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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Meis2

Z-value: 1.12

Motif logo

Transcription factors associated with Meis2

Gene Symbol Gene ID Gene Info
ENSRNOG00000004730 Meis homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meis2rn6_v1_chr3_-_107760550_107760589-0.284.6e-07Click!

Activity profile of Meis2 motif

Sorted Z-values of Meis2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_118108864 32.96 ENSRNOT00000006184
myoglobin
chr9_-_73958480 24.20 ENSRNOT00000017838
myosin, light chain 1
chr13_-_47397890 21.48 ENSRNOT00000005505
complement component 4 binding protein, beta
chr9_+_14529218 21.34 ENSRNOT00000016893
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chrX_-_23187341 19.38 ENSRNOT00000000180
5'-aminolevulinate synthase 2
chr10_-_15590220 18.22 ENSRNOT00000048977
hemoglobin alpha, adult chain 2
chr3_-_176666282 17.64 ENSRNOT00000016947
eukaryotic translation elongation factor 1 alpha 2
chr4_-_99125111 17.20 ENSRNOT00000009184
SET and MYND domain containing 1
chr1_-_168972725 16.25 ENSRNOT00000090422
hemoglobin subunit beta
chr2_-_105089659 15.59 ENSRNOT00000043381
carboxypeptidase B1
chr13_+_52625441 15.32 ENSRNOT00000012095
troponin I1, slow skeletal type
chr4_-_69268336 14.93 ENSRNOT00000018042
protease, serine, 3B
chr1_-_143398093 14.47 ENSRNOT00000078916
fibronectin type III and SPRY domain containing 2
chr13_-_98478327 14.46 ENSRNOT00000030135
coenzyme Q8A
chr7_-_29152442 14.40 ENSRNOT00000079774
myosin binding protein C, slow type
chr2_+_46980976 14.40 ENSRNOT00000083668
ENSRNOT00000082990
molybdenum cofactor synthesis 2
chr2_-_96668222 13.48 ENSRNOT00000016567
cAMP-dependent protein kinase inhibitor alpha
chr20_-_5805627 13.14 ENSRNOT00000085996
colipase
chr14_+_22251499 13.09 ENSRNOT00000087991
ENSRNOT00000002705
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_+_147713892 13.06 ENSRNOT00000092985
ENSRNOT00000054742
ENSRNOT00000074103
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr9_+_37727942 12.91 ENSRNOT00000016511
ENSRNOT00000074276
myotilin-like
chr1_+_101324652 12.72 ENSRNOT00000028116
histidine rich calcium binding protein
chr3_+_58632476 12.51 ENSRNOT00000010630
Rap guanine nucleotide exchange factor 4
chr10_+_53621375 11.93 ENSRNOT00000004147
myosin heavy chain 3
chr7_-_117289961 11.64 ENSRNOT00000042642
plectin
chr19_-_43911057 11.42 ENSRNOT00000026017
chymotrypsinogen B1
chr4_-_164453171 11.41 ENSRNOT00000077539
ENSRNOT00000083610
ENSRNOT00000079975
Ly49 stimulatory receptor 6
chr1_-_195096694 11.41 ENSRNOT00000088874
SNRPN upstream reading frame
chr20_-_5806097 11.14 ENSRNOT00000000611
colipase
chr7_-_118933812 11.05 ENSRNOT00000031951
apolipoprotein L 9a
chr4_-_60358562 10.88 ENSRNOT00000018001
coiled-coil-helix-coiled-coil-helix domain containing 3
chr9_-_82419288 10.71 ENSRNOT00000004797
tubulin, alpha 4A
chr5_-_77749613 10.59 ENSRNOT00000075988
major urinary protein 5
chr2_-_227411964 10.57 ENSRNOT00000019931
synaptopodin 2
chr12_-_11733099 10.44 ENSRNOT00000051244
ENSRNOT00000087257
cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1
chr17_-_65955606 10.36 ENSRNOT00000067949
ENSRNOT00000023601
ryanodine receptor 2
chr2_-_52282548 10.29 ENSRNOT00000033627
nicotinamide nucleotide transhydrogenase
chrX_+_143097525 10.03 ENSRNOT00000004559
coagulation factor IX
chr1_-_195096460 10.03 ENSRNOT00000077253
small nuclear ribonucleoprotein polypeptide N
chr3_-_113519780 9.96 ENSRNOT00000064663
FERM domain containing 5
chr4_+_166833320 9.95 ENSRNOT00000031438
taste receptor, type 2, member 120
chr13_-_37287458 9.73 ENSRNOT00000003391
insulin induced gene 2
chr1_-_128695796 9.62 ENSRNOT00000076329
synemin
chr1_+_264893162 9.58 ENSRNOT00000021714
T-cell leukemia, homeobox 1
chr12_+_30450316 9.45 ENSRNOT00000001222
phosphorylase kinase, gamma 1
chr2_-_104461863 9.36 ENSRNOT00000016953
corticotropin releasing hormone
chr13_+_52662996 8.99 ENSRNOT00000047682
troponin T2, cardiac type
chr4_-_113610243 8.98 ENSRNOT00000008813
hexokinase 2
chr3_-_125213607 8.82 ENSRNOT00000078070
glycerophosphocholine phosphodiesterase 1
chr3_+_72238981 8.78 ENSRNOT00000011006
solute carrier family 43 member 1
chr4_-_166869399 8.62 ENSRNOT00000007521
taste receptor, type 2, member 121
chr2_-_19808937 8.41 ENSRNOT00000044237
ATPase H+ transporting accessory protein 1 like
chr14_-_80130139 8.31 ENSRNOT00000091652
ENSRNOT00000010482
actin binding LIM protein family, member 2
chr19_+_37235001 8.19 ENSRNOT00000020908
nucleolar protein 3
chr15_-_35417273 8.18 ENSRNOT00000083961
ENSRNOT00000041430
granzyme B
chr7_-_135630654 8.17 ENSRNOT00000047388
ENSRNOT00000088223
ENSRNOT00000074793
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr10_-_15603649 8.13 ENSRNOT00000051483
hemoglobin alpha, adult chain 2
chr5_-_105010857 7.83 ENSRNOT00000009749
perilipin 2
chr9_-_89193821 7.77 ENSRNOT00000090881
SPHK1 interactor, AKAP domain containing
chrX_+_45420596 7.75 ENSRNOT00000051897
steroid sulfatase (microsomal), isozyme S
chr17_+_28504623 7.62 ENSRNOT00000021568
coagulation factor XIII A1 chain
chr8_+_119228612 7.62 ENSRNOT00000078439
ENSRNOT00000043737
leucine rich repeat containing 2
chr2_+_181987217 7.44 ENSRNOT00000034521
fibrinogen gamma chain
chr13_+_89586283 7.43 ENSRNOT00000079355
ENSRNOT00000049873
nuclear receptor subfamily 1, group I, member 3
chr15_-_36472327 7.21 ENSRNOT00000032601
ENSRNOT00000059660
granzyme-like protein 1-like
chr17_+_42241159 7.13 ENSRNOT00000024878
acyl-CoA thioesterase 13
chr1_+_68176904 7.08 ENSRNOT00000044950
vomeronasal 1 receptor 28
chr4_-_164691405 7.05 ENSRNOT00000090979
ENSRNOT00000091932
ENSRNOT00000078219
Ly49 stimulatory receptor 4
Ly49 inhibitory receptor 2
chr4_+_163349125 6.98 ENSRNOT00000084823
killer cell lectin-like receptor, family E, member 1
chr2_+_205568935 6.91 ENSRNOT00000025248
adenosine monophosphate deaminase 1
chr7_-_29171783 6.85 ENSRNOT00000079235
myosin binding protein C, slow type
chr6_+_27589657 6.79 ENSRNOT00000038649
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr1_+_177048655 6.75 ENSRNOT00000081595
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr3_-_8979889 6.65 ENSRNOT00000065128
carnitine O-acetyltransferase
chr11_-_81444375 6.62 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr2_+_211337271 6.51 ENSRNOT00000045155
cytochrome c oxidase subunit 6B1
chr16_+_75572070 6.45 ENSRNOT00000043486
defensin beta 52
chr10_+_66099531 6.44 ENSRNOT00000056192
LYR motif containing 9
chrX_-_13601069 6.39 ENSRNOT00000004686
ornithine carbamoyltransferase
chr8_-_133128290 6.28 ENSRNOT00000008783
chemokine (C-C motif) receptor 1-like 1
chr9_-_54327958 6.17 ENSRNOT00000019465
signal transducer and activator of transcription 1
chr13_-_52266100 6.14 ENSRNOT00000087532

chr17_-_87826421 6.10 ENSRNOT00000068156
Rho GTPase activating protein 21
chr16_+_26906716 6.04 ENSRNOT00000064297
carboxypeptidase E
chr18_+_17043903 6.01 ENSRNOT00000068139
formin homology 2 domain containing 3
chr11_-_38420032 5.87 ENSRNOT00000002209
ENSRNOT00000080681
C2 calcium-dependent domain containing 2
chr9_+_43259709 5.78 ENSRNOT00000022487
cytochrome c oxidase subunit 5B
chr7_-_71269869 5.68 ENSRNOT00000037030
ubiquinol-cytochrome c reductase binding protein
chr1_+_153861569 5.64 ENSRNOT00000023329
malic enzyme 3
chr16_+_54332660 5.58 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr4_+_181103774 5.57 ENSRNOT00000084207
ENSRNOT00000055473
ENSRNOT00000077619
aryl hydrocarbon receptor nuclear translocator-like 2
chr6_-_141062581 5.55 ENSRNOT00000073446

chr8_+_119261747 5.55 ENSRNOT00000079648

chr14_-_84937725 5.50 ENSRNOT00000083839
ubiquinol-cytochrome c reductase, complex III subunit X
chr8_+_87211819 5.47 ENSRNOT00000086093
LRRGT00022-like
chr1_+_153861948 5.47 ENSRNOT00000087067
malic enzyme 3
chr14_+_5928737 5.32 ENSRNOT00000071877
ENSRNOT00000040985
ENSRNOT00000074889
macrophage activation 2 like
chr20_+_10265806 5.29 ENSRNOT00000001564
ENSRNOT00000086272
NADH:ubiquinone oxidoreductase subunit V3
chr3_+_72329967 5.27 ENSRNOT00000090256
solute carrier family 43, member 3
chr9_-_4945352 5.26 ENSRNOT00000082530
sulfotransferase family 1C member 3
chr5_+_147476221 5.14 ENSRNOT00000010730
syncoilin, intermediate filament protein
chr12_+_19512591 5.13 ENSRNOT00000060024
similar to family with sequence similarity 55, member C
chr7_+_118712035 5.11 ENSRNOT00000074245
apolipoprotein L3-like
chr1_+_141218095 5.06 ENSRNOT00000051411
similar to 6.8 kDa mitochondrial proteolipid
chr4_-_164306500 5.06 ENSRNOT00000080133
Ly49 inhibitory receptor 5
chr13_+_113373578 5.06 ENSRNOT00000009900
plexin A2
chr17_+_8489266 5.00 ENSRNOT00000016252
leukocyte cell-derived chemotaxin 2
chr19_+_26016382 4.95 ENSRNOT00000004601
Kruppel like factor 1
chr12_+_15890170 4.85 ENSRNOT00000001654
G protein subunit alpha 12
chr13_-_47831110 4.76 ENSRNOT00000061070
mitogen-activated protein kinase-activated protein kinase 2
chr7_+_118895405 4.74 ENSRNOT00000092095
similar to apolipoprotein L2; apolipoprotein L-II
chr1_+_40982862 4.71 ENSRNOT00000026367
ENSRNOT00000092953
acidic residue methyltransferase 1
chr13_-_49313940 4.64 ENSRNOT00000012190
contactin 2
chr2_-_105047984 4.63 ENSRNOT00000014970
carboxypeptidase A3
chr16_+_23553647 4.63 ENSRNOT00000041994
pleckstrin and Sec7 domain containing 3
chr9_-_99667689 4.60 ENSRNOT00000046464
olfactory receptor 1344
chr10_-_34439470 4.52 ENSRNOT00000072081
butyrophilin-like 9
chr10_-_109795697 4.49 ENSRNOT00000054952
phosphate cytidylyltransferase 2, ethanolamine
chr14_+_22375955 4.48 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr10_-_110585376 4.48 ENSRNOT00000054917
Rab40b, member RAS oncogene family
chr1_-_278042312 4.46 ENSRNOT00000018693
actin-binding LIM protein 1
chr18_+_56414488 4.45 ENSRNOT00000088988
colony stimulating factor 1 receptor
chr10_-_67479077 4.45 ENSRNOT00000090278
transcription elongation factor, mitochondrial
chr15_-_34392066 4.44 ENSRNOT00000027315
transglutaminase 1
chr3_+_100768637 4.39 ENSRNOT00000083542
brain-derived neurotrophic factor
chr4_-_165317573 4.39 ENSRNOT00000087529
ENSRNOT00000080017
killer cell lectin-like receptor, subfamily A, member 5
chr3_-_119075606 4.36 ENSRNOT00000041569
ENSRNOT00000086724
histidine decarboxylase
chr8_-_43470377 4.32 ENSRNOT00000050312
olfactory receptor 149
chr7_-_3875067 4.31 ENSRNOT00000072301
olfactory receptor 883
chr9_-_10338216 4.28 ENSRNOT00000070862
NADH:ubiquinone oxidoreductase subunit A11
chr1_-_128695995 4.26 ENSRNOT00000077020
synemin
chr10_-_36452378 4.26 ENSRNOT00000004872
PROP paired-like homeobox 1
chr4_+_149261044 4.26 ENSRNOT00000066670
C-X-C motif chemokine ligand 12
chrX_-_137015266 4.26 ENSRNOT00000040369
olfactory receptor 1767
chr8_+_116857684 4.26 ENSRNOT00000026711
macrophage stimulating 1
chr1_-_212548730 4.24 ENSRNOT00000089729
calcyon neuron-specific vesicular protein
chr14_-_87701884 4.23 ENSRNOT00000079338
motile sperm domain containing 1
chr4_+_32495321 4.21 ENSRNOT00000015286
succinate dehydrogenase complex assembly factor 3
chr8_-_43524220 4.20 ENSRNOT00000088755
olfactory receptor 1315
chr3_+_60026747 4.17 ENSRNOT00000081881
secernin 3
chr11_-_67702955 4.15 ENSRNOT00000084540
ENSRNOT00000078285
karyopherin subunit alpha 1
chr18_+_61490031 4.15 ENSRNOT00000022958
SEC11 homolog C, signal peptidase complex subunit
chr2_+_46140482 4.15 ENSRNOT00000072858
olfactory receptor 1262
chr20_-_1878126 4.12 ENSRNOT00000000995
ubiquitin D
chr5_-_157518511 4.12 ENSRNOT00000070865
ENSRNOT00000078028
5-hydroxytryptamine receptor 6
chr7_+_32193086 4.12 ENSRNOT00000079193

chr4_-_31730386 4.12 ENSRNOT00000013817
solute carrier family 25 member 13
chr18_-_57920169 4.10 ENSRNOT00000040936
serine peptidase inhibitor, Kazal type 7
chr7_-_70661891 4.10 ENSRNOT00000010240
inhibin beta C subunit
chr1_-_185143272 4.08 ENSRNOT00000027752
nucleobindin 2
chr7_-_119712888 4.06 ENSRNOT00000077438
interleukin 2 receptor subunit beta
chr2_+_127770676 4.03 ENSRNOT00000068405
abhydrolase domain containing 18
chr16_+_50152008 4.02 ENSRNOT00000019237
kallikrein B1
chr1_+_68239314 4.00 ENSRNOT00000070823
vomeronasal 1 receptor 109
chr7_-_97977135 4.00 ENSRNOT00000008785
WDYHV motif containing 1
chr8_-_94352246 3.99 ENSRNOT00000013244
malic enzyme 1
chr4_+_102592965 3.98 ENSRNOT00000031103

chr2_+_35310188 3.92 ENSRNOT00000073523
olfactory receptor 147-like
chr10_+_92667869 3.90 ENSRNOT00000082780
ENSRNOT00000073350
integrin subunit beta 3
chrX_-_77675487 3.88 ENSRNOT00000042799
cysteinyl leukotriene receptor 1
chr8_+_118066988 3.88 ENSRNOT00000056161
microtubule-associated protein 4
chr7_+_118962897 3.87 ENSRNOT00000074888
similar to apolipoprotein L2; apolipoprotein L-II
chr6_-_141472746 3.84 ENSRNOT00000048010

chr11_-_32088002 3.83 ENSRNOT00000002732
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr13_-_98530724 3.81 ENSRNOT00000040203
presenilin 2
chr6_+_107460668 3.81 ENSRNOT00000013515
acyl-CoA thioesterase 2
chr6_+_10306405 3.80 ENSRNOT00000090420
ENSRNOT00000080507
endothelial PAS domain protein 1
chr2_-_219628997 3.78 ENSRNOT00000064484
tRNA methyltransferase 13 homolog
chr9_-_4327679 3.78 ENSRNOT00000073468
sulfotransferase 1C1-like
chr4_-_144318580 3.76 ENSRNOT00000007591
ssu-2 homolog
chr2_+_186555632 3.72 ENSRNOT00000052347
Fc receptor-like 1
chr6_-_138640187 3.70 ENSRNOT00000087983

chr20_+_46667121 3.69 ENSRNOT00000089611
sestrin 1
chr11_-_28598179 3.68 ENSRNOT00000070889
keratin-associated protein 26-1-like
chr7_+_123578878 3.68 ENSRNOT00000011316
single-pass membrane protein with aspartate-rich tail 1
chrX_-_156440461 3.65 ENSRNOT00000083951
ribosomal protein L10
chr1_+_88875375 3.65 ENSRNOT00000028284
Tyro protein tyrosine kinase binding protein
chr6_-_139654508 3.65 ENSRNOT00000082576

chr3_+_75559775 3.61 ENSRNOT00000035844
preferentially expressed antigen in melanoma-like 6
chr15_-_28323507 3.61 ENSRNOT00000060539
ribonuclease A family member 13
chr17_+_3991330 3.60 ENSRNOT00000024208
cathepsin Q
chr2_-_210839295 3.55 ENSRNOT00000025994
glutathione S-transferase mu 4
chr6_-_140805551 3.54 ENSRNOT00000080018

chr7_-_18612118 3.54 ENSRNOT00000078122
ENSRNOT00000010197
RAB11B, member RAS oncogene family
chr8_-_73194837 3.54 ENSRNOT00000024885
ENSRNOT00000081450
ENSRNOT00000064613
talin 2
chr6_+_94429068 3.51 ENSRNOT00000008238
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr6_+_139551751 3.51 ENSRNOT00000081684

chr1_+_75693232 3.49 ENSRNOT00000020090
calcium binding protein 5
chr16_+_8207223 3.47 ENSRNOT00000026751
oxidoreductase NAD-binding domain containing 1
chr8_+_2659865 3.47 ENSRNOT00000088553
ENSRNOT00000010243
caspase 12
chr3_+_141927400 3.47 ENSRNOT00000066588

chr2_-_210726179 3.45 ENSRNOT00000025689
glutathione S-transferase, mu 7
chr12_+_41316764 3.45 ENSRNOT00000090867
2'-5'-oligoadenylate synthetase 3
chr10_-_102200596 3.44 ENSRNOT00000081519
family with sequence similarity 104, member A
chr14_+_22517774 3.43 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr19_-_10976396 3.43 ENSRNOT00000073239
NLR family, CARD domain containing 5
chr4_-_132111079 3.40 ENSRNOT00000013719
eukaryotic translation initiation factor 4E family member 3
chr4_+_78639672 3.40 ENSRNOT00000011588
seminal vesicle secretory protein 1
chr4_-_164536556 3.38 ENSRNOT00000087796
Ly49 inhibitory receptor 2
chr18_+_51523758 3.36 ENSRNOT00000078518
GRAM domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Meis2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 33.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
8.0 31.9 GO:1901423 response to benzene(GO:1901423)
7.2 21.5 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
5.3 21.3 GO:0016554 cytidine to uridine editing(GO:0016554)
4.2 12.7 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
4.1 16.2 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
3.5 10.4 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
3.4 13.4 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
3.0 9.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
2.9 17.2 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
2.7 8.2 GO:0060545 positive regulation of necroptotic process(GO:0060545)
2.6 13.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
2.4 9.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.3 7.0 GO:0002838 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
2.3 13.9 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
2.2 6.7 GO:0019417 sulfur oxidation(GO:0019417)
2.2 15.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
2.1 21.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
2.0 26.3 GO:0015671 oxygen transport(GO:0015671)
1.7 6.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.5 4.6 GO:0060167 clustering of voltage-gated potassium channels(GO:0045163) regulation of adenosine receptor signaling pathway(GO:0060167)
1.5 6.2 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
1.5 6.1 GO:0051684 maintenance of Golgi location(GO:0051684)
1.5 4.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.4 4.3 GO:0048850 hypophysis morphogenesis(GO:0048850)
1.3 14.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
1.3 3.9 GO:2000474 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) regulation of opioid receptor signaling pathway(GO:2000474)
1.3 3.9 GO:0051012 microtubule sliding(GO:0051012)
1.3 6.4 GO:0006526 arginine biosynthetic process(GO:0006526)
1.3 15.1 GO:0006108 malate metabolic process(GO:0006108)
1.2 6.0 GO:2000173 insulin processing(GO:0030070) negative regulation of branching morphogenesis of a nerve(GO:2000173)
1.2 14.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
1.2 3.5 GO:0018916 nitrobenzene metabolic process(GO:0018916)
1.2 3.5 GO:0045054 constitutive secretory pathway(GO:0045054)
1.2 6.9 GO:0032264 IMP salvage(GO:0032264)
1.1 4.4 GO:0001692 histamine metabolic process(GO:0001692)
1.1 4.3 GO:1990478 response to ultrasound(GO:1990478)
1.0 3.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.0 10.4 GO:0070989 oxidative demethylation(GO:0070989)
1.0 4.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.0 3.1 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
1.0 4.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.0 3.0 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824)
0.9 2.8 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.9 8.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.9 14.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.9 4.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.9 9.7 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.9 3.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.8 2.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.8 4.2 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.8 2.4 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.8 3.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.8 7.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.8 2.3 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
0.8 3.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.7 2.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.7 3.6 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.7 10.9 GO:0042407 cristae formation(GO:0042407)
0.7 5.7 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.7 3.5 GO:0034059 response to anoxia(GO:0034059)
0.7 4.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.7 2.0 GO:2000537 T-helper 1 cell activation(GO:0035711) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) regulation of thymocyte migration(GO:2000410) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.6 3.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.6 43.5 GO:0032094 response to food(GO:0032094)
0.6 11.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 2.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6 3.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.6 4.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.6 2.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 5.1 GO:0060174 limb bud formation(GO:0060174)
0.6 6.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.6 1.7 GO:0048749 compound eye development(GO:0048749)
0.6 2.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.5 4.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.5 4.8 GO:0044351 macropinocytosis(GO:0044351)
0.5 2.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.5 17.2 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.5 4.1 GO:0070842 aggresome assembly(GO:0070842)
0.5 4.6 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.5 1.5 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.5 1.5 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) cellular response to sodium arsenite(GO:1903936) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.5 3.0 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.5 4.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.5 1.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 3.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.5 2.4 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.5 3.8 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.5 1.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.5 6.2 GO:0051639 actin filament network formation(GO:0051639)
0.5 3.8 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.5 2.4 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) negative regulation of p38MAPK cascade(GO:1903753)
0.5 3.3 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.4 1.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.4 3.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.4 1.3 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 1.7 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.4 7.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.4 3.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.4 2.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 2.8 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.4 0.8 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 3.8 GO:0007220 Notch receptor processing(GO:0007220)
0.4 4.2 GO:0006465 signal peptide processing(GO:0006465)
0.4 2.6 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.4 4.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.4 15.1 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.3 6.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.3 3.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.3 4.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.3 11.2 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.3 3.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 11.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 2.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 2.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 3.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 6.0 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.3 1.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 8.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 3.1 GO:0070995 NADPH oxidation(GO:0070995)
0.3 6.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 2.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 1.8 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.3 0.9 GO:0009992 cellular water homeostasis(GO:0009992)
0.3 4.5 GO:0002335 mature B cell differentiation(GO:0002335)
0.3 10.1 GO:0006739 NADP metabolic process(GO:0006739)
0.3 4.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 2.6 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.3 3.1 GO:0040016 embryonic cleavage(GO:0040016)
0.3 5.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.3 5.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.3 0.8 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.3 0.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3 1.8 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532) positive regulation of NFAT protein import into nucleus(GO:0051533)
0.3 6.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 7.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 3.2 GO:0051014 actin filament severing(GO:0051014)
0.2 1.9 GO:2001204 regulation of osteoclast development(GO:2001204)
0.2 0.7 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.7 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.2 2.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.2 3.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.2 0.7 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 9.4 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 4.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 6.8 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.2 2.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 2.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 1.0 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551)
0.2 7.5 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 0.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 0.6 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.2 3.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 1.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 8.3 GO:0048536 spleen development(GO:0048536)
0.2 2.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 3.1 GO:0050718 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.2 0.5 GO:0016240 autophagosome docking(GO:0016240)
0.2 0.5 GO:0035600 tRNA methylthiolation(GO:0035600)
0.2 7.6 GO:0009268 response to pH(GO:0009268)
0.2 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 20.2 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.2 2.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 0.5 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
0.2 3.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)
0.2 3.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 6.9 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.2 199.5 GO:0007608 sensory perception of smell(GO:0007608)
0.1 17.2 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 4.9 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 2.4 GO:0030903 notochord development(GO:0030903)
0.1 6.4 GO:0021762 substantia nigra development(GO:0021762)
0.1 1.0 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934)
0.1 0.9 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 1.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 5.3 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 3.4 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.0 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1 6.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 2.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 2.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.1 10.7 GO:0031638 zymogen activation(GO:0031638)
0.1 4.5 GO:0019915 lipid storage(GO:0019915)
0.1 0.9 GO:0043476 endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186)
0.1 1.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 0.2 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.1 0.8 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 1.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.1 1.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.8 GO:0007343 egg activation(GO:0007343)
0.1 1.3 GO:0051601 exocyst localization(GO:0051601)
0.1 4.0 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 2.7 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 7.1 GO:0051289 protein homotetramerization(GO:0051289)
0.1 7.7 GO:0007586 digestion(GO:0007586)
0.1 4.5 GO:0000045 autophagosome assembly(GO:0000045)
0.1 10.0 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 2.1 GO:0070207 protein homotrimerization(GO:0070207)
0.1 2.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 2.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.4 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.3 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 1.5 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.4 GO:0042501 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) serine phosphorylation of STAT protein(GO:0042501)
0.0 0.4 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 2.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 1.7 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 3.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 2.4 GO:0071773 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.5 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.6 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 3.0 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.0 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 1.0 GO:0006641 triglyceride metabolic process(GO:0006641)
0.0 0.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.4 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.0 0.0 GO:0016598 protein arginylation(GO:0016598)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0060723 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 1.3 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 0.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 42.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
5.9 17.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
3.2 9.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.8 13.9 GO:0060053 neurofilament cytoskeleton(GO:0060053)
2.5 12.5 GO:0044316 cone cell pedicle(GO:0044316)
2.2 9.0 GO:1990584 cardiac Troponin complex(GO:1990584)
1.9 15.3 GO:0005861 troponin complex(GO:0005861)
1.9 27.8 GO:0032982 myosin filament(GO:0032982)
1.6 10.9 GO:0061617 MICOS complex(GO:0061617)
1.5 4.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.2 9.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.0 21.5 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.9 2.8 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.9 2.6 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.9 6.8 GO:0044194 cytolytic granule(GO:0044194)
0.8 6.8 GO:0005577 fibrinogen complex(GO:0005577)
0.8 10.0 GO:0005687 U4 snRNP(GO:0005687)
0.8 3.9 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.8 3.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.7 6.5 GO:0061700 GATOR2 complex(GO:0061700)
0.7 8.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.7 3.5 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.7 4.2 GO:0005787 signal peptidase complex(GO:0005787)
0.7 23.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.6 1.9 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.6 3.7 GO:1990246 uniplex complex(GO:1990246)
0.6 11.6 GO:0030056 hemidesmosome(GO:0030056)
0.5 3.2 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.5 2.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.5 5.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.5 6.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 7.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.5 1.9 GO:0044299 C-fiber(GO:0044299)
0.5 6.0 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.4 3.5 GO:0005916 fascia adherens(GO:0005916)
0.4 4.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 3.3 GO:0005638 lamin filament(GO:0005638)
0.4 7.0 GO:0030061 mitochondrial crista(GO:0030061)
0.4 3.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 6.0 GO:0031045 dense core granule(GO:0031045)
0.4 8.0 GO:0043196 varicosity(GO:0043196)
0.4 1.9 GO:0035859 Seh1-associated complex(GO:0035859)
0.4 4.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 5.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 1.8 GO:0033269 internode region of axon(GO:0033269)
0.3 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.8 GO:0005955 calcineurin complex(GO:0005955)
0.3 4.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 8.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.3 13.8 GO:0016459 myosin complex(GO:0016459)
0.2 2.0 GO:0071439 CORVET complex(GO:0033263) clathrin complex(GO:0071439)
0.2 11.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 1.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 15.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 4.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 9.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 51.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 3.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.2 2.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 2.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.5 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.5 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 1.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 7.7 GO:0005811 lipid particle(GO:0005811)
0.1 4.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 9.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.6 GO:0001652 granular component(GO:0001652)
0.1 4.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 8.5 GO:0030018 Z disc(GO:0030018)
0.1 1.7 GO:0043194 axon initial segment(GO:0043194)
0.1 2.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 3.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 3.3 GO:0016235 aggresome(GO:0016235)
0.1 4.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.6 GO:0001533 cornified envelope(GO:0001533)
0.1 3.0 GO:0034704 calcium channel complex(GO:0034704)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 18.1 GO:0005874 microtubule(GO:0005874)
0.0 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 2.4 GO:0030016 myofibril(GO:0030016)
0.0 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 47.1 GO:0005615 extracellular space(GO:0005615)
0.0 17.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 24.7 GO:0005739 mitochondrion(GO:0005739)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
14.2 42.6 GO:0031720 haptoglobin binding(GO:0031720)
6.5 19.4 GO:0016748 succinyltransferase activity(GO:0016748)
3.6 21.3 GO:0004126 cytidine deaminase activity(GO:0004126)
2.9 8.8 GO:2001070 starch binding(GO:2001070)
2.7 33.0 GO:0005344 oxygen transporter activity(GO:0005344)
2.6 10.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
2.5 15.1 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
2.3 9.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
2.3 6.8 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.2 9.0 GO:0030172 troponin C binding(GO:0030172)
2.1 34.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
2.0 8.2 GO:0035877 death effector domain binding(GO:0035877)
1.7 6.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.6 4.9 GO:0031752 D5 dopamine receptor binding(GO:0031752)
1.5 9.0 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.5 4.4 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
1.4 4.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
1.3 5.3 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
1.3 14.4 GO:0016783 sulfurtransferase activity(GO:0016783)
1.2 9.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.1 3.3 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
1.1 29.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.1 6.5 GO:0070728 leucine binding(GO:0070728)
1.0 7.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.9 2.8 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.9 3.5 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 13.9 GO:0019215 intermediate filament binding(GO:0019215)
0.8 23.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.8 4.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.8 17.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.8 3.9 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.8 3.9 GO:0004974 leukotriene receptor activity(GO:0004974)
0.8 2.3 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
0.8 3.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.8 15.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.7 5.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7 4.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.7 2.8 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.7 7.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.7 4.7 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.6 2.6 GO:0036004 GAF domain binding(GO:0036004)
0.6 2.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.6 6.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 8.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.6 7.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.6 6.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.6 6.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.6 7.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.5 4.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.5 4.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.5 3.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.5 10.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.5 3.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.5 3.0 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.5 4.5 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.5 1.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.5 6.4 GO:0042301 phosphate ion binding(GO:0042301)
0.4 1.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 12.5 GO:0030552 cAMP binding(GO:0030552)
0.4 6.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.4 4.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 3.3 GO:0005521 lamin binding(GO:0005521)
0.4 12.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4 3.6 GO:0015266 protein channel activity(GO:0015266)
0.4 3.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.4 5.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 3.8 GO:0050897 cobalt ion binding(GO:0050897)
0.3 11.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 1.7 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.3 1.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.3 2.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 2.2 GO:0035375 zymogen binding(GO:0035375)
0.3 3.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 1.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 3.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.5 GO:0019770 IgG receptor activity(GO:0019770)
0.3 4.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 2.4 GO:0031404 chloride ion binding(GO:0031404)
0.3 1.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 8.0 GO:0043531 ADP binding(GO:0043531)
0.3 0.8 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.3 2.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.3 10.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 2.0 GO:0004966 galanin receptor activity(GO:0004966)
0.3 1.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 7.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 2.0 GO:0034046 poly(G) binding(GO:0034046)
0.2 9.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.0 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.2 0.7 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 0.7 GO:0042806 fucose binding(GO:0042806)
0.2 2.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 6.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.9 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 4.1 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2 3.6 GO:0000146 microfilament motor activity(GO:0000146)
0.2 19.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 3.0 GO:0015643 toxic substance binding(GO:0015643)
0.2 4.1 GO:0070628 proteasome binding(GO:0070628)
0.2 51.8 GO:0008236 serine-type peptidase activity(GO:0008236)
0.2 2.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 20.7 GO:0051117 ATPase binding(GO:0051117)
0.2 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 0.5 GO:0035596 methylthiotransferase activity(GO:0035596) transferase activity, transferring alkylthio groups(GO:0050497)
0.2 3.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 3.1 GO:0070402 NADPH binding(GO:0070402)
0.2 2.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 1.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 3.1 GO:0005537 mannose binding(GO:0005537)
0.2 3.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 1.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 2.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 63.3 GO:0005549 odorant binding(GO:0005549)
0.2 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.7 GO:0031005 filamin binding(GO:0031005)
0.1 10.9 GO:0032947 protein complex scaffold(GO:0032947)
0.1 3.4 GO:0071949 FAD binding(GO:0071949)
0.1 2.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 10.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 3.1 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 3.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 115.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 5.5 GO:0051018 protein kinase A binding(GO:0051018)
0.1 4.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 9.9 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 20.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 23.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 0.6 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.2 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.1 9.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 5.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 0.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 22.3 GO:0030246 carbohydrate binding(GO:0030246)
0.1 3.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 6.5 GO:0030674 protein binding, bridging(GO:0030674)
0.1 24.8 GO:0003779 actin binding(GO:0003779)
0.1 2.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.3 GO:0031489 myosin V binding(GO:0031489)
0.1 1.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 7.3 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.2 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 7.4 GO:0005179 hormone activity(GO:0005179)
0.0 2.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 3.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 3.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 1.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 3.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 10.8 GO:0008047 enzyme activator activity(GO:0008047)
0.0 14.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 8.7 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 1.2 GO:0002020 protease binding(GO:0002020)
0.0 0.5 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.0 GO:0008017 microtubule binding(GO:0008017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 8.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 2.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 8.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4 17.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 18.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 5.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 21.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 3.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 6.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 8.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 3.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 4.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 4.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 7.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 4.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 6.8 PID BCR 5PATHWAY BCR signaling pathway
0.1 7.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 2.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.3 PID AP1 PATHWAY AP-1 transcription factor network
0.1 6.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 81.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
2.1 4.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
1.5 21.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.3 15.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.1 19.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.1 10.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.9 6.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.8 7.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.7 12.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.7 18.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 10.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.6 10.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.6 22.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.5 6.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5 8.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 6.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.5 9.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.5 27.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 6.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 6.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.4 3.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.4 3.9 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.3 4.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 6.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 4.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 4.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 7.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 3.9 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 4.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.3 7.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 5.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 4.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 8.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 3.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 14.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 6.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 4.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 8.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 2.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 7.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 2.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 1.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 5.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 2.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 6.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 10.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 11.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 13.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 4.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 7.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 2.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 6.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 2.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 3.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 8.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 4.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 3.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation