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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Klf13

Z-value: 0.74

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Transcription factors associated with Klf13

Gene Symbol Gene ID Gene Info
Klf13
ENSRNOG00000015822 Kruppel-like factor 13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf13rn6_v1_chr1_-_124803363_124803363-0.044.5e-01Click!

Activity profile of Klf13 motif

Sorted Z-values of Klf13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_5049496 18.46 ENSRNOT00000088251
ENSRNOT00000001118
Ddah2
dimethylarginine dimethylaminohydrolase 2
chr20_-_5155293 18.38 ENSRNOT00000092322
Prrc2a
proline-rich coiled-coil 2A
chr6_-_39363367 17.60 ENSRNOT00000088687
ENSRNOT00000065531
Fam84a
family with sequence similarity 84, member A
chr5_+_64476317 12.91 ENSRNOT00000017217
LOC108348074
collagen alpha-1(XV) chain-like
chr5_+_29538380 12.49 ENSRNOT00000010845
Calb1
calbindin 1
chr9_+_113699170 11.73 ENSRNOT00000017915
Twsg1
twisted gastrulation BMP signaling modulator 1
chr19_+_26106838 11.41 ENSRNOT00000035987
Hook2
hook microtubule-tethering protein 2
chr4_-_117153907 11.09 ENSRNOT00000091374
Rab11fip5
RAB11 family interacting protein 5
chr19_+_10563423 9.95 ENSRNOT00000021037
Dok4
docking protein 4
chr5_+_138470069 9.93 ENSRNOT00000076343
ENSRNOT00000064073
Zmynd12
zinc finger, MYND-type containing 12
chr16_-_19894591 9.37 ENSRNOT00000085940
Ano8
anoctamin 8
chr5_-_159583049 9.28 ENSRNOT00000055839
Crocc
ciliary rootlet coiled-coil, rootletin
chr12_-_44279002 9.17 ENSRNOT00000064900
Fbxo21
F-box protein 21
chr5_+_159428515 8.49 ENSRNOT00000010183
Padi2
peptidyl arginine deiminase 2
chr12_+_22026075 8.37 ENSRNOT00000029041
LOC100910838
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr1_-_101500850 8.31 ENSRNOT00000028390
Nucb1
nucleobindin 1
chr5_+_154489590 8.23 ENSRNOT00000035788
Id3
inhibitor of DNA binding 3, HLH protein
chr12_-_24046814 8.20 ENSRNOT00000001961
Por
cytochrome p450 oxidoreductase
chr7_+_12619774 7.71 ENSRNOT00000015257
Med16
mediator complex subunit 16
chr3_+_2480232 7.47 ENSRNOT00000014489
Tprn
taperin
chr9_+_66335492 7.22 ENSRNOT00000037555
RGD1562029
similar to KIAA2012 protein
chr1_+_80092403 7.10 ENSRNOT00000078336
Eml2
echinoderm microtubule associated protein like 2
chr1_+_80141630 6.82 ENSRNOT00000029552
Opa3
optic atrophy 3
chr13_+_41883137 6.45 ENSRNOT00000004581
Slc35f5
solute carrier family 35, member F5
chr1_+_166739532 5.90 ENSRNOT00000079846
ENSRNOT00000026665
Clpb
ClpB homolog, mitochondrial AAA ATPase chaperonin
chr4_+_115473811 5.81 ENSRNOT00000042875
Nagk
N-acetylglucosamine kinase
chr10_-_64550145 5.63 ENSRNOT00000050232
Nxn
nucleoredoxin
chr1_+_266530477 5.58 ENSRNOT00000054699
Cnnm2
cyclin and CBS domain divalent metal cation transport mediator 2
chr19_+_57047830 5.25 ENSRNOT00000080860
Galnt2
polypeptide N-acetylgalactosaminyltransferase 2
chr8_+_12823155 5.17 ENSRNOT00000011008
Sesn3
sestrin 3
chr5_-_58484900 5.11 ENSRNOT00000012386
Fam214b
family with sequence similarity 214, member B
chr4_-_116786391 4.81 ENSRNOT00000086297
ENSRNOT00000091490
Exoc6b
exocyst complex component 6B
chr20_-_10912769 4.68 ENSRNOT00000051678
RGD1566085
similar to pyridoxal (pyridoxine, vitamin B6) kinase
chr2_+_122877286 4.67 ENSRNOT00000033080
Arse
arylsulfatase E
chr2_-_232117134 4.65 ENSRNOT00000030798
Alpk1
alpha-kinase 1
chr1_+_89017479 4.54 ENSRNOT00000038154
U2af1l4
U2 small nuclear RNA auxiliary factor 1-like 4
chr2_+_28460068 4.50 ENSRNOT00000066819
Foxd1
forkhead box D1
chr3_-_8432593 4.37 ENSRNOT00000090574
AC114363.1

chr4_+_7661558 4.26 ENSRNOT00000080229
Fam126a
family with sequence similarity 126, member A
chr10_+_90230441 4.12 ENSRNOT00000082722
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr12_+_2069959 3.99 ENSRNOT00000001298
Pnpla6
patatin-like phospholipase domain containing 6
chr10_-_46145548 3.88 ENSRNOT00000033483
Pld6
phospholipase D family, member 6
chr5_-_150506871 3.86 ENSRNOT00000086131
Trnau1ap
tRNA selenocysteine 1 associated protein 1
chr11_+_42858478 3.65 ENSRNOT00000002293
Arl6
ADP-ribosylation factor like GTPase 6
chr8_+_64364741 3.61 ENSRNOT00000082840
Celf6
CUGBP, Elav-like family member 6
chr13_-_79801561 3.60 ENSRNOT00000075936
Suco
SUN domain containing ossification factor
chr12_-_39641285 3.57 ENSRNOT00000001729
Anapc7
anaphase promoting complex subunit 7
chr20_-_3819200 3.40 ENSRNOT00000000542
ENSRNOT00000081486
Hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr12_-_19599374 3.32 ENSRNOT00000001849
Gpc2
glypican 2
chr17_+_15845931 3.22 ENSRNOT00000092083
Card19
caspase recruitment domain family, member 19
chr15_+_33069382 3.02 ENSRNOT00000060193
Mrpl52
mitochondrial ribosomal protein L52
chr4_+_7662019 2.79 ENSRNOT00000014023
Fam126a
family with sequence similarity 126, member A
chr1_-_89017290 2.78 ENSRNOT00000028438
Psenen
presenilin enhancer gamma secretase subunit
chr9_-_81879211 2.74 ENSRNOT00000085140
Rnf25
ring finger protein 25
chr12_+_2070365 2.70 ENSRNOT00000072952
Pnpla6
patatin-like phospholipase domain containing 6
chr3_-_130114770 2.56 ENSRNOT00000010638
Jag1
jagged 1
chr7_+_31784438 2.54 ENSRNOT00000010914
ENSRNOT00000010929
Ikbip
IKBKB interacting protein
chr1_-_19376301 2.45 ENSRNOT00000015547
Arhgap18
Rho GTPase activating protein 18
chr13_-_79801368 2.44 ENSRNOT00000075998
ENSRNOT00000084058
Suco
SUN domain containing ossification factor
chr13_-_79801112 2.43 ENSRNOT00000087323
ENSRNOT00000036483
Suco
SUN domain containing ossification factor
chr1_-_78212350 2.40 ENSRNOT00000071098
Inafm1
InaF-motif containing 1
chr12_+_19599834 2.31 ENSRNOT00000092039
ENSRNOT00000042006
Stag3
stromal antigen 3
chr4_-_51726212 2.18 ENSRNOT00000009261
Wasl
Wiskott-Aldrich syndrome-like
chr3_-_60795951 2.15 ENSRNOT00000002174
Atf2
activating transcription factor 2
chr2_-_260148589 2.15 ENSRNOT00000013238
Acadm
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr4_-_121565212 2.13 ENSRNOT00000088753
Chchd6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr6_-_102353403 2.11 ENSRNOT00000090407
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr13_+_44957014 2.01 ENSRNOT00000004878
Ubxn4
UBX domain protein 4
chr20_-_5533600 1.85 ENSRNOT00000072319
Cuta
cutA divalent cation tolerance homolog
chr7_+_11414446 1.77 ENSRNOT00000027441
Pias4
protein inhibitor of activated STAT, 4
chr20_-_5533448 1.77 ENSRNOT00000000568
Cuta
cutA divalent cation tolerance homolog
chr13_-_102643223 1.76 ENSRNOT00000003155
Hlx
H2.0-like homeobox
chr11_+_87522971 1.58 ENSRNOT00000043545
Smpd4
sphingomyelin phosphodiesterase 4
chr13_-_113817995 1.44 ENSRNOT00000057151
Cd46
CD46 molecule
chr1_-_261371508 1.43 ENSRNOT00000019978
Avpi1
arginine vasopressin-induced 1
chr10_+_56576428 1.42 ENSRNOT00000079237
ENSRNOT00000023291
Cldn7
claudin 7
chr9_-_43022998 1.37 ENSRNOT00000063781
ENSRNOT00000089843
Lman2l
lectin, mannose-binding 2-like
chr1_+_198210525 1.35 ENSRNOT00000026755
Ypel3
yippee-like 3
chr1_-_164814651 1.31 ENSRNOT00000024420
Neu3
neuraminidase 3
chr1_-_78573374 1.30 ENSRNOT00000090519
Arhgap35
Rho GTPase activating protein 35
chr6_-_108329464 1.19 ENSRNOT00000016040
Abcd4
ATP binding cassette subfamily D member 4
chr10_-_11035484 0.91 ENSRNOT00000077164
Hmox2
heme oxygenase 2
chr10_+_93354003 0.89 ENSRNOT00000008140
Mettl2b
methyltransferase like 2B
chr4_-_113497396 0.80 ENSRNOT00000079173
ENSRNOT00000067314
Pole4
DNA polymerase epsilon 4, accessory subunit
chr20_+_3351303 0.72 ENSRNOT00000080419
ENSRNOT00000001065
ENSRNOT00000086503
Atat1
alpha tubulin acetyltransferase 1
chr20_+_10265806 0.65 ENSRNOT00000001564
ENSRNOT00000086272
Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
chrX_-_65335987 0.52 ENSRNOT00000047128
AABR07038981.1

chr3_+_164274710 0.38 ENSRNOT00000012939
Snai1
snail family transcriptional repressor 1
chr7_+_117605050 0.23 ENSRNOT00000047380
Slc52a2
solute carrier family 52 member 2
chr20_-_49486550 0.07 ENSRNOT00000048270
ENSRNOT00000076541
Prdm1
PR/SET domain 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
3.1 9.3 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
2.1 8.5 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
2.1 8.2 GO:0042126 growth plate cartilage chondrocyte proliferation(GO:0003419) nitrate metabolic process(GO:0042126)
2.0 11.7 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.8 11.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.5 5.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.4 18.5 GO:0006527 arginine catabolic process(GO:0006527)
1.3 5.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
1.3 3.9 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
1.2 3.6 GO:1903445 protein transport from ciliary membrane to plasma membrane(GO:1903445)
1.1 4.5 GO:0072076 nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
1.0 7.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.9 5.2 GO:0038203 TORC2 signaling(GO:0038203)
0.9 2.6 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
0.7 2.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.7 2.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.7 8.3 GO:0072718 response to cisplatin(GO:0072718)
0.5 2.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.5 3.9 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.5 1.4 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.5 0.9 GO:0006788 heme oxidation(GO:0006788)
0.4 1.8 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.4 5.6 GO:1903830 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
0.4 3.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 8.2 GO:0030903 notochord development(GO:0030903)
0.4 1.8 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3 1.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.3 2.8 GO:0007220 Notch receptor processing(GO:0007220)
0.3 10.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.2 0.7 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.2 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.2 7.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 1.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 6.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 2.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 7.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 3.6 GO:0071625 vocalization behavior(GO:0071625)
0.2 6.7 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 1.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 2.1 GO:0042407 cristae formation(GO:0042407)
0.1 7.7 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.1 1.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 2.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 4.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 5.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 9.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 5.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 8.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 3.0 GO:0032543 mitochondrial translation(GO:0032543)
0.1 7.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 2.3 GO:0007129 synapsis(GO:0007129)
0.0 2.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 3.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 2.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 2.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 8.5 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.0 1.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.6 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 3.1 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
2.3 11.4 GO:0070695 FHF complex(GO:0070695)
0.8 2.3 GO:0000802 transverse filament(GO:0000802)
0.8 4.5 GO:0089701 U2AF(GO:0089701)
0.6 5.2 GO:0061700 GATOR2 complex(GO:0061700)
0.5 2.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 2.2 GO:0030478 actin cap(GO:0030478)
0.4 1.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.3 8.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 4.6 GO:0035253 ciliary rootlet(GO:0035253)
0.3 2.1 GO:0061617 MICOS complex(GO:0061617)
0.3 8.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 4.8 GO:0000145 exocyst(GO:0000145)
0.2 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.2 12.9 GO:0005581 collagen trimer(GO:0005581)
0.2 7.7 GO:0016592 mediator complex(GO:0016592)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 7.5 GO:0032420 stereocilium(GO:0032420)
0.1 2.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 17.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 12.5 GO:0043195 terminal bouton(GO:0043195)
0.1 2.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 3.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.8 GO:0005795 Golgi stack(GO:0005795)
0.0 5.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 15.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 17.6 GO:0005739 mitochondrion(GO:0005739)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.6 GO:0005929 cilium(GO:0005929)
0.0 1.6 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 18.5 GO:0016403 dimethylargininase activity(GO:0016403)
3.1 12.5 GO:0099510 calcium ion binding involved in regulation of cytosolic calcium ion concentration(GO:0099510)
1.9 5.8 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
1.7 8.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.4 8.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.1 11.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
1.1 3.4 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.9 7.7 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.7 4.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.5 5.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 9.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.5 4.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.4 1.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 11.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.4 5.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.4 5.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 6.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 11.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 10.0 GO:0005158 insulin receptor binding(GO:0005158)
0.2 8.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 4.5 GO:0008301 DNA binding, bending(GO:0008301)
0.2 8.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 3.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 2.6 GO:0005112 Notch binding(GO:0005112)
0.1 1.4 GO:0001848 complement binding(GO:0001848)
0.1 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 4.6 GO:0019894 kinesin binding(GO:0019894)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 3.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 3.9 GO:0000049 tRNA binding(GO:0000049)
0.0 3.6 GO:0005507 copper ion binding(GO:0005507)
0.0 11.0 GO:0019902 phosphatase binding(GO:0019902)
0.0 7.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 11.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.6 GO:0004620 phospholipase activity(GO:0004620)
0.0 13.5 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 3.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 5.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.2 2.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 3.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 2.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 2.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 5.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 4.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 3.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 2.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation