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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Irx5

Z-value: 0.90

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Transcription factors associated with Irx5

Gene Symbol Gene ID Gene Info
Irx5
ENSRNOG00000011180 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irx5rn6_v1_chr19_+_16415636_16415636-0.181.3e-03Click!

Activity profile of Irx5 motif

Sorted Z-values of Irx5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_189328246 42.63 ENSRNOT00000084260
Acsm1
acyl-CoA synthetase medium-chain family member 1
chr7_-_123655896 42.09 ENSRNOT00000012413
Cyp2d2
cytochrome P450, family 2, subfamily d, polypeptide 2
chr12_-_29743705 28.63 ENSRNOT00000001185
Caln1
calneuron 1
chr2_-_235161263 28.39 ENSRNOT00000080235
LOC103691699
uncharacterized LOC103691699
chr1_-_259287684 28.35 ENSRNOT00000054724
Cyp2c22
cytochrome P450, family 2, subfamily c, polypeptide 22
chr13_-_56763981 27.76 ENSRNOT00000087916
LOC100361907
complement factor H-related protein B
chr3_+_40038336 27.64 ENSRNOT00000048804
Galnt13
polypeptide N-acetylgalactosaminyltransferase 13
chr7_-_123621102 27.22 ENSRNOT00000046024
Cyp2d5
cytochrome P450, family 2, subfamily d, polypeptide 5
chr7_-_123630045 25.65 ENSRNOT00000050002
Cyp2d1
cytochrome P450, family 2, subfamily d, polypeptide 1
chr7_-_123638702 24.55 ENSRNOT00000082473
ENSRNOT00000044470
ENSRNOT00000092017
Cyp2d1
cytochrome P450, family 2, subfamily d, polypeptide 1
chr5_-_166116516 22.69 ENSRNOT00000079919
ENSRNOT00000080888
Kif1b
kinesin family member 1B
chr17_-_10439691 20.74 ENSRNOT00000024151
Cdhr2
cadherin-related family member 2
chr8_+_33514042 20.15 ENSRNOT00000081614
ENSRNOT00000081525
Kcnj1
potassium voltage-gated channel subfamily J member 1
chr3_+_134440195 19.41 ENSRNOT00000072928
AABR07054000.1

chr16_+_50181316 17.51 ENSRNOT00000077662
F11
coagulation factor XI
chr2_+_251200686 15.98 ENSRNOT00000019210
Col24a1
collagen type XXIV alpha 1 chain
chr1_+_80141630 15.04 ENSRNOT00000029552
Opa3
optic atrophy 3
chr4_-_52350624 14.68 ENSRNOT00000060476
Tmem229a
transmembrane protein 229A
chr7_+_26522314 13.16 ENSRNOT00000011572
Slc41a2
solute carrier family 41 member 2
chr8_+_5676665 12.14 ENSRNOT00000012310
Mmp3
matrix metallopeptidase 3
chr14_-_46153212 11.82 ENSRNOT00000079269
Nwd2
NACHT and WD repeat domain containing 2
chr8_+_57936650 11.62 ENSRNOT00000089686
Exph5
exophilin 5
chr2_+_228544418 10.09 ENSRNOT00000013030
Tram1l1
translocation associated membrane protein 1-like 1
chr3_+_112916217 9.56 ENSRNOT00000030065
Tmem62
transmembrane protein 62
chr1_+_268189277 9.14 ENSRNOT00000065001
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr7_+_139685573 8.41 ENSRNOT00000088376
Pfkm
phosphofructokinase, muscle
chr6_+_107999846 8.25 ENSRNOT00000058095
Ptgr2
prostaglandin reductase 2
chr1_-_100969560 8.06 ENSRNOT00000035908
Cpt1c
carnitine palmitoyltransferase 1c
chr1_+_261497059 7.60 ENSRNOT00000020390
Golga7b
golgin A7 family, member B
chr8_+_42511520 7.59 ENSRNOT00000042974
Olr1259
olfactory receptor 1259
chr16_+_25773602 7.42 ENSRNOT00000047750
Gapdh-ps2
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr20_-_422464 7.39 ENSRNOT00000051646
Olr1673
olfactory receptor 1673
chr9_+_65013862 7.18 ENSRNOT00000092906
ENSRNOT00000081146
Aox3
aldehyde oxidase 3
chr13_+_57243877 7.11 ENSRNOT00000083693
Kcnt2
potassium sodium-activated channel subfamily T member 2
chr10_-_12818137 7.08 ENSRNOT00000060972
Olr1382
olfactory receptor 1382
chr7_-_124999137 7.05 ENSRNOT00000039228
Pnpla5
patatin-like phospholipase domain containing 5
chr2_+_208738132 6.64 ENSRNOT00000023972
AABR07012795.1

chr18_-_28017925 6.60 ENSRNOT00000075420
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr4_+_29978739 6.58 ENSRNOT00000011756
Ppp1r9a
protein phosphatase 1, regulatory subunit 9A
chr2_+_104744461 6.57 ENSRNOT00000016083
ENSRNOT00000082627
Cp
ceruloplasmin
chr5_+_122390522 6.47 ENSRNOT00000064567
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr10_-_36336628 6.38 ENSRNOT00000030035
Zfp879
zinc finger protein 879
chr11_-_45688560 6.01 ENSRNOT00000081508
Olr1536
olfactory receptor 1536
chr10_+_55997614 5.85 ENSRNOT00000013071
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr3_+_77018186 5.57 ENSRNOT00000074443
Olr646
olfactory receptor 646
chr17_+_76359022 5.36 ENSRNOT00000039621
ENSRNOT00000092481
Sec61a2
Sec61 translocon alpha 2 subunit
chr4_-_142970245 5.13 ENSRNOT00000067815
AC112018.1

chr3_-_78571715 4.83 ENSRNOT00000044992
Olr712
olfactory receptor 712
chrM_+_3904 4.83 ENSRNOT00000040993
Mt-nd2
mitochondrially encoded NADH dehydrogenase 2
chr3_-_103217528 4.76 ENSRNOT00000074456
Olr784
olfactory receptor 784
chr4_+_21462779 4.70 ENSRNOT00000089747
Grm3
glutamate metabotropic receptor 3
chr1_-_276228574 4.65 ENSRNOT00000021746
Gucy2g
guanylate cyclase 2G
chr4_-_103403976 4.58 ENSRNOT00000088153
AABR07061057.3

chrX_-_119162518 4.48 ENSRNOT00000073176
LOC103694506
ubiquitin-conjugating enzyme E2 W
chr1_+_68528976 4.46 ENSRNOT00000072292
Vom1r27
vomeronasal 1 receptor 27
chr10_-_52290657 4.32 ENSRNOT00000005293
Map2k4
mitogen activated protein kinase kinase 4
chr1_+_75194565 4.28 ENSRNOT00000050604
Vom1r60
vomeronasal 1 receptor 60
chr1_-_60634546 4.17 ENSRNOT00000051451
Vom1r15
vomeronasal 1 receptor 15
chrX_-_37003642 4.09 ENSRNOT00000040770
ENSRNOT00000058834
ENSRNOT00000058833
Adgrg2
adhesion G protein-coupled receptor G2
chr1_+_168196862 4.06 ENSRNOT00000021006
Olr74
olfactory receptor 74
chr1_+_229349133 4.02 ENSRNOT00000075498
LOC100910906
serine protease inhibitor Kazal-type 14-like
chr1_+_201901342 4.01 ENSRNOT00000036657
RGD1559891
similar to synaptonemal complex protein 3
chr2_-_259382765 3.99 ENSRNOT00000091407
St6galnac3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr10_-_12674077 3.85 ENSRNOT00000041353
Olr1376
olfactory receptor 1376
chr19_+_51317425 3.83 ENSRNOT00000019298
Cdh13
cadherin 13
chr1_+_157920786 3.77 ENSRNOT00000014284
Fam181b
family with sequence similarity 181, member B
chr3_-_78595778 3.73 ENSRNOT00000084255
Olr715
olfactory receptor 715
chr1_-_230687157 3.71 ENSRNOT00000048193
Olr380
olfactory receptor 380
chr1_+_167786337 3.67 ENSRNOT00000024945
Olr48
olfactory receptor 48
chr2_-_149754776 3.63 ENSRNOT00000035057
RGD1559622
similar to hypothetical protein C130079G13
chr5_+_69305190 3.55 ENSRNOT00000074390
LOC108348075
olfactory receptor 13C3-like
chr3_-_2845593 3.54 ENSRNOT00000067479
Tmem141
transmembrane protein 141
chr3_-_73543088 3.51 ENSRNOT00000012912
Olr485
olfactory receptor 485
chr9_-_92524739 3.38 ENSRNOT00000089889
Slc16a14
solute carrier family 16, member 14
chr4_+_72603242 3.34 ENSRNOT00000007229
Olr818
olfactory receptor 818
chr1_-_103811148 3.27 ENSRNOT00000030162
Mrgprx2l
MAS-related G protein-coupled receptor, member X2-like
chr7_-_6803318 3.21 ENSRNOT00000084203
Olr954
olfactory receptor 954
chr3_-_78790691 3.08 ENSRNOT00000008750
Olr724
olfactory receptor 724
chr3_+_93968855 2.99 ENSRNOT00000014478
Fbxo3
F-box protein 3
chrX_+_159560292 2.98 ENSRNOT00000087250
Vgll1
vestigial like family member 1
chr7_+_9279620 2.79 ENSRNOT00000011225
Olr1064
olfactory receptor 1064
chr8_-_114013623 2.78 ENSRNOT00000018175
Atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr3_-_103128243 2.72 ENSRNOT00000046310
Olr779
olfactory receptor 779
chr1_+_168341595 2.60 ENSRNOT00000048411
Olr84
olfactory receptor 84
chr1_-_168611670 2.59 ENSRNOT00000021273
Olr106
olfactory receptor 106
chr7_-_5106708 2.49 ENSRNOT00000046001
Olr892
olfactory receptor 892
chr7_-_15856676 2.48 ENSRNOT00000086553
AABR07055919.1

chr3_-_78409263 2.44 ENSRNOT00000041001
Olr704
olfactory receptor 704
chr5_-_69277783 2.36 ENSRNOT00000046638
Olr847
olfactory receptor 847
chr1_-_149175205 2.29 ENSRNOT00000089091
ENSRNOT00000045611
ENSRNOT00000089015
Vom2r42
vomeronasal 2 receptor, 42
chr1_+_225690756 2.25 ENSRNOT00000027498
Psbpc2
prostatic steroid-binding protein C2
chr3_-_73580594 2.22 ENSRNOT00000012929
Olr488
olfactory receptor 488
chr3_-_78663607 2.04 ENSRNOT00000073134
Olr718
olfactory receptor 718
chr3_-_77792014 1.99 ENSRNOT00000091085
Olr671
olfactory receptor 671
chrX_-_152110010 1.98 ENSRNOT00000044666
LOC100362263
melanoma antigen family A, 5-like
chr1_-_147272006 1.95 ENSRNOT00000086862
AABR07004539.1

chr1_+_60117804 1.90 ENSRNOT00000080437
Vom1r8
vomeronasal 1 receptor 8
chr3_+_75768699 1.79 ENSRNOT00000071912
AABR07052798.1

chr17_-_42817037 1.73 ENSRNOT00000023166
Prl3c1
Prolactin family 3, subfamily c, member 1
chr3_-_78886096 1.72 ENSRNOT00000008864
Olr729
olfactory receptor 729
chr7_+_47928060 1.71 ENSRNOT00000005740
Ccdc59
coiled-coil domain containing 59
chr4_+_87312766 1.69 ENSRNOT00000052126
Vom1r71
vomeronasal 1 receptor 71
chr20_-_11498277 1.69 ENSRNOT00000046763
AABR07044581.1

chr3_+_75834770 1.68 ENSRNOT00000043371
Olr582
olfactory receptor 582
chr1_+_72230038 1.58 ENSRNOT00000058997
Vom1r38
vomeronasal 1 receptor 38
chr4_+_157057601 1.54 ENSRNOT00000040592
Zfp42l
Zinc finger protein 42-like
chr7_-_3707226 1.43 ENSRNOT00000064380
Olr879
olfactory receptor 879
chr3_-_78555530 1.42 ENSRNOT00000089672
Olr711
olfactory receptor 711
chr5_+_108935189 1.31 ENSRNOT00000071169
AABR07049184.1

chr1_+_168403613 1.30 ENSRNOT00000079028
Olr88
olfactory receptor 88
chr1_+_168411463 1.28 ENSRNOT00000072397
Olr89
olfactory receptor 89
chr1_+_230604386 1.25 ENSRNOT00000040608
Olr375
olfactory receptor 375
chr3_+_75437833 1.24 ENSRNOT00000042246
Olr561
olfactory receptor 561
chr3_-_76696107 1.23 ENSRNOT00000044692
Olr629
olfactory receptor 629
chr11_-_43594659 1.22 ENSRNOT00000086976
Olr1555
olfactory receptor 1555
chr11_-_70211701 1.05 ENSRNOT00000076114
Muc13
mucin 13, cell surface associated
chr20_+_734642 0.99 ENSRNOT00000073543
Olr1688
olfactory receptor 1688
chr7_-_47928674 0.96 ENSRNOT00000038144
Mettl25
methyltransferase like 25
chr10_+_61160125 0.95 ENSRNOT00000074715
Olr1519
olfactory receptor 1519
chr18_-_26658892 0.91 ENSRNOT00000038247
Epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr1_-_169770188 0.88 ENSRNOT00000072602
Olr165
olfactory receptor 165
chr3_-_74790822 0.86 ENSRNOT00000045888
LOC100912505
olfactory receptor 8K3-like
chr8_+_25246292 0.86 ENSRNOT00000021625
Npsr1
neuropeptide S receptor 1
chr8_-_50246656 0.78 ENSRNOT00000024240
Sidt2
SID1 transmembrane family, member 2
chr1_-_168015148 0.72 ENSRNOT00000020691
Olr50
olfactory receptor 50
chr1_-_66688422 0.66 ENSRNOT00000082786
Vom1r57
vomeronasal 1 receptor 57
chr1_-_60281386 0.63 ENSRNOT00000092184
Vom1r10
vomeronasal 1 receptor 10
chr8_-_117237229 0.63 ENSRNOT00000071381
Klhdc8b
kelch domain containing 8B
chr1_-_172030164 0.53 ENSRNOT00000026807
Ovch2
ovochymase 2
chr17_+_79749747 0.48 ENSRNOT00000081743
AABR07028665.1

chr2_-_220838905 0.46 ENSRNOT00000078914
AABR07013065.1

chr7_-_143167772 0.37 ENSRNOT00000011374
Krt85
keratin 85
chr2_+_194557986 0.29 ENSRNOT00000070843
LOC100911679
TD and POZ domain-containing protein 2-like
chr14_+_1318157 0.25 ENSRNOT00000061889
Vom2r67
vomeronasal 2 receptor, 67
chr3_+_76768051 0.19 ENSRNOT00000047382
Olr634
olfactory receptor 634
chr1_-_67284864 0.14 ENSRNOT00000082908
LOC691661
similar to zinc finger and SCAN domain containing 4
chr3_-_74906989 0.13 ENSRNOT00000071001
Olr545
olfactory receptor 545
chr1_+_75748916 0.12 ENSRNOT00000083154
ENSRNOT00000089836
Bsph1
binder of sperm protein homolog 1
chr8_+_19888667 0.09 ENSRNOT00000078593
Zfp317
zinc finger protein 317
chr1_-_168310071 0.06 ENSRNOT00000044675
Olr82
olfactory receptor 82
chr3_+_75809445 0.05 ENSRNOT00000049950
Olr581
olfactory receptor 581
chr1_+_169741497 0.02 ENSRNOT00000072865
Olr164
olfactory receptor 164

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
4.5 22.7 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
4.2 50.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
4.1 20.7 GO:1904970 brush border assembly(GO:1904970)
2.5 17.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
2.1 8.4 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
1.7 12.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.6 97.7 GO:0019369 arachidonic acid metabolic process(GO:0019369)
1.4 7.2 GO:0009115 xanthine catabolic process(GO:0009115)
1.2 11.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
1.1 6.6 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
1.1 4.3 GO:0072709 cellular response to sorbitol(GO:0072709)
1.0 7.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.9 2.8 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.9 6.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.8 6.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.8 6.6 GO:0015679 plasma membrane copper ion transport(GO:0015679)
0.5 9.1 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.5 8.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.5 15.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.5 27.6 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.5 3.8 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.5 42.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.4 4.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.3 8.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 4.0 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.2 4.5 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.2 1.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 4.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.9 GO:2000293 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.2 7.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 3.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 4.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 17.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 102.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 9.1 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 7.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 13.1 GO:0070838 divalent metal ion transport(GO:0070838)
0.0 4.1 GO:0007286 spermatid development(GO:0007286)
0.0 14.1 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 20.7 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
2.8 8.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
2.5 22.7 GO:0071821 FANCM-MHF complex(GO:0071821)
1.6 6.6 GO:1990761 growth cone lamellipodium(GO:1990761)
1.5 5.9 GO:0031417 NatC complex(GO:0031417)
1.0 28.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 7.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.4 6.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.4 49.2 GO:0072562 blood microparticle(GO:0072562)
0.2 8.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 4.7 GO:0097449 astrocyte projection(GO:0097449)
0.2 4.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 147.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 4.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 7.0 GO:0005811 lipid particle(GO:0005811)
0.1 34.4 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 7.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 21.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 15.7 GO:0060076 excitatory synapse(GO:0060076)
0.0 3.8 GO:0005901 caveola(GO:0005901)
0.0 185.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 11.6 GO:0005768 endosome(GO:0005768)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 42.6 GO:0003996 acyl-CoA ligase activity(GO:0003996)
5.0 20.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
3.8 22.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.6 147.9 GO:0070330 aromatase activity(GO:0070330)
2.8 8.3 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
2.5 27.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.1 8.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.0 8.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.6 4.7 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.5 17.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
1.4 7.2 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
1.1 6.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.0 3.8 GO:0055100 adiponectin binding(GO:0055100)
0.8 4.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.5 6.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 4.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 7.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 2.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.3 7.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 16.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 6.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 7.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 4.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 4.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 15.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 12.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 102.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 5.4 GO:0043022 ribosome binding(GO:0043022)
0.1 0.9 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 13.1 GO:0072509 divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.1 11.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 6.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.2 GO:0005496 steroid binding(GO:0005496)
0.0 4.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 11.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 9.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 3.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.0 NABA COLLAGENS Genes encoding collagen proteins
0.3 4.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 12.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 8.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 17.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 19.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.6 32.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.5 20.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.5 42.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 16.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 8.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 5.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.2 4.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 3.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 9.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation