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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Meis1

Z-value: 1.18

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Transcription factors associated with Meis1

Gene Symbol Gene ID Gene Info
Meis1
ENSRNOG00000004606 Meis homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meis1rn6_v1_chr14_-_103321270_103321270-0.196.6e-04Click!

Activity profile of Meis1 motif

Sorted Z-values of Meis1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_80862963 67.58 ENSRNOT00000004864
Fmo3
flavin containing monooxygenase 3
chr20_-_45024315 60.71 ENSRNOT00000066856
RGD1304770
similar to Na+ dependent glucose transporter 1
chr9_+_4817854 47.08 ENSRNOT00000040879
LOC100910526
sulfotransferase 1C2-like
chr8_-_49109981 46.51 ENSRNOT00000019933
Ttc36
tetratricopeptide repeat domain 36
chr5_+_33784715 42.81 ENSRNOT00000035685
Slc7a13
solute carrier family 7 member 13
chr19_+_15094309 42.12 ENSRNOT00000083500
Ces1f
carboxylesterase 1F
chr9_+_4094995 41.77 ENSRNOT00000089450
LOC100910057
sulfotransferase 1C2-like
chrX_-_1848904 34.79 ENSRNOT00000010984
Rgn
regucalcin
chr14_+_22517774 32.71 ENSRNOT00000047655
Ugt2b37
UDP-glucuronosyltransferase 2 family, member 37
chr8_+_115150514 32.06 ENSRNOT00000016504
Abhd14b
abhydrolase domain containing 14b
chr5_+_133896141 32.04 ENSRNOT00000011434
Pdzk1ip1
PDZK1 interacting protein 1
chr17_+_76306585 31.53 ENSRNOT00000065978
Dhtkd1
dehydrogenase E1 and transketolase domain containing 1
chr18_-_15089988 29.73 ENSRNOT00000074116
Mep1b
meprin A subunit beta
chr5_-_159962218 27.37 ENSRNOT00000050729
Clcnkb
chloride voltage-gated channel Kb
chr3_-_46726946 27.07 ENSRNOT00000011030
ENSRNOT00000086576
Itgb6
integrin subunit beta 6
chr7_-_68512397 26.91 ENSRNOT00000058036
Slc16a7
solute carrier family 16 member 7
chr2_+_68820615 26.86 ENSRNOT00000087007
ENSRNOT00000089504
Egf
epidermal growth factor
chr8_+_85355766 25.25 ENSRNOT00000010583
Gcm1
glial cells missing homolog 1
chr1_+_153589471 24.76 ENSRNOT00000023205
Fzd4
frizzled class receptor 4
chr9_+_4107246 24.48 ENSRNOT00000078212
AABR07066160.1

chr16_+_18690649 24.01 ENSRNOT00000015190
Mat1a
methionine adenosyltransferase 1A
chr10_-_47997097 24.00 ENSRNOT00000032092
Slc5a10
solute carrier family 5 member 10
chr18_+_69841053 23.79 ENSRNOT00000071545
ENSRNOT00000030613
ENSRNOT00000075543
Mro
maestro
chr1_+_100164400 22.63 ENSRNOT00000080334
LOC108348116
glandular kallikrein-3, submandibular-like
chr13_+_55274199 21.76 ENSRNOT00000029679
Atp6v1g3
ATPase H+ transporting V1 subunit G3
chr8_-_53816447 21.34 ENSRNOT00000011454
Ttc12
tetratricopeptide repeat domain 12
chr9_-_4327679 21.32 ENSRNOT00000073468
LOC100910235
sulfotransferase 1C1-like
chr9_+_95285592 20.65 ENSRNOT00000063853
Ugt1a5
UDP glucuronosyltransferase family 1 member A5
chr3_-_2453415 20.63 ENSRNOT00000079773
Slc34a3
solute carrier family 34 member 3
chr11_-_77703255 20.25 ENSRNOT00000083319
Cldn16
claudin 16
chr8_+_80965255 20.16 ENSRNOT00000079508
Wdr72
WD repeat domain 72
chr19_+_39357791 20.02 ENSRNOT00000086435
ENSRNOT00000015006
Cyb5b
cytochrome b5 type B
chr12_-_41625403 19.88 ENSRNOT00000001876
Sds
serine dehydratase
chr2_-_117454769 19.22 ENSRNOT00000068381
Mecom
MDS1 and EVI1 complex locus
chr20_-_27117663 19.11 ENSRNOT00000000434
Pbld1
phenazine biosynthesis-like protein domain containing 1
chr14_-_44613904 18.80 ENSRNOT00000003811
Klb
klotho beta
chr3_-_51297852 18.39 ENSRNOT00000001607
Cobll1
cordon-bleu WH2 repeat protein-like 1
chr10_-_59883839 17.75 ENSRNOT00000093579
Aspa
aspartoacylase
chr11_-_32508420 16.45 ENSRNOT00000002717
Kcne1
potassium voltage-gated channel subfamily E regulatory subunit 1
chr8_+_49713190 16.11 ENSRNOT00000022074
Fxyd2
FXYD domain-containing ion transport regulator 2
chr2_+_128461224 16.04 ENSRNOT00000018872
Jade1
jade family PHD finger 1
chr19_+_55982740 15.83 ENSRNOT00000021397
Dpep1
dipeptidase 1 (renal)
chr1_-_216663720 15.03 ENSRNOT00000078944
ENSRNOT00000077409
Cdkn1c
cyclin-dependent kinase inhibitor 1C
chr10_-_18506337 14.85 ENSRNOT00000043036
Gabrp
gamma-aminobutyric acid type A receptor pi subunit
chr19_+_60017746 14.48 ENSRNOT00000042623
Pard3
par-3 family cell polarity regulator
chr5_+_137371825 14.01 ENSRNOT00000072816
Tmem125
transmembrane protein 125
chr4_+_22084954 13.94 ENSRNOT00000090968
Crot
carnitine O-octanoyltransferase
chr15_-_8989580 13.85 ENSRNOT00000061402
Thrb
thyroid hormone receptor beta
chr2_-_94315976 13.84 ENSRNOT00000071039
AABR07009357.1

chr4_-_117607428 13.25 ENSRNOT00000021243
LOC103690139
probable N-acetyltransferase CML6
chr1_+_14224393 13.05 ENSRNOT00000016037
Perp
PERP, TP53 apoptosis effector
chr7_+_101146820 12.58 ENSRNOT00000080206
AABR07058124.3

chr1_+_15180328 12.51 ENSRNOT00000050656
Il20ra
interleukin 20 receptor subunit alpha
chr1_-_213907144 12.48 ENSRNOT00000054874
Sigirr
single Ig and TIR domain containing
chr13_-_37287458 11.99 ENSRNOT00000003391
Insig2
insulin induced gene 2
chr5_-_57429245 11.63 ENSRNOT00000013803
Aqp3
aquaporin 3
chr4_+_101180404 11.45 ENSRNOT00000007624
Suclg1
succinate-CoA ligase, alpha subunit
chr4_+_99063181 10.98 ENSRNOT00000008840
Fabp1
fatty acid binding protein 1
chr4_-_23119005 10.89 ENSRNOT00000048061
Steap4
STEAP4 metalloreductase
chr1_+_141218095 10.82 ENSRNOT00000051411
LOC691427
similar to 6.8 kDa mitochondrial proteolipid
chr7_-_75364166 10.65 ENSRNOT00000036852
Snx31
sorting nexin 31
chr3_-_136936650 10.62 ENSRNOT00000036273
ENSRNOT00000083061
Kif16b
kinesin family member 16B
chr9_-_23352668 10.46 ENSRNOT00000075279
Mut
methylmalonyl CoA mutase
chr14_-_8600512 10.35 ENSRNOT00000092537
Arhgap24
Rho GTPase activating protein 24
chr2_+_220432037 10.30 ENSRNOT00000021988
Frrs1
ferric-chelate reductase 1
chr3_-_105214989 10.16 ENSRNOT00000037895
Grem1
gremlin 1, DAN family BMP antagonist
chr1_+_81372650 10.14 ENSRNOT00000088829
Zfp428
zinc finger protein 428
chrX_+_34623405 10.11 ENSRNOT00000041924
Nhs
NHS actin remodeling regulator
chr11_-_32088002 9.92 ENSRNOT00000002732
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr1_+_190229528 9.79 ENSRNOT00000088121
Abca16
ATP-binding cassette, subfamily A (ABC1), member 16
chr5_-_64718131 9.57 ENSRNOT00000088211
Acnat1
acyl-coenzyme A amino acid N-acyltransferase 1
chr17_-_27602934 9.37 ENSRNOT00000079298
Rreb1
ras responsive element binding protein 1
chr8_+_119261747 9.18 ENSRNOT00000079648
AC132539.1

chr8_+_116332796 8.81 ENSRNOT00000021408
Hyal1
hyaluronoglucosaminidase 1
chr8_+_65733400 8.67 ENSRNOT00000089126
Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr17_+_9797907 8.54 ENSRNOT00000021638
Lman2
lectin, mannose-binding 2
chr7_-_117680004 8.28 ENSRNOT00000040422
Slc39a4
solute carrier family 39 member 4
chr2_+_93792601 8.23 ENSRNOT00000014701
ENSRNOT00000077311
Fabp4
fatty acid binding protein 4
chr7_+_130308532 8.18 ENSRNOT00000011941
Miox
myo-inositol oxygenase
chr16_+_8211420 7.93 ENSRNOT00000079609
Oxnad1
oxidoreductase NAD-binding domain containing 1
chr13_-_97173469 7.85 ENSRNOT00000017784
Kif26b
kinesin family member 26B
chr10_+_53570989 7.75 ENSRNOT00000064764
ENSRNOT00000004516
Tmem220
transmembrane protein 220
chr16_-_47535358 7.69 ENSRNOT00000040731
Cldn22
claudin 22
chr3_-_113376751 7.59 ENSRNOT00000030019
Catsper2
cation channel, sperm associated 2
chr19_-_50220455 7.56 ENSRNOT00000079760
Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr6_+_98284170 7.46 ENSRNOT00000031979
Rhoj
ras homolog family member J
chr18_+_63023930 7.46 ENSRNOT00000085655
Impa2
inositol monophosphatase 2
chr1_+_101427195 7.41 ENSRNOT00000028271
Gys1
glycogen synthase 1
chr1_-_199716205 7.30 ENSRNOT00000027290
RGD1310127
similar to cDNA sequence BC017158
chr3_-_153952108 7.10 ENSRNOT00000050465
Adig
adipogenin
chr1_-_263959318 7.10 ENSRNOT00000068007
Pkd2l1
polycystin 2 like 1, transient receptor potential cation channel
chr12_+_13284532 7.08 ENSRNOT00000084045
Zdhhc4
zinc finger, DHHC-type containing 4
chr3_+_60026747 7.07 ENSRNOT00000081881
Scrn3
secernin 3
chr4_+_149261044 6.93 ENSRNOT00000066670
Cxcl12
C-X-C motif chemokine ligand 12
chr5_-_168004724 6.86 ENSRNOT00000024711
Park7
Parkinsonism associated deglycase
chrX_+_54734385 6.77 ENSRNOT00000005023
Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr2_-_211322719 6.74 ENSRNOT00000027493
RGD1310209
similar to KIAA1324 protein
chr2_-_124149621 6.66 ENSRNOT00000023448
ENSRNOT00000084825
ENSRNOT00000023437
Nudt6
nudix hydrolase 6
chr3_-_156777999 6.56 ENSRNOT00000032588
ENSRNOT00000091208
Zhx3
zinc fingers and homeoboxes 3
chr5_-_173680290 6.45 ENSRNOT00000027564
Samd11
sterile alpha motif domain containing 11
chr9_+_23596964 6.39 ENSRNOT00000064279
LOC108351994
exocrine gland-secreted peptide 1-like
chr4_+_181315444 6.35 ENSRNOT00000044147
Ppfibp1
PPFIA binding protein 1
chr15_+_18540913 6.31 ENSRNOT00000010545
Pdhb
pyruvate dehydrogenase (lipoamide) beta
chr1_-_199655147 6.31 ENSRNOT00000026979
LOC103691238
zinc finger protein 239-like
chr6_+_99817431 6.26 ENSRNOT00000009621
Churc1
churchill domain containing 1
chr10_+_39435227 6.24 ENSRNOT00000042144
ENSRNOT00000077185
P4ha2
prolyl 4-hydroxylase subunit alpha 2
chr15_-_4454958 6.19 ENSRNOT00000070933
Nudt13
nudix hydrolase 13
chr10_-_4249739 6.17 ENSRNOT00000003150
Snx29
sorting nexin 29
chr8_-_47339343 6.11 ENSRNOT00000081007
Arhgef12
Rho guanine nucleotide exchange factor 12
chr8_-_123371257 6.03 ENSRNOT00000017243
Stt3b
STT3B, catalytic subunit of the oligosaccharyltransferase complex
chr9_+_17728816 5.84 ENSRNOT00000065754
Capn11
calpain 11
chr16_-_6077978 5.80 ENSRNOT00000020823
Il17rb
interleukin 17 receptor B
chr18_+_16146447 5.78 ENSRNOT00000022117
Galnt1
polypeptide N-acetylgalactosaminyltransferase 1
chr5_-_171327450 5.73 ENSRNOT00000088710
Ccdc27
coiled-coil domain containing 27
chr1_+_267689328 5.73 ENSRNOT00000077738
Cfap58
cilia and flagella associated protein 58
chr8_+_116054465 5.73 ENSRNOT00000040056
Cish
cytokine inducible SH2-containing protein
chr3_-_171893901 5.63 ENSRNOT00000091966
Apcdd1l
APC down-regulated 1 like
chr10_-_60275762 5.53 ENSRNOT00000074380
Olr1498
olfactory receptor 1498
chr2_-_259382765 5.43 ENSRNOT00000091407
St6galnac3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr4_+_56337695 5.41 ENSRNOT00000071926
Lep
leptin
chr6_-_139973811 5.40 ENSRNOT00000082875
Ighv5-2
immunoglobulin heavy variable 5-2
chr7_+_38858062 5.38 ENSRNOT00000006234
Kera
keratocan
chr1_+_202770775 5.37 ENSRNOT00000027704
Wdr11
WD repeat domain 11
chr10_-_60126696 5.28 ENSRNOT00000026857
Olr1485
olfactory receptor 1485
chr1_+_237574788 5.26 ENSRNOT00000042738
AABR07006504.1

chr7_-_114590119 5.21 ENSRNOT00000079599
Ptk2
protein tyrosine kinase 2
chr14_-_16903242 5.16 ENSRNOT00000003001
Shroom3
shroom family member 3
chr3_-_35801614 5.10 ENSRNOT00000066058
Mmadhc
methylmalonic aciduria and homocystinuria, cblD type
chr13_+_103268068 5.08 ENSRNOT00000088921
ENSRNOT00000003249
Bpnt1
3'(2'), 5'-bisphosphate nucleotidase 1
chr8_-_76452554 5.06 ENSRNOT00000079815
Gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr20_-_30947484 5.04 ENSRNOT00000065614
Pald1
phosphatase domain containing, paladin 1
chr20_+_3553455 4.91 ENSRNOT00000090080
Ddr1
discoidin domain receptor tyrosine kinase 1
chrX_-_147472677 4.67 ENSRNOT00000072063
Gm6760
predicted gene 6760
chr4_-_165747201 4.66 ENSRNOT00000007435
Tas2r130
taste receptor, type 2, member 130
chr14_-_85772762 4.54 ENSRNOT00000015627
Ccdc117
coiled-coil domain containing 117
chr11_-_65350442 4.53 ENSRNOT00000003773
Gpr156
G protein-coupled receptor 156
chr7_-_73450262 4.48 ENSRNOT00000006943
Nipal2
NIPA-like domain containing 2
chr6_-_71199110 4.30 ENSRNOT00000081883
Prkd1
protein kinase D1
chr20_+_26755911 4.20 ENSRNOT00000083017
Herc4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr5_-_157573183 4.15 ENSRNOT00000064418
Minos1
mitochondrial inner membrane organizing system 1
chr8_-_63750531 4.12 ENSRNOT00000009496
Neo1
neogenin 1
chr14_+_76866135 4.01 ENSRNOT00000037291
Zfp518b
zinc finger protein 518B
chr4_+_14212925 3.95 ENSRNOT00000076946
LOC103690020
platelet glycoprotein 4-like
chr5_+_79367663 3.92 ENSRNOT00000011508
Atp6v1g1
ATPase H+ transporting V1 subunit G1
chr1_-_72129269 3.85 ENSRNOT00000049179
Vom1r35
vomeronasal 1 receptor 35
chr4_+_45000973 3.82 ENSRNOT00000084736
ENSRNOT00000080880
ST7
suppression of tumorigenicity 7
chr13_+_100214353 3.77 ENSRNOT00000073693
LOC686031
hypothetical protein LOC686031
chr19_-_30821999 3.75 ENSRNOT00000072648
Gm8797
predicted pseudogene 8797
chr3_-_76187045 3.72 ENSRNOT00000075650
LOC686683
similar to olfactory receptor 73
chr10_-_46582854 3.72 ENSRNOT00000004753
Srebf1
sterol regulatory element binding transcription factor 1
chr20_-_831447 3.69 ENSRNOT00000000976
Olr1693
olfactory receptor 1693
chr10_+_109893700 3.67 ENSRNOT00000082551
Lrrc45
leucine rich repeat containing 45
chr19_+_38768467 3.60 ENSRNOT00000027346
Cdh1
cadherin 1
chr10_+_92769031 3.59 ENSRNOT00000090759
AABR07030543.1

chr12_+_44046454 3.57 ENSRNOT00000064756
Fbxw8
F-box and WD repeat domain containing 8
chr14_-_6148830 3.57 ENSRNOT00000075091
ENSRNOT00000092683
LOC100366030
rCG37858-like
chr14_+_22251499 3.54 ENSRNOT00000087991
ENSRNOT00000002705
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_+_267618565 3.49 ENSRNOT00000076251
Gsto2
glutathione S-transferase omega 2
chr1_-_190965115 3.48 ENSRNOT00000023483
AC103221.1

chr10_-_46206135 3.47 ENSRNOT00000091471
Cops3
COP9 signalosome subunit 3
chr1_+_172822544 3.42 ENSRNOT00000090018
AABR07004960.1

chr3_-_21027947 3.41 ENSRNOT00000051973
Olr421
olfactory receptor 421
chr5_-_164714145 3.39 ENSRNOT00000055680
LOC100911485
mitofusin-2-like
chr19_-_25961666 3.39 ENSRNOT00000004091
Calr
calreticulin
chr13_-_88307988 3.38 ENSRNOT00000003812
Hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
chr8_-_43524220 3.35 ENSRNOT00000088755
Olr1315
olfactory receptor 1315
chr13_+_52889737 3.35 ENSRNOT00000074366
Cacna1s
calcium voltage-gated channel subunit alpha1 S
chr10_+_49368314 3.33 ENSRNOT00000004392
Cdrt4
CMT1A duplicated region transcript 4
chr7_-_49732764 3.30 ENSRNOT00000006453
Myf5
myogenic factor 5
chr8_-_116764780 3.25 ENSRNOT00000026216
Fam212a
family with sequence similarity 212, member A
chr20_-_2913785 3.23 ENSRNOT00000088584
Btnl7
butyrophilin-like 7
chrX_+_72685300 3.22 ENSRNOT00000076215
Dmrtc1c1
DMRT-like family C1c1
chr6_-_122239614 3.21 ENSRNOT00000005015
Galc
galactosylceramidase
chr9_-_63291350 3.21 ENSRNOT00000058831
Hsfy2
heat shock transcription factor, Y linked 2
chr7_-_117289961 3.12 ENSRNOT00000042642
Plec
plectin
chr1_+_264260505 3.09 ENSRNOT00000018815
Wnt8b
wingless-type MMTV integration site family, member 8B
chr1_-_229804614 3.02 ENSRNOT00000049665
Olr343
olfactory receptor 343
chr5_-_75057752 2.96 ENSRNOT00000016447
Txn1
thioredoxin 1
chr5_+_172648950 2.96 ENSRNOT00000055361
Faap20
Fanconi anemia core complex associated protein 20
chr8_-_42979305 2.88 ENSRNOT00000073449
LOC100910439
olfactory receptor 146-like
chr17_-_15519060 2.85 ENSRNOT00000093624
Aspnl1
asporin-like 1
chr3_-_73493621 2.75 ENSRNOT00000071782
Olr482
olfactory receptor 482
chr6_-_104290579 2.75 ENSRNOT00000066014
Erh
enhancer of rudimentary homolog (Drosophila)
chr3_+_77072410 2.72 ENSRNOT00000078540
Olr649
olfactory receptor 649
chr20_+_734642 2.72 ENSRNOT00000073543
Olr1688
olfactory receptor 1688
chr3_-_165537940 2.71 ENSRNOT00000071119
ENSRNOT00000070964
Sall4
spalt-like transcription factor 4
chr2_-_29121104 2.70 ENSRNOT00000020543
Tnpo1
transportin 1
chrX_+_106230013 2.65 ENSRNOT00000067828
AABR07040617.1

chr2_-_123851854 2.64 ENSRNOT00000023327
Il2
interleukin 2
chr10_+_14481393 2.64 ENSRNOT00000091072
Ptx4
pentraxin 4
chr10_+_55997614 2.60 ENSRNOT00000013071
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr15_+_108453147 2.59 ENSRNOT00000018486
Timm8a2
translocase of inner mitochondrial membrane 8A2
chrX_+_115721251 2.57 ENSRNOT00000060090
Trpc5os
TRPC5 opposite strand
chr3_-_76279104 2.56 ENSRNOT00000007796
Olr608
olfactory receptor 608
chr5_-_58288125 2.53 ENSRNOT00000068752
Fam205a
family with sequence similarity 205, member A
chr1_-_149778698 2.50 ENSRNOT00000089920
LOC100909935
olfactory receptor 6F1-like
chr4_+_71512695 2.50 ENSRNOT00000037220
Tas2r139
taste receptor, type 2, member 139
chr1_+_207508414 2.48 ENSRNOT00000054896
Nps
neuropeptide S
chr2_-_35435719 2.48 ENSRNOT00000087827
LOC100910041
olfactory receptor 146-like
chr6_-_142385773 2.47 ENSRNOT00000071555
AABR07065814.7

Network of associatons between targets according to the STRING database.

First level regulatory network of Meis1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.6 34.8 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
6.4 19.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
5.4 27.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
5.4 26.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
5.1 25.3 GO:0060018 astrocyte fate commitment(GO:0060018)
5.0 19.9 GO:0006565 L-serine catabolic process(GO:0006565)
4.8 24.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
4.3 68.4 GO:0051923 sulfation(GO:0051923)
4.2 12.5 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
4.1 24.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
4.0 32.3 GO:0007262 STAT protein import into nucleus(GO:0007262)
3.7 11.0 GO:0051977 lysophospholipid transport(GO:0051977)
3.4 27.4 GO:0030321 transepithelial chloride transport(GO:0030321)
2.9 20.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
2.9 11.5 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
2.8 13.9 GO:0001579 medium-chain fatty acid transport(GO:0001579)
2.8 8.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
2.6 84.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
2.5 10.2 GO:1900158 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
2.5 15.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
2.5 9.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.4 14.5 GO:0003383 apical constriction(GO:0003383)
2.3 18.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
2.3 9.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
2.3 11.6 GO:0015793 glycerol transport(GO:0015793)
2.3 83.7 GO:0017144 drug metabolic process(GO:0017144)
2.3 13.9 GO:0008050 female courtship behavior(GO:0008050)
2.3 20.6 GO:0052697 xenobiotic glucuronidation(GO:0052697)
2.3 6.9 GO:1903122 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) TRAIL receptor biosynthetic process(GO:0045557) regulation of TRAIL receptor biosynthetic process(GO:0045560) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
2.3 20.3 GO:0070633 transepithelial transport(GO:0070633)
2.2 8.8 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
2.1 19.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
2.0 7.8 GO:0072092 ureteric bud invasion(GO:0072092)
1.8 23.5 GO:0071468 cellular response to acidic pH(GO:0071468)
1.7 6.9 GO:1990478 response to ultrasound(GO:1990478)
1.7 5.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
1.6 1.6 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
1.5 16.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
1.4 37.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
1.4 10.9 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
1.3 5.2 GO:0007172 signal complex assembly(GO:0007172)
1.2 18.4 GO:0051639 actin filament network formation(GO:0051639)
1.2 4.9 GO:0060066 oviduct development(GO:0060066)
1.2 13.1 GO:0002934 desmosome organization(GO:0002934)
1.2 5.8 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
1.2 5.8 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
1.1 44.7 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
1.1 3.4 GO:0002397 MHC class I protein complex assembly(GO:0002397)
1.1 20.2 GO:0070166 enamel mineralization(GO:0070166)
1.0 6.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.0 10.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.0 17.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.9 7.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.9 17.7 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.9 3.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.8 8.9 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.8 2.3 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.8 2.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.7 8.2 GO:0006020 inositol metabolic process(GO:0006020)
0.7 4.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.7 7.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.7 5.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.7 2.6 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.6 4.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.6 8.7 GO:0050667 homocysteine metabolic process(GO:0050667)
0.6 1.7 GO:0048014 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.6 5.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.6 6.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.5 6.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 3.2 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.5 9.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.5 1.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.5 3.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.5 2.5 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.5 6.8 GO:0030238 male sex determination(GO:0030238)
0.4 3.7 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.4 3.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.4 6.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.4 1.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.4 2.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 3.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 1.5 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.4 1.9 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) somatotropin secreting cell differentiation(GO:0060126)
0.4 8.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.4 13.2 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.4 7.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.3 4.5 GO:0015693 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
0.3 3.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.3 7.6 GO:0048240 sperm capacitation(GO:0048240)
0.3 3.5 GO:0000338 protein deneddylation(GO:0000338)
0.3 8.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 4.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 1.4 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.3 0.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 5.4 GO:0097503 sialylation(GO:0097503)
0.2 8.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 8.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 10.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 3.0 GO:0019985 translesion synthesis(GO:0019985)
0.2 4.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 2.2 GO:0007614 short-term memory(GO:0007614)
0.2 1.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 3.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 10.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 18.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.2 7.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 2.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 5.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 1.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.9 GO:1990403 embryonic brain development(GO:1990403)
0.1 11.2 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 8.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 1.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.9 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.6 GO:0031167 rRNA methylation(GO:0031167)
0.1 1.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 2.8 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1 2.0 GO:0016180 snRNA processing(GO:0016180)
0.1 5.2 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 1.0 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.1 2.8 GO:1901998 toxin transport(GO:1901998)
0.1 83.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.2 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824)
0.1 0.3 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 1.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 7.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 3.1 GO:0015918 sterol transport(GO:0015918)
0.0 6.8 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.7 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 17.0 GO:0055114 oxidation-reduction process(GO:0055114)
0.0 1.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 1.9 GO:0000209 protein polyubiquitination(GO:0000209)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 31.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
4.0 12.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.9 8.8 GO:0036117 hyaluranon cable(GO:0036117)
2.4 14.5 GO:0033269 internode region of axon(GO:0033269)
1.7 8.7 GO:0043293 apoptosome(GO:0043293)
1.6 6.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.4 24.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
1.3 16.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.3 11.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
1.1 11.0 GO:0045179 apical cortex(GO:0045179)
1.1 7.6 GO:0036128 CatSper complex(GO:0036128)
0.8 3.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.8 22.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.7 6.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.7 6.8 GO:0042788 polysomal ribosome(GO:0042788)
0.6 2.6 GO:0031417 NatC complex(GO:0031417)
0.6 17.1 GO:0031528 microvillus membrane(GO:0031528)
0.6 3.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.6 20.1 GO:0008305 integrin complex(GO:0008305)
0.6 42.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.5 1.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.5 29.3 GO:0034707 chloride channel complex(GO:0034707)
0.4 2.3 GO:1990246 uniplex complex(GO:1990246)
0.4 3.6 GO:0043219 lateral loop(GO:0043219)
0.3 18.5 GO:0005871 kinesin complex(GO:0005871)
0.3 20.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 20.6 GO:0031526 brush border membrane(GO:0031526)
0.2 8.8 GO:0046930 pore complex(GO:0046930)
0.2 1.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 3.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 3.1 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 8.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 24.3 GO:0043296 apical junction complex(GO:0043296)
0.2 4.3 GO:0000421 autophagosome membrane(GO:0000421)
0.2 1.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 13.2 GO:0016234 inclusion body(GO:0016234)
0.1 3.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 19.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 16.8 GO:0016363 nuclear matrix(GO:0016363)
0.1 23.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 6.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 8.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.9 GO:0034704 calcium channel complex(GO:0034704)
0.1 4.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 7.5 GO:0005811 lipid particle(GO:0005811)
0.1 2.0 GO:0032039 integrator complex(GO:0032039)
0.1 15.6 GO:0005768 endosome(GO:0005768)
0.1 77.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 5.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 13.1 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.1 GO:0005859 muscle myosin complex(GO:0005859)
0.1 2.7 GO:0034399 nuclear periphery(GO:0034399)
0.1 9.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 5.2 GO:0014704 intercalated disc(GO:0014704)
0.1 17.6 GO:0005925 focal adhesion(GO:0005925)
0.1 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 163.6 GO:0070062 extracellular exosome(GO:0070062)
0.1 5.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.5 GO:0071546 pi-body(GO:0071546)
0.0 2.1 GO:0045095 keratin filament(GO:0045095)
0.0 54.7 GO:0005739 mitochondrion(GO:0005739)
0.0 4.9 GO:0005769 early endosome(GO:0005769)
0.0 20.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 79.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.1 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 3.2 GO:0030054 cell junction(GO:0030054)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 31.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
8.0 24.0 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
6.6 19.9 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
5.9 17.7 GO:0019807 aspartoacylase activity(GO:0019807)
5.6 67.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
5.4 26.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
5.3 15.8 GO:0070573 metallodipeptidase activity(GO:0070573)
4.6 13.9 GO:0008458 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
4.2 12.5 GO:0042015 interleukin-20 binding(GO:0042015)
4.1 20.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
3.9 11.6 GO:0015254 glycerol channel activity(GO:0015254)
3.8 11.5 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
3.0 21.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
3.0 51.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
2.7 24.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.6 84.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
2.6 10.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
2.3 16.4 GO:0031433 telethonin binding(GO:0031433)
2.3 6.9 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
2.2 10.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
2.0 10.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
1.9 7.5 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
1.8 56.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.8 11.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.8 8.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.7 6.8 GO:0050682 AF-2 domain binding(GO:0050682)
1.6 6.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.6 6.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
1.4 27.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.3 10.5 GO:0031419 cobalamin binding(GO:0031419)
1.3 6.4 GO:0042731 PH domain binding(GO:0042731)
1.3 5.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441) inositol bisphosphate phosphatase activity(GO:0016312)
1.3 5.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.3 13.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
1.2 3.7 GO:0032810 sterol response element binding(GO:0032810)
1.2 17.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.1 4.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.1 3.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
1.1 5.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.1 15.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.1 7.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.9 3.5 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.9 6.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.8 46.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.7 5.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.7 26.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6 7.1 GO:0016805 dipeptidase activity(GO:0016805)
0.6 8.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.6 18.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.5 2.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 6.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 2.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.5 1.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5 5.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 8.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.5 11.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.5 9.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 14.6 GO:0003785 actin monomer binding(GO:0003785)
0.5 2.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.5 34.5 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.5 73.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.4 8.5 GO:0005537 mannose binding(GO:0005537)
0.4 5.2 GO:0008432 JUN kinase binding(GO:0008432)
0.4 1.3 GO:0004096 catalase activity(GO:0004096)
0.4 8.2 GO:0008199 ferric iron binding(GO:0008199)
0.4 1.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.4 4.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 4.1 GO:0039706 co-receptor binding(GO:0039706)
0.4 17.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 3.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.3 1.3 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.3 1.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 20.0 GO:0009055 electron carrier activity(GO:0009055)
0.3 4.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 7.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.3 30.5 GO:0005178 integrin binding(GO:0005178)
0.2 5.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 7.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 27.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 4.3 GO:0004697 protein kinase C activity(GO:0004697)
0.2 3.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 5.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 4.9 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 1.4 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 2.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 4.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 9.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 56.4 GO:0005549 odorant binding(GO:0005549)
0.1 13.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 2.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 3.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.3 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 3.1 GO:0005109 frizzled binding(GO:0005109)
0.1 11.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.0 GO:0016917 GABA receptor activity(GO:0016917)
0.1 7.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 6.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 3.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 8.0 GO:0016853 isomerase activity(GO:0016853)
0.0 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 3.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 4.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 3.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 1.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 26.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 5.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.4 26.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
1.3 27.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.9 24.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.5 5.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.5 35.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.4 6.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 12.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 13.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 18.8 PID FGF PATHWAY FGF signaling pathway
0.2 7.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 13.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 6.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 4.2 PID IL27 PATHWAY IL27-mediated signaling events
0.2 10.2 PID BMP PATHWAY BMP receptor signaling
0.2 6.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.8 PID IGF1 PATHWAY IGF1 pathway
0.1 8.2 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 5.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 4.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 26.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.3 26.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
1.3 67.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
1.3 24.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.0 33.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.0 11.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.9 24.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.8 24.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.7 10.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.7 18.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.6 11.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.6 13.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.6 9.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.5 8.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5 6.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 4.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.4 5.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 5.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 5.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.4 5.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 4.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 10.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 16.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 4.7 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.2 5.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 6.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 19.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 6.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 6.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 7.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 15.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 7.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 11.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 5.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 4.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation