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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Klf7

Z-value: 0.56

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Transcription factors associated with Klf7

Gene Symbol Gene ID Gene Info
Klf7
ENSRNOG00000046242 Kruppel like factor 7
Klf7
ENSRNOG00000012961 Kruppel like factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf7rn6_v1_chr9_-_70787913_707879130.072.3e-01Click!

Activity profile of Klf7 motif

Sorted Z-values of Klf7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_56962161 12.23 ENSRNOT00000026038
Alox15
arachidonate 15-lipoxygenase
chr9_-_82419288 10.16 ENSRNOT00000004797
Tuba4a
tubulin, alpha 4A
chr7_-_138039630 9.97 ENSRNOT00000008138
Slc38a1
solute carrier family 38, member 1
chr9_-_69953182 8.98 ENSRNOT00000015852
Ndufs1
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr1_-_56683731 8.92 ENSRNOT00000014552
Thbs2
thrombospondin 2
chr7_-_138039984 8.78 ENSRNOT00000089806
Slc38a1
solute carrier family 38, member 1
chr15_-_28313841 8.26 ENSRNOT00000085897
Ndrg2
NDRG family member 2
chr9_-_38196273 6.40 ENSRNOT00000044452
Dst
dystonin
chr16_-_81028656 5.82 ENSRNOT00000091296
Dcun1d2
defective in cullin neddylation 1 domain containing 2
chr4_-_120817377 5.70 ENSRNOT00000021826
Podxl2
podocalyxin-like 2
chr10_+_58613674 5.48 ENSRNOT00000010975
Fam64a
family with sequence similarity 64, member A
chr20_+_3422461 4.98 ENSRNOT00000084917
ENSRNOT00000079854
Tubb5
tubulin, beta 5 class I
chr1_-_188190778 4.81 ENSRNOT00000092657
ENSRNOT00000022988
Coq7
coenzyme Q7, hydroxylase
chr2_+_113984824 4.23 ENSRNOT00000086399
Tnik
TRAF2 and NCK interacting kinase
chr7_-_134722215 4.22 ENSRNOT00000036750
Prickle1
prickle planar cell polarity protein 1
chr16_-_74408030 4.22 ENSRNOT00000026418
Slc20a2
solute carrier family 20 member 2
chr8_-_77992621 4.10 ENSRNOT00000085843
Myzap
myocardial zonula adherens protein
chr1_+_56242346 4.07 ENSRNOT00000019317
Smoc2
SPARC related modular calcium binding 2
chr10_-_25890639 3.98 ENSRNOT00000085499
Hmmr
hyaluronan-mediated motility receptor
chr9_+_23420654 3.84 ENSRNOT00000073595
LOC688459
hypothetical protein LOC688459
chr2_+_113984646 3.72 ENSRNOT00000016799
Tnik
TRAF2 and NCK interacting kinase
chr10_+_59173268 3.65 ENSRNOT00000013486
Ube2g1
ubiquitin-conjugating enzyme E2G 1
chr7_-_140640953 3.57 ENSRNOT00000083156
Tuba1a
tubulin, alpha 1A
chr1_+_213991620 3.56 ENSRNOT00000038691
Rplp2
ribosomal protein lateral stalk subunit P2
chr16_+_36116258 3.53 ENSRNOT00000017652
Sap30
Sin3A associated protein 30
chr13_-_87847263 3.49 ENSRNOT00000003650
Nuf2
NUF2, NDC80 kinetochore complex component
chr1_+_220400855 3.38 ENSRNOT00000027178
Slc29a2
solute carrier family 29 member 2
chr12_-_38274036 3.30 ENSRNOT00000063990
Kntc1
kinetochore associated 1
chr3_+_112428395 3.25 ENSRNOT00000079109
ENSRNOT00000048141
Stard9
StAR-related lipid transfer domain containing 9
chr4_+_167219728 3.00 ENSRNOT00000075273
Smim10l1
small integral membrane protein 10 like 1
chr1_+_220307394 2.87 ENSRNOT00000071891
LOC108348052
equilibrative nucleoside transporter 2
chr8_+_72029489 2.82 ENSRNOT00000089336
Herc1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr7_+_140758615 2.69 ENSRNOT00000089448
Troap
trophinin associated protein
chr16_+_74408183 2.65 ENSRNOT00000036506
Smim19
small integral membrane protein 19
chr10_+_86819929 2.56 ENSRNOT00000038228
Cdc6
cell division cycle 6
chr11_+_44877859 2.54 ENSRNOT00000060838
Col8a1
collagen type VIII alpha 1 chain
chr7_-_145450233 2.54 ENSRNOT00000092974
ENSRNOT00000021523
Calcoco1
calcium binding and coiled coil domain 1
chr16_-_47207487 2.53 ENSRNOT00000059459
Dctd
dCMP deaminase
chr10_-_13619935 2.45 ENSRNOT00000064392
Ccnf
cyclin F
chr19_+_52647070 2.43 ENSRNOT00000068389
ENSRNOT00000087857
Crispld2
cysteine-rich secretory protein LCCL domain containing 2
chr3_-_79743737 2.42 ENSRNOT00000013584
Ptpmt1
protein tyrosine phosphatase, mitochondrial 1
chr7_-_144322240 2.35 ENSRNOT00000089290
LOC100912282
calcium-binding and coiled-coil domain-containing protein 1-like
chr10_-_49192693 2.31 ENSRNOT00000004294
Zfp286a
zinc finger protein 286A
chr8_+_122003916 2.23 ENSRNOT00000091980
Clasp2
cytoplasmic linker associated protein 2
chr7_-_130176696 2.23 ENSRNOT00000051347
Dennd6b
DENN domain containing 6B
chr9_-_61033553 2.18 ENSRNOT00000002864
ENSRNOT00000082681
Gtf3c3
general transcription factor IIIC subunit 3
chr7_+_144865608 2.18 ENSRNOT00000091596
ENSRNOT00000055285
Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
chr12_-_39185168 2.03 ENSRNOT00000001799
Rnf34
ring finger protein 34
chr1_-_60332899 2.03 ENSRNOT00000078636
LOC108348087
vomeronasal type-1 receptor 4-like
chr1_+_214428526 2.00 ENSRNOT00000057030
LOC100911575
60S acidic ribosomal protein P2-like
chr10_+_86819472 1.97 ENSRNOT00000081424
Cdc6
cell division cycle 6
chr10_-_15211325 1.86 ENSRNOT00000027083
Rhot2
ras homolog family member T2
chr1_+_196095214 1.84 ENSRNOT00000080741
LOC691716
similar to ribosomal protein S15a
chr1_-_228263198 1.83 ENSRNOT00000028572
Olr1874
olfactory receptor 1874
chr9_+_69953440 1.82 ENSRNOT00000034740
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr10_+_57260680 1.81 ENSRNOT00000035445
Gp1ba
glycoprotein Ib platelet alpha subunit
chr12_+_22026075 1.81 ENSRNOT00000029041
LOC100910838
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1-like
chr9_+_64095978 1.73 ENSRNOT00000021533
Maip1
matrix AAA peptidase interacting protein 1
chr2_-_189899325 1.71 ENSRNOT00000017561
Chtop
chromatin target of PRMT1
chr11_-_67618704 1.70 ENSRNOT00000042208
Ccdc58
coiled-coil domain containing 58
chr8_-_116856548 1.67 ENSRNOT00000043825
Rnf123
ring finger protein 123
chr13_-_78521911 1.63 ENSRNOT00000087506
Rabgap1l
RAB GTPase activating protein 1-like
chr10_-_38985466 1.62 ENSRNOT00000010121
Il13
interleukin 13
chr5_+_48561339 1.59 ENSRNOT00000010614
ENSRNOT00000091827
Rngtt
RNA guanylyltransferase and 5'-phosphatase
chr19_+_14392423 1.53 ENSRNOT00000018880
Tom1
target of myb1 membrane trafficking protein
chr3_-_104018861 1.53 ENSRNOT00000008387
Chrm5
cholinergic receptor, muscarinic 5
chr8_+_128806129 1.52 ENSRNOT00000025225
Rpsa
ribosomal protein SA
chrX_+_120859968 1.47 ENSRNOT00000085185
Wdr44
WD repeat domain 44
chr9_-_65329066 1.44 ENSRNOT00000018284
Ppil3
peptidylprolyl isomerase like 3
chr10_-_25847994 1.40 ENSRNOT00000082076
Mat2b
methionine adenosyltransferase 2B
chr10_+_103956019 1.38 ENSRNOT00000045875
Mrpl58
mitochondrial ribosomal protein L58
chr9_+_90880614 1.37 ENSRNOT00000077859
ENSRNOT00000020705
ENSRNOT00000089142
Mff
mitochondrial fission factor
chr8_+_4019722 1.36 ENSRNOT00000073415
Vom2r23
vomeronasal 2 receptor, 23
chrX_+_120860178 1.36 ENSRNOT00000088661
Wdr44
WD repeat domain 44
chr17_-_71897972 1.32 ENSRNOT00000065942
Sfmbt2
Scm-like with four mbt domains 2
chr1_+_86948918 1.32 ENSRNOT00000084839
Sirt2
sirtuin 2
chr4_+_173115125 1.30 ENSRNOT00000074673
LOC100910575
serine-threonine kinase receptor-associated protein-like
chr3_-_165039707 1.21 ENSRNOT00000081648
Kcng1
potassium voltage-gated channel modifier subfamily G member 1
chr1_+_178039063 1.20 ENSRNOT00000046313
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr9_-_64096265 1.15 ENSRNOT00000013502
Tyw5
tRNA-yW synthesizing protein 5
chr8_+_42260375 1.12 ENSRNOT00000074713
LOC100912245
olfactory receptor 143-like
chr10_-_15161938 1.11 ENSRNOT00000026641
Fam173a
family with sequence similarity 173, member A
chr4_-_150616895 1.09 ENSRNOT00000073562
Ankrd26
ankyrin repeat domain 26
chr10_-_65805693 1.08 ENSRNOT00000012245
Tnfaip1
TNF alpha induced protein 1
chr4_-_182844291 1.07 ENSRNOT00000064320
Tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr18_+_55505993 1.07 ENSRNOT00000043736
RGD1309362
similar to interferon-inducible GTPase
chr6_-_7741414 1.05 ENSRNOT00000038246
Thada
THADA, armadillo repeat containing
chr1_+_60117804 1.04 ENSRNOT00000080437
Vom1r8
vomeronasal 1 receptor 8
chr1_-_52992213 1.04 ENSRNOT00000033528
Prr18
proline rich 18
chr8_-_114449956 1.01 ENSRNOT00000056414
Col6a6
collagen type VI alpha 6 chain
chr17_-_18028808 0.98 ENSRNOT00000022244
Kdm1b
lysine demethylase 1B
chr5_+_107233230 0.95 ENSRNOT00000029976
Ifne
interferon, epsilon
chr19_-_29802083 0.94 ENSRNOT00000024755
AC123471.1

chr12_+_38274297 0.94 ENSRNOT00000087905
ENSRNOT00000057788
Rsrc2
arginine and serine rich coiled-coil 2
chr1_+_168378637 0.91 ENSRNOT00000028936
Olr86
olfactory receptor 86
chr2_+_150211898 0.90 ENSRNOT00000018767
Sucnr1
succinate receptor 1
chr14_+_100415668 0.89 ENSRNOT00000008057
C1d
C1D nuclear receptor co-repressor
chr1_-_100810522 0.89 ENSRNOT00000027260
Atf5
activating transcription factor 5
chr2_-_35435719 0.88 ENSRNOT00000087827
LOC100910041
olfactory receptor 146-like
chr14_-_34218961 0.86 ENSRNOT00000072588
LOC686911
similar to Exocyst complex component 1 (Exocyst complex component Sec3)
chr15_-_36213666 0.85 ENSRNOT00000078704
Olr1291
olfactory receptor 1291
chr8_-_43007390 0.83 ENSRNOT00000072355
LOC100910445
olfactory receptor 146-like
chr15_+_28377996 0.77 ENSRNOT00000078475
Arhgef40
Rho guanine nucleotide exchange factor 40
chr8_+_49544858 0.75 ENSRNOT00000075133
LOC102546809
uncharacterized LOC102546809
chr9_-_23352668 0.75 ENSRNOT00000075279
Mut
methylmalonyl CoA mutase
chr4_+_7835949 0.75 ENSRNOT00000065962
Tomm7
translocase of outer mitochondrial membrane 7
chr18_+_55391388 0.75 ENSRNOT00000071612
LOC100910934
interferon-inducible GTPase 1-like
chr11_-_81379640 0.68 ENSRNOT00000002484
Eif4a2
eukaryotic translation initiation factor 4A2
chr18_+_59748444 0.66 ENSRNOT00000024752
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr17_-_62462644 0.63 ENSRNOT00000024545
Ccny
cyclin Y
chr19_-_28296640 0.62 ENSRNOT00000041115
ENSRNOT00000042781
AABR07043429.1

chr1_+_85470831 0.61 ENSRNOT00000057096
Timm50
translocase of inner mitochondrial membrane 50
chr4_-_28310178 0.58 ENSRNOT00000084021
RGD1563091
similar to OEF2
chr11_-_81379871 0.57 ENSRNOT00000089294
Eif4a2
eukaryotic translation initiation factor 4A2
chr1_-_226630900 0.49 ENSRNOT00000028092
Tmem138
transmembrane protein 138
chr2_-_35485401 0.49 ENSRNOT00000072751
AABR07007931.1

chr9_-_69878706 0.46 ENSRNOT00000035879
Ino80d
INO80 complex subunit D
chr10_+_44804631 0.45 ENSRNOT00000040720
Olr1460
olfactory receptor 1460
chr10_-_89225297 0.45 ENSRNOT00000027868
ENSRNOT00000082010
Becn1
beclin 1
chr1_-_22508170 0.33 ENSRNOT00000050763
Taar7c
trace amine-associated receptor 7C
chr12_-_17972737 0.21 ENSRNOT00000001783
Fam20c
FAM20C, golgi associated secretory pathway kinase
chr2_+_12102487 0.18 ENSRNOT00000089209
ENSRNOT00000072155
LOC100912538
centrin-3-like
chr3_+_150055749 0.12 ENSRNOT00000055335
Actl10
actin-like 10
chr5_+_126254142 0.10 ENSRNOT00000057471
Pars2
prolyl-tRNA synthetase 2, mitochondrial (putative)

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 18.8 GO:0006868 glutamine transport(GO:0006868)
2.4 12.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.1 8.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.6 4.8 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
1.1 3.4 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.7 3.6 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
0.6 4.5 GO:1904117 cellular response to vasopressin(GO:1904117)
0.6 1.7 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
0.6 8.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.5 2.2 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.5 1.6 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.5 1.6 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.5 2.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.5 1.5 GO:0006407 rRNA export from nucleus(GO:0006407)
0.5 4.2 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.4 1.3 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.4 2.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.4 6.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 2.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 1.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.3 1.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 2.9 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.3 5.8 GO:0045116 protein neddylation(GO:0045116)
0.2 1.2 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.2 2.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.7 GO:1990743 protein sialylation(GO:1990743)
0.2 5.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 1.7 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.2 0.5 GO:0032258 CVT pathway(GO:0032258)
0.1 9.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 2.8 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.7 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 4.2 GO:0006817 phosphate ion transport(GO:0006817)
0.1 8.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 2.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.2 GO:0097187 dentinogenesis(GO:0097187)
0.1 1.9 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 3.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.0 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 8.2 GO:0051225 spindle assembly(GO:0051225)
0.1 1.8 GO:0042730 fibrinolysis(GO:0042730)
0.1 1.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.4 GO:0006415 translational termination(GO:0006415)
0.1 0.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 1.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.9 GO:0021930 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1 2.5 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)
0.1 0.9 GO:0051601 exocyst localization(GO:0051601)
0.1 3.8 GO:0006414 translational elongation(GO:0006414)
0.1 1.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.5 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 3.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.8 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 1.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 4.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.1 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.9 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 1.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.5 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 2.3 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 1.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.6 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 1.6 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 7.5 GO:0007017 microtubule-based process(GO:0007017)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.1 3.3 GO:1990423 RZZ complex(GO:1990423)
0.7 2.2 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
0.7 3.5 GO:0031262 Ndc80 complex(GO:0031262)
0.6 1.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 4.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5 5.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 8.9 GO:0031091 platelet alpha granule(GO:0031091)
0.3 2.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 2.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 4.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 9.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.3 GO:0033010 paranodal junction(GO:0033010)
0.2 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 10.9 GO:0005811 lipid particle(GO:0005811)
0.1 4.5 GO:0051233 spindle midzone(GO:0051233)
0.1 1.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.7 GO:0000346 transcription export complex(GO:0000346)
0.1 2.6 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 3.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.2 GO:0033391 chromatoid body(GO:0033391)
0.1 3.2 GO:0005871 kinesin complex(GO:0005871)
0.1 4.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 8.3 GO:0030426 growth cone(GO:0030426)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 13.0 GO:0005874 microtubule(GO:0005874)
0.0 1.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 3.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 15.8 GO:0030424 axon(GO:0030424)
0.0 6.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.2 GO:0055037 recycling endosome(GO:0055037)
0.0 1.1 GO:0005884 actin filament(GO:0005884)
0.0 0.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.9 GO:0005769 early endosome(GO:0005769)
0.0 3.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.8 GO:0005840 ribosome(GO:0005840)
0.0 1.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
3.1 12.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.8 4.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.5 2.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.5 1.6 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.4 1.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.4 8.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 9.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 1.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 5.8 GO:0097602 cullin family protein binding(GO:0097602)
0.3 2.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.3 1.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 2.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.3 2.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 5.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 3.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 1.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 4.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 13.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.5 GO:0019239 deaminase activity(GO:0019239)
0.1 0.7 GO:0015266 protein channel activity(GO:0015266)
0.1 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 10.9 GO:0008201 heparin binding(GO:0008201)
0.1 8.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 3.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 3.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 7.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 2.0 GO:0002039 p53 binding(GO:0002039)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 6.0 GO:0005549 odorant binding(GO:0005549)
0.0 1.6 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 8.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 12.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 8.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 4.5 PID ATR PATHWAY ATR signaling pathway
0.1 6.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 8.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 3.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 12.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 4.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 1.2 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 9.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 3.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 8.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 1.6 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 4.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 5.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 5.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME TRANSLATION Genes involved in Translation
0.0 2.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing