2
transcription termination factor 2
chr19_-_37427989 2.91 ENSRNOT00000022863
Tppp3
tubulin polymerization-promoting protein family member 3
chr4_-_177039677 2.57 ENSRNOT00000055538
ENSRNOT00000075667
RGD1561551
similar to Hypothetical protein MGC75664
chr9_+_45605552 2.56 ENSRNOT00000059587
NMS
neuromedin S
chr4_-_28437676 2.49 ENSRNOT00000012995
Hepacam2
HEPACAM family member 2
chr5_+_8957405 2.45 ENSRNOT00000088164
Tcf24
transcription factor 24
chr7_+_120923274 2.40 ENSRNOT00000049247
Gtpbp1
GTP binding protein 1
chr1_-_246010594 2.32 ENSRNOT00000023762
Rfx3
regulatory factor X3
chr15_-_28935269 2.20 ENSRNOT00000060427
Olr1645
olfactory receptor 1645
chrX_-_111102464 2.10 ENSRNOT00000084176
Ripply1
ripply transcriptional repressor 1
chr15_+_28439317 2.06 ENSRNOT00000060519
LOC690384
similar to ribosomal protein L31
chr1_-_1889236 2.06 ENSRNOT00000087944
AABR07000159.2

chr14_+_3882398 2.05 ENSRNOT00000033794
Hfm1
HFM1, ATP-dependent DNA helicase homolog
chr3_+_110508403 2.02 ENSRNOT00000079959
AABR07053500.2

chr7_+_125288081 1.94 ENSRNOT00000085216
Parvg
parvin, gamma
chr9_+_53440272 1.79 ENSRNOT00000059159
LOC685203
hypothetical protein LOC685203
chr17_+_69960160 1.70 ENSRNOT00000023887
Ucn3
urocortin 3
chr4_-_164691405 1.64 ENSRNOT00000090979
ENSRNOT00000091932
ENSRNOT00000078219
Ly49s4
Ly49i2
Ly49 stimulatory receptor 4
Ly49 inhibitory receptor 2
chr1_+_178039063 1.12 ENSRNOT00000046313
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr4_+_1841955 1.11 ENSRNOT00000019271
Olr1096
olfactory receptor 1096
chr5_+_169898302 0.95 ENSRNOT00000087911
AABR07050561.1

chr4_-_82133605 0.93 ENSRNOT00000008023
NEWGENE_2813
homeobox A2
chr3_-_103128243 0.86 ENSRNOT00000046310
Olr779
olfactory receptor 779
chrX_-_45284341 0.84 ENSRNOT00000045436
Obp1f
odorant binding protein I f
chr2_-_194875962 0.81 ENSRNOT00000085431
RGD1566337
similar to TDPOZ2
chr17_-_27451832 0.76 ENSRNOT00000084417
Riok1
RIO kinase 1
chr3_-_103400272 0.71 ENSRNOT00000046527
Olr790
olfactory receptor 790
chr3_+_102723402 0.67 ENSRNOT00000040298
Olr765
olfactory receptor 765
chr9_-_88748866 0.60 ENSRNOT00000071906
Rpl30l1
ribosomal protein L30-like 1
chr3_+_103657115 0.56 ENSRNOT00000075514
Olr796
olfactory receptor 796
chrX_-_83864150 0.56 ENSRNOT00000073734
Obp1f
odorant binding protein I f
chr9_-_52238564 0.55 ENSRNOT00000005073
Col5a2
collagen type V alpha 2 chain
chr3_-_103203299 0.53 ENSRNOT00000047208
Olr783
olfactory receptor 783
chr8_+_42296303 0.52 ENSRNOT00000044272
Olr1238
olfactory receptor 1238
chr1_+_79474809 0.50 ENSRNOT00000044927
Ceacam12
carcinoembryonic antigen-related cell adhesion molecule 12
chr5_+_160825419 0.46 ENSRNOT00000080134
AABR07050317.1

chr3_-_103345333 0.44 ENSRNOT00000071479
LOC100909692
olfactory receptor 4F3/4F16/4F29-like
chr1_+_65292386 0.39 ENSRNOT00000029893
AABR07002044.1

chr8_+_41911004 0.34 ENSRNOT00000071217
LOC100912067
olfactory receptor 143-like
chr1_-_172616633 0.32 ENSRNOT00000012919
Olr262
olfactory receptor 262
chr3_-_75576520 0.26 ENSRNOT00000083330
Olr567
olfactory receptor 567
chr11_+_43465370 0.23 ENSRNOT00000039939
Olr1547
olfactory receptor 1547
chr13_-_98023829 0.22 ENSRNOT00000075426
Kif28p
kinesin family member 28, pseudogene
chr1_+_229480184 0.20 ENSRNOT00000044115
Olr387
olfactory receptor 387
chr2_-_236149971 0.19 ENSRNOT00000089472
AABR07013412.1

chr3_+_75999481 0.17 ENSRNOT00000074642
Olr595
olfactory receptor 595

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:2000729 response to 3,3',5-triiodo-L-thyronine(GO:1905242) cellular response to 3,3',5-triiodo-L-thyronine(GO:1905243) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.8 3.9 GO:1902958 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.8 2.3 GO:0002071 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.4 6.2 GO:0006968 cellular defense response(GO:0006968)
0.4 3.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.4 5.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.3 4.3 GO:0007512 adult heart development(GO:0007512)
0.3 13.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 3.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.2 11.9 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 2.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 2.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 2.6 GO:0045475 locomotor rhythm(GO:0045475)
0.1 6.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 2.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 0.8 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 1.7 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 5.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 4.0 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 2.9 GO:0046785 microtubule polymerization(GO:0046785)
0.0 2.9 GO:0060348 bone development(GO:0060348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 11.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.3 5.9 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 13.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 3.8 GO:0005675 holo TFIIH complex(GO:0005675)
0.2 3.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 2.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 3.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 3.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 6.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.7 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.0 5.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 9.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.5 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.1 4.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.7 13.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 1.7 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.4 3.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 9.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 3.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 3.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 5.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 11.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 2.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 6.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 4.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 3.0 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 3.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 11.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 14.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 3.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 6.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 3.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 5.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events