Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Junb_Jund

Z-value: 2.55

Motif logo

Transcription factors associated with Junb_Jund

Gene Symbol Gene ID Gene Info
ENSRNOG00000042838 JunB proto-oncogene, AP-1 transcription factor subunit
ENSRNOG00000019568 JunD proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Junbrn6_v1_chr19_-_26094756_26094756-0.363.3e-11Click!
Jundrn6_v1_chr16_-_20486707_204867070.009.6e-01Click!

Activity profile of Junb_Jund motif

Sorted Z-values of Junb_Jund motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_150801289 240.28 ENSRNOT00000035060
microtubule-associated protein 1 light chain 3 alpha
chr15_+_43007908 171.05 ENSRNOT00000084753
ENSRNOT00000091567
ENSRNOT00000087709
stathmin 4
chr8_-_115263484 152.65 ENSRNOT00000039696
ENSRNOT00000081138
IQ motif containing F3
chr6_+_28515025 152.46 ENSRNOT00000088033
ENSRNOT00000005317
ENSRNOT00000081141
DnaJ heat shock protein family (Hsp40) member C27
chr4_+_174181644 147.00 ENSRNOT00000011555
capping actin protein of muscle Z-line alpha subunit 3
chr5_-_146446227 146.93 ENSRNOT00000044868
high-mobility group box 4
chr5_+_59452348 144.25 ENSRNOT00000019887
calicin
chr2_+_164549455 142.83 ENSRNOT00000017151
myeloid leukemia factor 1
chr1_-_169334093 141.94 ENSRNOT00000032587
ubiquilin 3
chr5_-_140024176 137.98 ENSRNOT00000016492
transmembrane and coiled-coil domains 2
chr15_+_28319136 137.03 ENSRNOT00000048723
tubulin polymerization-promoting protein family member 2
chr4_-_169036950 136.44 ENSRNOT00000011295
germ cell associated 1
chr15_+_80040842 133.26 ENSRNOT00000043065
similar to RIKEN cDNA 4921530L21
chr1_-_89194602 130.22 ENSRNOT00000028518
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr4_+_159403501 129.73 ENSRNOT00000086525
A-kinase anchoring protein 3
chr8_-_115274165 129.40 ENSRNOT00000056386
IQ domain-containing protein F5-like
chr7_-_124982566 128.97 ENSRNOT00000075099
sulfotransferase family 4A, member 1
chr7_+_18310624 122.81 ENSRNOT00000075258
actin-like 9
chr11_+_88424414 122.15 ENSRNOT00000022328
sperm associated antigen 6-like
chr6_+_36089433 119.29 ENSRNOT00000090438
ENSRNOT00000005731
5'-nucleotidase, cytosolic IB
chr6_-_86223052 116.51 ENSRNOT00000046828
fibrous sheath CABYR binding protein
chr9_-_85243001 113.30 ENSRNOT00000020219
secretogranin II
chrX_+_142344878 112.13 ENSRNOT00000056621
high mobility group protein B4-like
chr2_+_104290726 110.55 ENSRNOT00000017387
DnaJ heat shock protein family (Hsp40) member C5 beta
chr16_-_82288022 110.23 ENSRNOT00000078609
sperm acrosome associated 7
chr6_-_47848026 109.70 ENSRNOT00000011048
ENSRNOT00000090017
allantoicase
chrX_-_144001727 109.59 ENSRNOT00000078404
similar to RIKEN cDNA 1700001F22
chr2_-_29768750 108.93 ENSRNOT00000023460
microtubule-associated protein 1B
chr9_-_113358526 108.33 ENSRNOT00000065073
thioredoxin domain containing 2
chr9_+_93445002 107.07 ENSRNOT00000025029
similar to hypothetical protein MGC35154
chr15_-_57651041 105.70 ENSRNOT00000072138
spermatid associated
chr1_-_89190128 104.88 ENSRNOT00000067813
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr5_+_73496027 104.63 ENSRNOT00000022395
actin-like 7a
chr9_-_63291350 101.86 ENSRNOT00000058831
heat shock transcription factor, Y linked 2
chr9_+_10172832 101.58 ENSRNOT00000074555
acyl-CoA synthetase bubblegum family member 2
chr18_-_14016713 100.94 ENSRNOT00000041125
nucleolar protein 4
chr1_-_198267093 100.14 ENSRNOT00000047477
similar to RIKEN cDNA 4930451I11
chr1_-_188245628 99.66 ENSRNOT00000022800
transmembrane channel-like 7
chr10_+_89918373 96.06 ENSRNOT00000055192
RGD1565533
chr4_-_157078130 95.28 ENSRNOT00000015570
calsyntenin 3
chr4_-_6449949 94.11 ENSRNOT00000062026
polypeptide N-acetylgalactosaminyltransferase-like 5
chr8_+_115213471 92.45 ENSRNOT00000017570
IQ motif containing F5
chr1_-_81295442 92.20 ENSRNOT00000030900
immunity related GTPase cinema
chrX_-_132424746 92.12 ENSRNOT00000087819
similar to RIKEN cDNA 1700001F22
chr3_+_170475831 91.96 ENSRNOT00000006949
family with sequence similarity 209, member A
chr8_+_115193146 91.14 ENSRNOT00000056391
IQ motif containing F1
chrX_-_139329975 90.67 ENSRNOT00000086405
high mobility group protein B4-like
chrX_-_130794673 90.61 ENSRNOT00000080612
similar to RIKEN cDNA 1700001F22
chr1_+_211582077 89.90 ENSRNOT00000023619
PWWP domain containing 2B
chr15_-_5467047 89.77 ENSRNOT00000042743
Spetex-2F protein
chrX_+_137197396 89.03 ENSRNOT00000082227
similar to RIKEN cDNA 1700001F22
chr2_+_260039651 87.64 ENSRNOT00000073873
ankyrin repeat and SOCS box-containing 17
chrX_+_114929029 86.77 ENSRNOT00000006459
p21 (RAC1) activated kinase 3
chr1_+_97712177 86.50 ENSRNOT00000027745
similar to RIKEN cDNA 4930433I11 gene
chr6_+_122603269 84.54 ENSRNOT00000005297
spermatogenesis associated 7
chr10_+_103992309 82.02 ENSRNOT00000065292
tripartite motif protein 80
chr5_-_75116490 81.79 ENSRNOT00000042788
thioredoxin domain containing 8
chr4_+_56556507 81.26 ENSRNOT00000060353
family with sequence similarity 71, member F2
chr1_-_52495582 80.42 ENSRNOT00000067142
phosphodiesterase 10A
chr17_+_85382116 78.93 ENSRNOT00000002513
sperm associated antigen 6
chr1_+_101603222 78.90 ENSRNOT00000033278
izumo sperm-egg fusion 1
chr18_+_45023932 78.48 ENSRNOT00000039379
family with sequence similarity 170, member A
chr16_-_49574314 77.81 ENSRNOT00000017568
ENSRNOT00000085535
ENSRNOT00000017054
PDZ and LIM domain 3
chr9_-_100253609 77.80 ENSRNOT00000036061
kinesin family member 1A
chr3_+_125428260 76.97 ENSRNOT00000028892
chromogranin B
chr1_-_31055453 76.74 ENSRNOT00000031083
SOGA family member 3
chrX_-_158261717 75.91 ENSRNOT00000086804
similar to RIKEN cDNA 1700001F22
chr15_-_6587367 75.34 ENSRNOT00000038449
zinc finger protein 385D
chr14_-_108284619 74.91 ENSRNOT00000078814
hypothetical protein LOC690352
chr6_-_41870046 74.70 ENSRNOT00000005863
lipin 1
chr9_-_14906410 73.18 ENSRNOT00000061674
hypothetical protein LOC680955
chr14_-_108285008 72.78 ENSRNOT00000087501
hypothetical protein LOC690352
chrX_+_82217143 72.77 ENSRNOT00000086866
cylicin 1
chr5_-_113880911 72.27 ENSRNOT00000029441
equatorin
chr1_+_100501676 71.77 ENSRNOT00000043724
family with sequence similarity 71, member E1
chr8_+_4085829 71.59 ENSRNOT00000031286
actin-like 9b
chr10_+_38104558 71.53 ENSRNOT00000067809
follistatin-like 4
chr3_-_45210474 71.24 ENSRNOT00000091777
coiled-coil domain containing 148
chr12_-_13067341 71.03 ENSRNOT00000029692
family with sequence similarity 220, member A
chr5_-_57896475 70.83 ENSRNOT00000017903
similar to testes development-related NYD-SP22 isoform 1
chr14_-_9456990 69.07 ENSRNOT00000002918
CDP-diacylglycerol synthase 1
chr1_-_72727112 68.41 ENSRNOT00000031172
BR serine/threonine kinase 1
chr3_-_160922341 67.38 ENSRNOT00000029206
TP53 target 5
chr5_-_25584278 66.91 ENSRNOT00000090579
ENSRNOT00000090376
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_+_224938801 66.81 ENSRNOT00000073052
RIKEN cDNA 1700092M07 gene
chr8_-_57255263 65.27 ENSRNOT00000028972
hypothetical protein LOC100125362
chr10_-_56511583 62.58 ENSRNOT00000021402
similar to RIKEN cDNA 2810408A11
chr11_-_32469566 61.97 ENSRNOT00000002718
similar to RIKEN cDNA 4930563D23
chr10_+_49368314 61.66 ENSRNOT00000004392
CMT1A duplicated region transcript 4
chr1_+_72644333 61.48 ENSRNOT00000048976
ENSRNOT00000065051
family with sequence similarity 71, member E2
chr2_-_251970768 61.18 ENSRNOT00000020141
WD repeat domain 63
chr3_+_138974871 60.34 ENSRNOT00000012524
SCP2 sterol-binding domain containing 1
chrX_-_29648359 59.90 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chr6_+_109939345 59.85 ENSRNOT00000013560
intraflagellar transport 43
chr4_-_184096806 58.97 ENSRNOT00000055433
mKIAA1238 protein-like
chr11_+_52828116 58.56 ENSRNOT00000035340
coiled-coil domain containing 54
chr10_+_57239993 57.59 ENSRNOT00000067919
hypothetical protein LOC687707
chr2_+_157453428 57.44 ENSRNOT00000051494
leucine, glutamate and lysine rich 1
chr16_+_20691978 57.26 ENSRNOT00000038139
ENSRNOT00000082319
transmembrane protein 59-like
chr13_+_104284660 57.18 ENSRNOT00000005400
dual specificity phosphatase 10
chr8_-_87282156 56.37 ENSRNOT00000087874
filamin A interacting protein 1
chr4_-_85915099 55.98 ENSRNOT00000016182
neuronal differentiation 6
chr7_+_40318490 55.82 ENSRNOT00000081374
similar to hypothetical protein FLJ35821
chr15_+_23777856 55.67 ENSRNOT00000060847
sterile alpha motif domain containing 4A
chr6_-_126622532 54.95 ENSRNOT00000038816
modulator of apoptosis 1
chr10_-_14056169 54.66 ENSRNOT00000017833
synaptogyrin 3
chr10_-_91699424 54.60 ENSRNOT00000004650
lysozyme-like 6
chr6_+_147876237 54.39 ENSRNOT00000056649
transmembrane protein 196
chr2_+_220298245 53.68 ENSRNOT00000022625
phospholipid phosphatase related 4
chr13_-_104284068 53.08 ENSRNOT00000005407
uncharacterized LOC100912365
chr17_-_9695292 52.79 ENSRNOT00000036162
proline rich 7 (synaptic)
chr1_-_220467159 52.46 ENSRNOT00000075365
transmembrane protein 151A
chr10_+_82775691 52.25 ENSRNOT00000030737
histone linker H1 domain, spermatid-specific 1
chr6_+_126434226 52.04 ENSRNOT00000090857
chromogranin A
chr8_+_64364741 51.57 ENSRNOT00000082840
CUGBP, Elav-like family member 6
chr16_+_83161880 51.36 ENSRNOT00000080793
RIKEN cDNA 1700016D06 gene
chr12_+_13390859 51.01 ENSRNOT00000080489
speedy/RINGO cell cycle regulator family member E4
chrX_+_13992064 50.80 ENSRNOT00000036543
rCG42854-like
chr9_-_16095007 50.58 ENSRNOT00000073333

chr1_+_111849998 49.81 ENSRNOT00000033811
leucine zipper protein 2
chr10_-_89918427 49.34 ENSRNOT00000084217
dual specificity phosphatase 3
chr15_+_52265557 48.89 ENSRNOT00000015969
nudix hydrolase 18
chr4_-_156945126 48.50 ENSRNOT00000064853
LOC362433
chr1_-_198382614 48.48 ENSRNOT00000055016
aspartate beta-hydroxylase domain containing 1
chr1_+_102849889 47.80 ENSRNOT00000066791
general transcription factor IIH subunit 1
chr9_+_10535340 47.68 ENSRNOT00000075408
zinc and ring finger 4
chr4_-_88565292 47.15 ENSRNOT00000008948
LanC like 2
chr19_-_11669578 47.07 ENSRNOT00000026373
G protein subunit alpha o1
chr5_-_144779212 47.04 ENSRNOT00000016230
neurochondrin
chr4_-_183697531 46.76 ENSRNOT00000055441
antagonist of mitotic exit network 1 homolog
chr10_+_49472460 46.49 ENSRNOT00000038276
tektin 3
chr3_-_112371664 46.03 ENSRNOT00000079606
ENSRNOT00000012636
leucine-rich repeat-containing protein 57-like
chr7_-_140951071 45.94 ENSRNOT00000082521
family with sequence similarity 186, member B
chr10_-_17721233 45.73 ENSRNOT00000031337
small integral membrane protein 23
chr18_+_47613854 45.50 ENSRNOT00000025270
zinc finger protein 474
chr3_+_121128368 44.26 ENSRNOT00000055882
similar to hypothetical protein 4933411G11
chr9_-_93735636 43.98 ENSRNOT00000025582
natriuretic peptide C
chr2_-_104461863 43.65 ENSRNOT00000016953
corticotropin releasing hormone
chr8_-_61519507 43.60 ENSRNOT00000038347
outer dense fiber of sperm tails 3-like 1
chr11_+_80358211 43.20 ENSRNOT00000002519
somatostatin
chr20_-_37700937 43.08 ENSRNOT00000001051
TBC1 domain family, member 32
chr17_+_1679627 42.92 ENSRNOT00000025801
hyaluronan binding protein 4
chr3_+_137618898 42.84 ENSRNOT00000007249
proprotein convertase subtilisin/kexin type 2
chrX_+_151103576 42.41 ENSRNOT00000015401
SLIT and NTRK-like family, member 2
chr20_+_29655226 42.25 ENSRNOT00000089059
SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2
chr11_-_69355854 42.15 ENSRNOT00000002975
rhophilin associated tail protein 1
chr5_-_39611053 42.14 ENSRNOT00000046595
four and a half LIM domains 5
chr1_-_215033460 42.14 ENSRNOT00000044565
dual specificity phosphatase 8
chr8_+_58431407 41.84 ENSRNOT00000011974
sarcolipin
chr20_+_13498926 41.40 ENSRNOT00000070992
ENSRNOT00000045375
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr8_-_17524839 41.26 ENSRNOT00000081679
N-acetylated alpha-linked acidic dipeptidase 2
chr13_+_49003803 41.03 ENSRNOT00000080556
LEM domain containing 1
chr15_-_5417570 40.87 ENSRNOT00000061525
Spetex-2F protein
chr18_-_24057917 40.82 ENSRNOT00000023874
Ras-like without CAAX 2
chr10_+_75620470 40.35 ENSRNOT00000013882
coiled-coil domain containing 182
chr1_+_97777685 38.57 ENSRNOT00000030895
similar to F49E2.5d
chr2_-_30748325 38.40 ENSRNOT00000084294
ENSRNOT00000083089
mitochondrial ribosomal protein S36
chr9_-_19613360 38.29 ENSRNOT00000029593
regulator of calcineurin 2
chr10_-_91186054 38.27 ENSRNOT00000004140
phospholipase C, delta 3
chr8_+_48422036 37.80 ENSRNOT00000036051
ubiquitin specific peptidase 2
chr8_+_60117729 37.61 ENSRNOT00000021074
ISL LIM homeobox 2
chr9_-_28732919 37.55 ENSRNOT00000083915
regulating synaptic membrane exocytosis 1
chr5_-_65073012 37.18 ENSRNOT00000007957
glutamate ionotropic receptor NMDA type subunit 3A
chr9_+_102862890 37.05 ENSRNOT00000050494
ENSRNOT00000080129
family with sequence similarity 174, member A
chr13_+_88644520 37.02 ENSRNOT00000003979
spermatogenesis associated 46
chr10_+_94192556 36.52 ENSRNOT00000074007
ENSRNOT00000093039
angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
chr9_+_82674202 36.49 ENSRNOT00000027208
transmembrane protein 198
chr17_+_27452638 36.38 ENSRNOT00000038349
cancer antigen 1
chr1_+_218945508 36.02 ENSRNOT00000034240
similar to RIKEN cDNA 1810055G02
chr4_+_70977556 35.09 ENSRNOT00000031984
hypothetical protein LOC680112
chr7_-_72328128 34.70 ENSRNOT00000008227
TSPY-like 5
chr5_+_103479767 34.66 ENSRNOT00000008999
SH3 domain-containing GRB2-like 2
chr10_+_88356615 34.64 ENSRNOT00000022687
kelch-like family member 10
chr11_-_87240833 34.44 ENSRNOT00000052200
testis-specific serine kinase 1B
chr20_-_12835044 34.43 ENSRNOT00000074268
speriolin-like protein
chr2_+_233602732 34.28 ENSRNOT00000044232
paired-like homeodomain 2
chr1_+_211205903 34.16 ENSRNOT00000023139
protein phosphatase 2, regulatory subunit B, delta
chr6_+_98284170 33.95 ENSRNOT00000031979
ras homolog family member J
chr1_-_225035687 33.91 ENSRNOT00000026539
G protein subunit gamma 3
chr10_-_36716601 33.83 ENSRNOT00000038838
similar to hypothetical protein 4930503F14
chr9_+_82053581 33.81 ENSRNOT00000086375
wingless-type MMTV integration site family, member 10A
chr1_+_201913148 33.64 ENSRNOT00000036128
family with sequence similarity 24, member A
chr14_+_8080275 33.31 ENSRNOT00000065965
ENSRNOT00000092542
mitogen activated protein kinase 10
chr9_+_99998275 32.99 ENSRNOT00000074395
glypican 1
chr20_-_45815940 32.52 ENSRNOT00000073276
G protein-coupled receptor 6
chr1_-_24604400 32.43 ENSRNOT00000081175
RIKEN cDNA 1700020N01 gene
chr7_+_123168811 32.43 ENSRNOT00000007091
cold shock domain containing C2
chr6_-_42473738 32.32 ENSRNOT00000033327
potassium voltage-gated channel modifier subfamily F member 1
chr3_-_3266260 31.88 ENSRNOT00000034538
glycosyltransferase 6 domain containing 1
chrX_-_82986051 31.84 ENSRNOT00000077587
highly divergent homeobox
chr15_-_47442664 31.47 ENSRNOT00000072994
protease, serine, 55
chr3_+_150910398 31.42 ENSRNOT00000055310
tumor protein p53 inducible nuclear protein 2
chr7_-_44121130 31.29 ENSRNOT00000005706
neurotensin
chr6_-_110681408 31.25 ENSRNOT00000078265
angel homolog 1
chr10_+_70520206 31.23 ENSRNOT00000088198
ENSRNOT00000090446
ENSRNOT00000085799
adaptor-related protein complex 2, beta 1 subunit
chr17_+_7675531 31.21 ENSRNOT00000061187
sparc/osteonectin, cwcv and kazal like domains proteoglycan 1
chr7_+_72924799 30.96 ENSRNOT00000008969
lysosomal protein transmembrane 4 beta
chr10_+_89376530 30.92 ENSRNOT00000028089
Rho family GTPase 2
chr10_-_82252720 30.72 ENSRNOT00000066132
ENSRNOT00000075795
Mycbp associated protein
chr10_-_27179900 30.62 ENSRNOT00000082445
gamma-aminobutyric acid type A receptor gamma 2 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of Junb_Jund

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
36.6 109.7 GO:0043605 cellular amide catabolic process(GO:0043605)
22.8 91.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
20.4 265.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
18.8 37.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
17.3 52.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
16.4 49.3 GO:0060577 pulmonary vein morphogenesis(GO:0060577)
16.3 48.9 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
16.0 64.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
16.0 240.3 GO:0010040 response to iron(II) ion(GO:0010040)
15.7 47.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
15.6 77.8 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
15.5 46.5 GO:0080154 regulation of fertilization(GO:0080154)
14.4 129.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
14.3 57.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
12.5 37.6 GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
11.1 111.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
11.0 33.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
11.0 44.0 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
11.0 55.0 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
10.8 183.6 GO:0006662 glycerol ether metabolic process(GO:0006662)
10.7 74.7 GO:0006642 triglyceride mobilization(GO:0006642)
10.6 84.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
9.6 38.6 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
9.6 105.9 GO:0046085 adenosine metabolic process(GO:0046085)
9.6 77.0 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
9.5 95.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
9.4 18.8 GO:0051012 microtubule sliding(GO:0051012)
9.1 18.2 GO:0061741 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
8.9 26.7 GO:0021629 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
8.7 61.2 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
8.7 26.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
8.6 42.8 GO:0030070 insulin processing(GO:0030070)
8.4 108.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
8.1 122.1 GO:0007288 sperm axoneme assembly(GO:0007288)
8.1 105.6 GO:0046069 cGMP catabolic process(GO:0046069)
8.0 23.9 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
7.9 71.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
7.8 31.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
7.6 113.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
7.0 21.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
6.8 40.8 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
6.7 33.4 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
6.6 26.5 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
6.6 26.3 GO:0061084 negative regulation of protein refolding(GO:0061084)
6.3 50.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
6.3 31.3 GO:0097332 response to antipsychotic drug(GO:0097332)
6.0 59.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
5.9 147.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
5.8 34.6 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
5.4 16.1 GO:0045054 constitutive secretory pathway(GO:0045054)
5.3 42.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
5.3 5.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
5.2 36.3 GO:0097278 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659)
5.1 45.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
5.1 25.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
5.0 55.5 GO:0007258 JUN phosphorylation(GO:0007258)
5.0 34.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
4.5 9.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
4.5 13.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
4.5 17.9 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
4.4 13.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
4.4 17.4 GO:0015888 thiamine transport(GO:0015888)
4.3 17.4 GO:0007341 penetration of zona pellucida(GO:0007341)
4.3 21.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
4.1 12.2 GO:0030186 melatonin metabolic process(GO:0030186)
4.0 12.1 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
3.8 19.1 GO:0035063 nuclear speck organization(GO:0035063)
3.8 34.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
3.8 7.6 GO:0019086 late viral transcription(GO:0019086)
3.7 14.8 GO:0052314 phytoalexin metabolic process(GO:0052314)
3.7 88.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
3.6 277.3 GO:0030317 sperm motility(GO:0030317)
3.6 43.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
3.6 25.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
3.6 21.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
3.5 17.6 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
3.5 145.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
3.4 10.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
3.3 29.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
3.2 38.2 GO:0007614 short-term memory(GO:0007614)
3.2 41.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
3.2 25.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
3.1 56.4 GO:0060134 prepulse inhibition(GO:0060134)
3.1 25.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
3.1 24.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
3.0 63.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
3.0 74.1 GO:0071625 vocalization behavior(GO:0071625)
2.9 14.7 GO:0070173 regulation of enamel mineralization(GO:0070173)
2.9 31.9 GO:0030259 lipid glycosylation(GO:0030259)
2.9 11.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
2.9 8.6 GO:0032472 Golgi calcium ion transport(GO:0032472)
2.8 11.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.8 59.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
2.8 30.6 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
2.7 10.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
2.7 13.3 GO:0061709 reticulophagy(GO:0061709)
2.6 36.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
2.5 17.7 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
2.5 10.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
2.5 19.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
2.4 9.7 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
2.4 37.8 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
2.4 7.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
2.3 84.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
2.3 33.8 GO:0048733 sebaceous gland development(GO:0048733)
2.2 22.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
2.2 55.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
2.2 17.8 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
2.2 19.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
2.2 13.0 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.2 8.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
2.2 13.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
2.0 24.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
2.0 13.7 GO:0010587 miRNA catabolic process(GO:0010587)
1.9 9.7 GO:0006311 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
1.9 27.1 GO:0042026 protein refolding(GO:0042026)
1.9 11.6 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
1.9 19.0 GO:0032782 bile acid secretion(GO:0032782)
1.9 5.6 GO:0036451 cap mRNA methylation(GO:0036451)
1.9 24.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
1.8 9.0 GO:0035617 stress granule disassembly(GO:0035617)
1.8 5.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.7 42.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.7 139.1 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
1.7 5.2 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
1.7 15.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.7 8.6 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
1.7 6.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
1.7 43.2 GO:0010447 response to acidic pH(GO:0010447)
1.6 52.3 GO:0030261 chromosome condensation(GO:0030261)
1.6 30.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.6 17.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
1.6 6.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
1.6 19.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.6 40.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.5 39.9 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
1.5 6.1 GO:0035494 SNARE complex disassembly(GO:0035494)
1.5 6.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
1.5 4.5 GO:1990792 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
1.5 5.9 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.4 10.1 GO:0042256 mature ribosome assembly(GO:0042256)
1.4 18.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.4 8.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.4 17.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.3 26.8 GO:0045116 protein neddylation(GO:0045116)
1.3 41.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.3 12.9 GO:0006000 fructose metabolic process(GO:0006000)
1.3 9.0 GO:0055064 chloride ion homeostasis(GO:0055064)
1.3 35.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.3 3.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.2 14.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.2 7.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
1.2 19.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
1.2 176.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
1.2 113.1 GO:0007338 single fertilization(GO:0007338)
1.2 1.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.2 147.4 GO:0007286 spermatid development(GO:0007286)
1.2 19.7 GO:0006622 protein targeting to lysosome(GO:0006622)
1.1 13.6 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
1.1 26.9 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
1.1 28.6 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
1.1 9.9 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
1.1 54.3 GO:0021762 substantia nigra development(GO:0021762)
1.1 24.3 GO:0048745 smooth muscle tissue development(GO:0048745)
1.0 8.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
1.0 3.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.0 22.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
1.0 10.8 GO:0060973 cell migration involved in heart development(GO:0060973)
1.0 14.6 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
1.0 5.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
1.0 101.6 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
1.0 60.3 GO:0015914 phospholipid transport(GO:0015914)
0.9 14.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.9 10.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.9 11.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.9 34.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.8 47.1 GO:0051298 centrosome duplication(GO:0051298)
0.8 9.8 GO:0070365 hepatocyte differentiation(GO:0070365)
0.8 26.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.7 3.7 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.7 10.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.7 7.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.7 15.0 GO:0044458 motile cilium assembly(GO:0044458)
0.7 27.6 GO:0009994 oocyte differentiation(GO:0009994)
0.7 4.9 GO:0015871 choline transport(GO:0015871)
0.7 42.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.7 8.0 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.6 15.2 GO:0006611 protein export from nucleus(GO:0006611)
0.6 3.0 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.6 9.4 GO:0021542 dentate gyrus development(GO:0021542)
0.6 4.6 GO:0030953 astral microtubule organization(GO:0030953)
0.6 1.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.6 1.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.5 3.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.5 2.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.5 13.1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.5 9.0 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.5 30.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.5 29.1 GO:0000045 autophagosome assembly(GO:0000045)
0.5 2.4 GO:0015819 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.5 3.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.5 8.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.4 36.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.4 1.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.4 3.9 GO:1904874 regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.4 51.5 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.4 16.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.4 12.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.4 7.2 GO:0002076 osteoblast development(GO:0002076)
0.4 3.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.4 41.9 GO:0048813 dendrite morphogenesis(GO:0048813)
0.4 6.3 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.4 11.0 GO:0009303 rRNA transcription(GO:0009303)
0.4 6.0 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.4 2.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.4 31.0 GO:0008585 female gonad development(GO:0008585)
0.4 99.5 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.4 2.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 5.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 10.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.4 9.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.3 0.6 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.3 2.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3 2.6 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.3 18.8 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.3 1.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.2 2.7 GO:0007635 chemosensory behavior(GO:0007635)
0.2 1.9 GO:0034063 stress granule assembly(GO:0034063)
0.2 35.1 GO:0010506 regulation of autophagy(GO:0010506)
0.2 32.0 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.2 14.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 2.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 4.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 1.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 32.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2 0.8 GO:0006105 succinate metabolic process(GO:0006105)
0.2 1.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 6.0 GO:0030239 myofibril assembly(GO:0030239)
0.1 11.7 GO:0050821 protein stabilization(GO:0050821)
0.1 1.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.7 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 9.3 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.4 GO:0090399 replicative senescence(GO:0090399)
0.1 0.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 1.7 GO:0034508 centromere complex assembly(GO:0034508)
0.1 2.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 3.2 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 4.3 GO:0006457 protein folding(GO:0006457)
0.0 0.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 1.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 3.3 GO:0006364 rRNA processing(GO:0006364)
0.0 2.0 GO:0035304 regulation of protein dephosphorylation(GO:0035304)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
31.1 529.3 GO:0035686 sperm fibrous sheath(GO:0035686)
24.4 122.1 GO:1990716 axonemal central apparatus(GO:1990716)
18.1 72.3 GO:0002079 inner acrosomal membrane(GO:0002079)
18.0 90.2 GO:0043159 acrosomal matrix(GO:0043159)
16.0 240.3 GO:0044754 autolysosome(GO:0044754)
14.7 147.0 GO:0008290 F-actin capping protein complex(GO:0008290)
10.5 42.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
9.6 38.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
9.4 66.1 GO:0097524 sperm plasma membrane(GO:0097524)
8.6 59.9 GO:0030991 intraciliary transport particle A(GO:0030991)
8.3 41.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
8.0 160.2 GO:0043196 varicosity(GO:0043196)
7.1 70.8 GO:0002177 manchette(GO:0002177)
6.9 103.2 GO:0031045 dense core granule(GO:0031045)
6.5 156.9 GO:0001673 male germ cell nucleus(GO:0001673)
6.5 52.0 GO:0042583 chromaffin granule(GO:0042583)
6.5 19.4 GO:0090534 calcium ion-transporting ATPase complex(GO:0090534)
6.0 108.3 GO:0001520 outer dense fiber(GO:0001520)
5.9 17.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
5.7 22.9 GO:0036128 CatSper complex(GO:0036128)
5.5 125.4 GO:0002080 acrosomal membrane(GO:0002080)
5.3 47.8 GO:0000439 core TFIIH complex(GO:0000439)
4.7 37.6 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
4.3 29.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
4.1 423.6 GO:0001669 acrosomal vesicle(GO:0001669)
4.0 12.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
4.0 24.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
3.9 55.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
3.6 28.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
3.3 13.2 GO:0097196 Shu complex(GO:0097196)
2.6 18.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
2.5 19.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
2.4 35.4 GO:0035253 ciliary rootlet(GO:0035253)
2.2 37.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
2.2 6.5 GO:0035577 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
2.1 4.3 GO:0000322 storage vacuole(GO:0000322)
2.1 44.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
2.1 59.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
2.0 81.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
2.0 147.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.9 5.8 GO:0046691 intracellular canaliculus(GO:0046691)
1.9 70.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
1.8 49.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.8 180.4 GO:0031514 motile cilium(GO:0031514)
1.8 5.4 GO:0044308 axonal spine(GO:0044308)
1.8 21.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.7 12.2 GO:0005869 dynactin complex(GO:0005869)
1.6 14.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.6 9.8 GO:0000125 PCAF complex(GO:0000125)
1.5 6.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.5 9.1 GO:0031080 nuclear pore outer ring(GO:0031080)
1.5 16.6 GO:0032839 dendrite cytoplasm(GO:0032839)
1.5 14.8 GO:0042788 polysomal ribosome(GO:0042788)
1.4 26.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.3 25.4 GO:0032279 asymmetric synapse(GO:0032279)
1.3 30.6 GO:1902711 GABA-A receptor complex(GO:1902711)
1.3 31.2 GO:0033268 node of Ranvier(GO:0033268)
1.3 6.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.2 33.4 GO:0034451 centriolar satellite(GO:0034451)
1.2 7.2 GO:0098871 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
1.1 28.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
1.1 30.2 GO:0031430 M band(GO:0031430)
1.1 4.5 GO:0070545 PeBoW complex(GO:0070545)
1.1 11.6 GO:0030127 COPII vesicle coat(GO:0030127)
1.1 182.4 GO:0030426 growth cone(GO:0030426)
1.0 231.5 GO:0030141 secretory granule(GO:0030141)
1.0 131.5 GO:0043204 perikaryon(GO:0043204)
1.0 33.7 GO:0001772 immunological synapse(GO:0001772)
1.0 12.8 GO:0046581 intercellular canaliculus(GO:0046581)
1.0 88.4 GO:0030018 Z disc(GO:0030018)
1.0 8.7 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.9 46.5 GO:0031594 neuromuscular junction(GO:0031594)
0.9 185.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.8 6.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.8 9.0 GO:0032426 stereocilium tip(GO:0032426)
0.8 9.7 GO:0000801 central element(GO:0000801)
0.8 23.3 GO:0060170 ciliary membrane(GO:0060170)
0.7 26.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.7 10.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 12.6 GO:0030904 retromer complex(GO:0030904)
0.6 5.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.6 24.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.6 6.7 GO:0030008 TRAPP complex(GO:0030008)
0.6 10.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.6 115.4 GO:0030133 transport vesicle(GO:0030133)
0.5 15.2 GO:0046930 pore complex(GO:0046930)
0.5 20.1 GO:0005801 cis-Golgi network(GO:0005801)
0.5 9.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.5 32.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.5 27.6 GO:0005776 autophagosome(GO:0005776)
0.5 57.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.5 11.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 53.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.4 103.8 GO:0005768 endosome(GO:0005768)
0.4 1.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.4 4.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 6.4 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) AMPA glutamate receptor complex(GO:0032281) neurotransmitter receptor complex(GO:0098878)
0.4 23.2 GO:0016234 inclusion body(GO:0016234)
0.4 8.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.3 40.6 GO:0031965 nuclear membrane(GO:0031965)
0.3 8.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.3 89.9 GO:0030424 axon(GO:0030424)
0.3 15.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 4.3 GO:0048786 presynaptic active zone(GO:0048786)
0.3 3.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 0.8 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.3 13.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 69.3 GO:0045202 synapse(GO:0045202)
0.2 2.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 0.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 11.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 23.7 GO:0005882 intermediate filament(GO:0005882)
0.2 3.9 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.2 2.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 1.9 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 7.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 6.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 5.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.4 GO:1990879 CST complex(GO:1990879)
0.1 5.1 GO:0005643 nuclear pore(GO:0005643)
0.1 9.0 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 24.0 GO:0044297 cell body(GO:0044297)
0.1 3.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 5.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 1.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 35.1 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 2.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 5.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 8.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 125.2 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.6 GO:0045177 apical part of cell(GO:0045177)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
58.8 235.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
24.0 240.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
23.8 190.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
23.7 71.0 GO:0097677 STAT family protein binding(GO:0097677)
23.0 69.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
22.3 66.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
19.7 59.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
16.4 98.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
16.3 48.9 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
14.3 71.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
12.6 50.4 GO:0030614 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
11.5 80.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
10.2 30.5 GO:0052743 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) inositol tetrakisphosphate phosphatase activity(GO:0052743)
9.6 162.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
9.1 36.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
8.8 78.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
8.5 101.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
8.4 108.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
7.3 123.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
7.2 86.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
6.6 33.0 GO:0070052 collagen V binding(GO:0070052)
6.3 25.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
6.2 43.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
5.8 17.4 GO:0004040 amidase activity(GO:0004040)
5.7 22.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
5.6 22.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
5.5 55.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
5.4 70.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
5.4 26.8 GO:0051373 FATZ binding(GO:0051373)
5.1 25.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
5.0 89.3 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
4.6 27.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
4.4 17.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
4.2 54.1 GO:0050321 tau-protein kinase activity(GO:0050321)
4.1 41.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
4.1 69.6 GO:0097602 cullin family protein binding(GO:0097602)
4.0 113.3 GO:0042056 chemoattractant activity(GO:0042056)
3.9 73.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
3.8 11.5 GO:0017098 UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
3.7 37.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
3.6 17.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
3.3 33.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
3.2 9.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
3.1 40.8 GO:0030215 semaphorin receptor binding(GO:0030215)
3.0 6.0 GO:0005163 nerve growth factor receptor binding(GO:0005163)
3.0 149.9 GO:0070063 RNA polymerase binding(GO:0070063)
3.0 21.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
3.0 76.9 GO:0043014 alpha-tubulin binding(GO:0043014)
2.9 5.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
2.8 73.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
2.8 19.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.8 49.8 GO:0017160 Ral GTPase binding(GO:0017160)
2.7 24.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
2.7 56.6 GO:0002162 dystroglycan binding(GO:0002162)
2.7 47.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
2.7 8.0 GO:0008142 oxysterol binding(GO:0008142)
2.6 31.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
2.6 31.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
2.5 10.0 GO:0016492 nerve growth factor receptor activity(GO:0010465) G-protein coupled neurotensin receptor activity(GO:0016492)
2.4 31.7 GO:0003796 lysozyme activity(GO:0003796)
2.4 72.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
2.4 23.9 GO:0034190 apolipoprotein receptor binding(GO:0034190)
2.3 52.3 GO:0015248 sterol transporter activity(GO:0015248)
2.3 419.6 GO:0005516 calmodulin binding(GO:0005516)
2.2 11.0 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
2.2 30.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
2.2 13.0 GO:0004994 somatostatin receptor activity(GO:0004994)
2.1 14.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.1 129.0 GO:0008146 sulfotransferase activity(GO:0008146)
2.0 6.1 GO:0015254 glycerol channel activity(GO:0015254)
2.0 6.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
2.0 38.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
1.9 52.4 GO:0030371 translation repressor activity(GO:0030371)
1.9 25.0 GO:0042043 neurexin family protein binding(GO:0042043)
1.9 19.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.9 15.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.9 5.6 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
1.8 16.6 GO:0030957 Tat protein binding(GO:0030957)
1.8 17.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.8 5.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.7 42.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.7 95.4 GO:0051018 protein kinase A binding(GO:0051018)
1.5 24.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.5 25.3 GO:0005523 tropomyosin binding(GO:0005523)
1.5 37.8 GO:0030332 cyclin binding(GO:0030332)
1.4 13.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.4 8.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.4 17.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
1.3 18.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
1.2 17.2 GO:0051378 serotonin binding(GO:0051378)
1.2 6.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.2 10.8 GO:0045499 chemorepellent activity(GO:0045499)
1.2 12.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.1 14.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
1.1 4.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.1 18.6 GO:0008171 O-methyltransferase activity(GO:0008171)
1.1 52.9 GO:0042805 actinin binding(GO:0042805)
1.0 3.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
1.0 319.9 GO:0015631 tubulin binding(GO:0015631)
1.0 5.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.0 3.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.0 5.0 GO:0030911 TPR domain binding(GO:0030911)
1.0 50.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
1.0 6.8 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
1.0 28.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
1.0 18.1 GO:0008199 ferric iron binding(GO:0008199)
0.9 35.8 GO:0005109 frizzled binding(GO:0005109)
0.9 10.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.9 89.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.9 2.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.9 5.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.9 10.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.9 8.6 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.9 63.4 GO:0002039 p53 binding(GO:0002039)
0.8 13.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.8 23.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 22.5 GO:0050681 androgen receptor binding(GO:0050681)
0.7 81.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.7 60.9 GO:0051082 unfolded protein binding(GO:0051082)
0.7 25.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.7 9.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.7 22.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.7 12.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.7 33.7 GO:0030276 clathrin binding(GO:0030276)
0.6 7.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.6 41.3 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.6 5.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.6 19.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.5 14.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 8.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.4 111.1 GO:0003924 GTPase activity(GO:0003924)
0.4 12.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.4 14.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 1.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.4 2.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 11.5 GO:0019894 kinesin binding(GO:0019894)
0.4 11.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.4 32.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.4 10.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 1.0 GO:2001070 starch binding(GO:2001070)
0.3 9.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.3 71.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 16.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 6.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 32.0 GO:0005179 hormone activity(GO:0005179)
0.3 71.6 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.3 36.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 23.4 GO:0008083 growth factor activity(GO:0008083)
0.2 8.6 GO:0017046 peptide hormone binding(GO:0017046)
0.2 79.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 2.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 1.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 3.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 2.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 4.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 3.8 GO:0043022 ribosome binding(GO:0043022)
0.1 9.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 3.8 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 2.5 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 32.3 GO:0008289 lipid binding(GO:0008289)
0.1 4.4 GO:0043130 ubiquitin binding(GO:0043130)
0.1 4.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 38.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
3.0 44.5 PID S1P S1P4 PATHWAY S1P4 pathway
2.6 109.5 PID REELIN PATHWAY Reelin signaling pathway
2.5 68.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
2.4 25.9 ST JAK STAT PATHWAY Jak-STAT Pathway
2.2 85.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
1.9 67.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
1.4 21.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.9 8.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.9 38.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.8 38.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.8 21.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.7 6.5 PID IL5 PATHWAY IL5-mediated signaling events
0.6 4.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.6 8.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.6 22.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.5 14.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.5 10.2 PID ARF 3PATHWAY Arf1 pathway
0.5 8.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.4 8.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.3 14.9 NABA COLLAGENS Genes encoding collagen proteins
0.3 16.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.3 2.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 5.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 3.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 11.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.0 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
11.9 119.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
9.9 129.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
7.0 274.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
6.3 56.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
4.5 66.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
4.2 105.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
3.9 65.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
3.4 47.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
3.2 13.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
3.0 17.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
2.8 41.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
2.7 8.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
2.7 81.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
2.4 55.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
2.3 37.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
2.2 47.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
1.9 53.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
1.8 39.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.8 30.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.8 33.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.7 50.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.7 18.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.6 28.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
1.6 35.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.5 20.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.4 72.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
1.4 26.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.3 13.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.3 18.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.2 13.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
1.2 24.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
1.1 17.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.0 84.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
1.0 24.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.9 16.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.8 24.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.8 30.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.7 38.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.7 21.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 56.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.6 11.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.6 4.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.6 8.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.6 9.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.6 18.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5 6.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 6.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 24.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 6.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.3 3.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 14.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 6.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 8.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 2.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 8.6 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.2 10.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 2.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 3.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 7.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 11.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation