ISMARA results: Klf6

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Klf6_Patz1

Z-value: 1.62

Motif logo

Transcription factors associated with Klf6_Patz1

Gene Symbol	Gene ID	Gene Info
Klf6 NCBI RGD Ensembl	ENSRNOG00000016885	Kruppel-like factor 6
Patz1 NCBI RGD Ensembl	ENSRNOG00000018709	POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Klf6	rn6_v1_chr17_-_67904674_67904674	-0.27	1.3e-06	Click!
Patz1	rn6_v1_chr14_+_83510640_83510640	-0.05	3.4e-01	Click!

Activity profile of Klf6_Patz1 motif

Sorted Z-values of Klf6_Patz1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_20607507 Show fit	78.84	ENSRNOT00000000011	Cbln1 NCBI RGD Ensembl Show fit	cerebellin 1 precursor
chr1_-_198454914 Show fit	65.59	ENSRNOT00000049044	Prrt2 NCBI RGD Ensembl Show fit	proline-rich transmembrane protein 2
chr15_+_3936786 Show fit	59.84	ENSRNOT00000066163	Camk2g NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II gamma
chr20_-_48503898 Show fit	53.92	ENSRNOT00000073091	Wasf1 NCBI RGD Ensembl Show fit	WAS protein family, member 1
chr7_-_116607674 Show fit	52.64	ENSRNOT00000076014	Ly6h NCBI RGD Ensembl Show fit	lymphocyte antigen 6 complex, locus H
chr5_+_139783951 Show fit	52.17	ENSRNOT00000081333	Rims3 NCBI RGD Ensembl Show fit	regulating synaptic membrane exocytosis 3
chr10_-_85974644 Show fit	49.24	ENSRNOT00000006098 ENSRNOT00000082974	Cacnb1 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit beta 1
chr8_-_94564525 Show fit	47.29	ENSRNOT00000084437	Snap91 NCBI RGD Ensembl Show fit	synaptosomal-associated protein 91
chr9_+_73493027 Show fit	45.91	ENSRNOT00000074427 ENSRNOT00000089478	Unc80 NCBI RGD Ensembl Show fit	unc-80 homolog, NALCN activator
chr9_+_9961021 Show fit	45.03	ENSRNOT00000075767	Tubb4a NCBI RGD Ensembl Show fit	tubulin, beta 4A class IVa
chrX_-_38196060 Show fit	44.72	ENSRNOT00000006741 ENSRNOT00000006438	Sh3kbp1 NCBI RGD Ensembl Show fit	SH3 domain-containing kinase-binding protein 1
chr10_+_56627411 Show fit	43.92	ENSRNOT00000089108 ENSRNOT00000068493	Dlg4 NCBI RGD Ensembl Show fit	discs large MAGUK scaffold protein 4
chr9_+_17841410 Show fit	43.38	ENSRNOT00000031706	Tmem151b NCBI RGD Ensembl Show fit	transmembrane protein 151B
chr6_+_144384773 Show fit	41.75	ENSRNOT00000006942	Ptprn2 NCBI RGD Ensembl Show fit	protein tyrosine phosphatase, receptor type N2
chr1_-_220480132 Show fit	40.95	ENSRNOT00000027421	Cnih2 NCBI RGD Ensembl Show fit	cornichon family AMPA receptor auxiliary protein 2
chr7_-_116607408 Show fit	39.77	ENSRNOT00000076009 ENSRNOT00000056554	Ly6h NCBI RGD Ensembl Show fit	lymphocyte antigen 6 complex, locus H
chr10_+_56546710 Show fit	37.77	ENSRNOT00000023003	Ybx2 NCBI RGD Ensembl Show fit	Y box binding protein 2
chr18_+_83471342 Show fit	37.43	ENSRNOT00000019384	Neto1 NCBI RGD Ensembl Show fit	neuropilin and tolloid like 1
chr4_-_71713063 Show fit	37.07	ENSRNOT00000059447	Fam131b NCBI RGD Ensembl Show fit	family with sequence similarity 131, member B
chr10_+_39655455 Show fit	37.05	ENSRNOT00000058817	Acsl6 NCBI RGD Ensembl Show fit	acyl-CoA synthetase long-chain family member 6
chr7_-_136853957 Show fit	36.43	ENSRNOT00000008985	Nell2 NCBI RGD Ensembl Show fit	neural EGFL like 2
chr7_+_70364813 Show fit	36.05	ENSRNOT00000084012 ENSRNOT00000031230	Agap2 NCBI RGD Ensembl Show fit	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_+_83975367 Show fit	35.64	ENSRNOT00000058131	Camk2n2 NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr9_-_28972835 Show fit	35.50	ENSRNOT00000086967 ENSRNOT00000079684	Rims1 NCBI RGD Ensembl Show fit	regulating synaptic membrane exocytosis 1
chr1_+_198383201 Show fit	35.15	ENSRNOT00000037405	Sez6l2 NCBI RGD Ensembl Show fit	seizure related 6 homolog like 2
chr5_-_85123829 Show fit	34.35	ENSRNOT00000007578	Brinp1 NCBI RGD Ensembl Show fit	BMP/retinoic acid inducible neural specific 1
chr6_+_29977797 Show fit	33.73	ENSRNOT00000071784	Fkbp1b NCBI RGD Ensembl Show fit	FK506 binding protein 1B
chr9_+_16612433 Show fit	33.71	ENSRNOT00000023979	Klhdc3 NCBI RGD Ensembl Show fit	kelch domain containing 3
chr1_-_87155118 Show fit	33.45	ENSRNOT00000072441	AABR07002854.1 NCBI RGD Ensembl Show fit
chr1_+_80195532 Show fit	32.87	ENSRNOT00000022528	Rtn2 NCBI RGD Ensembl Show fit	reticulon 2
chr1_+_100297152 Show fit	32.86	ENSRNOT00000026100	Shank1 NCBI RGD Ensembl Show fit	SH3 and multiple ankyrin repeat domains 1
chr10_+_57278307 Show fit	32.86	ENSRNOT00000005612	Eno3 NCBI RGD Ensembl Show fit	enolase 3
chr20_+_12429315 Show fit	31.83	ENSRNOT00000001675	Pcbp3 NCBI RGD Ensembl Show fit	poly(rC) binding protein 3
chr2_+_121165137 Show fit	31.15	ENSRNOT00000016236	Sox2 NCBI RGD Ensembl Show fit	SRY box 2
chr1_+_101161252 Show fit	31.04	ENSRNOT00000028064 ENSRNOT00000064184	Slc17a7 NCBI RGD Ensembl Show fit	solute carrier family 17 member 7
chr1_+_221872220 Show fit	30.88	ENSRNOT00000028651	Nrxn2 NCBI RGD Ensembl Show fit	neurexin 2
chr6_+_127400585 Show fit	30.78	ENSRNOT00000087429	Ppp4r4 NCBI RGD Ensembl Show fit	protein phosphatase 4, regulatory subunit 4
chr13_-_98772968 Show fit	30.76	ENSRNOT00000057735	Stum NCBI RGD Ensembl Show fit	stum, mechanosensory transduction mediator homolog
chr1_+_173607101 Show fit	30.64	ENSRNOT00000074636	Tub NCBI RGD Ensembl Show fit	tubby bipartite transcription factor
chr3_+_161425988 Show fit	30.31	ENSRNOT00000065184	Slc12a5 NCBI RGD Ensembl Show fit	solute carrier family 12 member 5
chr15_-_33775109 Show fit	29.78	ENSRNOT00000033722	Jph4 NCBI RGD Ensembl Show fit	junctophilin 4
chr10_-_83332851 Show fit	29.22	ENSRNOT00000007133	Nxph3 NCBI RGD Ensembl Show fit	neurexophilin 3
chr9_+_82596355 Show fit	29.21	ENSRNOT00000065076	Speg NCBI RGD Ensembl Show fit	SPEG complex locus
chr20_+_5535432 Show fit	28.89	ENSRNOT00000040859	Syngap1 NCBI RGD Ensembl Show fit	synaptic Ras GTPase activating protein 1
chr18_+_16650806 Show fit	28.87	ENSRNOT00000093679 ENSRNOT00000041961 ENSRNOT00000093140	Fhod3 NCBI RGD Ensembl Show fit	formin homology 2 domain containing 3
chr7_-_59514939 Show fit	28.68	ENSRNOT00000085579	Kcnmb4 NCBI RGD Ensembl Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr8_-_23063041 Show fit	28.66	ENSRNOT00000018416	Elavl3 NCBI RGD Ensembl Show fit	ELAV like RNA binding protein 3
chr14_+_108826831 Show fit	28.38	ENSRNOT00000083146 ENSRNOT00000009421	Bcl11a NCBI RGD Ensembl Show fit	B-cell CLL/lymphoma 11A
chr7_-_136853154 Show fit	27.54	ENSRNOT00000087376	Nell2 NCBI RGD Ensembl Show fit	neural EGFL like 2
chr2_-_220101791 Show fit	27.33	ENSRNOT00000022905	Plppr5 NCBI RGD Ensembl Show fit	phospholipid phosphatase related 5
chr16_+_22250470 Show fit	27.17	ENSRNOT00000015799	Lzts1 NCBI RGD Ensembl Show fit	leucine zipper tumor suppressor 1
chrX_-_15707436 Show fit	27.16	ENSRNOT00000085907	Syp NCBI RGD Ensembl Show fit	synaptophysin
chr16_-_5795825 Show fit	27.09	ENSRNOT00000048043	Cacna2d3 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr4_-_180234804 Show fit	26.88	ENSRNOT00000070957	Bhlhe41 NCBI RGD Ensembl Show fit	basic helix-loop-helix family, member e41
chr6_-_27024129 Show fit	26.87	ENSRNOT00000012273	Dpysl5 NCBI RGD Ensembl Show fit	dihydropyrimidinase-like 5
chr18_+_28781349 Show fit	26.83	ENSRNOT00000026112	Psd2 NCBI RGD Ensembl Show fit	pleckstrin and Sec7 domain containing 2
chr18_+_31094965 Show fit	26.77	ENSRNOT00000026526	Rell2 NCBI RGD Ensembl Show fit	RELT-like 2
chr1_+_234252757 Show fit	26.72	ENSRNOT00000091814	Rorb NCBI RGD Ensembl Show fit	RAR-related orphan receptor B
chr2_+_206064394 Show fit	26.33	ENSRNOT00000077739	Syt6 NCBI RGD Ensembl Show fit	synaptotagmin 6
chr3_-_1924827 Show fit	26.30	ENSRNOT00000006162	Cacna1b NCBI RGD Ensembl Show fit	calcium voltage-gated channel subunit alpha1 B
chr13_-_90589466 Show fit	26.17	ENSRNOT00000070812	Pea15 NCBI RGD Ensembl Show fit	phosphoprotein enriched in astrocytes 15
chr6_-_94980004 Show fit	26.14	ENSRNOT00000006373	Rtn1 NCBI RGD Ensembl Show fit	reticulon 1
chr1_+_221792221 Show fit	25.81	ENSRNOT00000054828	Nrxn2 NCBI RGD Ensembl Show fit	neurexin 2
chr7_-_70842405 Show fit	25.80	ENSRNOT00000047449	Nxph4 NCBI RGD Ensembl Show fit	neurexophilin 4
chr7_-_140483693 Show fit	25.30	ENSRNOT00000089060	Ddn NCBI RGD Ensembl Show fit	dendrin
chr8_-_12993651 Show fit	25.21	ENSRNOT00000033932	Kdm4d NCBI RGD Ensembl Show fit	lysine demethylase 4D
chr11_+_86512797 Show fit	24.84	ENSRNOT00000051680	Gp1bb NCBI RGD Ensembl Show fit	glycoprotein Ib platelet beta subunit
chr5_-_109621170 Show fit	24.64	ENSRNOT00000093007	Elavl2 NCBI RGD Ensembl Show fit	ELAV like RNA binding protein 2
chr8_+_62723788 Show fit	24.56	ENSRNOT00000010620	Sema7a NCBI RGD Ensembl Show fit	semaphorin 7A (John Milton Hagen blood group)
chr4_-_157381105 Show fit	24.56	ENSRNOT00000021670	Gpr162 NCBI RGD Ensembl Show fit	G protein-coupled receptor 162
chr19_-_9801942 Show fit	24.35	ENSRNOT00000051414 ENSRNOT00000017494	Ndrg4 NCBI RGD Ensembl Show fit	NDRG family member 4
chr2_+_113984646 Show fit	24.30	ENSRNOT00000016799	Tnik NCBI RGD Ensembl Show fit	TRAF2 and NCK interacting kinase
chr5_+_156876706 Show fit	24.04	ENSRNOT00000021864	Camk2n1 NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr20_+_19318250 Show fit	23.64	ENSRNOT00000000299	Phyhipl NCBI RGD Ensembl Show fit	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr5_-_17061837 Show fit	23.48	ENSRNOT00000011892	Penk NCBI RGD Ensembl Show fit	proenkephalin
chr4_+_56674832 Show fit	23.46	ENSRNOT00000060309	Ccdc136 NCBI RGD Ensembl Show fit	coiled-coil domain containing 136
chr7_+_133400485 Show fit	22.89	ENSRNOT00000006219	Cntn1 NCBI RGD Ensembl Show fit	contactin 1
chr9_+_16862248 Show fit	22.71	ENSRNOT00000080104 ENSRNOT00000024824	Ttbk1 NCBI RGD Ensembl Show fit	tau tubulin kinase 1
chr5_-_101588001 Show fit	22.53	ENSRNOT00000016130	Psip1 NCBI RGD Ensembl Show fit	PC4 and SFRS1 interacting protein 1
chrX_-_123601100 Show fit	22.48	ENSRNOT00000092546 ENSRNOT00000092301	Sept6 NCBI RGD Ensembl Show fit	septin 6
chr1_+_219348721 Show fit	22.46	ENSRNOT00000025084	Pitpnm1 NCBI RGD Ensembl Show fit	phosphatidylinositol transfer protein, membrane-associated 1
chr19_+_25526751 Show fit	22.36	ENSRNOT00000083448	Cacna1a NCBI RGD Ensembl Show fit	calcium voltage-gated channel subunit alpha1 A
chr5_-_144779212 Show fit	22.35	ENSRNOT00000016230	Ncdn NCBI RGD Ensembl Show fit	neurochondrin
chr8_-_130429132 Show fit	22.23	ENSRNOT00000026261	Hhatl NCBI RGD Ensembl Show fit	hedgehog acyltransferase-like
chr1_-_220136470 Show fit	21.91	ENSRNOT00000026812	Actn3 NCBI RGD Ensembl Show fit	actinin alpha 3
chr4_-_155116154 Show fit	21.85	ENSRNOT00000020529	Phc1 NCBI RGD Ensembl Show fit	polyhomeotic homolog 1
chr1_-_222182721 Show fit	21.75	ENSRNOT00000078008	Tex40 NCBI RGD Ensembl Show fit	testis expressed 40
chr13_+_51034256 Show fit	21.66	ENSRNOT00000004528 ENSRNOT00000046854 ENSRNOT00000087320	Mybph NCBI RGD Ensembl Show fit	myosin binding protein H
chr9_+_82674202 Show fit	21.60	ENSRNOT00000027208	Tmem198 NCBI RGD Ensembl Show fit	transmembrane protein 198
chr1_-_64350338 Show fit	21.57	ENSRNOT00000078444	Cacng8 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 8
chr16_-_73152921 Show fit	21.43	ENSRNOT00000048602	Zmat4 NCBI RGD Ensembl Show fit	zinc finger, matrin type 4
chr7_-_107009330 Show fit	21.43	ENSRNOT00000074573	Kcnq3 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily Q member 3
chr6_-_99783047 Show fit	21.36	ENSRNOT00000009028	Sptb NCBI RGD Ensembl Show fit	spectrin, beta, erythrocytic
chr1_-_72727112 Show fit	21.35	ENSRNOT00000031172	Brsk1 NCBI RGD Ensembl Show fit	BR serine/threonine kinase 1
chr9_+_82120059 Show fit	21.26	ENSRNOT00000057368	Cdk5r2 NCBI RGD Ensembl Show fit	cyclin-dependent kinase 5 regulatory subunit 2
chr3_+_56861396 Show fit	21.17	ENSRNOT00000000008 ENSRNOT00000084375	Gad1 NCBI RGD Ensembl Show fit	glutamate decarboxylase 1
chr3_-_3476215 Show fit	21.11	ENSRNOT00000024352	Ubac1 NCBI RGD Ensembl Show fit	UBA domain containing 1
chr3_-_105470475 Show fit	20.93	ENSRNOT00000011078	Gjd2 NCBI RGD Ensembl Show fit	gap junction protein, delta 2
chr17_+_10384511 Show fit	20.91	ENSRNOT00000024357	Sncb NCBI RGD Ensembl Show fit	synuclein, beta
chr3_-_66417741 Show fit	20.82	ENSRNOT00000007662	Neurod1 NCBI RGD Ensembl Show fit	neuronal differentiation 1
chr13_+_40300039 Show fit	20.75	ENSRNOT00000049137	AABR07020786.1 NCBI RGD Ensembl Show fit
chr5_-_58019836 Show fit	20.62	ENSRNOT00000066977	Enho NCBI RGD Ensembl Show fit	energy homeostasis associated
chr1_+_211423022 Show fit	20.60	ENSRNOT00000029587	Dpysl4 NCBI RGD Ensembl Show fit	dihydropyrimidinase-like 4
chr3_-_151032302 Show fit	20.51	ENSRNOT00000025315	Ggt7 NCBI RGD Ensembl Show fit	gamma-glutamyltransferase 7
chr20_-_1980101 Show fit	20.45	ENSRNOT00000084582 ENSRNOT00000085050 ENSRNOT00000082545 ENSRNOT00000088396	Gabbr1 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type B receptor subunit 1
chr2_+_174542667 Show fit	20.36	ENSRNOT00000076793	Fstl5 NCBI RGD Ensembl Show fit	follistatin-like 5
chr7_+_12043794 Show fit	20.36	ENSRNOT00000039813	Atp8b3 NCBI RGD Ensembl Show fit	ATPase phospholipid transporting 8B3
chr3_-_150062311 Show fit	20.34	ENSRNOT00000022115	E2f1 NCBI RGD Ensembl Show fit	E2F transcription factor 1
chr7_+_78092037 Show fit	20.32	ENSRNOT00000050753	Rims2 NCBI RGD Ensembl Show fit	regulating synaptic membrane exocytosis 2
chr3_+_111545007 Show fit	20.28	ENSRNOT00000007247	Itpka NCBI RGD Ensembl Show fit	inositol-trisphosphate 3-kinase A
chr3_+_41019898 Show fit	20.25	ENSRNOT00000007335	Kcnj3 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 3
chr13_-_51183269 Show fit	20.24	ENSRNOT00000039540	Ppfia4 NCBI RGD Ensembl Show fit	PTPRF interacting protein alpha 4
chr13_+_48607308 Show fit	20.17	ENSRNOT00000063882	Slc41a1 NCBI RGD Ensembl Show fit	solute carrier family 41 member 1
chr13_-_91872954 Show fit	20.07	ENSRNOT00000004613 ENSRNOT00000079263	Cadm3 NCBI RGD Ensembl Show fit	cell adhesion molecule 3
chr4_-_152380184 Show fit	20.05	ENSRNOT00000091473	Erc1 NCBI RGD Ensembl Show fit	ELKS/RAB6-interacting/CAST family member 1
chr3_+_56862691 Show fit	19.92	ENSRNOT00000087712	Gad1 NCBI RGD Ensembl Show fit	glutamate decarboxylase 1
chr5_-_105582375 Show fit	19.81	ENSRNOT00000083373	Slc24a2 NCBI RGD Ensembl Show fit	solute carrier family 24 member 2
chr5_+_147323240 Show fit	19.78	ENSRNOT00000047152	Fndc5 NCBI RGD Ensembl Show fit	fibronectin type III domain containing 5
chr8_+_48422036 Show fit	19.74	ENSRNOT00000036051	Usp2 NCBI RGD Ensembl Show fit	ubiquitin specific peptidase 2
chr4_+_21317695 Show fit	19.72	ENSRNOT00000007572	Grm3 NCBI RGD Ensembl Show fit	glutamate metabotropic receptor 3
chr5_-_101588598 Show fit	19.65	ENSRNOT00000082239	Psip1 NCBI RGD Ensembl Show fit	PC4 and SFRS1 interacting protein 1
chr1_+_266953139 Show fit	19.61	ENSRNOT00000054696	Neurl1 NCBI RGD Ensembl Show fit	neuralized E3 ubiquitin protein ligase 1
chr10_+_67862054 Show fit	19.55	ENSRNOT00000031746	Cdk5r1 NCBI RGD Ensembl Show fit	cyclin-dependent kinase 5 regulatory subunit 1
chr2_-_148050423 Show fit	19.53	ENSRNOT00000064506 ENSRNOT00000023469	LOC100909840 NCBI RGD Ensembl Show fit	profilin-2-like
chr1_-_64405149 Show fit	19.43	ENSRNOT00000089944	Cacng7 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 7
chr12_+_19599834 Show fit	19.29	ENSRNOT00000092039 ENSRNOT00000042006	Stag3 NCBI RGD Ensembl Show fit	stromal antigen 3
chr12_+_2534212 Show fit	19.16	ENSRNOT00000001399	Ctxn1 NCBI RGD Ensembl Show fit	cortexin 1
chr18_-_38088457 Show fit	18.98	ENSRNOT00000077814	Jakmip2 NCBI RGD Ensembl Show fit	janus kinase and microtubule interacting protein 2
chr10_-_56444847 Show fit	18.89	ENSRNOT00000056872 ENSRNOT00000092662	Nlgn2 NCBI RGD Ensembl Show fit	neuroligin 2
chr8_+_49737798 Show fit	18.82	ENSRNOT00000022476	Dscaml1 NCBI RGD Ensembl Show fit	DS cell adhesion molecule-like 1
chr1_-_94494980 Show fit	18.82	ENSRNOT00000020014	Ccne1 NCBI RGD Ensembl Show fit	cyclin E1
chr9_-_17114177 Show fit	18.66	ENSRNOT00000061185	Lrrc73 NCBI RGD Ensembl Show fit	leucine rich repeat containing 73
chr2_+_189106039 Show fit	18.58	ENSRNOT00000028210	Ube2q1 NCBI RGD Ensembl Show fit	ubiquitin conjugating enzyme E2 Q1
chr11_+_86516390 Show fit	18.57	ENSRNOT00000041168	Gp1bb NCBI RGD Ensembl Show fit	glycoprotein Ib platelet beta subunit
chr2_+_113984824 Show fit	18.29	ENSRNOT00000086399	Tnik NCBI RGD Ensembl Show fit	TRAF2 and NCK interacting kinase
chr8_+_64364741 Show fit	18.21	ENSRNOT00000082840	Celf6 NCBI RGD Ensembl Show fit	CUGBP, Elav-like family member 6
chr17_-_18592750 Show fit	18.12	ENSRNOT00000065742	Cap2 NCBI RGD Ensembl Show fit	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr13_-_111765944 Show fit	18.12	ENSRNOT00000073041	Syt14 NCBI RGD Ensembl Show fit	synaptotagmin 14
chr17_+_9679628 Show fit	18.07	ENSRNOT00000019569 ENSRNOT00000019393	Dbn1 NCBI RGD Ensembl Show fit	drebrin 1
chr10_+_92191718 Show fit	18.06	ENSRNOT00000006764 ENSRNOT00000032941	Crhr1 NCBI RGD Ensembl Show fit	corticotropin releasing hormone receptor 1
chr10_-_31419235 Show fit	17.99	ENSRNOT00000059496	Cyfip2 NCBI RGD Ensembl Show fit	cytoplasmic FMR1 interacting protein 2
chr9_+_99998275 Show fit	17.99	ENSRNOT00000074395	Gpc1 NCBI RGD Ensembl Show fit	glypican 1
chr3_+_148510779 Show fit	17.95	ENSRNOT00000012156	Xkr7 NCBI RGD Ensembl Show fit	XK related 7
chr10_-_108691367 Show fit	17.90	ENSRNOT00000005067	Nptx1 NCBI RGD Ensembl Show fit	neuronal pentraxin 1
chr8_+_22947152 Show fit	17.88	ENSRNOT00000016790	Plppr2 NCBI RGD Ensembl Show fit	phospholipid phosphatase related 2
chr20_-_1984737 Show fit	17.87	ENSRNOT00000040232 ENSRNOT00000051634 ENSRNOT00000079445	Gabbr1 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type B receptor subunit 1
chr7_+_130431213 Show fit	17.80	ENSRNOT00000055792	Mapk8ip2 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase 8 interacting protein 2
chr2_+_206064179 Show fit	17.74	ENSRNOT00000025953	Syt6 NCBI RGD Ensembl Show fit	synaptotagmin 6
chr11_-_83905889 Show fit	17.70	ENSRNOT00000075606	Fam131a NCBI RGD Ensembl Show fit	family with sequence similarity 131, member A
chr5_+_58393603 Show fit	17.68	ENSRNOT00000080082	Dnajb5 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member B5
chr11_-_82884660 Show fit	17.67	ENSRNOT00000073526	LOC100912498 NCBI RGD Ensembl Show fit	protein FAM131A-like
chr18_+_56193978 Show fit	17.62	ENSRNOT00000041533 ENSRNOT00000080177	Camk2a NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II alpha
chr1_-_81946714 Show fit	17.47	ENSRNOT00000027578	Grik5 NCBI RGD Ensembl Show fit	glutamate ionotropic receptor kainate type subunit 5
chr1_-_215836641 Show fit	17.46	ENSRNOT00000080246	Igf2 NCBI RGD Ensembl Show fit	insulin-like growth factor 2
chr2_+_34186091 Show fit	17.46	ENSRNOT00000016129	Sgtb NCBI RGD Ensembl Show fit	small glutamine rich tetratricopeptide repeat containing beta
chr1_-_88112683 Show fit	17.44	ENSRNOT00000090615	Spred3 NCBI RGD Ensembl Show fit	sprouty-related, EVH1 domain containing 3
chr10_-_14056169 Show fit	17.42	ENSRNOT00000017833	Syngr3 NCBI RGD Ensembl Show fit	synaptogyrin 3
chr9_+_38297322 Show fit	17.41	ENSRNOT00000078157 ENSRNOT00000088824	Bend6 NCBI RGD Ensembl Show fit	BEN domain containing 6
chrX_-_152641679 Show fit	17.40	ENSRNOT00000080277	Gabra3 NCBI RGD Ensembl Show fit	gamma-aminobutyric acid type A receptor alpha3 subunit
chr1_-_84491466 Show fit	17.36	ENSRNOT00000034609	Map3k10 NCBI RGD Ensembl Show fit	mitogen activated protein kinase kinase kinase 10
chr1_+_101783621 Show fit	17.29	ENSRNOT00000067679	Lmtk3 NCBI RGD Ensembl Show fit	lemur tyrosine kinase 3
chr19_-_11669578 Show fit	17.13	ENSRNOT00000026373	Gnao1 NCBI RGD Ensembl Show fit	G protein subunit alpha o1
chr1_-_165680176 Show fit	17.10	ENSRNOT00000025245 ENSRNOT00000082697	Plekhb1 NCBI RGD Ensembl Show fit	pleckstrin homology domain containing B1
chr3_+_168345152 Show fit	17.07	ENSRNOT00000017654	Dok5 NCBI RGD Ensembl Show fit	docking protein 5
chr11_+_75905443 Show fit	17.04	ENSRNOT00000002650	Fgf12 NCBI RGD Ensembl Show fit	fibroblast growth factor 12
chr1_+_221801524 Show fit	16.97	ENSRNOT00000031227	Nrxn2 NCBI RGD Ensembl Show fit	neurexin 2
chr15_-_28696122 Show fit	16.89	ENSRNOT00000060467	Rab2b NCBI RGD Ensembl Show fit	RAB2B, member RAS oncogene family
chr7_+_123510804 Show fit	16.83	ENSRNOT00000010491	Sept3 NCBI RGD Ensembl Show fit	septin 3
chr7_-_70552897 Show fit	16.83	ENSRNOT00000080594	Kif5a NCBI RGD Ensembl Show fit	kinesin family member 5A
chr14_-_78902063 Show fit	16.82	ENSRNOT00000088469	Ppp2r2c NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B, gamma
chr1_-_90685257 Show fit	16.81	ENSRNOT00000037700	Chst8 NCBI RGD Ensembl Show fit	carbohydrate sulfotransferase 8
chr3_+_113818872 Show fit	16.79	ENSRNOT00000044158	Casc4 NCBI RGD Ensembl Show fit	cancer susceptibility candidate 4
chr8_-_117382715 Show fit	16.78	ENSRNOT00000027466	P4htm NCBI RGD Ensembl Show fit	prolyl 4-hydroxylase, transmembrane
chr8_+_71216178 Show fit	16.78	ENSRNOT00000021372	Oaz2 NCBI RGD Ensembl Show fit	ornithine decarboxylase antizyme 2
chr12_-_30566032 Show fit	16.68	ENSRNOT00000093378	Gbas NCBI RGD Ensembl Show fit	glioblastoma amplified sequence
chr10_+_89376530 Show fit	16.68	ENSRNOT00000028089	Rnd2 NCBI RGD Ensembl Show fit	Rho family GTPase 2
chr2_+_239415046 Show fit	16.66	ENSRNOT00000072196	Cxxc4 NCBI RGD Ensembl Show fit	CXXC finger protein 4
chr1_+_241594565 Show fit	16.55	ENSRNOT00000020123	Apba1 NCBI RGD Ensembl Show fit	amyloid beta precursor protein binding family A member 1
chr2_-_147959567 Show fit	16.52	ENSRNOT00000063986	LOC100909840 NCBI RGD Ensembl Show fit	profilin-2-like
chr3_+_177225737 Show fit	16.51	ENSRNOT00000045845	Oprl1 NCBI RGD Ensembl Show fit	opioid related nociceptin receptor 1
chr5_+_58393233 Show fit	16.49	ENSRNOT00000000142	Dnajb5 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member B5
chr9_+_117538346 Show fit	16.41	ENSRNOT00000022849	Epb41l3 NCBI RGD Ensembl Show fit	erythrocyte membrane protein band 4.1-like 3
chr13_+_52976507 Show fit	16.38	ENSRNOT00000090599 ENSRNOT00000011324	Kif21b NCBI RGD Ensembl Show fit	kinesin family member 21B
chr3_-_143063983 Show fit	16.37	ENSRNOT00000006329	Napb NCBI RGD Ensembl Show fit	NSF attachment protein beta
chr5_-_133959447 Show fit	16.36	ENSRNOT00000011985	Cyp4x1 NCBI RGD Ensembl Show fit	cytochrome P450, family 4, subfamily x, polypeptide 1
chr1_+_105349069 Show fit	16.25	ENSRNOT00000056030	Nell1 NCBI RGD Ensembl Show fit	neural EGFL like 1
chr5_+_43603043 Show fit	16.19	ENSRNOT00000009899	Epha7 NCBI RGD Ensembl Show fit	Eph receptor A7
chr10_+_13854339 Show fit	16.17	ENSRNOT00000004486 ENSRNOT00000043951	Caskin1 NCBI RGD Ensembl Show fit	CASK interacting protein 1
chr6_+_64297888 Show fit	16.15	ENSRNOT00000050222 ENSRNOT00000083088 ENSRNOT00000093147	Nrcam NCBI RGD Ensembl Show fit	neuronal cell adhesion molecule
chrX_-_32355296 Show fit	16.14	ENSRNOT00000081652 ENSRNOT00000065075	Ap1s2 NCBI RGD Ensembl Show fit	adaptor-related protein complex 1, sigma 2 subunit
chr1_+_199196059 Show fit	16.11	ENSRNOT00000090428	Fbxl19 NCBI RGD Ensembl Show fit	F-box and leucine-rich repeat protein 19
chr8_-_58542844 Show fit	16.07	ENSRNOT00000012041	Elmod1 NCBI RGD Ensembl Show fit	ELMO domain containing 1
chr3_-_11885311 Show fit	16.06	ENSRNOT00000021189 ENSRNOT00000021178	Stxbp1 NCBI RGD Ensembl Show fit	syntaxin binding protein 1
chr10_-_109224370 Show fit	16.05	ENSRNOT00000005839	Aatk NCBI RGD Ensembl Show fit	apoptosis-associated tyrosine kinase
chr3_-_150064438 Show fit	15.98	ENSRNOT00000086933	E2f1 NCBI RGD Ensembl Show fit	E2F transcription factor 1
chr19_-_26053762 Show fit	15.98	ENSRNOT00000004646	MAST1 NCBI RGD Ensembl Show fit	microtubule associated serine/threonine kinase 1
chr1_-_197590277 Show fit	15.93	ENSRNOT00000022502 ENSRNOT00000043433	Xpo6 NCBI RGD Ensembl Show fit	exportin 6
chr5_-_40237591 Show fit	15.72	ENSRNOT00000011393	Fut9 NCBI RGD Ensembl Show fit	fucosyltransferase 9
chr6_+_44009872 Show fit	15.68	ENSRNOT00000082657	Mboat2 NCBI RGD Ensembl Show fit	membrane bound O-acyltransferase domain containing 2
chr9_-_15306465 Show fit	15.66	ENSRNOT00000019404	Frs3 NCBI RGD Ensembl Show fit	fibroblast growth factor receptor substrate 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf6_Patz1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.4	92.6	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
15.0	45.1	GO:0031632	positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
13.8	41.5	GO:0051867	general adaptation syndrome, behavioral process(GO:0051867)
12.5	37.4	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
12.5	37.4	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
12.3	37.0	GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
12.3	61.5	GO:0098970	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
11.0	65.7	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
10.7	32.0	GO:1903860	negative regulation of dendrite extension(GO:1903860)
10.2	40.8	GO:0021586	pons maturation(GO:0021586)
9.2	46.0	GO:1902162	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
9.0	71.9	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
8.9	44.4	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
8.8	44.1	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
8.7	17.5	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
8.4	25.2	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
8.4	25.1	GO:0060082	eye blink reflex(GO:0060082)
8.2	41.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
8.2	32.9	GO:0050893	sensory processing(GO:0050893)
8.1	24.3	GO:0050883	medulla oblongata development(GO:0021550) musculoskeletal movement, spinal reflex action(GO:0050883)
8.0	24.1	GO:0021905	pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
7.3	29.4	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
7.3	21.9	GO:0033123	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of purine nucleotide catabolic process(GO:0033123)
7.3	21.9	GO:1902303	negative regulation of potassium ion export(GO:1902303)
7.1	85.5	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
6.8	13.6	GO:0033693	neurofilament bundle assembly(GO:0033693)
6.8	47.3	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
6.8	33.8	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
6.7	26.7	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
6.5	39.3	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
6.4	12.9	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
6.3	69.4	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
6.3	25.1	GO:0044211	CTP salvage(GO:0044211)
6.1	30.4	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
6.1	18.2	GO:0010643	cell communication by chemical coupling(GO:0010643)
6.0	6.0	GO:0008355	olfactory learning(GO:0008355)
5.7	28.3	GO:0000160	phosphorelay signal transduction system(GO:0000160)
5.6	33.9	GO:0021759	globus pallidus development(GO:0021759)
5.6	16.8	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
5.6	16.8	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
5.5	27.6	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
5.4	10.9	GO:1900453	negative regulation of long term synaptic depression(GO:1900453)
5.4	27.1	GO:0060023	soft palate development(GO:0060023)
5.3	10.5	GO:0097113	AMPA glutamate receptor clustering(GO:0097113)
5.1	30.6	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
5.0	10.0	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
5.0	14.9	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
5.0	5.0	GO:0043578	nuclear matrix organization(GO:0043578)
4.9	39.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
4.9	9.8	GO:0099525	presynaptic dense core granule exocytosis(GO:0099525)
4.9	39.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
4.7	85.4	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
4.7	23.7	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
4.7	14.2	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
4.6	41.8	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
4.6	59.6	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
4.5	157.7	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
4.5	4.5	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151)
4.5	8.9	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
4.5	8.9	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
4.5	26.8	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
4.4	22.2	GO:1903059	regulation of protein lipidation(GO:1903059)
4.4	8.9	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
4.4	13.3	GO:0060300	regulation of cytokine activity(GO:0060300) fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
4.4	48.0	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
4.3	47.6	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
4.3	21.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
4.3	12.8	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
4.2	4.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
4.2	12.6	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822)
4.2	33.4	GO:0006751	glutathione catabolic process(GO:0006751)
4.2	12.5	GO:0051935	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
4.2	12.5	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
4.1	16.5	GO:1904059	regulation of locomotor rhythm(GO:1904059)
4.1	12.2	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
4.1	8.1	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
4.0	16.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
4.0	19.9	GO:0061743	motor learning(GO:0061743)
3.9	7.9	GO:1901079	positive regulation of relaxation of muscle(GO:1901079)
3.9	27.5	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
3.9	7.9	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
3.9	15.6	GO:0042339	keratan sulfate metabolic process(GO:0042339)
3.9	11.7	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
3.9	109.4	GO:1903831	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
3.9	15.6	GO:0072709	cellular response to sorbitol(GO:0072709)
3.9	11.6	GO:0030576	Cajal body organization(GO:0030576)
3.8	15.4	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
3.7	14.9	GO:0010615	positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
3.7	22.1	GO:0010045	response to nickel cation(GO:0010045)
3.7	62.6	GO:0050884	neuromuscular process controlling posture(GO:0050884)
3.6	10.8	GO:2000474	regulation of opioid receptor signaling pathway(GO:2000474)
3.6	17.9	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
3.6	7.1	GO:0099543	retrograde trans-synaptic signaling(GO:0098917) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
3.6	46.3	GO:0007614	short-term memory(GO:0007614)
3.6	10.7	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
3.5	10.6	GO:0046103	inosine biosynthetic process(GO:0046103)
3.5	10.4	GO:0060988	lipid tube assembly(GO:0060988)
3.5	10.4	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
3.4	17.0	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
3.4	10.1	GO:0071929	alpha-tubulin acetylation(GO:0071929)
3.4	20.2	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
3.4	13.4	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
3.3	46.8	GO:0007256	activation of JNKK activity(GO:0007256)
3.3	13.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
3.3	22.8	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
3.3	13.0	GO:0030043	actin filament fragmentation(GO:0030043)
3.2	12.6	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
3.1	12.5	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
3.0	12.0	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.0	33.1	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
2.9	26.4	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
2.9	14.6	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
2.9	29.0	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
2.9	26.0	GO:2001135	regulation of endocytic recycling(GO:2001135)
2.9	8.6	GO:1903596	regulation of gap junction assembly(GO:1903596)
2.8	8.5	GO:2000688	positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
2.8	8.4	GO:1902047	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
2.8	11.2	GO:0071802	negative regulation of podosome assembly(GO:0071802)
2.8	2.8	GO:0010996	response to auditory stimulus(GO:0010996)
2.8	8.3	GO:0032423	regulation of mismatch repair(GO:0032423)
2.7	19.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
2.7	18.6	GO:0070459	prolactin secretion(GO:0070459)
2.6	18.2	GO:0071625	vocalization behavior(GO:0071625)
2.6	15.5	GO:2001025	positive regulation of response to drug(GO:2001025)
2.6	15.4	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
2.6	33.4	GO:0005513	detection of calcium ion(GO:0005513)
2.6	35.8	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
2.5	20.2	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.5	27.7	GO:0046548	retinal rod cell development(GO:0046548)
2.5	9.9	GO:0033292	T-tubule organization(GO:0033292)
2.5	19.8	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
2.5	2.5	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
2.5	32.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
2.5	7.4	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
2.5	9.8	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
2.4	49.0	GO:0060074	synapse maturation(GO:0060074)
2.4	51.4	GO:1903861	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
2.4	4.9	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
2.4	17.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
2.4	7.2	GO:0072054	chemoattraction of axon(GO:0061642) renal outer medulla development(GO:0072054)
2.4	9.5	GO:1902534	single-organism membrane invagination(GO:1902534)
2.4	14.2	GO:0050915	sensory perception of sour taste(GO:0050915)
2.4	2.4	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
2.3	28.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
2.3	11.7	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
2.3	7.0	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
2.3	6.9	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
2.3	13.8	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.3	36.7	GO:0045475	locomotor rhythm(GO:0045475)
2.3	4.6	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
2.3	9.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
2.3	6.8	GO:0006435	prolyl-tRNA aminoacylation(GO:0006433) threonyl-tRNA aminoacylation(GO:0006435)
2.3	6.8	GO:0001661	conditioned taste aversion(GO:0001661)
2.2	33.7	GO:0007252	I-kappaB phosphorylation(GO:0007252)
2.2	11.2	GO:0002091	negative regulation of receptor internalization(GO:0002091)
2.2	24.6	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
2.2	20.0	GO:0035608	protein deglutamylation(GO:0035608)
2.2	4.4	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.2	8.8	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
2.2	4.3	GO:0090427	activation of meiosis(GO:0090427)
2.1	6.4	GO:0051037	regulation of transcription involved in meiotic cell cycle(GO:0051037)
2.1	12.5	GO:0042989	sequestering of actin monomers(GO:0042989)
2.0	8.2	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
2.0	2.0	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
2.0	8.1	GO:0048691	positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
2.0	8.0	GO:0050975	sensory perception of touch(GO:0050975)
2.0	12.0	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
2.0	7.9	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
2.0	9.9	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
2.0	5.9	GO:0006083	acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
1.9	13.6	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
1.9	34.7	GO:0001675	acrosome assembly(GO:0001675)
1.9	7.7	GO:0016554	cytidine to uridine editing(GO:0016554)
1.9	38.4	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
1.9	7.7	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
1.9	3.7	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
1.9	11.2	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
1.9	16.8	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
1.8	9.2	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.8	11.0	GO:0042908	xenobiotic transport(GO:0042908)
1.8	5.5	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
1.8	21.8	GO:0048681	negative regulation of axon regeneration(GO:0048681)
1.8	5.4	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.8	86.0	GO:0021762	substantia nigra development(GO:0021762)
1.8	7.1	GO:0070560	protein secretion by platelet(GO:0070560)
1.8	17.8	GO:0035524	proline transmembrane transport(GO:0035524)
1.8	5.3	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
1.8	8.8	GO:0035095	behavioral response to nicotine(GO:0035095)
1.8	24.6	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
1.7	5.2	GO:0018343	protein farnesylation(GO:0018343)
1.7	12.2	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
1.7	5.1	GO:0002380	immunoglobulin secretion involved in immune response(GO:0002380)
1.7	5.1	GO:0042441	eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
1.7	13.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
1.7	8.3	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
1.7	8.3	GO:0061709	reticulophagy(GO:0061709)
1.6	21.4	GO:0060081	membrane hyperpolarization(GO:0060081)
1.6	22.6	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
1.6	9.6	GO:0033564	anterior/posterior axon guidance(GO:0033564)
1.6	17.4	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
1.6	4.7	GO:0010265	SCF complex assembly(GO:0010265)
1.6	4.7	GO:0038203	TORC2 signaling(GO:0038203)
1.6	39.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.6	9.4	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
1.6	4.7	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.6	4.7	GO:0038003	opioid receptor signaling pathway(GO:0038003)
1.5	13.9	GO:2000774	positive regulation of cellular senescence(GO:2000774)
1.5	9.2	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.5	3.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
1.5	28.9	GO:0055003	cardiac myofibril assembly(GO:0055003)
1.5	22.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.5	6.0	GO:0072697	protein localization to cell cortex(GO:0072697)
1.5	6.0	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
1.5	4.4	GO:0038128	ERBB2 signaling pathway(GO:0038128)
1.5	4.4	GO:0006680	glucosylceramide catabolic process(GO:0006680)
1.5	1.5	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.5	7.3	GO:0071313	cellular response to caffeine(GO:0071313)
1.5	37.9	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
1.4	7.2	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.4	7.2	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
1.4	21.6	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
1.4	4.3	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112) fatty-acyl-CoA catabolic process(GO:0036115)
1.4	9.9	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
1.4	4.2	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
1.4	7.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
1.4	2.8	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.4	14.0	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
1.4	2.8	GO:0099545	trans-synaptic signaling by trans-synaptic complex(GO:0099545)
1.4	4.1	GO:0060019	radial glial cell differentiation(GO:0060019)
1.4	9.6	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
1.4	1.4	GO:0010616	negative regulation of cardiac muscle adaptation(GO:0010616)
1.4	16.4	GO:0001547	antral ovarian follicle growth(GO:0001547)
1.4	12.2	GO:0018298	protein-chromophore linkage(GO:0018298)
1.4	12.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.4	9.5	GO:0007021	tubulin complex assembly(GO:0007021)
1.3	2.7	GO:0036394	amylase secretion(GO:0036394)
1.3	4.0	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
1.3	29.6	GO:0000188	inactivation of MAPK activity(GO:0000188)
1.3	4.0	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
1.3	2.7	GO:0072003	kidney rudiment formation(GO:0072003)
1.3	4.0	GO:0098972	dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
1.3	11.7	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
1.3	3.9	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.3	6.5	GO:0071306	cellular response to vitamin E(GO:0071306)
1.3	2.6	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
1.3	28.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
1.3	6.3	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
1.2	18.7	GO:0032482	Rab protein signal transduction(GO:0032482)
1.2	3.7	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
1.2	4.9	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
1.2	12.2	GO:0007220	Notch receptor processing(GO:0007220)
1.2	3.7	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
1.2	3.5	GO:0050955	thermoception(GO:0050955)
1.2	35.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
1.1	6.8	GO:0097039	protein linear polyubiquitination(GO:0097039)
1.1	4.6	GO:2000813	negative regulation of barbed-end actin filament capping(GO:2000813)
1.1	2.3	GO:0061197	fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
1.1	10.2	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.1	2.2	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
1.1	5.6	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
1.1	4.5	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.1	5.6	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.1	4.4	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
1.1	4.4	GO:0046462	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
1.1	12.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
1.1	9.7	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
1.1	27.0	GO:0036465	synaptic vesicle recycling(GO:0036465)
1.1	3.2	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
1.1	18.2	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
1.0	2.1	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
1.0	11.4	GO:0000338	protein deneddylation(GO:0000338)
1.0	12.5	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
1.0	8.3	GO:1900121	negative regulation of receptor binding(GO:1900121)
1.0	4.1	GO:0098886	modification of dendritic spine(GO:0098886)
1.0	3.1	GO:0036337	Fas signaling pathway(GO:0036337)
1.0	4.1	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
1.0	4.1	GO:1902856	negative regulation of nonmotile primary cilium assembly(GO:1902856)
1.0	3.0	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
1.0	28.3	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
1.0	7.1	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
1.0	10.1	GO:0070995	NADPH oxidation(GO:0070995)
1.0	26.9	GO:0019835	cytolysis(GO:0019835)
1.0	30.9	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
1.0	15.8	GO:0009629	response to gravity(GO:0009629)
1.0	5.9	GO:0000492	box C/D snoRNP assembly(GO:0000492)
1.0	15.7	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.0	2.0	GO:1904373	response to kainic acid(GO:1904373)
1.0	5.7	GO:0090383	phagosome acidification(GO:0090383)
1.0	3.8	GO:0021794	thalamus development(GO:0021794)
0.9	2.8	GO:1902103	metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.9	6.6	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.9	1.9	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.9	2.8	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.9	2.8	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
0.9	4.7	GO:0072069	DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.9	1.9	GO:0009182	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.9	2.8	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.9	7.4	GO:0099625	ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.9	4.5	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.9	8.0	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.9	0.9	GO:1904586	response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586)
0.9	2.6	GO:0090247	cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.9	3.4	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.8	7.6	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.8	2.5	GO:0007315	oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.8	1.7	GO:1900170	negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.8	2.5	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.8	2.5	GO:1903774	ubiquitin-dependent endocytosis(GO:0070086) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.8	4.1	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.8	15.6	GO:0008210	estrogen metabolic process(GO:0008210)
0.8	1.6	GO:0045869	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.8	1.6	GO:0043587	tongue morphogenesis(GO:0043587)
0.8	28.6	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.8	4.9	GO:0001554	luteolysis(GO:0001554)
0.8	7.3	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.8	0.8	GO:1902995	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.8	4.0	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.8	8.8	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.8	3.2	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.8	7.2	GO:0060068	vagina development(GO:0060068)
0.8	2.4	GO:0051977	lysophospholipid transport(GO:0051977)
0.8	6.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.8	5.5	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.8	3.1	GO:0051542	elastin biosynthetic process(GO:0051542)
0.8	3.9	GO:0003105	negative regulation of glomerular filtration(GO:0003105)
0.8	6.2	GO:2000303	regulation of ceramide biosynthetic process(GO:2000303)
0.8	17.7	GO:0051693	actin filament capping(GO:0051693)
0.8	5.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.8	1.5	GO:0048560	establishment of anatomical structure orientation(GO:0048560)
0.7	0.7	GO:0021898	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.7	2.9	GO:1901911	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.7	4.4	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.7	29.0	GO:0048599	oocyte development(GO:0048599)
0.7	1.4	GO:0035627	ceramide transport(GO:0035627)
0.7	7.7	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.7	5.6	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.7	10.5	GO:0021860	pyramidal neuron development(GO:0021860)
0.7	84.4	GO:0048167	regulation of synaptic plasticity(GO:0048167)
0.7	2.1	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.7	2.7	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.7	2.0	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.7	10.0	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.7	4.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.7	13.8	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.7	1.3	GO:1904948	midbrain dopaminergic neuron differentiation(GO:1904948)
0.7	2.6	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.7	1.3	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.6	1.9	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.6	5.2	GO:1904867	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.6	5.7	GO:0030575	nuclear body organization(GO:0030575)
0.6	1.3	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.6	8.9	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.6	1.3	GO:0015808	L-alanine transport(GO:0015808)
0.6	5.6	GO:0016926	protein desumoylation(GO:0016926)
0.6	2.5	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.6	18.1	GO:0008038	neuron recognition(GO:0008038)
0.6	1.2	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6	2.5	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.6	3.0	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.6	4.2	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.6	3.6	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.6	4.7	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.6	1.8	GO:0072344	rescue of stalled ribosome(GO:0072344)
0.6	8.2	GO:0036065	fucosylation(GO:0036065)
0.6	2.9	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.6	2.8	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.6	16.5	GO:0045761	regulation of adenylate cyclase activity(GO:0045761)
0.6	36.9	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.6	10.8	GO:0048240	sperm capacitation(GO:0048240)
0.6	11.3	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.6	11.3	GO:0045332	phospholipid translocation(GO:0045332)
0.6	10.1	GO:1900004	regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.6	0.6	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.6	6.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.6	2.2	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.6	4.4	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5	8.8	GO:0016578	histone deubiquitination(GO:0016578)
0.5	1.1	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.5	4.3	GO:0006527	arginine catabolic process(GO:0006527)
0.5	16.0	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5	1.6	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.5	3.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.5	9.9	GO:0050806	positive regulation of synaptic transmission(GO:0050806)
0.5	20.5	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.5	6.1	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.5	18.4	GO:0015914	phospholipid transport(GO:0015914)
0.5	2.0	GO:0090166	Golgi disassembly(GO:0090166)
0.5	1.5	GO:0042940	D-amino acid transport(GO:0042940)
0.5	2.5	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5	20.5	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.5	3.0	GO:0007512	adult heart development(GO:0007512)
0.5	4.9	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.5	3.4	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.5	14.2	GO:1901099	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.5	1.5	GO:0051697	protein delipidation(GO:0051697)
0.5	5.8	GO:0006108	malate metabolic process(GO:0006108)
0.5	6.2	GO:0022038	corpus callosum development(GO:0022038)
0.5	1.9	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.5	4.7	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.5	15.6	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.5	0.9	GO:0071321	cellular response to cGMP(GO:0071321)
0.5	10.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.5	2.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.5	4.2	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.5	3.2	GO:1901203	positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.5	1.8	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.5	3.2	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.5	2.7	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.4	8.4	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.4	8.3	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.4	5.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.4	6.8	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.4	8.9	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.4	6.3	GO:0006903	vesicle targeting(GO:0006903)
0.4	2.0	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4	3.2	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.4	6.4	GO:0045116	protein neddylation(GO:0045116)
0.4	3.2	GO:0001502	cartilage condensation(GO:0001502)
0.4	7.6	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.4	1.2	GO:0031223	auditory behavior(GO:0031223)
0.4	27.6	GO:0006836	neurotransmitter transport(GO:0006836)
0.4	5.4	GO:0015732	prostaglandin transport(GO:0015732)
0.4	1.9	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.4	6.9	GO:0051444	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.4	4.6	GO:0014850	response to muscle activity(GO:0014850)
0.4	0.4	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.4	2.2	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.4	0.7	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.4	1.4	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.4	1.4	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.3	3.8	GO:0030252	growth hormone secretion(GO:0030252)
0.3	6.7	GO:0097503	sialylation(GO:0097503)
0.3	0.9	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.3	0.9	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.3	1.5	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.3	3.9	GO:0000729	DNA double-strand break processing(GO:0000729)
0.3	3.5	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.3	0.3	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.3	4.7	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.3	0.9	GO:0006480	N-terminal protein amino acid methylation(GO:0006480) peptidyl-glycine modification(GO:0018201)
0.3	0.9	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.3	3.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.3	2.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.3	4.8	GO:0006098	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.3	1.1	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.3	3.4	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.3	1.1	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.3	1.9	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.3	0.8	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3	2.1	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3	0.5	GO:0036233	glycine import(GO:0036233)
0.3	4.2	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.3	3.9	GO:0031167	rRNA methylation(GO:0031167)
0.3	5.5	GO:0051293	establishment of spindle localization(GO:0051293)
0.3	3.6	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.3	2.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.3	4.6	GO:0006376	mRNA splice site selection(GO:0006376)
0.3	1.0	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.3	0.8	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
0.3	0.5	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.2	1.5	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.2	5.8	GO:0015701	bicarbonate transport(GO:0015701)
0.2	1.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.2	1.2	GO:0014807	regulation of somitogenesis(GO:0014807)
0.2	0.9	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.2	1.6	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.2	1.8	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2	1.6	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	1.8	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.2	2.9	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.2	3.1	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.2	3.5	GO:0051784	negative regulation of nuclear division(GO:0051784)
0.2	2.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.2	0.4	GO:1901069	guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099) guanosine-containing compound catabolic process(GO:1901069)
0.2	1.3	GO:0071910	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.2	21.5	GO:0097485	neuron projection guidance(GO:0097485)
0.2	2.5	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.2	4.6	GO:0044458	motile cilium assembly(GO:0044458)
0.2	12.1	GO:0035308	negative regulation of protein dephosphorylation(GO:0035308)
0.2	1.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2	0.6	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2	3.7	GO:0045687	positive regulation of glial cell differentiation(GO:0045687)
0.2	0.6	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	1.3	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.2	2.9	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.2	6.5	GO:0048747	muscle fiber development(GO:0048747)
0.2	1.9	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.2	4.1	GO:0014009	glial cell proliferation(GO:0014009)
0.2	2.0	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.2	5.0	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2	0.4	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2	0.9	GO:0051014	actin filament severing(GO:0051014)
0.2	3.6	GO:0051307	meiotic chromosome separation(GO:0051307)
0.2	3.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	7.2	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.2	0.7	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	2.3	GO:0016486	peptide hormone processing(GO:0016486)
0.2	2.2	GO:0021511	spinal cord patterning(GO:0021511)
0.2	3.2	GO:0097480	synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.2	0.8	GO:0015074	DNA integration(GO:0015074)
0.2	1.0	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.2	0.7	GO:0019046	viral latency(GO:0019042) release from viral latency(GO:0019046)
0.2	1.6	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2	1.0	GO:0032099	negative regulation of appetite(GO:0032099)
0.2	7.8	GO:0034502	protein localization to chromosome(GO:0034502)
0.2	0.8	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	4.4	GO:2001222	regulation of neuron migration(GO:2001222)
0.2	17.2	GO:0008360	regulation of cell shape(GO:0008360)
0.2	4.9	GO:0042073	intraciliary transport(GO:0042073)
0.2	0.3	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	4.4	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.2	2.1	GO:0002643	regulation of tolerance induction(GO:0002643)
0.1	1.5	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	1.2	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
0.1	4.5	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	0.6	GO:1901073	glucosamine-containing compound biosynthetic process(GO:1901073)
0.1	5.2	GO:0042446	hormone biosynthetic process(GO:0042446)
0.1	1.6	GO:0030204	chondroitin sulfate metabolic process(GO:0030204) chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1	4.3	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1	5.8	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.1	1.9	GO:0021696	cerebellar cortex morphogenesis(GO:0021696)
0.1	17.5	GO:0007018	microtubule-based movement(GO:0007018)
0.1	1.0	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.6	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.1	1.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.2	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	14.3	GO:0099536	synaptic signaling(GO:0099536)
0.1	2.8	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.1	4.8	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	4.5	GO:1902017	regulation of cilium assembly(GO:1902017)
0.1	0.5	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	1.6	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.1	1.2	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1	0.5	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.9	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.1	2.0	GO:0000266	mitochondrial fission(GO:0000266)
0.1	2.5	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
0.1	1.7	GO:0010573	vascular endothelial growth factor production(GO:0010573)
0.1	1.9	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	0.5	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.1	1.8	GO:0003009	skeletal muscle contraction(GO:0003009)
0.1	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.7	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.3	GO:0002076	osteoblast development(GO:0002076)
0.1	0.2	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.2	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.5	GO:0042749	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	1.0	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.8	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	0.7	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.7	GO:0007032	endosome organization(GO:0007032)
0.0	0.6	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.4	GO:0031297	replication fork processing(GO:0031297)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.0	0.2	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.0	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.5	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.2	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.8	16.8	GO:0099569	presynaptic cytoskeleton(GO:0099569)
15.8	47.3	GO:0098833	presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
13.6	40.8	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
12.8	38.3	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
12.2	12.2	GO:0044301	climbing fiber(GO:0044301)
9.7	97.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
9.7	29.0	GO:0032173	septin collar(GO:0032173)
8.7	26.0	GO:0090534	longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
8.5	25.6	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
7.5	45.0	GO:0033269	internode region of axon(GO:0033269)
6.4	19.3	GO:0000802	transverse filament(GO:0000802)
6.0	53.9	GO:0031209	SCAR complex(GO:0031209)
5.8	51.8	GO:0030314	junctional membrane complex(GO:0030314)
5.6	45.1	GO:0098831	presynaptic active zone cytoplasmic component(GO:0098831)
5.6	33.8	GO:0035189	Rb-E2F complex(GO:0035189)
5.6	16.7	GO:0005592	collagen type XI trimer(GO:0005592)
5.5	32.9	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
5.4	54.0	GO:0048787	presynaptic active zone membrane(GO:0048787)
5.3	21.3	GO:0045298	tubulin complex(GO:0045298)
5.0	124.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
4.9	217.6	GO:0048786	presynaptic active zone(GO:0048786)
4.5	18.1	GO:0044308	axonal spine(GO:0044308)
4.4	17.5	GO:0099524	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
4.1	12.3	GO:0098837	postsynaptic recycling endosome(GO:0098837)
3.9	23.5	GO:0032280	symmetric synapse(GO:0032280)
3.8	114.3	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
3.7	18.7	GO:0072534	perineuronal net(GO:0072534)
3.7	40.9	GO:0098839	postsynaptic density membrane(GO:0098839)
3.5	17.5	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
3.5	148.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
3.2	28.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
3.2	31.7	GO:0008091	spectrin(GO:0008091)
3.1	18.9	GO:0005955	calcineurin complex(GO:0005955)
3.1	108.4	GO:0032590	dendrite membrane(GO:0032590)
3.0	24.4	GO:0097418	neurofibrillary tangle(GO:0097418)
2.9	5.8	GO:0098888	extrinsic component of presynaptic membrane(GO:0098888)
2.9	8.6	GO:0005594	collagen type IX trimer(GO:0005594)
2.8	38.9	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
2.7	8.2	GO:1990923	PET complex(GO:1990923)
2.7	72.8	GO:0097440	apical dendrite(GO:0097440)
2.6	33.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
2.5	206.7	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
2.5	7.5	GO:0034774	secretory granule lumen(GO:0034774)
2.4	62.8	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
2.4	7.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
2.4	35.7	GO:0044224	juxtaparanode region of axon(GO:0044224)
2.4	2.4	GO:0000805	X chromosome(GO:0000805)
2.4	7.1	GO:0005962	mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
2.3	11.7	GO:0098984	neuron to neuron synapse(GO:0098984)
2.3	6.8	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
2.3	13.7	GO:0033010	paranodal junction(GO:0033010)
2.2	26.0	GO:0005859	muscle myosin complex(GO:0005859)
2.1	17.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
2.1	8.4	GO:1990005	granular vesicle(GO:1990005)
2.1	18.9	GO:0031045	dense core granule(GO:0031045)
2.0	6.1	GO:0043511	inhibin complex(GO:0043511)
2.0	41.5	GO:0005922	connexon complex(GO:0005922)
1.9	5.8	GO:0097444	spine apparatus(GO:0097444)
1.9	13.5	GO:0043203	axon hillock(GO:0043203)
1.9	14.9	GO:0097452	GAIT complex(GO:0097452)
1.9	5.6	GO:0060187	cell pole(GO:0060187)
1.8	39.9	GO:0032809	neuronal cell body membrane(GO:0032809)
1.8	10.6	GO:0002142	stereocilia ankle link complex(GO:0002142)
1.7	36.5	GO:0033268	node of Ranvier(GO:0033268)
1.7	27.0	GO:0097449	astrocyte projection(GO:0097449)
1.7	20.0	GO:0005796	Golgi lumen(GO:0005796)
1.7	15.0	GO:0043194	axon initial segment(GO:0043194)
1.7	11.6	GO:0070449	elongin complex(GO:0070449)
1.7	41.4	GO:0035327	transcriptionally active chromatin(GO:0035327)
1.7	14.9	GO:0000813	ESCRT I complex(GO:0000813)
1.6	80.8	GO:0043198	dendritic shaft(GO:0043198)
1.6	8.2	GO:0030015	CCR4-NOT core complex(GO:0030015)
1.6	8.2	GO:0070695	FHF complex(GO:0070695)
1.5	40.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.5	16.4	GO:0035253	ciliary rootlet(GO:0035253)
1.5	4.4	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
1.4	9.6	GO:0030877	beta-catenin destruction complex(GO:0030877)
1.4	4.1	GO:1990622	CHOP-ATF3 complex(GO:1990622)
1.4	6.8	GO:0071797	LUBAC complex(GO:0071797)
1.4	6.8	GO:0005879	axonemal microtubule(GO:0005879)
1.3	42.9	GO:0044295	axonal growth cone(GO:0044295)
1.3	3.9	GO:0031372	UBC13-MMS2 complex(GO:0031372)
1.3	95.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
1.3	7.5	GO:1990635	proximal dendrite(GO:1990635)
1.2	3.7	GO:0071942	XPC complex(GO:0071942)
1.2	31.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
1.2	290.0	GO:0098793	presynapse(GO:0098793)
1.1	16.0	GO:1902711	GABA-A receptor complex(GO:1902711)
1.1	5.6	GO:0097386	glial cell projection(GO:0097386)
1.1	11.2	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
1.1	4.5	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.1	14.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
1.1	3.3	GO:0032437	cuticular plate(GO:0032437)
1.1	4.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
1.1	21.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287)
1.1	19.4	GO:0031430	M band(GO:0031430)
1.0	6.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.0	13.5	GO:0030914	STAGA complex(GO:0030914)
1.0	12.1	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
1.0	4.0	GO:0005956	protein kinase CK2 complex(GO:0005956)
1.0	24.0	GO:0005865	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
1.0	2.9	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.9	2.8	GO:0070421	DNA ligase III-XRCC1 complex(GO:0070421)
0.9	0.9	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.9	2.7	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.9	3.6	GO:0097427	microtubule bundle(GO:0097427)
0.9	8.8	GO:0008290	F-actin capping protein complex(GO:0008290)
0.9	6.9	GO:0030137	COPI-coated vesicle(GO:0030137)
0.9	19.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.9	27.4	GO:0005721	pericentric heterochromatin(GO:0005721)
0.8	4.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.8	1.7	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.8	4.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.8	2.5	GO:0033186	CAF-1 complex(GO:0033186)
0.8	0.8	GO:1990909	Wnt signalosome(GO:1990909)
0.8	101.3	GO:0045211	postsynaptic membrane(GO:0045211)
0.8	25.5	GO:0016528	sarcoplasm(GO:0016528)
0.8	15.1	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.8	4.7	GO:0030478	actin cap(GO:0030478)
0.8	3.0	GO:0070545	PeBoW complex(GO:0070545)
0.8	5.3	GO:0001739	sex chromatin(GO:0001739)
0.7	8.9	GO:0097539	ciliary transition fiber(GO:0097539)
0.7	20.1	GO:0097228	sperm principal piece(GO:0097228)
0.7	11.4	GO:0070938	contractile ring(GO:0070938)
0.7	5.4	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7	10.2	GO:0071565	nBAF complex(GO:0071565)
0.7	6.1	GO:0061700	GATOR2 complex(GO:0061700)
0.7	60.0	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.7	4.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.7	43.5	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.6	1.9	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.6	15.4	GO:0002080	acrosomal membrane(GO:0002080)
0.6	21.6	GO:0008180	COP9 signalosome(GO:0008180)
0.6	5.0	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.6	4.3	GO:0031595	nuclear proteasome complex(GO:0031595)
0.6	6.8	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6	1.7	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.6	4.0	GO:0032839	dendrite cytoplasm(GO:0032839)
0.6	1.7	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.6	29.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.6	55.5	GO:0043204	perikaryon(GO:0043204)
0.5	1.6	GO:0044611	nuclear pore inner ring(GO:0044611)
0.5	4.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5	4.6	GO:0000439	core TFIIH complex(GO:0000439)
0.5	5.6	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.5	6.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5	4.0	GO:0016272	prefoldin complex(GO:0016272)
0.5	5.4	GO:0072546	ER membrane protein complex(GO:0072546)
0.5	4.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4	6.7	GO:0034709	methylosome(GO:0034709)
0.4	1.8	GO:0005827	polar microtubule(GO:0005827)
0.4	19.7	GO:0072686	mitotic spindle(GO:0072686)
0.4	2.1	GO:0036449	microtubule minus-end(GO:0036449)
0.4	3.2	GO:0045180	basal cortex(GO:0045180)
0.4	7.5	GO:0051233	spindle midzone(GO:0051233)
0.4	2.7	GO:0000124	SAGA complex(GO:0000124)
0.4	1.9	GO:0005828	kinetochore microtubule(GO:0005828)
0.4	5.1	GO:0001520	outer dense fiber(GO:0001520)
0.4	1.8	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.4	3.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.4	8.4	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.3	22.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.3	4.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3	20.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3	2.4	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.3	2.3	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.3	3.5	GO:0030127	COPII vesicle coat(GO:0030127)
0.3	2.5	GO:0071546	pi-body(GO:0071546)
0.3	24.8	GO:0031674	I band(GO:0031674)
0.3	1.6	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) oxoglutarate dehydrogenase complex(GO:0045252)
0.3	2.5	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.3	1.9	GO:0001740	Barr body(GO:0001740)
0.3	3.8	GO:0034704	calcium channel complex(GO:0034704)
0.3	8.1	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3	36.9	GO:0001650	fibrillar center(GO:0001650)
0.3	4.2	GO:0005838	proteasome regulatory particle(GO:0005838)
0.3	1.6	GO:0005869	dynactin complex(GO:0005869)
0.3	3.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.3	10.0	GO:0015030	Cajal body(GO:0015030)
0.3	3.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.3	12.6	GO:0036126	sperm flagellum(GO:0036126)
0.3	2.0	GO:0000815	ESCRT III complex(GO:0000815)
0.2	7.4	GO:0060170	ciliary membrane(GO:0060170)
0.2	31.4	GO:0005802	trans-Golgi network(GO:0005802)
0.2	22.2	GO:0031225	anchored component of membrane(GO:0031225)
0.2	1.7	GO:0060091	kinocilium(GO:0060091)
0.2	1.4	GO:0032444	activin responsive factor complex(GO:0032444)
0.2	2.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.2	1.5	GO:0031415	NatA complex(GO:0031415)
0.2	1.5	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2	3.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.2	0.6	GO:0071141	SMAD protein complex(GO:0071141)
0.2	1.6	GO:0030008	TRAPP complex(GO:0030008)
0.2	0.8	GO:0032021	NELF complex(GO:0032021)
0.2	3.8	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	5.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.2	3.8	GO:0043679	axon terminus(GO:0043679)
0.2	2.6	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2	0.7	GO:0002947	tumor necrosis factor receptor superfamily complex(GO:0002947)
0.2	6.6	GO:0001750	photoreceptor outer segment(GO:0001750)
0.2	13.7	GO:0030139	endocytic vesicle(GO:0030139)
0.2	5.9	GO:0048475	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.2	11.9	GO:0005875	microtubule associated complex(GO:0005875)
0.2	51.6	GO:0005813	centrosome(GO:0005813)
0.2	2.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	1.4	GO:0032300	mismatch repair complex(GO:0032300)
0.2	0.6	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2	7.9	GO:0005776	autophagosome(GO:0005776)
0.1	1.0	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	1.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	4.8	GO:0016592	mediator complex(GO:0016592)
0.1	3.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	2.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	2.3	GO:1990391	DNA repair complex(GO:1990391)
0.1	0.4	GO:0071817	MMXD complex(GO:0071817) CIA complex(GO:0097361)
0.1	1.2	GO:0031201	SNARE complex(GO:0031201)
0.1	7.7	GO:0005874	microtubule(GO:0005874)
0.1	8.5	GO:0045202	synapse(GO:0045202)
0.1	1.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	2.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	3.9	GO:0030426	growth cone(GO:0030426)
0.0	0.2	GO:0070461	SAGA-type complex(GO:0070461)
0.0	7.3	GO:0044297	cell body(GO:0044297)
0.0	0.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750)
0.0	0.4	GO:0030496	midbody(GO:0030496)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.8	117.6	GO:0097109	neuroligin family protein binding(GO:0097109)
11.7	35.0	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
11.4	45.8	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
9.6	38.3	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
9.3	46.7	GO:0004351	glutamate decarboxylase activity(GO:0004351)
7.5	22.6	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
7.2	50.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
6.8	20.5	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
6.6	92.4	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
6.5	32.4	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
6.3	25.1	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
5.8	23.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
5.7	28.7	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
5.6	16.9	GO:0086057	voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
5.6	16.8	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
5.5	27.5	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
5.5	32.9	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
5.5	16.4	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
5.3	26.7	GO:0008502	melatonin receptor activity(GO:0008502)
5.3	21.3	GO:0099609	microtubule lateral binding(GO:0099609)
5.0	25.1	GO:0004849	uridine kinase activity(GO:0004849)
5.0	25.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
4.9	43.9	GO:0032050	clathrin heavy chain binding(GO:0032050)
4.8	28.8	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
4.7	42.2	GO:0097100	supercoiled DNA binding(GO:0097100)
4.7	14.0	GO:0031997	N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
4.5	18.1	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
4.5	13.5	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
4.5	75.9	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
4.5	13.4	GO:0001847	opsonin receptor activity(GO:0001847)
4.4	30.6	GO:0005173	stem cell factor receptor binding(GO:0005173)
4.3	30.4	GO:0097001	ceramide binding(GO:0097001)
4.3	21.5	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
4.3	30.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
4.3	4.3	GO:0099510	calcium ion binding involved in regulation of cytosolic calcium ion concentration(GO:0099510)
4.2	8.4	GO:0015489	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
4.2	12.6	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
4.1	12.4	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
4.1	12.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
4.0	20.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
3.9	39.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
3.8	11.5	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.8	26.9	GO:0043426	MRF binding(GO:0043426)
3.7	14.9	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
3.7	14.9	GO:0033192	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
3.6	32.7	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
3.6	18.0	GO:0070052	collagen V binding(GO:0070052)
3.6	21.6	GO:0071532	ankyrin repeat binding(GO:0071532)
3.6	10.7	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
3.5	21.2	GO:0004985	opioid receptor activity(GO:0004985)
3.5	118.7	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
3.4	20.5	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
3.4	20.1	GO:0001515	opioid peptide activity(GO:0001515)
3.3	33.3	GO:0003680	AT DNA binding(GO:0003680)
3.2	9.7	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
3.2	35.5	GO:0019855	calcium channel inhibitor activity(GO:0019855)
3.2	12.9	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
3.2	9.6	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
3.1	37.0	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
3.0	21.2	GO:0097322	7SK snRNA binding(GO:0097322)
3.0	33.2	GO:0042577	lipid phosphatase activity(GO:0042577)
3.0	35.6	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.9	5.9	GO:0003987	acetate-CoA ligase activity(GO:0003987)
2.9	14.7	GO:0031849	olfactory receptor binding(GO:0031849)
2.9	14.7	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
2.9	11.7	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.9	8.6	GO:0031711	bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
2.9	17.1	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
2.9	11.4	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.8	19.8	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
2.8	16.8	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
2.8	8.3	GO:0009931	calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.7	13.3	GO:0034235	GPI anchor binding(GO:0034235)
2.6	7.9	GO:0008281	sulfonylurea receptor activity(GO:0008281)
2.6	15.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
2.6	15.6	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.6	10.3	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
2.5	10.1	GO:0004743	pyruvate kinase activity(GO:0004743)
2.5	36.9	GO:0008179	adenylate cyclase binding(GO:0008179)
2.5	7.4	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
2.4	68.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
2.4	7.2	GO:1902379	chemoattractant activity involved in axon guidance(GO:1902379)
2.4	9.5	GO:0019002	GMP binding(GO:0019002)
2.4	18.9	GO:0042043	neurexin family protein binding(GO:0042043)
2.3	11.7	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
2.3	13.8	GO:0004994	somatostatin receptor activity(GO:0004994)
2.3	11.4	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
2.3	6.8	GO:0004827	proline-tRNA ligase activity(GO:0004827) threonine-tRNA ligase activity(GO:0004829)
2.2	6.6	GO:0031708	endothelin B receptor binding(GO:0031708)
2.2	8.7	GO:0061665	SUMO ligase activity(GO:0061665)
2.2	6.5	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
2.2	10.9	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
2.2	17.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
2.2	8.6	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
2.1	8.5	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
2.1	10.6	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
2.1	20.9	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
2.1	20.9	GO:1903136	cuprous ion binding(GO:1903136)
2.0	8.2	GO:0034584	piRNA binding(GO:0034584)
2.0	6.1	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
2.0	12.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
2.0	19.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.0	31.4	GO:0005522	profilin binding(GO:0005522)
1.9	140.2	GO:0030276	clathrin binding(GO:0030276)
1.9	52.4	GO:0030506	ankyrin binding(GO:0030506)
1.9	9.6	GO:0005042	netrin receptor activity(GO:0005042)
1.9	27.8	GO:0035198	miRNA binding(GO:0035198)
1.9	270.9	GO:0044325	ion channel binding(GO:0044325)
1.8	9.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.8	28.4	GO:0005351	sugar:proton symporter activity(GO:0005351)
1.8	17.8	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
1.8	17.7	GO:0070016	armadillo repeat domain binding(GO:0070016)
1.8	7.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.8	7.0	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733)
1.7	5.2	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
1.7	19.2	GO:0004017	adenylate kinase activity(GO:0004017)
1.7	12.1	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
1.7	43.8	GO:0017075	syntaxin-1 binding(GO:0017075)
1.7	5.0	GO:0004807	triose-phosphate isomerase activity(GO:0004807)
1.6	11.5	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
1.6	31.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
1.6	4.9	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.6	4.8	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.6	95.4	GO:0005080	protein kinase C binding(GO:0005080)
1.6	37.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
1.5	23.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
1.5	44.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
1.4	8.7	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.4	4.3	GO:0035939	microsatellite binding(GO:0035939)
1.4	20.2	GO:0051378	serotonin binding(GO:0051378)
1.4	8.7	GO:0042289	MHC class II protein binding(GO:0042289)
1.4	4.3	GO:0016403	dimethylargininase activity(GO:0016403)
1.4	15.6	GO:0004708	MAP kinase kinase activity(GO:0004708)
1.4	4.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
1.4	4.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
1.4	5.5	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
1.4	12.2	GO:0009881	photoreceptor activity(GO:0009881)
1.3	26.8	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
1.3	19.9	GO:0031005	filamin binding(GO:0031005)
1.3	14.2	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.3	33.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.3	55.2	GO:0048365	Rac GTPase binding(GO:0048365)
1.3	1.3	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.2	6.2	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.2	6.1	GO:0004969	histamine receptor activity(GO:0004969)
1.2	3.6	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
1.2	78.1	GO:0019888	protein phosphatase regulator activity(GO:0019888)
1.1	3.4	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
1.1	9.9	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
1.1	14.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
1.1	4.3	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
1.1	21.5	GO:0032183	SUMO binding(GO:0032183)
1.1	12.8	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
1.1	6.3	GO:0004126	cytidine deaminase activity(GO:0004126)
1.0	10.4	GO:0048156	tau protein binding(GO:0048156)
1.0	9.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.0	10.2	GO:0015386	potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
1.0	5.0	GO:0043495	protein anchor(GO:0043495)
1.0	3.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
1.0	7.9	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
1.0	3.9	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
1.0	38.2	GO:0030295	protein kinase activator activity(GO:0030295)
1.0	8.8	GO:0008494	translation activator activity(GO:0008494)
1.0	11.7	GO:0015491	cation:cation antiporter activity(GO:0015491)
1.0	10.7	GO:0050321	tau-protein kinase activity(GO:0050321)
1.0	5.8	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.0	14.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.0	8.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.9	26.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.9	5.6	GO:0030955	potassium ion binding(GO:0030955)
0.9	1.8	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.9	2.6	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.9	1.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.8	9.2	GO:0016805	dipeptidase activity(GO:0016805)
0.8	15.1	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.8	72.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.8	3.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.8	11.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.8	4.8	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.8	21.0	GO:0001540	beta-amyloid binding(GO:0001540)
0.8	38.7	GO:0035254	glutamate receptor binding(GO:0035254)
0.8	2.3	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.8	4.6	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.8	4.6	GO:0032027	myosin light chain binding(GO:0032027)
0.8	4.6	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.8	2.3	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.7	5.9	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.7	2.9	GO:0051425	PTB domain binding(GO:0051425)
0.7	5.1	GO:1904047	S-adenosyl-L-methionine binding(GO:1904047)
0.7	2.9	GO:0000298	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.7	4.4	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.7	23.7	GO:0008536	Ran GTPase binding(GO:0008536)
0.7	19.0	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.7	14.0	GO:0017080	sodium channel regulator activity(GO:0017080)
0.7	14.3	GO:0031489	myosin V binding(GO:0031489)
0.7	16.0	GO:0004890	GABA-A receptor activity(GO:0004890)
0.7	17.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.6	12.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.6	4.4	GO:0008422	beta-glucosidase activity(GO:0008422)
0.6	1.9	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.6	5.6	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.6	2.5	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6	2.5	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.6	1.8	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.6	3.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.6	4.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.6	6.6	GO:0005523	tropomyosin binding(GO:0005523)
0.6	7.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.6	9.0	GO:0071889	14-3-3 protein binding(GO:0071889)
0.6	11.8	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.6	8.8	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.6	1.8	GO:0031208	POZ domain binding(GO:0031208)
0.6	18.6	GO:0030507	spectrin binding(GO:0030507)
0.6	14.9	GO:0004707	MAP kinase activity(GO:0004707)
0.6	3.4	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.6	7.2	GO:0003796	lysozyme activity(GO:0003796)
0.5	12.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.5	1.6	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.5	27.0	GO:0019003	GDP binding(GO:0019003)
0.5	4.8	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.5	1.6	GO:0008254	3'-nucleotidase activity(GO:0008254)
0.5	1.0	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.5	3.6	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5	4.0	GO:0050811	GABA receptor binding(GO:0050811)
0.5	35.9	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.5	1.4	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.5	11.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.5	2.8	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.5	7.0	GO:0043274	phospholipase binding(GO:0043274)
0.5	1.8	GO:0031014	troponin T binding(GO:0031014)
0.4	2.7	GO:0045545	syndecan binding(GO:0045545)
0.4	1.7	GO:0031628	opioid receptor binding(GO:0031628)
0.4	17.6	GO:0030544	Hsp70 protein binding(GO:0030544)
0.4	10.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.4	7.9	GO:0005112	Notch binding(GO:0005112)
0.4	9.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4	3.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.4	16.4	GO:0070330	aromatase activity(GO:0070330)
0.4	77.4	GO:0008017	microtubule binding(GO:0008017)
0.4	4.3	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4	3.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.4	11.8	GO:0019894	kinesin binding(GO:0019894)
0.4	5.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.4	1.9	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.4	4.9	GO:0005243	gap junction channel activity(GO:0005243)
0.4	11.0	GO:0030552	cAMP binding(GO:0030552)
0.4	3.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.4	4.0	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4	4.3	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.4	4.6	GO:0016918	retinal binding(GO:0016918) retinol binding(GO:0019841)
0.4	1.1	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.4	5.6	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.3	2.7	GO:1990459	transferrin receptor binding(GO:1990459)
0.3	4.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3	1.0	GO:0022843	voltage-gated cation channel activity(GO:0022843)
0.3	1.6	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3	21.1	GO:0005267	potassium channel activity(GO:0005267)
0.3	3.8	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.3	3.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.3	5.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.3	6.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.3	1.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.3	1.8	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.3	0.9	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
0.3	3.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.3	1.1	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.3	3.7	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3	4.9	GO:0070412	R-SMAD binding(GO:0070412)
0.3	1.5	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.3	9.9	GO:0015485	cholesterol binding(GO:0015485)
0.3	5.0	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2	1.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2	2.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.2	0.7	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2	32.6	GO:0005179	hormone activity(GO:0005179)
0.2	5.4	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.2	5.8	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.2	4.4	GO:0004622	lysophospholipase activity(GO:0004622)
0.2	6.5	GO:0005484	SNAP receptor activity(GO:0005484)
0.2	30.0	GO:0005096	GTPase activator activity(GO:0005096)
0.2	0.6	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.2	1.9	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	14.2	GO:0051082	unfolded protein binding(GO:0051082)
0.2	1.7	GO:0051400	BH domain binding(GO:0051400)
0.2	85.4	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.2	0.9	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.2	5.7	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.2	1.2	GO:0019209	kinase activator activity(GO:0019209)
0.2	1.6	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.2	3.9	GO:0017091	AU-rich element binding(GO:0017091)
0.2	1.3	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.2	6.1	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	42.2	GO:0005525	GTP binding(GO:0005525)
0.1	8.8	GO:0005518	collagen binding(GO:0005518)
0.1	5.8	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1	2.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	1.8	GO:0005123	death receptor binding(GO:0005123)
0.1	0.6	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.9	GO:0000339	RNA cap binding(GO:0000339)
0.1	8.8	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	0.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	2.5	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.1	1.8	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	10.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	4.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	22.3	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	1.1	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	0.5	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	1.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.2	GO:0034618	arginine binding(GO:0034618)
0.1	5.4	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.1	1.3	GO:0017022	myosin binding(GO:0017022)
0.1	1.9	GO:0005109	frizzled binding(GO:0005109)
0.1	0.5	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.1	0.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	1.0	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.3	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.0	0.2	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.2	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.3	10.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
4.0	102.9	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
3.0	36.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
2.6	70.9	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
2.5	43.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
2.4	81.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
2.3	107.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.4	6.8	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
1.3	34.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
1.1	9.2	PID S1P S1P4 PATHWAY	S1P4 pathway
1.0	37.0	PID RAS PATHWAY	Regulation of Ras family activation
1.0	26.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
1.0	8.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.9	20.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.9	38.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.9	40.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.9	9.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.7	2.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.6	12.9	PID RAC1 PATHWAY	RAC1 signaling pathway
0.5	4.9	ST GAQ PATHWAY	G alpha q Pathway
0.5	8.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.5	6.4	PID REELIN PATHWAY	Reelin signaling pathway
0.5	26.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.5	4.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.4	5.8	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.4	11.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.4	8.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.4	12.6	PID ATR PATHWAY	ATR signaling pathway
0.4	14.9	PID ATM PATHWAY	ATM pathway
0.4	15.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3	8.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.3	14.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.3	3.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.3	7.0	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	11.6	PID PLK1 PATHWAY	PLK1 signaling events
0.3	1.9	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	5.5	PID ARF 3PATHWAY	Arf1 pathway
0.2	1.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	3.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	7.4	PID CDC42 PATHWAY	CDC42 signaling events
0.1	1.4	PID BARD1 PATHWAY	BARD1 signaling events
0.1	0.5	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	1.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	4.2	PID BMP PATHWAY	BMP receptor signaling
0.1	31.5	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	0.5	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	1.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	2.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	1.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.1	50.5	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
8.6	17.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
5.0	70.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
4.0	72.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
3.7	66.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
3.3	73.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
3.1	49.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
2.9	34.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
2.7	41.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
2.7	43.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
2.6	132.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
2.4	4.8	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
2.3	41.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
2.3	34.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
2.2	51.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
2.2	13.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
2.2	37.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
2.1	16.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
2.1	37.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.8	57.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.7	39.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
1.7	20.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
1.6	49.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
1.6	9.7	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
1.6	9.7	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
1.5	36.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
1.4	20.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
1.4	59.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
1.4	21.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.4	28.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
1.3	20.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.3	29.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
1.3	35.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.2	47.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
1.2	6.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.2	20.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
1.2	9.3	REACTOME OPSINS	Genes involved in Opsins
1.1	34.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
1.1	5.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.1	4.3	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
1.0	26.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.0	16.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.0	17.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
1.0	25.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
1.0	18.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.9	7.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.9	10.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.8	10.8	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.8	12.8	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.7	10.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.7	5.9	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.7	11.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.7	17.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.7	8.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.7	59.5	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.7	5.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.7	11.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.6	26.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6	5.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.6	11.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.6	2.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.6	6.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.6	5.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.6	24.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6	4.0	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.6	42.1	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.6	3.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.5	9.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.5	20.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.5	8.6	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.5	7.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.5	10.8	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.4	10.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.4	6.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.4	7.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	39.3	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.4	4.8	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.4	52.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.4	2.6	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.4	4.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.3	18.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.3	6.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3	15.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3	8.5	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.3	7.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.3	5.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.3	7.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	5.7	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2	3.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.2	6.7	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.2	4.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	9.6	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.2	1.3	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	2.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	3.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	1.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	9.0	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2	4.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	3.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.2	4.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	1.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	2.0	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1	9.0	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	0.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	1.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.2	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	2.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.8	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.4	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type

Results for Klf6_Patz1

Z-value: 1.62

Motif logo

Transcription factors associated with Klf6_Patz1

Activity-expression correlation:

Activity profile of Klf6_Patz1 motif

Sorted Z-values of Klf6_Patz1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf6_Patz1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: